TNF
Los inhibidores del factor de necrosis tumoral (TNF) son compuestos que bloquean la actividad del TNF, una citocina involucrada en la inflamación y la regulación de la apoptosis. El TNF puede inducir apoptosis en algunos tipos celulares mientras promueve la supervivencia y la inflamación en otros. Inhibir el TNF es crucial en el tratamiento de enfermedades autoinmunes, condiciones inflamatorias crónicas y ciertos tipos de cáncer. Los inhibidores de TNF ayudan a modular la respuesta inmunitaria y a reducir el daño tisular causado por la inflamación excesiva. En CymitQuimica, ofrecemos una amplia gama de inhibidores de TNF de alta calidad para apoyar su investigación en inmunología, inflamación y apoptosis.
Se han encontrado 92 productos de "TNF"
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BIIB023
<p>BIIB023 is a human monoclonal antibody (mAb) that targets TNFRSF12A/TWEAKR/CD266. It is applicable for research in lupus nephritis and rheumatoid arthritis.</p>Forma y color:Odour LiquidHS-243
CAS:<p>HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.</p>Fórmula:C17H16N4O3Pureza:98.62%Forma y color:SolidPeso molecular:324.33EJMC-1
CAS:<p>EJMC-1 is an inhibitor of TNF-α with an IC50 value of 42 μM and can be used in studies about auto-inflammatory diseases.</p>Fórmula:C17H11ClN2O4SPureza:98.38%Forma y color:SolidPeso molecular:374.8Varlilumab
CAS:<p>Varlilumab (CDX-1127) is a novel human IgG1 anti-CD27 monoclonal antibody. Varlilumab has antitumor activity and can be used to study advanced solid tumors.</p>Pureza:SDS-PAGE:95% SEC-HPLC:98.65%Forma y color:LiquidPeso molecular:146 kDaLenercept
CAS:<p>Lenercept (Ro 45-2081) is a recombinant fusion protein combining the soluble TNF-receptor (p55) with the Fc portion of human IgG1 [1].</p>Forma y color:LiquidRO7567132
<p>RO7567132 is a bispecific antibody that binds and agonizes LTBR bivalently while binds and antagonizes FAP monovalently, inducing the formation of local TLS.</p>Forma y color:Odour LiquidAtibuclimab
CAS:<p>Atibuclimab is a chimeric monoclonal antibody targeting CD14, consisting of a mouse variable region and a human IgG4 Fc region.</p>Pureza:> 95% - > 95%Forma y color:LiquidPeso molecular:145.28 kDaGiloralimab
CAS:<p>Giloralimab (ABBV-927) is a antibody targeting CD40 with anticancer activity for the study of triple-negative breast cancer and non-small cell lung cancer.</p>Pureza:95.6% (SDS-PAGE); 95.1% (SEC-HPLC) - 95.6% (SDS-PAGE); 95.1% (SEC-HPLC)Forma y color:LiquidAnti-Mouse TNF α Antibody (TN3-19.12)
<p>Anti-Mouse TNF alpha Antibody is a rat-derived IgG inhibitor targeting mouse TNF alpha.</p>Pureza:95% - ＞10mg/mlForma y color:Odour LiquidTengonermin
CAS:<p>Tengonermin (ARENEGYR), a vascular agent, is TNF-α fused with CNGRCG peptide, enhancing chemo and T-cell access in tumors.</p>Forma y color:LiquidPegsunercept
CAS:<p>Pegsunercept (PEG sTNF-RI), a pegylated monoclonal antibody, selectively binds to TNFA, incorporating a polyethylene glycol (pegol) moiety [1].</p>Forma y color:LiquidPlaculumab
CAS:<p>Placulumab (ART621), an anti-TNF α monoclonal antibody, targets inflammation, potentially aiding arthritis treatment.</p>Forma y color:LiquidNerelimomab
CAS:<p>Nerelimomab (BAYX1351), an anti-TNF-α antibody, is utilized in sepsis research [1] [2].</p>Forma y color:LiquidCot inhibitor-1 hydrochloride
<p>Cot inhibitor-1 hydrochloride blocks TPL-2 kinase (IC50=28nM) and TNF-α synthesis (IC50=5.7nM) in human blood.</p>Fórmula:C27H28Cl3FN8Pureza:98.26%Forma y color:SoildPeso molecular:589.92Dapirolizumab
<p>Dapirolizumab is an anti-CD40 monoclonal antibody used in research on systemic lupus erythematosus (SLE) and other autoimmune diseases.</p>Pureza:>95%Forma y color:LiquidPeso molecular:145.5 kDaAsunercept
CAS:<p>Asunercept (APG101/CAN008) is a CD95-Fc protein targeting CD95L, used in GBM, MDS, and GvHD research.</p>Forma y color:LiquidZigakibart
CAS:<p>Zigakibart (BION-1301) is a humanized monoclonal antibody targeting TNFSF13 with anti-inflammatory activity for the study of immunoglobulin A nephropathy (IgAN)</p>Pureza:95.8% (SDS-PAGE); 99.8% (SEC-HPLC) - 95.8% (SDS-PAGE); 99.8% (SEC-HPLC)Forma y color:LiquidRanevetmab
CAS:<p>Ranevetmab (NV-01), a caninized anti-NGF mAb, relieves pain in DJD research.</p>Forma y color:LiquidRagifilimab
CAS:<p>Ragifilimab (INCAGN-1876), a GITR-targeting agonist antibody, may treat advanced solid tumors.</p>Pureza:SDS-PAGE:95% SEC-HPLC:99.99%Forma y color:LiquidPeso molecular:146.46 kDaTNF α Protein, Human, Recombinant (aa 77-233, His)
<p>TNF alpha Protein, Human, Recombinant (aa 77-233, His) is expressed in E.</p>Pureza:Greater than 95% as determined by reducing SDS-PAGE - SDS-PAGE: 99.66%; SEC-HPLC: 96.3%Forma y color:Lyophilized PowderPeso molecular:16 KDa (reducing condition)
