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CAS 99294-94-7

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Acetato de teriparatida hidratado

Descripción:
Acetato de teriparatida hidratado es un péptido sintético que imita la acción de la hormona paratiroidea (PTH) y se utiliza principalmente en el tratamiento de la osteoporosis. Se caracteriza por su capacidad para estimular la formación ósea al promover la actividad de los osteoblastos, lo que lo hace particularmente efectivo para aumentar la densidad ósea y reducir el riesgo de fracturas en mujeres posmenopáusicas y en individuos con ciertos tipos de osteoporosis. La sustancia se administra típicamente por inyección subcutánea y es conocida por su vida media relativamente corta, lo que requiere dosis diarias. Acetato de teriparatida hidratado es un polvo blanco a blanco amarillento que es soluble en agua, y su formulación incluye acetato como contraión, lo que ayuda a estabilizar el péptido. La estructura molecular del compuesto consta de 34 aminoácidos y se clasifica como un fármaco biológico debido a su naturaleza peptídica. Al igual que con cualquier medicamento, es esencial considerar los posibles efectos secundarios, contraindicaciones y la necesidad de monitoreo durante el tratamiento.
Fórmula:C2H4O2·xH2O·xUnspecified
InChI:InChI=1/C181H291N55O51S2/c1-21-96(18)146(236-160(267)114(48-53-141(250)251)212-174(281)132(84-239)232-177(284)143(93(12)13)233-147(254)103(185)82-237)178(285)216-111(45-50-134(187)241)155(262)219-119(65-90(6)7)163(270)213-116(55-62-289-20)158(265)224-124(71-100-79-196-86-203-100)167(274)226-126(73-135(188)242)169(276)217-117(63-88(2)3)148(255)201-81-138(245)205-105(39-27-30-56-182)149(256)223-123(70-99-78-195-85-202-99)166(273)221-121(67-92(10)11)164(271)225-128(75-137(190)244)171(278)231-131(83-238)173(280)214-115(54-61-288-19)157(264)210-112(46-51-139(246)247)153(260)208-109(43-34-60-199-181(193)194)159(266)234-144(94(14)15)175(282)215-113(47-52-140(248)249)156(263)222-122(69-98-77-200-104-38-26-25-37-102(98)104)165(272)220-120(66-91(8)9)161(268)209-108(42-33-59-198-180(191)192)151(258)206-106(40-28-31-57-183)150(257)207-107(41-29-32-58-184)152(259)218-118(64-89(4)5)162(269)211-110(44-49-133(186)240)154(261)228-129(76-142(252)253)172(279)235-145(95(16)17)176(283)229-125(72-101-80-197-87-204-101)168(275)227-127(74-136(189)243)170(277)230-130(179(286)287)68-97-35-23-22-24-36-97/h22-26,35-38,77-80,85-96,103,105-132,143-146,200,237-239H,21,27-34,39-76,81-84,182-185H2,1-20H3,(H2,186,240)(H2,187,241)(H2,188,242)(H2,189,243)(H2,190,244)(H,195,202)(H,196,203)(H,197,204)(H,201,255)(H,205,245)(H,206,258)(H,207,257)(H,208,260)(H,209,268)(H,210,264)(H,211,269)(H,212,281)(H,213,270)(H,214,280)(H,215,282)(H,216,285)(H,217,276)(H,218,259)(H,219,262)(H,220,272)(H,221,273)(H,222,263)(H,223,256)(H,224,265)(H,225,271)(H,226,274)(H,227,275)(H,228,261)(H,229,283)(H,230,277)(H,231,278)(H,232,284)(H,233,254)(H,234,266)(H,235,279)(H,236,267)(H,246,247)(H,248,249)(H,250,251)(H,252,253)(H,286,287)(H4,191,192,198)(H4,193,194,199)
SMILES:CCC(C)C(C(=NC(CCC(=N)O)C(=NC(CC(C)C)C(=NC(CCSC)C(=NC(Cc1cnc[nH]1)C(=NC(CC(=N)O)C(=NC(CC(C)C)C(=NCC(=NC(CCCCN)C(=NC(Cc1cnc[nH]1)C(=NC(CC(C)C)C(=NC(CC(=N)O)C(=NC(CO)C(=NC(CCSC)C(=NC(CCC(=O)O)C(=NC(CCCNC(=N)N)C(=NC(C(C)C)C(=NC(CCC(=O)O)C(=NC(Cc1c[nH]c2ccccc12)C(=NC(CC(C)C)C(=NC(CCCNC(=N)N)C(=NC(CCCCN)C(=NC(CCCCN)C(=NC(CC(C)C)C(=NC(CCC(=N)O)C(=NC(CC(=O)O)C(=NC(C(C)C)C(=NC(Cc1cnc[nH]1)C(=NC(CC(=N)O)C(=NC(Cc1ccccc1)C(=O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)O)N=C(C(CCC(=O)O)N=C(C(CO)N=C(C(C(C)C)N=C(C(CO)N)O)O)O)O
Sinónimos:
