CAS 951-78-0

Desoxiuridina

Descripción:

Desoxiuridina es un nucleósido que juega un papel crucial en la síntesis de ADN. Consiste en una molécula de azúcar desoxirribosa unida a una base de uracilo, que es una de las cuatro nucleobases que se encuentran en el ARN, pero en el ADN, se reemplaza por timina. La fórmula química de Desoxiuridina es C9H11N2O5, y tiene un peso molecular de aproximadamente 227.24 g/mol. Desoxiuridina es típicamente un polvo cristalino blanco a blanco sucio que es soluble en agua y exhibe un pH ligeramente ácido a neutro en solución. Está involucrado en varios procesos bioquímicos, incluida la replicación y reparación del ADN, y sirve como sustrato para la enzima timidina quinasa, que lo fosforila para formar triphosphate de Desoxiuridina (dUTP). Este compuesto también es de interés en investigaciones y aplicaciones terapéuticas, particularmente en el estudio del metabolismo de ácidos nucleicos y como un posible agente antiviral. Su número CAS es 951-78-0, que lo identifica de manera única en bases de datos químicas.

Fórmula: C₉H₁₂N₂O₅

InChI: InChI=1S/C9H12N2O5/c12-4-6-5(13)3-8(16-6)11-2-1-7(14)10-9(11)15/h1-2,5-6,8,12-13H,3-4H2,(H,10,14,15)/t5-,6+,8+/m0/s1

Clave InChI: InChIKey=MXHRCPNRJAMMIM-SHYZEUOFSA-N

SMILES: O=C1N([C@@H]2O[C@H](CO)[C@@H](O)C2)C=CC(=O)N1

Sinónimos:

• 1-(2-Deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)uracil
• 1-(2-Deoxy-β-D-erythro-pentofuranosyl)uracil
• 1-(2-deoxy-alpha-L-erythro-pentofuranosyl)pyrimidine-2,4(1H,3H)-dione
• 1-(2-deoxy-beta-L-erythro-pentofuranosyl)pyrimidine-2,4(1H,3H)-dione
• 1-(2-deoxypentofuranosyl)pyrimidine-2,4(1H,3H)-dione
• 1-[(3xi)-2-deoxy-beta-D-glycero-pentofuranosyl]pyrimidine-2,4(1H,3H)-dione
• 2'-Desoxiuridina
• 2'-Desoxyuridin
• 2'-Desoxyuridine
• 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-
• 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-
• 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-D-erythro-pentofuranosyl)-
• 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-D-ribofuranosyl)-
• Deoxyribose uracil
• Deoxyuridine
• Nsc 23615
• Uracil deoxyriboside
• Uridine, 2'-deoxy-
• 2-Deoxyuridine

2'-Deoxyuridine

CAS: 951-78-0

Fórmula: C₉H₁₂N₂O₅

Pureza: >99.0%(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 228.20

Ref: 3B-D0060

2'-Deoxyuridine, 98+%

CAS: 951-78-0

2'-Deoxyuridine is frequently halogenated to create thymidine analogues useful for studies of DNA synthesis and degradation mechanisms. Derivatized 2?-Deoxyuridines used as labeling substrates include chloro-2?-deoxyuridine (CldU), bromodeoxyuridine (BrdU) and/or iododeoxyuridine (IdU). Other useful

Fórmula: C₉H₁₂N₂O₅

Pureza: 98+%

Forma y color: Crystals or powder or crystalline powder, White to pale cream

Peso molecular: 228.20

Ref: 02-A16026

1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione

CAS: 951-78-0

Fórmula: C₉H₁₂N₂O₅

Pureza: 98%

Forma y color: Solid

Peso molecular: 228.2020

Ref: IN-DA005T5P

2'-Deoxyuridine

CAS: 951-78-0

2'-Deoxyuridine (2-deoxyuridine).

Fórmula: C₉H₁₂N₂O₅

Pureza: 98.51% - 99.88%

Forma y color: Solid

Peso molecular: 228.2

Ref: TM-T1721

2'-Deoxyuridine

CAS: 951-78-0

2'-Deoxyuridine

Pureza: ≥98%

Peso molecular: 228.2g/mol

Ref: 54-BUP15860

2'-Deoxyuridine

CAS: 951-78-0

2'-Deoxyuridine

Fórmula: C₉H₁₂N₂O₅

Pureza: ≥95%

Forma y color: white crystalline powder

Peso molecular: 228.20g/mol

Ref: 54-OR0326

2'-Deoxyuridine-2-13C;1,3-15N

CAS: 369656-76-8, 951-78-0

Pureza: 99 atom % 13C; 99 atom % 15N

Forma y color: White Solid

Peso molecular: 231.23

Ref: 3U-M5445

2'-Desoxyuridine

CAS: 951-78-0

Fórmula: C₉H₁₂N₂O₅

Pureza: 95%~99%

Peso molecular: 228.204

Ref: BP-BP4234

2''-Deoxyuridine

CAS: 951-78-0

Fórmula: C₉H₁₂N₂O₅

Pureza: ≥ 99.0%

Forma y color: White to off-white crystalline powder

Peso molecular: 228.21

Ref: 7W-GE3235

2’-Deoxyuridine

CAS: 951-78-0

Applications An uridine derivative as therapeutic agent for treating allergy, cancer, infection and autoimmune disease.
References Fu, M., et al.: J. Biol. Chem., 271, 9982 (1996), Thornalley, P., et al.: Biochem. J., et al.: 344, 109 (1999), Munter, T., et al.: Chem. Res. Toxicol., 15, 1549 (2002)

Fórmula: C₉H₁₂N₂O₅

Forma y color: Neat

Peso molecular: 228.20

Ref: TR-D288010

2'-Deoxyuridine

CAS: 951-78-0

2'-Deoxyuridine (2'-dU) is an intermediate in the synthesis of thymidylate, which is a precursor for DNA synthesis. It can be prepared through high-performance liquid chromatography. 2'-dU has been shown to inhibit the enzymatic activity of enzymes responsible for synthesizing uridine and thymidylate, leading to neuronal death. 2'-dU has also been shown to have a protective effect against mitochondrial dysfunction induced by hydrogen fluoride. It is also known to bind with toll-like receptor 4 (TLR4), which is involved in inflammatory responses. 2'-dU has been used as a fluorescence probe for nucleic acids and as a polymerase chain reaction (PCR) substrate.

Fórmula: C₉H₁₂N₂O₅

Pureza: Min. 98 Area-%

Forma y color: White Powder

Peso molecular: 228.21 g/mol

Ref: 3D-ND06282

1-((2R,4S,5R)-4-Hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

CAS: 951-78-0

Fórmula: C₉H₁₂N₂O₅

Pureza: 97%

Forma y color: Solid, Crystalline Powder

Peso molecular: 228.204

Ref: 10-F093489

2’-Deoxyuridine extrapure, 98%

CAS: 951-78-0

Fórmula: C₉H₁₂N₂O₅

Peso molecular: 228.20

Ref: SR-92627

2'-Deoxyuridine

CAS: 951-78-0

Please enquire for more information about 2'-Deoxyuridine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Fórmula: C₉H₁₂N₂O₅

Pureza: Min. 98 Area-%

Peso molecular: 228.2 g/mol

Ref: 3D-Q-200273

Trifluridine EP Impurity D

CAS: 951-78-0

Fórmula: C₉H₁₂N₂O₅

Peso molecular: 228.2

Ref: ST-EA-CP-T185004