Serina / treonina quinasa
Los inhibidores de quinasas de serina/treonina son compuestos que se dirigen a las enzimas responsables de la fosforilación de residuos de serina y treonina en proteínas, las cuales desempeñan un papel crucial en la regulación de la apoptosis y otros procesos celulares. Estas quinasas están involucradas en vías de señalización que controlan el crecimiento, la división y la muerte celular programada. Inhibir quinasas específicas de serina/treonina puede alterar el equilibrio entre la supervivencia celular y la apoptosis, lo que convierte a estos inhibidores en herramientas esenciales en la investigación del cáncer y otras áreas de la biología celular. En CymitQuimica, ofrecemos una selección completa de inhibidores de quinasas de serina/treonina de alta calidad para apoyar su investigación en apoptosis, transducción de señales y mecanismos de enfermedades.
Se han encontrado 17 productos de "Serina / treonina quinasa"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
BMT-124110 Formate
BMT-124110 Formate is a selective AAK1 inhibitor (IC50: 0.9 nM) with anti-injury sensory activity.BMT-124110 Formate inhibits the BMP-2-inducible protein kinase
Fórmula:C22H20N2O2Pureza:99.52%Forma y color:SoildPeso molecular:344.41CRA-2059
CAS:CRA-2059 is a selective and reversible inhibitor of human tryptase beta, exhibiting a Ki value of 620 pM against recombinant human tryptase beta (rHTβ).Fórmula:C34H46N12O8Pureza:97.68% - 99.29%Forma y color:SolidPeso molecular:750.82TLK1-IN-1
TLK1-IN-1 (Compound 5n) is a TLK1 inhibitor with an IC50 of 7.2 μM for TLK1B and a GI50 of 2.7 μM for LNCaP cells. It induces DNA damage and apoptosis (Apoptosis) in cancer cells and is applicable in prostate cancer research.Fórmula:C24H23BrClN5O3Forma y color:SoildPeso molecular:544.831,8-Diazanaphthalene
CAS:1,8-Diazanaphthalene inhibits Protein Kinase B with a binding constant Ka=407 μM.Fórmula:C8H6N2Peso molecular:130.15PKD-IN-1
CAS:CRT0066101 is an inhibitor of PKD.Fórmula:C18H19ClN4OPureza:98%Forma y color:SolidPeso molecular:342.82GAK inhibitor 49
CAS:GAK inhibitor 49 is a highly selective and ATP-competitive cyclin G associated kinase (GAK) inhibitor (IC50: 56 nM; Ki: 0.54 nM ).Fórmula:C20H22N2O5Pureza:98.71%Forma y color:SolidPeso molecular:370.4Ref: TM-T8535
1mg54,00€5mg111,00€10mg177,00€25mg299,00€50mg430,00€100mg587,00€200mg792,00€1mL*10mM (DMSO)128,00€CID755673
CAS:CID755673 inhibits PKD (IC50: 182 nM), with selectivity over PLK1, AKT, CAMKIIα, CAK, PKC.Fórmula:C12H11NO3Pureza:97.68% - 99.84%Forma y color:SolidPeso molecular:217.221-Naphthyl PP1
CAS:1-Naphthyl PP1 (1-NA-PP 1) is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively)Fórmula:C19H19N5Pureza:99.85%Forma y color:White Cyrstalline SolidPeso molecular:317.39kb NB 142-70
CAS:kb NB 142-70 is a selective protein kinase D (PKD) inhibitor (IC50 values are 28.3, 58.7 and 53.2 nM for PKD1, 2 and 3 respectively).Fórmula:C11H9NO2S2Pureza:98.15% - ≥95%Forma y color:SolidPeso molecular:251.32SGC-GAK-1
CAS:SGC-GAK-1 is a selective cyclin G-associated kinase (GAK) inhibitor (Ki: 3.1 nM).
Fórmula:C18H17BrN2O3Pureza:99.85%Forma y color:SolidPeso molecular:389.24MLCK inhibitor peptide 18 acetate
MLCK inhibitor peptide 18 acetate: Selective (IC50=50nM), 4000x more than CaM kinase II. Does not block PKA. Cell-permeable.Fórmula:C62H109N23O13Pureza:99.57%Forma y color:SolidPeso molecular:1384.67SRPIN340
CAS:SRPIN340 (SRPK inhibitor), a serine/arginine-rich protein kinase (SRPK)-specific inhibitor, is potent for SRPK1 (IC50 = 0.89 uM).Fórmula:C18H18F3N3OPureza:99.79% - 99.96%Forma y color:SolidPeso molecular:349.35Ref: TM-T1954
2mg44,00€5mg65,00€10mg100,00€25mg177,00€50mg324,00€100mg421,00€500mg945,00€1mL*10mM (DMSO)71,00€CID 2011756
CAS:CID 2011756 is an ATP-competitive and specific PKD1 inhibitor.Fórmula:C22H21ClN2O3Pureza:98.15% - ≥95%Forma y color:SolidPeso molecular:396.87SPHINX31
CAS:SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).Fórmula:C27H24F3N5O2Pureza:99.3% - 99.87%Forma y color:SolidPeso molecular:507.51Ref: TM-T5194
1mg40,00€5mg84,00€10mg97,00€25mg180,00€50mg269,00€100mg430,00€500mg998,00€1mL*10mM (DMSO)87,00€SRPKIN-1
CAS:SRPKIN-1 is a covalent and irreversible inhibitor of SRPK1/2 (IC50s: 35.6 and 98 nM, respectively).Fórmula:C27H21FN2O3SPureza:98%Forma y color:SolidPeso molecular:472.53Anti-neuroinflammation agent 3
CAS:Compound A.10.3 (Anti-neuroinflammation agent 3) exhibits inhibitory activity against various Ser/Thr kinases or receptor/non-receptor tyrosine kinases.Fórmula:C22H23FN6O2Peso molecular:422.455Protein kinase inhibitor 14
CAS:Protein kinase inhibitor 14 (Compound 13) exhibits inhibitory effects on various serine/threonine kinases and receptor/non-receptor tyrosine kinases.Fórmula:C22H22F2N6OForma y color:SolidPeso molecular:424.447
