CAS 957-75-5

5-Bromouridina

Descripción:

5-Bromouridina es un análogo de nucleósido de uridina, caracterizado por la presencia de un átomo de bromo en la posición 5 de la base de uracilo. Su fórmula molecular es C₁₁H₁₄BrN₃O₅, y tiene un peso molecular que refleja su estructura. Este compuesto es conocido por su papel en la investigación bioquímica, particularmente en estudios relacionados con la síntesis de ARN y la actividad antiviral. 5-Bromouridina puede ser incorporado en el ARN en lugar de uridina, lo que puede afectar la función y estabilidad de las moléculas de ARN. Exhibe propiedades típicas de los nucleósidos, incluida la capacidad de formar enlaces de hidrógeno y participar en el emparejamiento de bases. Además, 5-Bromouridina ha sido investigado por sus posibles aplicaciones terapéuticas, particularmente en el contexto de infecciones virales y tratamiento del cáncer, debido a su capacidad para interferir con el metabolismo de los ácidos nucleicos. Su solubilidad y estabilidad en varios disolventes lo convierten en un compuesto útil en entornos de laboratorio para estudiar interacciones y funciones de los ácidos nucleicos.

Fórmula: C₉H₁₁BrN₂O₆

InChI: InChI=1S/C9H11BrN2O6/c10-3-1-12(9(17)11-7(3)16)8-6(15)5(14)4(2-13)18-8/h1,4-6,8,13-15H,2H2,(H,11,16,17)/t4-,5-,6-,8-/m1/s1

Clave InChI: InChIKey=AGFIRQJZCNVMCW-UAKXSSHOSA-N

SMILES: O[C@H]1[C@@H](O[C@H](CO)[C@H]1O)N2C(=O)NC(=O)C(Br)=C2

Sinónimos:

• 1-beta-Ribofuranosyl-5-bromo-uracil
• 4-Amino-5-bromo-1-[3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one
• 5-Bromouracil ribonucleoside
• 5-bromo-1-pentofuranosylpyrimidine-2,4(1H,3H)-dione
• Brn 0033664
• Nsc 38296
• Uridine, 5-bromo-
• 5-Bromouridine
• 5-24-06-00337 (Beilstein Handbook Reference)
• (-)-5-Bromouridine
• 5-Bromo-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
• 5-BrU
• 5-BROMOURIDINE (5-BROMOURACIL-1-β-D-RIBOFURANOSIDE: 5-BRU)
• 5-BROMO-URIDINE(5-BRU)
• 5-Bromo-D-uridine
• 5-bromouracil-1-β-d-ribofuranoside
• 5-BROMOURIDINE extrapure
• 5-Bromouridine, 99+%
• 5-Bromouracil-1-β-D-ribofuranoside, 5-Bromouridine
• 5-BROMOURACIL-1-BETA-D-RIBOFURANOSIDE
• 5-Bromouridine,98%

5-Bromouridine, 98%

CAS: 957-75-5

5-Bromouridine is often incorporated into RNA in order to detect immunocytochemically and analyzed by cytometry. It possesses anti-viral activity and inhibits the activity of viruses such as human immunodeficiency virus. This Thermo Scientific Chemicals brand product was originally part of the Alfa

Fórmula: C₉H₁₁BrN₂O₆

Pureza: 98%

Forma y color: White, Powder

Peso molecular: 323.10

Ref: 02-A18507

5-Bromo-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione

CAS: 957-75-5

Fórmula: C₉H₁₁BrN₂O₆

Pureza: 97%

Forma y color: Solid

Peso molecular: 323.0974

Ref: IN-DA006AZM

5-Bromouridine

CAS: 957-75-5

5-Bromouridine

Pureza: 98%

Peso molecular: 323.10g/mol

Ref: 54-OR1011840

5-Bromouridine

CAS: 957-75-5

Fórmula: C₉H₁₁BrN₂O₆

Pureza: >99.0%(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 323.10

Ref: 3B-B0666

5-Bromouridine

CAS: 957-75-5

Fórmula: C₉H₁₁BrN₂O₆

Peso molecular: 323.10

Ref: 7W-GN9949

5-Bromouridine

CAS: 957-75-5

5-Bromouridine is a antitumor uracil derivative that induces apoptosis in cancer cells by inhibiting DNA synthesis and is also a marker for DNA and RNA.

Fórmula: C₉H₁₁BrN₂O₆

Pureza: 99.89%

Forma y color: White Powder

Peso molecular: 323.1

Ref: TM-T36894

5-Bromouridine

CAS: 957-75-5

5-Bromouridine is an energy-related metabolite that is a precursor of uridine. It is a nucleotide base that is incorporated into DNA during DNA replication. 5-Bromouridine has been shown to have radiation resistance and high resistance to viral life. It also binds to the nuclear DNA in cells, where it can act as a transcriptional regulator. 5-Bromouridine is used in the treatment of malignant brain tumors, where it can inhibit tumor growth by binding to the dna of cancer cells and preventing the synthesis of proteins required for cell division. 5-Bromouridine binds with high affinity to basic fibroblast, which may be related to its effects on cancer cells.

Fórmula: C₉H₁₁BrN₂O₆

Pureza: Min. 95%

Forma y color: White Powder

Peso molecular: 323.1 g/mol

Ref: 3D-NB03843

5-Bromouridine

CAS: 957-75-5

Fórmula: C₉H₁₁BrN₂O₆

Pureza: 97%

Forma y color: Solid

Peso molecular: 323.099

Ref: 10-F050870

5-Bromouridine extrapure, 99%

CAS: 957-75-5

Fórmula: C₉H₁₁BrN₂O₆

Pureza: min. 99%

Forma y color: White to off-white, Powder or crystals

Peso molecular: 323.11

Ref: SR-12211

5-Bromouridine

Producto controlado

CAS: 957-75-5

Applications 5-Bromouridine is a uridine (U829910) derivative and is often incorporated into RNA in order to detect immunocytochemically and analyzed by cytometry.
References Kramer, K., et al.: Int. J. Mass. Spect., 304, 184 (2011); Denifi, S., et al.: Euro. Phys. J. Atomic. Molec. Optical. Phys., 35, 391 (2005);

Fórmula: C₉H₁₁BrN₂O₆

Forma y color: Neat

Peso molecular: 323.1

Ref: TR-B688960