Syk
Los inhibidores de Syk (tirosina quinasa del bazo) son compuestos que se dirigen a Syk, una quinasa involucrada en la señalización de células inmunitarias y la regulación de la angiogénesis. Syk desempeña un papel en las respuestas inflamatorias que pueden contribuir a la angiogénesis tumoral. Inhibir Syk puede reducir la formación de vasos sanguíneos inducida por la inflamación en los tumores, lo que convierte a estos inhibidores en herramientas valiosas en la terapia contra el cáncer y la investigación sobre inflamación. En CymitQuimica, ofrecemos una amplia gama de inhibidores de Syk de alta calidad para apoyar su investigación en inmunología, oncología y angiogénesis.
Se han encontrado 38 productos de "Syk"
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Piceatannol
CAS:Fórmula:C14H12O4Pureza:>98.0%(HPLC)Forma y color:White to Light yellow to Light red powder to crystalPeso molecular:244.25Gusacitinib
CAS:<p>Gusacitinib (ASN-002) (ASN-002) is spleen tyrosine kinase (SYK) and janus kinase (JAK) inhibitor (IC50: 5-46 nM).</p>Fórmula:C24H28N8O2Pureza:98.06% - 99.94%Forma y color:SolidPeso molecular:460.53Adrenalone hydrochloride
CAS:<p>Adrenalone HCl: α1-adrenoceptor agonist, topical hemostatic, vasoconstrictor, prolongs local anesthesia.</p>Fórmula:C9H11NO3·HClPureza:99.94%Forma y color:SolidPeso molecular:217.651,3-Benzodioxole, 5-(2-nitroethenyl)-
CAS:Fórmula:C9H7NO4Pureza:98%Forma y color:SolidPeso molecular:193.1562Piceatannol
CAS:<p>Piceatannol (Astringenin) is a synthetic anti-inflammatory that blocks p56lck, syk kinases, and NF-κB, made from resveratrol.</p>Fórmula:C14H12O4Pureza:98.66% - 99.73%Forma y color:Light Tan To Yellow PowderPeso molecular:244.24Lanraplenib
CAS:<p>Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases.</p>Fórmula:C23H25N9OPureza:98.35%Forma y color:SolidPeso molecular:443.51,2-Benzenediol, 4-[(1E)-2-(3,5-dihydroxyphenyl)ethenyl]-
CAS:Fórmula:C14H12O4Pureza:97%Forma y color:SolidPeso molecular:244.2427Tyrosine Kinase Inhibitor Library
<p>A unique collection of 1016 tyrosine kinase inhibitors for high throughput screening and high content screening for drug discovery in tyrosine kinase related</p>Forma y color:Odour SolidSyk Kinase Peptide Substrate, Biotin labeled
<p>The compound, Biotin-labeled Syk Kinase Peptide Substrate, is a peptide substrate of Syk kinase that is labeled with biotin.</p>Fórmula:C76H108N18O24S1Forma y color:SolidPeso molecular:1689.9Cevidoplenib dimesylate
CAS:<p>Cevidoplenib dimesylate is an inhibitor of spleen tyrosine kinase (Syk), possessing anti-inflammatory and immunomodulating properties.</p>Fórmula:C27H35N7O9S2Pureza:98%Forma y color:SolidPeso molecular:665.74Syk-IN-7
<p>Syk-IN-7 (compound 17) acts as an inhibitor of spleen tyrosine kinase (SYK) [1].</p>Fórmula:C26H31N9O4Pureza:98%Forma y color:SolidPeso molecular:533.58Lanraplenib succinate
CAS:<p>Lanraplenib succinate is an oral SYK inhibitor (IC50=9.5 nM) that doesn't extend BT, targeting GPVI in platelets for inflammation treatment.</p>Fórmula:C58H68N18O14Forma y color:SolidPeso molecular:1241.294MNS
CAS:Fórmula:C9H7NO4Pureza:>98.0%(GC)Forma y color:Light yellow to Yellow to Green powder to crystalPeso molecular:193.16BAY 61-3606 dihydrochloride
CAS:<p>BAY 61-3606 dihydrochloride (BAY 61-3606) is a potent and selective inhibitor of Syk kinase (Ki = 7.5 nM).</p>Fórmula:C20H18N6O3·2HClPureza:99.46%Forma y color:SolidPeso molecular:463.32Fostamatinib
CAS:<p>Fostamatinib (R788)(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on Lyn.</p>Fórmula:C23H26FN6O9PPureza:93.08% - 99.38%Forma y color:SolidPeso molecular:580.46TAK-659 hydrochloride
CAS:<p>TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM.</p>Fórmula:C17H22ClFN6OPureza:99.28% - 99.82%Forma y color:SolidPeso molecular:380.85Flavanomarein
CAS:<p>Flavanomarein: Antioxidant with radical scavenging, lipid peroxidation inhibition, and lipid-lowering in HepG2 cells.</p>Fórmula:C21H22O11Pureza:98.63% - 99.54%Forma y color:SolidPeso molecular:450.39PRT-060318
