CAS 979-92-0

L-Homocisteína, S-(5'-desoxiadenosin-5'-il)-

Descripción:

L-Homocisteína, S-(5'-desoxiadenosin-5'-il)-, también conocido por su número CAS 979-92-0, es un derivado de aminoácido que contiene azufre y juega un papel significativo en varios procesos bioquímicos, particularmente en el metabolismo de la homocisteína. Este compuesto se caracteriza por la presencia de un esqueleto de homocisteína unido a un moiety de 5'-deoxiadenosina, que es crucial para su actividad biológica. Típicamente está involucrado en reacciones de metilación y es un intermediario clave en la vía de transulfuración, influyendo en la síntesis de cisteína y otras biomoléculas importantes. El compuesto es soluble en agua y exhibe características polares debido a la presencia de grupos funcionales amino y carboxilo. Su importancia biológica se subraya por su participación en la salud cardiovascular, ya que niveles elevados de homocisteína están asociados con un mayor riesgo de enfermedades cardiovasculares. Además, los derivados de L-homocisteína se estudian por sus posibles roles en la señalización celular y como biomarcadores para diversas condiciones de salud.

Fórmula: C₁₄H₂₀N₆O₅S

InChI: InChI=1S/C14H20N6O5S/c15-6(14(23)24)1-2-26-3-7-9(21)10(22)13(25-7)20-5-19-8-11(16)17-4-18-12(8)20/h4-7,9-10,13,21-22H,1-3,15H2,(H,23,24)(H2,16,17,18)/t6-,7+,9+,10+,13+/m0/s1

Clave InChI: InChIKey=ZJUKTBDSGOFHSH-WFMPWKQPSA-N

SMILES: O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](CSCC[C@@H](C(O)=O)N)[C@H]1O

Sinónimos:

• (S)-5'-(S)-(3-Amino-3-carboxypropyl)-5'-thioadenosin
• (S)-5'-(S)-(3-amino-3-carboxipropil)-5'-tioadenosina
• (S)-5'-(S)-(3-amino-3-carboxypropyl)-5'-thioadenosine
• <span class="text-smallcaps">L</span>-Homocysteine, S-(5′-deoxyadenosin-5′-yl)-
• <span class="text-smallcaps">L</span>-S-Adenosylhomocysteine
• Adenosine, 5'-S-(3-amino-3-carboxypropyl)-5'-thio-, L-
• Adenosine, 5′-S-(3-amino-3-carboxypropyl)-5′-thio-, <span class="text-smallcaps">L</span>-
• Adenosyl-<span class="text-smallcaps">L</span>-homocysteine
• Adenosyl-L-homocysteine
• Adenosylhomocysteine
• Homocysteine, S-adenosyl-, <span class="text-smallcaps">L</span>-
• Homocysteine, S-adenosyl-, L-
• L-S-Adenosylhomocysteine
• S-(5'-Adenosyl)-L-homocysteine
• S-(5′-Adenosyl)-<span class="text-smallcaps">L</span>-homocysteine
• S-(5′-Deoxyadenosin-5′-yl)-<span class="text-smallcaps">L</span>-homocysteine
• S-Adenosyl-<span class="text-smallcaps">L</span>-homocysteine
• S-Adenosyl-L-homocysteine
• S-Adenosylhomocysteine
• SAH (S-Adenosylhomocysteine)
• L-Homocysteine, S-(5′-deoxyadenosin-5′-yl)-
• S-(5′-Deoxyadenosin-5′-yl)-L-homocysteine
• (2S)-2-amino-4-({[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}sulfanyl)butanoic acid (non-preferred name)
• 2-amino-4-({[5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl}sulfanyl)butanoic acid (non-preferred name)
• L-Homocysteine, S-(5'-deoxyadenosin-5'-yl)-
• 5'-Deoxy-s-adenosyl-L-homocysteine
• S-Adenosyl-L-homocystein
• AdenosylhoMocysteine-13C5
• S-(5'-Deoxyadenosin-5'-yl)-L-hoMocysteine-13C5
• 5μ-Deoxy-S-adenosyl-L-homocysteine, AdoHcy, S-(5μ-Deoxyadenosine-5μ)-L-homocysteine
• Adenosyl-L-hoMocysteine-13C5
• S-(5′
• (S)-2-amino-4-((((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)thio)butanoic acid
• S-Adenosyl-L-Homocysteine (50 mg)
• L-5'-S-(3-AMino-3-carboxypropyl)-
• (2S)-2-amino-4-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methylsulfanyl]butanoic acid
• ADOHCY
• S-(5'-DEOXYADENOSINE-5')-L-HOMOCYSTEINE
• L
• S-(5'-deoxyadenosin-5'-yl)
• -homocysteine
• 5'-thioadenosine-13C5
• L-S-AdenosylhoMocysteine-13C5
• -Adenosyl)-
• hpce
• S-(5′-Adenosyl)-L-homocysteine,5′-Deoxy-S-adenosyl-L-homocysteine, AdoHcy, S-(5′-Deoxyadenosine-5′)-L-homocysteine
• S-ADENOSYL-L-HOMOCYSTEINE (ADENOSINE-13C10, 98%)
• ( 35 ) -5-( 3-AMINO.-3 CARBOXYPROPYL) THIO ) -5-DEOXYADENOSINE
• 5'-DEOXY-S-ADENOSYL-
• S-(5'-Deoxyadenosine)-L-homocysteine
• S-(5'-Adenosyl)-L-homocysteine dihydrate
• S-(5'-Adenosyl)-L-homocysteine;AdoHcy;S-(5'-Deoxyadenosine)-L-homocysteine
• 5'-DEOXY-S-ADENOSYL-L-HOMOCYSTEINE USP/EP/BP
• HOMOCYSTEINE, S-ADENOSYL
• 5'-thioadenosine
• Ademetionine 1,4-Butanedisulfonate Impurity 1

