CAS 957-68-6
:Ácido 7-aminocefalosporánico
Descripción:
Ácido 7-aminocefalosporánico (7-ACA) es un intermediario crucial en la síntesis de antibióticos cefalosporínicos, que se utilizan ampliamente para tratar infecciones bacterianas. Es un compuesto bicíclico que presenta un anillo beta-lactámico, característico de los antibióticos beta-lactámicos, que es esencial para su actividad antibacteriana. La estructura molecular de 7-ACA incluye un grupo amino en la posición 7, lo que mejora su reactividad y permite modificaciones químicas adicionales para crear varios derivados de cefalosporina. Este compuesto es típicamente un polvo cristalino blanco a blanco amarillento, soluble en agua y solventes orgánicos polares, y exhibe estabilidad en condiciones ácidas, pero puede ser hidrolizado en ambientes alcalinos. Su mecanismo antibacteriano implica la inhibición de la síntesis de la pared celular bacteriana, lo que lo hace efectivo contra un amplio espectro de bacterias Gram-positivas y algunas Gram-negativas. Debido a su importancia en aplicaciones farmacéuticas, 7-ACA es un bloque de construcción clave en el desarrollo de nuevos antibióticos, contribuyendo a los esfuerzos en curso para combatir la resistencia a los antibióticos.
Fórmula:C10H12N2O5S
InChI:InChI=1S/C10H12N2O5S/c1-4(13)17-2-5-3-18-9-6(11)8(14)12(9)7(5)10(15)16/h6,9H,2-3,11H2,1H3,(H,15,16)/t6-,9-/m1/s1
Clave InChI:InChIKey=HSHGZXNAXBPPDL-HZGVNTEJSA-N
SMILES:C(O)(=O)C=1N2[C@@]([C@H](N)C2=O)(SCC1COC(C)=O)[H]
Sinónimos:- (6R,7R)-3-[(acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- (6R-trans)-3-[(Acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- (7R)-7-Aminocephalosporanic acid
- 3-(Acetoxymethyl)-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- 3-(Acetoxymethyl)-7-aminocephem-4-carboxylic acid
- 3-Acetoxymethyl-7-aminoceph-3-em-4-carboxylic acid
- 3-Acetoxymethyl-7β-aminoceph-3-em-4-carboxylic acid
- 3-Acetoxymethylen-7-Amino-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid
- 3-Acetoxymethylen-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-2-carbonsaure
- 3-[(Acetyloxy)Methyl]-7-Amino-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-amino-8-oxo-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-amino-8-oxo-, (6R,7R)-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 3-[(acetyloxy)methyl]-7-amino-8-oxo-, (6R-trans)-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-amino-3-(hydroxymethyl)-8-oxo-, acetate (ester)
- 7-Aca
- 7-Acs
- 7-Amino Cephalosporanic Acid
- 7-Amino-3-acetoxymethyl-3-cephem-4-carboxylic acid
- 7-Amino-3-acetoxymethyl-Δ-3-cephem-4-carboxylic acid
- 7-Amino-3-acetoxymethyl-Δ3-cephem-4-carboxylic acid
- 7-Amino-3-acetoxymethyl-Δ<sup>3</sup>-cephem-4-carboxylic acid
- 7β-Amino-3-acetoxymethylcephemcarboxylic acid
- 7β-Aminocephalosporanic acid
- Acide 3-Acetoxymethylene-7-Amino-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylique
- Acido 3-Acetoximetilen-7-Amino-8-Oxo-5-Tia-1-Azabiciclo[4.2.0]Oct-2-Eno-2-Carboxilico
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Encontrado 16 productos.
7-Aminocephalosporanic Acid
CAS:Fórmula:C10H12N2O5SPureza:>97.0%(T)(HPLC)Forma y color:White to Light yellow to Light orange powder to crystalPeso molecular:272.287-Aminocephalosporanic acid
CAS:Fórmula:C10H12N2O5SPureza:95%Forma y color:SolidPeso molecular:272.27777-Aminocephalosporanic acid
CAS:7-Aminocephalosporanic acid (7-ACA) is used for synthesis of cephalosporin antibiotics and intermediates.Fórmula:C10H12N2O5SPureza:91.05%Forma y color:White Solid PowderPeso molecular:272.287-Aminocephalosporanic acid
CAS:Fórmula:C10H12N2O5SPureza:(HPLC) ≥ 95.0%Forma y color:White to off-white or beige crystalline powderPeso molecular:272.28Cefazolin EP Impurity H (Cefalotin EP Impurity C, Cefoperazone EP Impurity E, 7-Aminocephalosporanic Acid)
CAS:Fórmula:C10H12N2O5SForma y color:White To Off-White SolidPeso molecular:272.287-Aminocephalosporanic acid
CAS:7-Aminocephalosporanic acidPureza:96.4% (hplc) (Typical Value in Batch COA)Forma y color: slightly off-white crystalline powderPeso molecular:272.28g/mol(6R,7R)-3-[(Acetyloxy)methyl]-7-amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid (7-ACA)
CAS:Producto controladoFórmula:C10H12N2O5SForma y color:NeatPeso molecular:272.287-Aminocephalosporanic acid
CAS:Fórmula:C10H12N2O5SPureza:95%Forma y color:Solid, PowderPeso molecular:272.287-Aminocephalosporanic Acid
CAS:Producto controladoImpurity Cefoperazone EP Impurity E
Stability Hygroscopic
Applications 7-Aminocephalosporanic Acid (Cefoperazone EP Impurity E) is the starting material for semi-synthetic cephalosporins. Obtained by mild acid hydrolysis of cephalosporin C.
References Matsuda, A., et al.: J. Bacteriol., 169, 5815 (1987), Aramori, I., et al.: J. Ferment. Bioeng., 72, 227 (1991), Park, S., et al.: J. Biosci. Bioeng., 94, 218 (2002), Takimoto, A., et al.: Appl. Microbiol. Biotechnol., 65, 263 (2004),Fórmula:C10H12N2O5SForma y color:White To Light YellowPeso molecular:272.287-Aminocephalosporanic acid
CAS:7-Aminocephalosporanic acid is a molecule that can be used for wastewater treatment. It is an antibiotic with a broad spectrum of activity against bacteria and fungi, as well as some viruses. 7-Aminocephalosporanic acid has been shown to have antimicrobial properties in the human serum and to bind to the α subunit of cephalosporin, which is involved in bacterial cell wall synthesis. This compound contains nitrogen atoms with high biological reactivity, which may be due to its ability to form disulfide bonds on protein surfaces.
Fórmula:C10H12N2O5SPureza:Min. 95%Forma y color:PowderPeso molecular:272.28 g/molRef: 3D-FA11814
Producto descatalogado7-Aminocephalosporanic acid, Antibiotic for Culture Media Use Only
CAS:7-Aminocephalosporanic acid is a chemical compound that is used as a reactant in the production of other chemicals.
Fórmula:C10H12N2O5SPeso molecular:272.28 g/mol
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