TNF
Los inhibidores del factor de necrosis tumoral (TNF) son compuestos que bloquean la actividad del TNF, una citocina involucrada en la inflamación y la regulación de la apoptosis. El TNF puede inducir apoptosis en algunos tipos celulares mientras promueve la supervivencia y la inflamación en otros. Inhibir el TNF es crucial en el tratamiento de enfermedades autoinmunes, condiciones inflamatorias crónicas y ciertos tipos de cáncer. Los inhibidores de TNF ayudan a modular la respuesta inmunitaria y a reducir el daño tisular causado por la inflamación excesiva. En CymitQuimica, ofrecemos una amplia gama de inhibidores de TNF de alta calidad para apoyar su investigación en inmunología, inflamación y apoptosis.
Se han encontrado 92 productos de "TNF"
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Mitazalimab
CAS:<p>Mitazalimab (ADC-1013/JNJ-64457107) is a CD40 agonist that stimulates T cells to attack tumors and remodels the tumor microenvironment.</p>Pureza:95.1% (SDS-PAGE); 98.7% (SEC-HPLC) - 95.1% (SDS-PAGE); 98.7% (SEC-HPLC)Forma y color:LiquidSPD304 dihydrochloride
CAS:<p>SPD304 dihydrochloride is a selective inhibitor of TNF-α with an IC50 of 22 µM. SPD304 dihydrochloride promotes dissociation of TNF trimers.</p>Fórmula:C32H34Cl2F3N3O2Pureza:99.25%Forma y color:SolidPeso molecular:620.53GSK2593074A
CAS:<p>GSK2593074A (GSK'074) is a programmed necrosis inhibitor that displays inhibitory effects on RIP1 and RIP3.</p>Fórmula:C27H23N5OSPureza:99.76%Forma y color:SolidPeso molecular:465.57BMS-561392
CAS:<p>BMS-561392 (DPC333) is a tumor necrosis factor-α ( TNF-α) Invertase inhibitor.</p>Fórmula:C27H32N4O4Pureza:99.16%Forma y color:SolidPeso molecular:476.57PK68
CAS:<p>PK68 selectively inhibits RIPK1 (IC50=90nM), potentially useful in inflammation and cancer metastasis studies.</p>Fórmula:C22H24N4O3SPureza:98.09% - 99.64%Forma y color:SolidPeso molecular:424.52Trovafloxacin mesylate
CAS:<p>Trovafloxacin: broad-spectrum fluoroquinolone, blocks DNA gyrase/topoisomerase IV and PANX1 channel (IC50=4μM).</p>Fórmula:C21H19F3N4O6SPureza:99.18%Forma y color:SolidPeso molecular:512.46C 87
CAS:<p>C 87: Small-molecule TNF-α inhibitor, binds TNFα, inhibits cytotoxicity with IC50 of 8.73 μM, blocks signaling.</p>Fórmula:C24H15ClN6O3SPureza:≥98%Forma y color:SolidPeso molecular:502.93Boserolimab
CAS:<p>Boserolimab (MK-5890) is a chimeric, humanized IgG1κ antibody that targets the signaling regulatory protein CD27 in mice.</p>Forma y color:LiquidCDC801
CAS:<p>CDC801 is an inhibitor of PDE4 and TNF-α with IC50s of 1.1 μM and 2.5 μM, respectively.</p>Fórmula:C23H24N2O5Pureza:99.61%Forma y color:SolidPeso molecular:408.45TNF-α-IN-2
CAS:<p>TNF-α-IN-2 is orally active TNFα inhibitor that distorts the TNFα trimer, causing abnormal signal transduction when it binds to TNFR1, rheumatoid arthritis.</p>Fórmula:C25H21ClF2N6OPureza:99.92%Forma y color:SolidPeso molecular:494.92TNF-α-IN-14
CAS:<p>TNF-α-IN-14, a potent TNFα inhibitor, exhibits a selective inhibition profile with an IC50 of 1.1 µM and demonstrates antiinflammatory properties (WO2001072735A2; compound 12) [1].</p>Fórmula:C22H26O6Forma y color:SolidPeso molecular:386.44TNF-α-IN-12
CAS:<p>TNF-α-IN-12, a TNF-α inhibitor with an IC50 of 0.1 μM, can reduce TNF-α blood levels [1].</p>Fórmula:C21H22O6Forma y color:SolidPeso molecular:370.4