  • <span class="text-smallcaps">L</smallcap>-Phenylalanine, <smallcap>L</smallcap>-seryl-<smallcap>L</smallcap>-valyl-<smallcap>L</smallcap>-seryl-<smallcap>L</smallcap>-α-glutamyl-<smallcap>L</smallcap>-isoleucyl-<smallcap>L</smallcap>-glutaminyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</smallcap>-methionyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</smallcap>-asparaginyl-<smallcap>L</smallcap>-leucylglycyl-<smallcap>L</smallcap>-lysyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</smallcap>-asparaginyl-<smallcap>L</smallcap>-seryl-<smallcap>L</smallcap>-methionyl-<smallcap>L</smallcap>-α-glutamyl-<smallcap>L</smallcap>-arginyl-<smallcap>L</smallcap>-valyl-<smallcap>L</smallcap>-α-glutamyl-<smallcap>L</smallcap>-tryptophyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</smallcap>-arginyl-<smallcap>L</smallcap>-lysyl-<smallcap>L</smallcap>-lysyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</smallcap>-glutaminyl-<smallcap>L</smallcap>-α-aspartyl-<smallcap>L</smallcap>-valyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</span>-asparaginyl-, acetate (salt), hydrate
  • <span class="text-smallcaps">L</smallcap>-Phenylalanine, <smallcap>L</smallcap>-seryl-<smallcap>L</smallcap>-valyl-<smallcap>L</smallcap>-seryl-<smallcap>L</smallcap>-α-glutamyl-<smallcap>L</smallcap>-isoleucyl-<smallcap>L</smallcap>-glutaminyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</smallcap>-methionyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</smallcap>-asparaginyl-<smallcap>L</smallcap>-leucylglycyl-<smallcap>L</smallcap>-lysyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</smallcap>-asparaginyl-<smallcap>L</smallcap>-seryl-<smallcap>L</smallcap>-methionyl-<smallcap>L</smallcap>-α-glutamyl-<smallcap>L</smallcap>-arginyl-<smallcap>L</smallcap>-valyl-<smallcap>L</smallcap>-α-glutamyl-<smallcap>L</smallcap>-tryptophyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</smallcap>-arginyl-<smallcap>L</smallcap>-lysyl-<smallcap>L</smallcap>-lysyl-<smallcap>L</smallcap>-leucyl-<smallcap>L</smallcap>-glutaminyl-<smallcap>L</smallcap>-α-aspartyl-<smallcap>L</smallcap>-valyl-<smallcap>L</smallcap>-histidyl-<smallcap>L</span>-asparaginyl-, acetate, hydrate (1:?:?)
  • Forteo
  • L-Phenylalanine, L-seryl-L-valyl-L-seryl-L-alpha-glutamyl-L-isoleucyl-L-glutaminyl-L-leucyl-L-methionyl-L-histidyl-L-asparaginyl-L-leucylglycyl-L-lysyl-L-histidyl-L-leucyl-L-asparaginyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-arginyl-L-valyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-arginyl-L-lysyl-L-lysyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-histidyl-L-asparaginyl-, acetate (salt)
  • L-Phenylalanine, L-seryl-L-valyl-L-seryl-L-alpha-glutamyl-L-isoleucyl-L-glutaminyl-L-leucyl-L-methionyl-L-histidyl-L-asparaginyl-L-leucylglycyl-L-lysyl-L-histidyl-L-leucyl-L-asparaginyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-arginyl-L-valyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-arginyl-L-lysyl-L-lysyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-histidyl-L-asparaginyl-, acetate (salt) hydrate
  • L-Seryl-L-valyl-L-seryl-L-alpha-glutamyl-L-isoleucyl-L-glutaminyl-L-leucyl-L-methionyl-L-histidyl-L-asparaginyl-L-leucylglycyl-L-lysyl-L-histidyl-L-leucyl-L-asparaginyl-L-seryl-L-methionyl-L-alpha-glutamyl-L-arginyl-L-valyl-L-alpha-glutamyl-L-tryptophyl-L-leucyl-L-arginyl-L-lysyl-L-lysyl-L-leucyl-L-glutaminyl-L-alpha-aspartyl-L-valyl-L-histidyl-L-asparaginyl-L-phenylalanine acetate (salt) hydrate
  • Parathar
  • Parathar acetate
  • Teribone
  • Teriparatide Acetate
  • Ver más sinónimos
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Pureza (%)
0
100
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0
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50
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90
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95
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100
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