PD-1 / PD-L1

BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in …

Sulfamethoxypyridazine is a sulfanilamide antibacterial agent.

INCB086550 (example 24) is a PD-1/PD-L1 inhibitor, with an IC50 <= 10 nM.

PD-1/PD-L1-IN-9 is a potent and orally active inhibitor of PD-1/PD-L1 interaction, IC50 = 3.8 nM. …

Sintilimab (anti-PD-1, IBI 308) 是一种全人源 IgG4 单克隆抗体,可与 T 细胞表面的PD-1结合,阻断 PD-1/PD-配体 1 (PD-L1) 通路,并重新激活 T 细胞以杀死癌细胞。

Spartalizumab (anti-PD-1)是一种针对PD-1的人源IgG4抗体,抑制PD-L1和PD-L2与PD-1的结合。PDR001可与PD-1以高亲和力结合,抑制其生物活性；MW: 145.8 KD。

AUNP-12 acetate is a polypeptide inhibitor of PD-1 that is equivalent to PD-1 and PD-2 …

Camrelizumab (anti-PD-1)是一种针对PD-1的人源IgG4抗体,抑制PD-L1和PD-L2与PD-1的结合,具有抑制免疫检查点效果和抗肿瘤活性；MW: 146.3 KD。

PD-1/PD-L1-IN-NP19 is a PD-1/PD-L1 inhibitor, with an IC50 of 12.5 nM for human PD-1/PD-L1 interaction. …

PD-1-IN-22 is a potent programmed cell death-1 (PD-1)/programmed cell death-ligand 1 (PD-L1) interaction inhibitor(IC50 of …

eFT508 is a potent, highly selective MNK1 and MNK2 inhibitor with IC50 value of 1-2 …

BMS-8 is a novel inhibitor of the PD-1/PD-L1 interaction (IC50: 7.2 μM) by binding directly …

Atezolizumab anti-PD-L1) is a fully humanized IgG1 monoclonal antibody that blocks the interaction of PD-L1 …

PD1-PD-L1 inhibitor 1 (PD1-PD-L1-IN-1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. It also acts …

1. Fraxinellone significantly reduced weight loss and diarrhea in mice and alleviated the macroscopic and …

Nivolumab anti-PD-1) is a genetically engineered fully human immunoglobulin Ig) G4 monoclonal antibody directed against …

BMS-1166 is a potent PD-1/PD-L1 interaction inhibitor.

PDL-1 cpd 10 is a novel small molecule PD-L1 inhititor.

Pembrolizumab is a humanized monoclonal antibody inhibiting the PD-1 receptor and the first in the …

PD1-PDL1 inhibitor 2 is an inhibitor of the PD-1 (Programmed death- 1) /PD-Ll (Programmed death-ligand …

PD-1/PD-L1-IN-10 is an orally active PD-1/PD-L1 inhibitor (IC50 of 2.7 nM) with potent anticancer efficacy.

PD-1/PD-L1 inhibitor 2 is a small-molecule PD-1/PD-L1 interaction inhibitor (IC50: 18 nM). Biophysical studies demonstrate …

Avelumab is a fully human IgG1 anti-PD-L1 monoclonal antibody. Avelumab shows potential antibody-dependent cell-mediated cytotoxicity.

BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25 nM, in a homogenous time-resolved …

PD-1-IN-17 is an inhibitor of programmed cell death-1 (PD-1). PD-1-IN-17 inhibits 92% splenocyte proliferation at …