CAS 99755-59-6

Rotigotina

Descripción:

Rotigotina es un agonista sintético de la dopamina utilizado principalmente en el tratamiento de la enfermedad de Parkinson y el síndrome de piernas inquietas. Actúa estimulando los receptores de dopamina en el cerebro, ayudando así a aliviar los síntomas asociados con la deficiencia de dopamina. La sustancia se caracteriza por su naturaleza lipofílica, lo que permite la administración transdérmica a través de una formulación en parche, proporcionando una liberación constante del medicamento a lo largo del tiempo. Rotigotina tiene una vida media relativamente corta, lo que requiere una administración continua para mantener niveles terapéuticos. Su estructura química incluye un centro quiral, que contribuye a su actividad farmacológica. Los efectos secundarios comunes pueden incluir náuseas, mareos y somnolencia, reflejando su actividad en el sistema nervioso central. Rotigotina se clasifica en la categoría de agonistas de la dopamina no ergolínicos, distinguiéndolo de otros tratamientos en la misma clase. Al igual que con cualquier medicamento, el monitoreo cuidadoso es esencial para gestionar los posibles efectos adversos y asegurar resultados terapéuticos óptimos.

Fórmula: C₁₉H₂₅NOS

InChI: InChI=1S/C19H25NOS/c1-2-11-20(12-10-17-6-4-13-22-17)16-8-9-18-15(14-16)5-3-7-19(18)21/h3-7,13,16,21H,2,8-12,14H2,1H3/t16-/m0/s1

Clave InChI: InChIKey=KFQYTPMOWPVWEJ-INIZCTEOSA-N

SMILES: OC1=C2C(C[C@@H](N(CCC3=CC=CS3)CCC)CC2)=CC=C1

Sinónimos:

• (-)-(S)-5,6,7,8-Tetrahydro-6-(propyl(2-(2-thienyl)ethyl)amino)-1-naphthol
• (-)-N 0437
• (6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol
• (6S)-6-[Propyl(2-thiophen-2-ylethyl)amino]-5,6,7,8-tetrahydronaphthalen-1-ol
• (6S)-6-{propyl[2-(thiophen-2-yl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol
• (S)-(-)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol
• (S)-(-)-Rotigotine
• (S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-naphth-1-ol
• (S)-6-[Propyl[2-(thiophen-2-yl)ethyl]amino]-5,6,7,8-tetrahydronaphthalen-1-ol
• 1-Naphthalenol 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-, (6S)-
• 1-Naphthalenol, 5,6,7,8-tetrahydro-6-(propyl(2-(2-thienyl)ethyl)amino)-
• 1-Naphthalenol, 5,6,7,8-tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-, (S)-
• 2-(N-n-Propyl-N-2-thienylethylamino)-5-hydroxytetralin
• 5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol
• 6-(Propyl(2-(2-thienyl)ethyl)amino)-5,6,7,8-tetrahydro-1-naphthalenol
• 6-{Propyl[2-(Thiophen-2-Yl)Ethyl]Amino}-5,6,7,8-Tetrahydronaphthalen-1-Ol
• Leganto
• N 0923
• Neupro

Rotigotine impurity standard

CAS: 99755-59-6

Rotigotine impurity standard

Forma y color: White

Ref: 47-1243

Rotigotine

CAS: 99755-59-6

Rotigotine

Fórmula: C₁₉H₂₅NOS

Pureza: 99.6%

Forma y color: White

Peso molecular: 315.16569

Ref: 47-1242

ROTIGOTINE CRS

CAS: 99755-59-6

ROTIGOTINE CRS

Ref: 41-Y0002010

Rotigotine ((S)-6-{Propyl[2-(thiophen-2-yl)ethyl]amino}-5,6,7,8-tetrahydronaphthalen-1-ol)

CAS: 99755-59-6

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Fórmula: C₁₉H₂₅NOS

Forma y color: White Beige Powder

Peso molecular: 315.16569

Ref: 45-1606060

(6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol

CAS: 99755-59-6

Fórmula: C₁₉H₂₅NOS

Pureza: 99%

Forma y color: Solid

Peso molecular: 315.4729

Ref: IN-DA0039YJ

Rotigotine-

CAS: 99755-59-6

Rotigotine-

Pureza: ≥98%

Peso molecular: 315.47g/mol

Ref: 54-BUP15521

Rotigotine

CAS: 99755-59-6

Rotigotine

Pureza: 99%

Peso molecular: 315.47g/mol

Ref: 54-OR1023747

Rotigotine

CAS: 99755-59-6

Fórmula: C₁₉H₂₅NOS

Forma y color: Neat

Peso molecular: 315.47

Ref: 86-MM1403.00

Rotigotine-

CAS: 99755-59-6

Rotigotine (N-0923) is a non-ergot dopamine receptor agonist used in the therapy of Parkinson disease and restless leg syndrome.

Fórmula: C₁₉H₂₅NOS

Pureza: 98.08% - 99.59%

Forma y color: Solid

Peso molecular: 315.47

Ref: TM-T6647

(6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol

Producto controlado

CAS: 99755-59-6

(6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol is a potent and selective dopamine receptor agonist. It acts by binding to the dopamine receptors in the brain. This binding stimulates the release of dopamine and prevents it from being reabsorbed into the neurons, which in turn increases levels of extracellular dopamine in the synapse. (6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol has been shown to have antidepressant effects in animal models of depression. It also has a long half life and can be administered as a transdermal patch for prolonged relief from depression symptoms.

Fórmula: C₁₉H₂₅NOS

Pureza: Min. 95%

Forma y color: White Off-White Powder

Peso molecular: 315.47 g/mol

Ref: 3D-FT76640

Rotigotine

CAS: 99755-59-6

Fórmula: C₁₉H₂₅NOS

Pureza: >98.0%(T)(HPLC)

Forma y color: White to Almost white powder to crystal

Peso molecular: 315.48

Ref: 3B-R0220

Rotigotine

CAS: 99755-59-6

Fórmula: C₁₉H₂₅NOS

Pureza: 99%

Peso molecular: 315.166

Ref: 10-F513052

Rotigotine

CAS: 99755-59-6

Forma y color: Neat

Ref: 61-FOR1403.00