CAS 998-06-1

1,2-Dilinoleoil-sn-glicero-3-fosfocolina

Descripción:

1,2-Dilinoleoil-sn-glicero-3-fosfocolina, comúnmente conocido como DLPC, es un fosfolípido que juega un papel significativo en las membranas celulares y las bicapas lipídicas. Se caracteriza por sus dos cadenas de ácidos grasos linoleoyl, que contribuyen a su fluidez y flexibilidad, lo que lo convierte en un componente importante en la dinámica de membranas. La molécula presenta un esqueleto de glicerol, un grupo fosfato y un grupo cabeza de colina, que le confiere propiedades anfifílicas, permitiéndole interactuar tanto con entornos hidrofílicos como hidrofóbicos. El DLPC se utiliza a menudo en estudios biofísicos y sistemas de liberación de fármacos debido a su capacidad para formar liposomas y micelas. Sus propiedades estructurales le permiten estabilizar estructuras de membrana y facilitar la incorporación de otras moléculas, como fármacos o proteínas, mejorando su biodisponibilidad. Además, el DLPC se utiliza en diversas aplicaciones de investigación, incluidos estudios sobre la permeabilidad de membranas y el comportamiento de las bicapas lipídicas bajo diferentes condiciones. En general, sus características únicas lo convierten en una sustancia valiosa tanto en contextos biológicos como farmacéuticos.

Fórmula: C₄₄H₈₀NO₈P

InChI: InChI=1S/C44H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h14-17,20-23,42H,6-13,18-19,24-41H2,1-5H3/b16-14-,17-15-,22-20-,23-21-/t42-/m1/s1

Clave InChI: InChIKey=FVXDQWZBHIXIEJ-LNDKUQBDSA-N

SMILES: [C@H](OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)(COP(OCC[N+](C)(C)C)(=O)[O-])COC(CCCCCCC/C=C\C/C=C\CCCCC)=O

Sinónimos:

• (1,2-Dilinoleoyl)-3-lecithin
• (2R)-2,3-bis[(9Z,12Z)-octadeca-9,12-dienoyloxy]propyl 2-(trimethylammonio)ethyl phosphate
• (R-(All-Z))-(4-oxido-10-oxo-7-((1-oxooctadeca-9,12-dienyl)oxy)-3,5,9-trioxa-4-phosphaheptacosa-18,21-dienyl)trimethylammonium 4-oxide
• 1,2-Dilinoleoyl-sn-3-glycerophosphorylcholine
• 1,2-Dilinoleoyl-sn-glycero-3-phosphatidylcholine
• 1,2-Dilinoleoyl-sn-glycero-3-phosphocholine
• 1,2-Dilinoleoyl-sn-glycerol-3-phosphocholine
• 1,2-Dilinoleoylphosphocholine
• 1-Linoleoyl-2-linoleoyl-sn-glycero-3-phosphorylcholine
• 3,5,9-Trioxa-4-phosphaheptacosa-18,21-dien-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxo-9,12-octadecadienyl)oxy]-, hydroxide, inner salt, 4-oxide, [R-(all-Z)]-
• 3,5,9-Trioxa-4-phosphaheptacosa-18,21-dien-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxo-9,12-octadecadienyl)oxy]-, inner salt, 4-oxide, [R-(all-Z)]-
• 3,5,9-Trioxa-4-phosphaheptacosa-18,21-dien-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[[(9Z,12Z)-1-oxo-9,12-octadecadien-1-yl]oxy]-, inner salt, 4-oxide, (7R,18Z,21Z)-
• 3,5,9-Trioxa-4-phosphaheptacosa-18,21-dien-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[[(9Z,12Z)-1-oxo-9,12-octadecadienyl]oxy]-, inner salt, 4-oxide, (7R,18Z,21Z)-
• 49: PN: WO2017201317 SEQID: 122 claimed RNA
• <span class="text-smallcaps">L</span>-(+)-α-(α′,β-Dilinoleoyl)-glycerylphosphorylcholine
• <span class="text-smallcaps">L</span>-Dilinoleoyllecithin
• <span class="text-smallcaps">L</span>-α-Dilinoleoyl phosphatidylcholine
• Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-dilinolein, <span class="text-smallcaps">L</span>-(+)-
• DLiPC
• Linolein, 1,2-di-, dihydrogen phosphate, monoester with choline hydroxide, inner salt, <span class="text-smallcaps">L</span>-(+)-
• Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-dilinolein, L-(+)-

1,2-DILINOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

CAS: 998-06-1

Fórmula: C₄₄H₈₀NO₈P

Pureza: 98%

Forma y color: Solid

Peso molecular: 782.0817

Ref: IN-DA003W1P

1,2-Dilinoleoyl-sn-glycero-3-phosphocholine

CAS: 998-06-1

1,2-Dilinoleoyl-sn-glycero-3-phosphocholine

Forma y color: Solid

Peso molecular: 782.08g/mol

Ref: 54-BIL6001

1,2-Dilinoleoyl-sn-Glycero-3-Phosphatidylcholine

CAS: 998-06-1

Fórmula: C44H80NO8P

Pureza: >98%

Forma y color: Solid

Peso molecular: 782.08

Ref: 48-37-1802

(R)-2,3-Bis((9Z,12Z)-octadeca-9,12-dienoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate

CAS: 998-06-1

Pureza: ≥98%

Peso molecular: 782.0969849

Ref: 10-F791285

L-Dilinoleoyllecithin

Producto controlado

CAS: 998-06-1

Fórmula: C₄₄H₈₀NO₈P

Forma y color: Neat

Peso molecular: 782.082

Ref: TR-D561175

1,2-Dilinoleoyl-sn-glycero-3-phosphocholine

CAS: 998-06-1

1,2-Dilinoleoyl-sn-glycero-3-phosphocholine (DLPC) is a phospholipid that is used in the treatment of insulin resistance and inflammation. DLPC is a stable molecule that exhibits intermolecular hydrogen bonding and has been shown to be effective against inflammatory diseases. DLPC has been used as a liposomal formulation for the treatment of type 2 diabetes by improving insulin sensitivity, which may be due to its ability to inhibit proinflammatory cytokines such as tumor necrosis factor alpha (TNFα). It also binds to the receptor α, which are G protein coupled receptors present on cells involved in inflammatory responses. The binding of DLPC to these receptors leads to increased insulin sensitivity by inhibiting TNFα production.

Fórmula: C₄₄H₈₀NO₈P

Pureza: Min. 95%

Peso molecular: 782.08 g/mol

Ref: 3D-FD42822

L-Dilinoleoyllecithin

CAS: 998-06-1

L-Dilinoleoyllecithin is phosphatidylcholine. It is a glycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site.

Fórmula: C₄₄H₈₀NO₈P

Forma y color: Solid

Peso molecular: 782.08

Ref: TM-T24393