Serina / treonina quinasa
Los inhibidores de quinasas de serina/treonina son compuestos que se dirigen a las enzimas responsables de la fosforilación de residuos de serina y treonina en proteínas, las cuales desempeñan un papel crucial en la regulación de la apoptosis y otros procesos celulares. Estas quinasas están involucradas en vías de señalización que controlan el crecimiento, la división y la muerte celular programada. Inhibir quinasas específicas de serina/treonina puede alterar el equilibrio entre la supervivencia celular y la apoptosis, lo que convierte a estos inhibidores en herramientas esenciales en la investigación del cáncer y otras áreas de la biología celular. En CymitQuimica, ofrecemos una selección completa de inhibidores de quinasas de serina/treonina de alta calidad para apoyar su investigación en apoptosis, transducción de señales y mecanismos de enfermedades.
Se han encontrado 19 productos para "Serina / treonina quinasa".
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CRA-2059
CAS:CRA-2059 is a selective and reversible inhibitor of human tryptase beta, exhibiting a Ki value of 620 pM against recombinant human tryptase beta (rHTβ).Fórmula:C34H46N12O8Pureza:97.68% - 99.29%Forma y color:White SolidPeso molecular:750.821,8-Diazanaphthalene
CAS:1,8-Diazanaphthalene inhibits Protein Kinase B with a binding constant Ka=407 μM.Fórmula:C8H6N2Forma y color:SolidPeso molecular:130.15TLK1-IN-1
TLK1-IN-1 (Compound 5n) is a TLK1 inhibitor with an IC50 of 7.2 μM for TLK1B and a GI50 of 2.7 μM for LNCaP cells. It induces DNA damage and apoptosis (Apoptosis) in cancer cells and is applicable in prostate cancer research.Fórmula:C24H23BrClN5O3Forma y color:SolidPeso molecular:544.83Tilpisertib
CAS:Tilpisertib is a serine/threonine kinase inhibitor (WO2017007689).Fórmula:C33H33ClN8OForma y color:SolidPeso molecular:593.13PKD-IN-1
CAS:CRT0066101 is an inhibitor of PKD.Fórmula:C18H19ClN4OPureza:98%Forma y color:SolidPeso molecular:342.82kb NB 142-70
CAS:kb NB 142-70 is a selective protein kinase D (PKD) inhibitor (IC50 values are 28.3, 58.7 and 53.2 nM for PKD1, 2 and 3 respectively).Fórmula:C11H9NO2S2Pureza:98.01% - ≥95%Forma y color:SolidPeso molecular:251.321-Naphthyl PP1
CAS:1-Naphthyl PP1 (1-NA-PP 1) is a selective src inhibitor(v-Src and c-Fyn, c-Abl, CDK2 and CAMK II with IC50s of 1.0, 0.6, 0.6, 18 and 22 μM, respectively)Fórmula:C19H19N5Pureza:99.85%Forma y color:SolidPeso molecular:317.39MLCK inhibitor peptide 18 acetate
MLCK inhibitor peptide 18 acetate: Selective (IC50=50nM), 4000x more than CaM kinase II. Does not block PKA. Cell-permeable.Fórmula:C62H109N23O13Pureza:99.90%Forma y color:SolidPeso molecular:1384.67SRPIN340
CAS:SRPIN340 (SRPK inhibitor), a serine/arginine-rich protein kinase (SRPK)-specific inhibitor, is potent for SRPK1 (IC50 = 0.89 uM).Fórmula:C18H18F3N3OPureza:99.79% - 99.96%Forma y color:White SolidPeso molecular:349.35Ref: TM-T1954
2mg44,00€5mg65,00€1mL*10mM (DMSO)71,00€10mg100,00€25mg177,00€50mg324,00€100mg421,00€500mg945,00€CID 2011756
CAS:CID 2011756 is an ATP-competitive and specific PKD1 inhibitor.Fórmula:C22H21ClN2O3Pureza:98.15% - ≥95%Forma y color:SolidPeso molecular:396.87SPHINX31
CAS:SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1; IC50: 5.9 nM).Fórmula:C27H24F3N5O2Pureza:99.3% - 99.87%Forma y color:SolidPeso molecular:507.51Ref: TM-T5194
1mg38,00€5mg79,00€10mg92,00€1mL*10mM (DMSO)93,00€25mg170,00€50mg255,00€100mg408,00€500mg945,00€GAK inhibitor 49
CAS:GAK inhibitor 49 is a highly selective and ATP-competitive cyclin G associated kinase (GAK) inhibitor (IC50: 56 nM; Ki: 0.54 nM ).Fórmula:C20H22N2O5Pureza:98.71%Forma y color:SolidPeso molecular:370.4Ref: TM-T8535
1mg54,00€5mg111,00€1mL*10mM (DMSO)128,00€10mg177,00€25mg299,00€50mg430,00€100mg587,00€200mg792,00€CID755673
CAS:CID755673 inhibits PKD (IC50: 182 nM), with selectivity over PLK1, AKT, CAMKIIα, CAK, PKC.Fórmula:C12H11NO3Pureza:97.68% - 99.84%Forma y color:SolidPeso molecular:217.22SGC-GAK-1
CAS:SGC-GAK-1 is a selective cyclin G-associated kinase (GAK) inhibitor (Ki: 3.1 nM).Fórmula:C18H17BrN2O3Pureza:99.85%Forma y color:Yellow SolidPeso molecular:389.24SRPKIN-1
CAS:SRPKIN-1 is a covalent and irreversible inhibitor of SRPK1/2 (IC50s: 35.6 and 98 nM, respectively).Fórmula:C27H21FN2O3SPureza:98%Forma y color:SolidPeso molecular:472.53Anti-neuroinflammation agent 3
CAS:Compound A.10.3 (Anti-neuroinflammation agent 3) exhibits inhibitory activity against various Ser/Thr kinases or receptor/non-receptor tyrosine kinases.Fórmula:C22H23FN6O2Forma y color:SolidPeso molecular:422.455Protein kinase inhibitor 14
CAS:Protein kinase inhibitor 14 (Compound 13) exhibits inhibitory effects on various serine/threonine kinases and receptor/non-receptor tyrosine kinases.Fórmula:C22H22F2N6OForma y color:SolidPeso molecular:424.447MASTL-IN-3
CAS:MASTL-IN-3 (compound 60) is an effective MASTL inhibitor (pIC50 = 9.10 M) exhibiting antiproliferative activity.Fórmula:C17H17F2N9Pureza:99.57%Peso molecular:385.37Ofirnoflastum
CAS:Ofirnoflastum (Ofirnoflast) is a selective serine/threonine-protein kinase Nek7 inhibitor that exerts potent anti-inflammatory effects by suppressing Nek7-dependent NLRP3 inflammasome activation, reducing caspase-1 cleavage, IL-1β and IL-18 secretion, and pyroptotic cell death in vitro, while significantly attenuating cytokine production and tissue injury in animal models of acute and chronic inflammation, supporting its therapeutic potential in autoimmune and inflammatory diseases.Fórmula:C23H19F4N7O2Forma y color:SolidPeso molecular:501.44
