Canal de iones
Los canales iónicos son proteínas especializadas que forman poros en las membranas celulares, permitiendo el paso selectivo de iones como sodio, potasio, calcio y cloruro. Estos canales desempeñan un papel crucial en varios procesos fisiológicos, incluyendo la transmisión de impulsos nerviosos, la contracción muscular y la regulación de la homeostasis celular. Los canales iónicos son objetivos esenciales en la investigación de nuevos fármacos, particularmente en el tratamiento de trastornos neurológicos, enfermedades cardiovasculares y el manejo del dolor. En CymitQuimica, ofrecemos una amplia gama de proteínas de canales iónicos de alta calidad y reactivos relacionados para apoyar sus proyectos de investigación y desarrollo de medicamentos.
Se han encontrado 107 productos de "Canal de iones"
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Nicorandil - Bio-X ™
CAS:<p>Nicorandil is an ATP-dependent potassium channel activator. It activates mitochondrial ATP-dependent potassium (KATP) channels and inhibits the TLR4/MyD88/NF-κB/NLRP3 pathway, which reduces myocardial infarction-induced pyroptosis. Pyroptosis is an inflammatory cell death process that regulates cardiomyocyte loss after myocardial infarction. These findings suggest that nicorandil may be a potential therapy for ischemic heart disease due to its cardioprotective effects.</p>Fórmula:C8H9N3O4Pureza:(%) Min. 95%Forma y color:PowderPeso molecular:211.17 g/molBarnidipine hydrochloride
CAS:<p>Calcium channel blocker</p>Fórmula:C27H30ClN3O6Pureza:Min. 95%Forma y color:PowderPeso molecular:528 g/molVarenicline tartrate
CAS:<p>Partial agonist of α4β2 nicotinic receptors; acetylcholine receptor α7 agonist</p>Fórmula:C13H13N3·C4H6O6Pureza:Min. 95%Forma y color:White PowderPeso molecular:361.35 g/molFelodipine - Bio-X ™
CAS:<p>Felodipine is a calcium channel blocker and a member of the 1,4-dihydropyridine class of calcium channel blockers that is used to treat high blood pressure and related conditions. Felodipine increases the level of natriuretic peptide in the blood and reduces levels of infectious diseases such as influenza A virus and respiratory syncytial virus (RSV).<br>Felodipine is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.</p>Fórmula:C18H19Cl2NO4Pureza:Min. 95%Forma y color:PowderPeso molecular:384.25 g/molAloe-emodin - Bio-X ™
CAS:<p>Aloe-emodin is an anthraquinone derivative that is found in the aloe plant. It has a strong stimulant laxative action. Aloe-emodin may be useful in the treatment of cancer, as it inhibits cell proliferation by inducing apoptosis.</p>Fórmula:C15H10O5Pureza:Min. 95%Forma y color:PowderPeso molecular:270.24 g/molPiracetam - Bio-X ™
CAS:Producto controlado<p>Piracetam is a nootropic drug that is used for the treatment of sickle cell disease, alcohol dependence and as a cognitive enhancer. This drug is a cyclic derivative of GABA and has neuroprotective and anticonvulsant properties. Piracetam has been said to improve neuronal plasticity.</p>Fórmula:C6H10N2O2Pureza:Min. 95%Forma y color:PowderPeso molecular:142.16 g/molKainic acid monohydrate
CAS:<p>Agonist of kainate receptors, a subclass of ionotropic glutamate receptors with neuroexcitatory action. At high concentrations, it can induce seizures and act as neurotoxin, causing neuron death due to overstimulation.</p>Fórmula:C10H15NO4·H2OPureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:231.25 g/molAmbroxol HCl - Bio-X ™
CAS:<p>Ambroxol is a secretolytic agent that is used in the treatment of respiratory diseases and chronic coughs. Ambroxol has been shown to inhibit the NO-dependent activation of soluble guanylate cyclase so that the airway is not inflamed or its functions are not disturbed. Also, excessive mucus secretion is suppressed which as a result lowers the phlegm viscosity.</p>Fórmula:C13H18Br2N2O•HClPureza:Min. 95%Forma y color:PowderPeso molecular:414.56 g/molCilnidipine - Bio-X ™
CAS:<p>Clinidipine is a dihydropyridine calcium channel blocker that is used to treat hypertension. This drug acts on L-type calcium channels of blood vessels by blocking calcium and suppressing the contraction of blood vessels, thereby reducing blood pressure. . Cilnidipine also shows activity against N-type calcium channels.</p>Fórmula:C27H28N2O7Pureza:Min. 95%Forma y color:PowderPeso molecular:492.52 g/molNifedipine - Bio-X ™
