CAS 98105-99-8

Sarafloxacina

Descripción:

Sarafloxacina es un antibiótico fluoroquinolona sintético que se utiliza principalmente en medicina veterinaria, particularmente para tratar infecciones bacterianas en ganado y aves de corral. Exhibe una actividad antibacteriana de amplio espectro contra bacterias tanto Gram-positivas como Gram-negativas al inhibir la girasa del ADN bacteriano y la topoisomerasa IV, enzimas críticas para la replicación y transcripción del ADN. Sarafloxacina se caracteriza por su estructura química, que incluye un núcleo bicíclico y un átomo de flúor que mejora su potencia y espectro de actividad. El compuesto se administra típicamente por vía oral y es conocido por su relativamente alta biodisponibilidad. Su farmacocinética implica una rápida absorción y distribución, con una vida media moderada, lo que permite regímenes de tratamiento efectivos. Sin embargo, el uso de Sarafloxacina ha suscitado preocupaciones sobre la resistencia a los antibióticos y su posible impacto en la salud humana, lo que ha llevado a un escrutinio regulatorio en algunas regiones. Al igual que con otros antibióticos, el uso apropiado es esencial para mitigar el desarrollo de cepas bacterianas resistentes.

Fórmula: C₂₀H₁₇F₂N₃O₃

InChI: InChI=1S/C20H17F2N3O3/c21-12-1-3-13(4-2-12)25-11-15(20(27)28)19(26)14-9-16(22)18(10-17(14)25)24-7-5-23-6-8-24/h1-4,9-11,23H,5-8H2,(H,27,28)

Clave InChI: InChIKey=XBHBWNFJWIASRO-UHFFFAOYSA-N

SMILES: O=C1C=2C(N(C=C1C(O)=O)C3=CC=C(F)C=C3)=CC(=C(F)C2)N4CCNCC4

Sinónimos:

• 3-Quinolinecarboxylic Acid, 6-Fluoro-1-(4-Fluorophenyl)-1,4-Dihydro-4-Oxo-7-(1-Piperazinyl)-
• 6-Fluoro-1-(4-Fluorophenyl)-4-Oxo-7-(Piperazin-1-Yl)-1,4-Dihydroquinoline-3-Carboxylic Acid
• 6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
• 98105-99-8
• A 56620
• Pd 121960
• Sarafloxacin

Sarafloxacin Hydrochloride

CAS: 91296-87-6, 98105-99-8

Fórmula: C₂₀H₁₇F₂N₃O₃·HCl

Pureza: >97.0%(HPLC)

Forma y color: White to Light yellow to Light orange powder to crystal

Peso molecular: 421.83

Ref: 3B-S0840

Sarafloxacin

CAS: 98105-99-8

Fórmula: C₂₀H₁₇F₂N₃O₃

Pureza: 98%

Forma y color: Solid

Peso molecular: 385.3641

Ref: IN-DA00H5SQ

Sarafloxacin

CAS: 98105-99-8

Sarafloxacin

Pureza: ≥95%

Peso molecular: 385.36g/mol

Ref: 54-BUP17109

Sarafloxacin

CAS: 98105-99-8

Fórmula: C₂₀H₁₇F₂N₃O₃

Peso molecular: 385.36

Ref: 7W-GP7127

Sarafloxacin

CAS: 98105-99-8

Applications Sarafloxacin is a quinolone antibiotic drug that was discontinued in 2001. Useful for biological studies and can be detected with colloidal gold test strips.
References Jia, F., et al.: Agric. Biotechnol., 8, 172 (2019)

Fórmula: C₂₀H₁₇F₂N₃O₃

Forma y color: Light Yellow

Peso molecular: 385.36

Ref: TR-S139503

Sarafloxacin

CAS: 98105-99-8

Sarafloxacin is an antimicrobial agent that belongs to the quinolone class. It has a chemical stability that allows for use in an injection solution, which may be useful for treating infectious diseases. Sarafloxacin has been shown to be active against human pathogens such as Haemophilus influenzae and Neisseria meningitides. This drug also shows activity against other human pathogens such as Streptococcus pneumoniae, Chlamydia pneumoniae, and Mycoplasma pneumoniae. Sarafloxacin inhibits bacterial growth by acting on DNA gyrase, a type II topoisomerase, and RNA polymerase. The fluorescence detector detects fluorescence emitted from sarafloxacin-treated cells in the presence of two different wavelengths of light. This method is used in conjunction with LC-MS/MS to identify the antibiotic’s molecular targets and determine its mechanism of action.

Fórmula: C₂₀H₁₇F₂N₃O₃

Pureza: Min. 97 Area-%

Forma y color: Powder

Peso molecular: 385.36 g/mol

Ref: 3D-FS38236

Sarafloxacin

CAS: 98105-99-8

Fórmula: C₂₀H₁₇F₂N₃O₃

Pureza: 98%

Peso molecular: 385.371

Ref: 10-F324699

Sarafloxacin

CAS: 98105-99-8

Sarafloxacin (A56620) has antibacterial activities against Gram-positive and Gram-negative bacteria.

Fórmula: C₂₀H₁₇F₂N₃O₃

Pureza: 98.07% - 98.94%

Forma y color: Solid

Peso molecular: 385.36

Ref: TM-T20774