CAS:<p>PRT-060318 (P142-76) is a novel selective inhibitor of the Syk tyrosine kinase, as an approach to HIT treatment.</p>Fórmula:C18H24N6OPureza:99.98%Forma y color:SolidPeso molecular:340.42PRT062607 hydrochloride
CAS:<p>PRT062607 hydrochloride (P505-15 Hydrochloride) is a selective inhibitor of Syk. PRT062607 displays at least 80-fold selectivity for Syk over other kinases.</p>Fórmula:C19H23N9O·HClPureza:97.7% - 99.81%Forma y color:SolidPeso molecular:429.91BAY 61-3606
CAS:<p>BAY 61-3606 (Syk inhibitor IV) is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibiting</p>Fórmula:C20H18N6O3Pureza:98.72%Forma y color:SolidPeso molecular:390.4Cerdulatinib
CAS:<p>Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.</p>Fórmula:C20H27N7O3SPureza:98.74% - 99.49%Forma y color:SolidPeso molecular:445.54MNS
CAS:<p>MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.</p>Fórmula:C9H7NO4Pureza:98.53%Forma y color:Yellow PowderPeso molecular:193.16R112
CAS:<p>R112 ((E)-Elafibranor) is an ATP-competitive inhibitor of Syk kinase.</p>Fórmula:C16H13FN4O2Pureza:99.27% - 99.84%Forma y color:SolidPeso molecular:312.3Fostamatinib Disodium
CAS:<p>Fostamatinib Disodium (R788 Disodium) is an orally available Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities.</p>Fórmula:C23H24FN6O9P·2NaPureza:96.13% - 99.09%Forma y color:SolidPeso molecular:624.42Entospletinib
CAS:<p>Entospletinib (GS-9973) is a Syk inhibitor (IC50=7.7 nM) with selective, oral activity. High-Quality, Low-Cost!</p>Fórmula:C23H21N7OPureza:98.54% - 99.51%Forma y color:SolidPeso molecular:411.46R406
CAS:<p>R406 (R-406 besylate) is an effective Syk inhibitor (IC50: 41 nM) and shows no effects on Lyn.</p>Fórmula:C22H23FN6O5·C6H6O3SPureza:97.67% - 98.82%Forma y color:SolidPeso molecular:628.63R406 free base
CAS:<p>R406 free base (R406 (free base)) is a potent Syk inhibitor.</p>Fórmula:C22H23FN6O5Pureza:97.64% - 99.11%Forma y color:SolidPeso molecular:470.45Cerdulatinib hydrochloride
CAS:<p>Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 < 200 nM.</p>Fórmula:C20H28ClN7O3SPureza:99.85%Forma y color:SolidPeso molecular:482Syk Inhibitor II
CAS:<p>Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).</p>Fórmula:C14H15F3N6OPureza:97.63%Forma y color:SolidPeso molecular:340.3ER-27319
CAS:<p>ER-27319, an acridone derivative, serves as a potent and selective inhibitor of spleen tyrosine kinase (SYK), effectively impeding both the tyrosine</p>Fórmula:C20H22N2O5Pureza:98%Forma y color:SolidPeso molecular:370.4Sovleplenib
CAS:<p>Sovleplenib (HMPL-523), oral SYK inhibitor, IC50 25 nM, targets tumors & ITP studies.</p>Fórmula:C24H30N6O3SPureza:99.71%Forma y color:SolidPeso molecular:482.6Syk-IN-3
CAS:<p>Syk-IN-3 is a Syk inhibitor with potential anti-inflammatory and anticancer activity and can be used to study immune dysregulation.</p>Fórmula:C24H28N4O3SPureza:97.29% - >99.99%Forma y color:SolidPeso molecular:452.57RO9021
CAS:<p>RO9021 is an orally bioavailable, novel ATP-competitive SYK inhibitor (average IC50: 5.6 nM).</p>Fórmula:C18H25N7OPureza:97.19%Forma y color:SolidPeso molecular:355.44TC-S 7003
CAS:<p>TC-S 7003 (Lck Inhibitor) is a Lck inhibitor with anti-inflammatory activity that inhibits T-cell proliferation and can be used to study arthritis.</p>Fórmula:C31H30N8OPureza:99.74%Forma y color:SolidPeso molecular:530.62Lanraplenib monosuccinate
CAS:<p>Lanraplenib monosuccinate inhibits SYK activity in platelets via the glycoprotein VI (GPVI) receptor without prolonging bleeding time (BT) in monkeys or humans.</p>Fórmula:C27H31N9O5Pureza:98%Forma y color:SolidPeso molecular:561.59OXSI-2
CAS:<p>OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM.</p>Fórmula:C18H15N3O3SPureza:98%Forma y color:Dark Orange SolidPeso molecular:353.39MK-8457
CAS:<p>MK-8457 is a dual inhibitor of SYK and ZAP70, valuable for rheumatoid arthritis research [1].</p>Fórmula:C24H25F3N4O3SForma y color:SolidPeso molecular:506.54Syk-IN-8
CAS:<p>Syk-IN-8 (compound 19q) functions as a Syk inhibitor with demonstrated antiproliferative effects on a variety of hematological tumor cells.</p>Fórmula:C23H26N10Pureza:98%Forma y color:SolidPeso molecular:442.52
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