CAS:<p>Nifedipine is a dihydropyridine calcium channel blocker that is used to manage several subtypes of angina pectoris and hypertension. This drug blocks L-type voltage gated calcium channels in order for blood pressure to be reduced and an increase in oxygen supply to the heart.</p>Fórmula:C17H18N2O6Pureza:Min. 95%Forma y color:PowderPeso molecular:346.33 g/molLamotrigine - Bio-X ™
CAS:Producto controlado<p>Lamotrigine is an antiepileptic phenyltriazine drug that is used to treat epilepsy and as a mood stabilizer in bipolar disorder. Although, this drug’s action is not fully well understood it is similar to carbamazepine which involves inhibiting voltage-sensitive sodium channels. Lamotrigine blocks voltage-sensitive sodium channels, which reduces neuronal excitability by blocking action potentials.</p>Fórmula:C9H7Cl2N5Pureza:Min. 95%Forma y color:PowderPeso molecular:256.09 g/molPF 06372865
CAS:<p>Positive allosteric modulator of GABA(A) receptor</p>Fórmula:C22H21FN4O3SPureza:Min. 95%Forma y color:PowderPeso molecular:440.49 g/molAmantadine hydrochloride - Bio-X ™
CAS:Producto controlado<p>Amantadine is an antiviral drug that is used to treat dyskinesia in patients with Parkinson’s disease. This drug’s mechanism is not fully understood however it is said to aid in releasing dopamine from the nerve ending in brain cells. Amantadine is also an NDMA antagonist.</p>Fórmula:C10H17N•HClPureza:Min. 95%Forma y color:PowderPeso molecular:187.71 g/molIsradipine
CAS:<p>L-type calcium channel blocker</p>Fórmula:C19H21N3O5Pureza:Min. 95%Forma y color:Yellow PowderPeso molecular:371.39 g/molIcilin - Bio-X ™
CAS:<p>Icilin is a transient receptor potential M8 (TRPM8) agonist drug that is used for the treatment of pruritis. This drug has shown to be effective in producing an extreme cold sensation in both human and animal models. It is used in research for studying TRP channels.</p>Fórmula:C16H13N3O4Pureza:Min. 95%Forma y color:PowderPeso molecular:311.29 g/molPrilocaine HCl - Bio-X ™
CAS:<p>Prilocaine is a drug used as a local anaesthetic in dental procedures. It has been shown to reduce the incidence of pain caused. This drug is also a sodium channel blocker that blocks the influx of sodium into cells.</p>Fórmula:C13H20N2O•HClPureza:Min. 95%Forma y color:PowderPeso molecular:256.77 g/molRepaglinide - Bio-X ™
CAS:<p>Repaglinide is an antihyperglycemic drug that is used for the improvement of glycemic control in diabetes. This drug acts on the beta cells of the pancreas and binds to specific receptors on the beta cells known as ATP-sensitive potassium channels. As a result, this promotes insulin secretion from beta cells.</p>Fórmula:C27H36N2O4Pureza:Min. 95%Forma y color:PowderPeso molecular:452.59 g/molVinpocetin - Bio-X ™
CAS:<p>Vinpocetin or Vinpocetine is a synthetic derivative of a vinca alkaloid that is used to treat symptoms of cerebrovascular diseases such as stroke and dementia. It blocks sodium channels, reduces cellular calcium influx and has shown to have antioxidant activity. Studies have also suggested that vinpocetin can inhibit phosphodiesterase- 1 (PDE-1) in isolated rabbit aorta.</p>Fórmula:C22H26N2O2Pureza:Min. 95%Forma y color:PowderPeso molecular:350.45 g/molMinoxidil - Bio-X ™
CAS:<p>Minoxidil is an antihypertensive agent used for the treatment of resistant hypertension that has caused organ damage. This drug has vasodilatory properties and promotes the survival of human dermal papillary cells. Therefore, this drug is also used to treat alopecia.</p>Fórmula:C9H15N5OPureza:Min. 95%Forma y color:PowderPeso molecular:209.25 g/molRiluzole - Bio-X ™
CAS:<p>Riluzole is a glutamate antagonist that is used for the treatment of amyotrophic lateral sclerosis. This drug is also used as an anticonvulsant. Although a complete mechanism of action is unknown, it has an inhibitory effect on glutamate release and it inactivates voltage dependent sodium channels.</p>Fórmula:C8H5F3N2OSPureza:Min. 95%Forma y color:PowderPeso molecular:234.2 g/mol
