CAS 956025-99-3

3-(3-Bromobenzyl)-1-(tert-butyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

CAS: 956025-99-3

3-(3-Bromobenzyl)-1-(tert-butyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Pureza: 98%

Peso molecular: 360.26g/mol

Ref: 54-OR1073856

4-Amino-1-tert-butyl-3-(3-bromobenzyl)pyrazolo[3,4-d]pyrimidine

Producto controlado

CAS: 956025-99-3

Applications 4-Amino-1-tert-butyl-3-(3-bromobenzyl)pyrazolo[3,4-d]pyrimidine is a small molecule Akt inhibitor. The kinase Akt is a key signaling node in regulating cellular growth and survival.
References Eblen, S., et al.: J. Biol. Chem., 278, 14926 (2003), Lindsley, C., et al.: Bioorg. Med. Chem. Lett., 15, 761 (2005), Manning, B., et al.: Cell, 129, 1261 (2007), Heerding, D., et al.: J. Med. Chem., 51, 5663 (2008),

Fórmula: C₁₆H₁₈BrN₅

Forma y color: Neat

Peso molecular: 360.25

Ref: TR-A602985

3BrB-PP1

CAS: 956025-99-3

3BrB-PP1 is an ATP-competitive analog that exhibits specific inhibitory activity towards protein kinase, particularly effective against protein kinases with mutations in the ATP-binding pocket, such as the Thr97 mutation within Sty1's ATP-binding pocket.

Fórmula: C₁₆H₁₈BrN₅

Forma y color: Solid

Peso molecular: 360.259

Ref: TM-T41113