S-Adenosyl-L-Homocysteine

CAS: 979-92-0

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Fórmula: C₁₄H₂₀N₆O₅S

Forma y color: White Crystalline Powder

Peso molecular: 384.12159

Ref: 45-1012112

S-Adenosyl-L-homocysteine

CAS: 979-92-0

Fórmula: C₁₄H₂₀N₆O₅S

Pureza: 97%

Forma y color: Solid

Peso molecular: 384.4108

Ref: IN-DA006AE7

S-Adenosyl-L-Homocysteine

CAS: 979-92-0

Fórmula: C₁₄H₂₀N₆O₅S

Peso molecular: 384.41

Ref: 4Z-C-7727

S-Adenosylhomocysteine

CAS: 979-92-0

S-Adenosylhomocysteine

Pureza: 98%

Peso molecular: 384.41g/mol

Ref: 54-OR1014905

S-(5''-Adenosyl)-L-homocysteine

CAS: 979-92-0

Fórmula: C₁₄H₂₀N₆O₅S

Pureza: (HPLC) ≥ 98.0%

Forma y color: White to almost white powder

Peso molecular: 384.41

Ref: 7W-GN9993

SAH

CAS: 979-92-0

SAH

Pureza: ≥98%

Peso molecular: 384.41g/mol

Ref: 54-BUP06704

SAH

CAS: 979-92-0

SAH (SAH (S-Adenosylhomocysteine)) is an inhibitor for the METTL3-METTL14 heterodimer complex (METTL3-14, IC50: 0.9 μM).

Fórmula: C₁₄H₂₀N₆O₅S

Pureza: 98.45% - >99.99%

Forma y color: Solid

Peso molecular: 384.41

Ref: TM-TQ0208

S-Adenosyl-L-Homocysteine-15N4

CAS: 979-92-0

Fórmula: C₁₄H₂₀N₂₁₅N₄O₅S

Peso molecular: 388.38

Ref: 4Z-C-7728

S-(5'-Adenosyl)-L-homocysteine-d4

Producto controlado

CAS: 979-92-0

Applications S-(5'-Adenosyl)-L-homocysteine-d4 is labelled S-(5'-Adenosyl)-L-homocysteine (A291500), a novel biomarker for predicting susceptibility of a subject to a mental or neurodegenerative disorder.
References Chamberlin, M., et al.: J. Clin. Invest., 98, 1021 (1996); Zoccolella, S., et al.: Neurology, 70, 222 (2008)

Fórmula: C₁₄D₄H₁₆N₆O₅S

Forma y color: Neat

Peso molecular: 388.44

Ref: TR-A291501

S-Adenosyl-L-Homocysteine

CAS: 979-92-0

Fórmula: C₁₄H₂₀N₆O₅S

Peso molecular: 384.41

Ref: ST-EA-CP-A88015

S-(5'-Adenosyl)-L-homocysteine dihydrate

CAS: 979-92-0

S-(5'-Adenosyl)-L-homocysteine dihydrate is the active form of homocysteine. It has been shown to inhibit the growth of HL-60 cells and induce apoptosis in these cells. S-(5'-Adenosyl)-L-homocysteine dihydrate binds to dsDNA as a methyltransferase inhibitor, which leads to DNA methylation and inhibits DNA binding. The inhibition of DNA binding prevents transcription, leading to cell death. This drug has also been shown to have an anti-atherosclerotic effect in a model system by inhibiting the adenosine receptor.

Fórmula: C₁₄H₂₀N₆O₅S•(H₂O)₂

Pureza: Min. 98 Area-%

Forma y color: Powder

Peso molecular: 420.44 g/mol

Ref: 3D-NA17223

S-(5′-deoxyadenosin-5′-yl)-L-Homocysteine

CAS: 979-92-0

Fórmula: C₁₄H₂₀N₆O₅S

Pureza: 97%

Peso molecular: 384.41

Ref: 10-F448169

S-(((2S,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl-2,3,4,5-13C4)methyl-13C)-L-homocysteine

CAS: 979-92-0

Fórmula: C₉₁₃C₅H₂₀N₆O₅S

Forma y color: Neat

Peso molecular: 389.37

Ref: TR-A291502

S-(5-Adenosyl)-L-Homocysteine extrapure, 99%

CAS: 979-92-0

Fórmula: C₁₄H₂₀N₆O₅S

Pureza: min.99%

Forma y color: White, Crystalline powder

Peso molecular: 384.41

Ref: SR-46600

S-(5'-Adenosyl)-L-homocysteine

CAS: 979-92-0

Fórmula: C₁₄H₂₀N₆O₅S

Forma y color: Neat

Peso molecular: 384.41

Ref: TR-A291500

S-(((2S,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl-13C5)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)-L-homocysteine

Producto controlado

CAS: 979-92-0

Fórmula: C₉₁₃C₅H₂₀N₆O₅S

Forma y color: Neat

Peso molecular: 389.37

Ref: TR-A291504

S-(((2S,3S,4R,5R)-5-(6-Amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl-13C)-L-homocysteine-13C4

Producto controlado

CAS: 979-92-0

Fórmula: C₉₁₃C₅H₂₀N₆O₅S

Forma y color: Neat

Peso molecular: 389.37

Ref: TR-A291507