CAS 96426-21-0

glicina-arginina-glicina-ácido aspártico-serina

Descripción:

La sustancia química conocida como "glicina-arginina-glicina-ácido aspártico-serina," con el número CAS 96426-21-0, es un péptido compuesto por cuatro aminoácidos: glicina (Gly), arginina (Arg), ácido aspártico (Asp) y serina (Ser). Este péptido es notable por su papel en procesos biológicos, particularmente en la adhesión celular y la señalización. La secuencia de aminoácidos contribuye a sus propiedades estructurales y funcionales, haciéndolo relevante en diversas aplicaciones bioquímicas, incluyendo el desarrollo de fármacos y la ingeniería de tejidos. glicina-arginina-glicina-ácido aspártico-serina puede interactuar con receptores o proteínas específicos, influyendo en el comportamiento y las respuestas celulares. Su tamaño relativamente pequeño permite una fácil síntesis y modificación, lo que es ventajoso en contextos de investigación y terapéuticos. Además, la presencia de cadenas laterales cargadas y polares en los aminoácidos puede afectar la solubilidad y la interacción con otras biomoléculas. En general, este péptido sirve como un modelo valioso para estudiar las interacciones y funciones de los péptidos en sistemas biológicos.

Fórmula: C₁₇H₃₀N₈O₉

InChI: InChI=1/C17H30N8O9/c18-5-11(27)23-8(2-1-3-21-17(19)20)14(31)22-6-12(28)24-9(4-13(29)30)15(32)25-10(7-26)16(33)34/h8-10,26H,1-7,18H2,(H,22,31)(H,23,27)(H,24,28)(H,25,32)(H,29,30)(H,33,34)(H4,19,20,21)/t8-,9-,10-/m0/s1

SMILES: C(C[C@@H](C(=NCC(=N[C@@H](CC(=O)O)C(=N[C@@H](CO)C(=O)O)O)O)O)N=C(CN)O)CNC(=N)N

Sinónimos:

• H-Gly-Arg-Gly-Asp-Ser-OH
• glycyl-N~5~-(diaminomethylidene)-L-ornithylglycyl-L-alpha-aspartyl-L-serine

H-Gly-Arg-Gly-Asp-Ser-OH

CAS: 96426-21-0

GRGDS, a fragment derived from the cell binding region of fibronectin. Inhibitor of thrombin-induced platelet aggregation.

Fórmula: C₁₇H₃₀N₈O₉

Pureza: 96.7%

Forma y color: White Lyophilisate

Peso molecular: 490.47

Ref: 01-4008998

Gly-Arg-Gly-Asp-Ser

CAS: 96426-21-0

Fórmula: C₁₇H₃₀N₈O₉

Pureza: 98%

Peso molecular: 490.4683

Ref: IN-DA019FVU

Gly-Arg-Gly-Asp-Ser

CAS: 96426-21-0

Gly-Arg-Gly-Asp-Ser (GRGDS) GRGDS is a cell binding protein domain derived from the cell-binding region of fibronectin.

Fórmula: C₁₇H₃₀N₈O₉

Pureza: 98%

Forma y color: Solid

Peso molecular: 490.47

Ref: TM-TP1459

Gly-Arg-Gly-Asp-Ser

CAS: 96426-21-0

Fórmula: C₁₇H₃₀N₈O₉

Peso molecular: 490.47

Ref: 7W-GL3717

Fibronectin Active Fragment (GRGDS)

CAS: 96426-21-0

Fibronectin is an extracellular matrix protein that plays a critical role in cell adhesion, migration, and differentiation. Fibronectin subunits are composed of repeating units of three types of modules: type I, type II, and type III. The active fragment of fibronectin refers to a small peptide sequence within the type III modules of fibronectin that has been shown to have potent biological activity.
The fibronectin active fragment, also known as the cell-binding domain or RGD domain, is a short peptide sequence consisting of the amino acid sequence Arg-Gly-Asp (RGD). This peptide sequence interacts with cell surface receptors known as integrins, which are important for mediating cell adhesion, migration, and signaling.
The fibronectin active fragment has been extensively studied as a research tool to investigate the mechanisms of cell adhesion and migration. It has also been used in tissue engineering applications to promote cell attachment and proliferation on synthetic biomaterials.

Fórmula: C₁₇H₃₀N₈O₉CH₃COOHH₂O

Pureza: Min. 95%

Peso molecular: 490.47 g/mol

Ref: 3D-PFA-4189

Fibronectin Active Fragment (GRGDS)

CAS: 96426-21-0

Fibronectin is an extracellular matrix protein that plays a critical role in cell adhesion, migration, and differentiation. Fibronectin subunits are composed of repeating units of three types of modules: type I, type II, and type III. The active fragment of fibronectin refers to a small peptide sequence within the type III modules of fibronectin that has been shown to have potent biological activity.
The fibronectin active fragment, also known as the cell-binding domain or RGD domain, is a short peptide sequence consisting of the amino acid sequence Arg-Gly-Asp (RGD). This peptide sequence interacts with cell surface receptors known as integrins, which are important for mediating cell adhesion, migration, and signaling.
The fibronectin active fragment has been extensively studied as a research tool to investigate the mechanisms of cell adhesion and migration. It has also been used in tissue engineering applications to promote cell attachment and proliferation on synthetic biomaterials. This product is available as a 0.5mg vial.

Fórmula: C₁₇H₃₀N₈O₉

Pureza: Min. 95%

Peso molecular: 490.47 g/mol

Ref: 3D-PFA-4189-V

H-Gly-Arg-Gly-Asp-Ser-OH TFA salt

CAS: 96426-21-0

H-Gly-Arg-Gly-Asp-Ser-OH TFA salt is a synthetic peptide that is designed to bind to the nuclear factor kappa B (NFκB) and inhibit its activation. NFκB is a transcription factor that regulates gene expression in response to various stimuli, including proinflammatory cytokines, oxidants, and electrophilic compounds. H-Gly-Arg-Gly-Asp-Ser-OH TFA salt has been shown to inhibit NFκB activation in a model system. This molecule also inhibits axonal growth and pluripotent cells differentiation, which may be due to its suppression of the signal peptide. The rate constant for this drug has been measured using polymer compositions and biocompatible polymers.

Fórmula: C₁₇H₃₀N₈O₉(freebase)

Pureza: Min. 95%

Peso molecular: 490.47 g/mol

Ref: 3D-FG108418