PD-1 / PD-L1
Os inibidores de PD-1/PD-L1 são inibidores de checkpoints imunológicos que bloqueiam a interação entre a proteína de morte celular programada 1 (PD-1) nas células T e seu ligante PD-L1 nas células cancerígenas. Essa interação normalmente suprime a resposta imunológica e permite que as células cancerígenas evitem a detecção imunológica. Ao inibir PD-1/PD-L1, esses inibidores aumentam a capacidade do sistema imunológico de reconhecer e destruir células cancerígenas, induzindo apoptose e regressão tumoral. Os inibidores de PD-1/PD-L1 são fundamentais na pesquisa em imunoterapia e no tratamento do câncer. Na CymitQuimica, oferecemos uma gama de inibidores de PD-1/PD-L1 de alta qualidade para apoiar sua pesquisa em imunooncologia, apoptose e terapia do câncer.
Se han encontrado 125 productos de "PD-1 / PD-L1"
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Penpulimab
CAS:<p>Penpulimab is a monoclonal antibody targeting PD-1 with antitumor activity, used in studies of pancreatic cancer.</p>Pureza:96.8% (SEC-HPLC) - 96.8% (SEC-HPLC)Forma y color:LiquidEzabenlimab
CAS:<p>Ezabenlimab (BI-754091) is an anti-PD-1 mAb, Kd 6 nM, blocks PD-1/PD-Ls, boosts T-cell IFN-γ, inhibits tumors in vivo.</p>Pureza:99.1% (SDS-PAGE); 96.9% (SEC-HPLC) - 99.1% (SDS-PAGE); 96.9% (SEC-HPLC)Forma y color:LiquidBudigalimab
CAS:<p>Budigalimab (ABBV 181) is a humanized monoclonal antibody targeting PD-1 with potential antitumor activity.</p>Pureza:97% (SDS-PAGE); 98.8% (SEC-HPLC) - 97% (SDS-PAGE); 98.8% (SEC-HPLC)Forma y color:LiquidAUNP-12 acetate
<p>AUNP-12 acetate is a polypeptide inhibitor of PD-1 that is equivalent to PD-1 and PD-2 in inhibiting lymphocyte proliferation and effector fuction, in addition</p>Fórmula:C144H230N40O50Pureza:95.07%Forma y color:SolidPeso molecular:3321.61Durvalumab
CAS:<p>Durvalumab is a humanized antibody for cancer, inhibiting PD-L1/PD-1 and CD80 interactions at very low concentrations.</p>Pureza:SDS-PAGE:97.2%;SEC-HPLC:95.3%Forma y color:LiquidPeso molecular:146.03 kDaBMS-1001 hydrochloride
CAS:<p>BMS-1001 hydrochloride is an orally active inhibitor of human PD-1/PD-L1 immune checkpoint with low-toxicity in cells.BMS-1001 alleviates the inhibitory effect</p>Fórmula:C35H35ClN2O7Pureza:97.36%Forma y color:SolidPeso molecular:631.11Dostarlimab
CAS:<p>Dostarlimab (TSR-042) is an immune checkpoint inhibitor targeting PD-1, blocking its interaction with its ligands PD-L1 and PD-L2.</p>Pureza:>95%Forma y color:LiquidZimberelimab
CAS:<p>Zimberelimab (GLS-010) is a humanized antibody targeting PD-1, with anticancer activity.</p>Pureza:95%Forma y color:LiquidSintilimab
CAS:<p>Sintilimab (IBI308), an IgG4 monoclonal antibody, blocks PD-1, enhancing T-cell anti-tumor response; treats Hodgkin's, lung, and esophageal cancers.</p>Pureza:> 95%Forma y color:LiquidPeso molecular:144.04 kDaSpartalizumab
CAS:<p>"Spartalizumab (PDR001), a humanized IgG4 monoclonal antibody, targets PD-1 to inhibit PD-L1/L2 interactions, useful in ATC research."</p>Pureza:SDS-PAGE:95.2%;SEC-HPLC:96.3%Forma y color:LiquidPeso molecular:145.74 kDaTislelizumab
CAS:<p>Tislelizumab, a PD-1 receptor monoclonal antibody, reduces Fcγ interaction and T cell clearance in advanced squamous NSCLC research.</p>Pureza:95.07%Forma y color:LiquidAnti-Mouse PD-1 (LALA-PG) Antibody (RMP1-14)
<p>Anti-MousePD-1(LALA-PG) Antibody (RMP1-14) is an IgG2a, κ antibody inhibitor derived from mice that targets and inhibits mouse PD-1.</p>Forma y color:Odour LiquidPD-1/PD-L1-IN-50
<p>Compound LG-12, known chemically as PD-1/PD-L1-IN-50, is an inhibitor of PD-1/PD-L1. It enhances the secretion of IFN-γ, promotes the activation of CD8+ T cells, and activates T cell-mediated anti-tumor immunity.</p>Forma y color:Odour SolidAnti-Mouse PD-1 Antibody (D265A) Antibody (RMP1-14)
<p>Anti-Mouse PD-1 Antibody (D265A) is an IgG2a, κ antibody inhibitor derived from mice, specifically targeting mouse PD-1.</p>Forma y color:Odour LiquidPM-8002
<p>PM-8002 is a bispecific antibody that targets PD-L1 and VEGF-A. It is applicable for research on solid tumors.</p>Forma y color:Odour LiquidEciskafusp alfa
CAS:<p>Eciskafusp alfa, a cis-targeted IL2v immunocytokine, acts on programmed cell death 1 (PDCD1, commonly known as PD-1), preferentially targeting antigen-specific</p>Pureza:98%Forma y color:SolidZeluvalimab
CAS:<p>Zeluvalimab (AMG-404) is a monoclonal antibody designed to target the PD-1 receptor, and is utilized in cancer research [1].</p>Forma y color:LiquidLorigerlimab
CAS:<p>Lorigerlimab (MGD019) is a bispecific IgG4 DART that blocks PD-1/CTLA-4, enhancing T-cells for mCRPC research.</p>Forma y color:LiquidSotiburafusp alfa
CAS:<p>Sotiburafusp alfa is a humanized bispecific fusion protein comprising a VEGFR-1 extracellular domain fragment (129-228, 1-100 in the current sequence) connected</p>Pureza:98%Forma y color:SolidPD-1/PD-L1-IN-52
<p>PD-1/PD-L1-IN-52 (Compound Ⅲ-5) is an orally active inhibitor of PD-1/PD-L1 interaction, exhibiting an IC50 of 109.9 nM. It demonstrates antitumor activity in a C57BL/6 mouse model of MC38 colon carcinoma cells expressing human PD-1, achieving a tumor growth inhibition (TGI) rate of 49.6%.</p>Forma y color:Odour Solid
