TNF
Los inhibidores del factor de necrosis tumoral (TNF) son compuestos que bloquean la actividad del TNF, una citocina involucrada en la inflamación y la regulación de la apoptosis. El TNF puede inducir apoptosis en algunos tipos celulares mientras promueve la supervivencia y la inflamación en otros. Inhibir el TNF es crucial en el tratamiento de enfermedades autoinmunes, condiciones inflamatorias crónicas y ciertos tipos de cáncer. Los inhibidores de TNF ayudan a modular la respuesta inmunitaria y a reducir el daño tisular causado por la inflamación excesiva. En CymitQuimica, ofrecemos una amplia gama de inhibidores de TNF de alta calidad para apoyar su investigación en inmunología, inflamación y apoptosis.
Se han encontrado 109 productos para "TNF".
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Onercept
CAS:Onercept, a recombinant soluble form of the human tumor necrosis factor-alpha (TNF-α) p55 receptor, is utilized in the study of Crohn's disease [1].Forma y color:LiquidIBI356
IBI356 is a humanized monoclonal antibody inhibitor that targets OX40L/CD134L/CD252. It can be utilized in the study of chronic inflammatory skin diseases, such as atopic dermatitis.Forma y color:Odour LiquidGB-223
GB-223 is a human monoclonal antibody (mAb) that targets TNFSF11/RANKL/CD254. It is applicable in the study of giant cell tumors of bone and postmenopausal osteoporosis.Forma y color:Odour LiquidPegsunercept
CAS:Pegsunercept (PEG sTNF-RI), a pegylated monoclonal antibody, selectively binds to TNFA, incorporating a polyethylene glycol (pegol) moiety [1].Forma y color:LiquidLenercept
CAS:Lenercept (Ro 45-2081) is a recombinant fusion protein combining the soluble TNF-receptor (p55) with the Fc portion of human IgG1 [1].Forma y color:LiquidEfaprinermin alfa
CAS:Efaprimermin alfa (OMP-336B11) is a human monoclonal antibody that targets TNFRSF18, and functions as a GITR ligand-Fc fusion protein [1].Forma y color:LiquidRanevetmab
CAS:Ranevetmab (NV-01), a caninized anti-NGF mAb, relieves pain in DJD research.Forma y color:LiquidGSK2800528
GSK2800528 is a human monoclonal antibody (mAb) targeting TNFSF2/TNFa, utilized for research related to inflammation and psoriasis.Forma y color:Odour LiquidAnti-Mouse TNF α Antibody (TN3-19.12)
Anti-Mouse TNF alpha Antibody is a rat-derived IgG inhibitor targeting mouse TNF alpha.Pureza:95%Forma y color:LiquidPeso molecular:150 kDaOnfekafusp alfa
CAS:Onfekafusp alfa (L19TNF), a trimeric fusion of L19 scFv and human TNF, targets malignant glioma.Forma y color:LiquidTNF α Protein, Ferret, Recombinant (His)
TNF alpha Protein, Ferret, Recombinant (His) is expressed in E.Forma y color:Lyophilized PowderPeso molecular:18.88 kDa (predicted) same as Tris-Bis PAGE result.TNF α Protein, Human, Recombinant (His & Avi), Biotinylated
TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.Forma y color:Lyophilized PowderPeso molecular:20.3 kDa (predicted). Due to glycosylation, the protein migrates to 21-24 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00121
5µg94,00€10µg138,00€20µg220,00€50µg434,00€100µg732,00€200µg1.324,00€500µg2.925,00€Anti-TNFR2/CD120b/TNFR1B Antibody (6I44)
Anti-TNFR2/CD120b/TNFR1B Antibody (6I44) is a Rabbit IgG monoclonal antibody targeting Mouse TNFR2/CD120b/TNFR1B.TNF α Protein, Human, Recombinant (aa 77-233, His)
TNF alpha Protein, Human, Recombinant (aa 77-233, His) is expressed in E.Pureza:Greater than 95% as determined by reducing SDS-PAGE - SDS-PAGE: 99.66%; SEC-HPLC: 96.3%Forma y color:Lyophilized PowderPeso molecular:16 KDa (reducing condition)TNF α Protein, Cynomolgus, Recombinant (His)
TNF alpha Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag.Forma y color:Lyophilized PowderPeso molecular:18.35 kDa (predicted). Due to glycosylation, the protein migrates to 19-25 kDa based on Tris-Bis PAGE result.TNF α Protein, Human, Recombinant (His & Avi)
TNF alpha Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.Pureza:> 90% as determined by Bis-Tris PAGE > 95% as determined by HPLC - > 90% as determined by Bis-Tris PAGE > 95% as determined by HPLCForma y color:White Lyophilized PowderPeso molecular:20.3 kDa (predicted). Due to glycosylation, the protein migrates to 21-25 kDa based on Tris-Bis PAGE result.TNF α Protein, Rabbit, Recombinant
Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily.Pureza:98% - > 99.9%Forma y color:White Lyophilized PowderPeso molecular:18 KDa (reducing condition)TNF α Protein, Human, Recombinant (aa 57-233, His)
TNF alpha Protein, Human, Recombinant (aa 57-233, His) is expressed in E.Forma y color:White Lyophilized PowderPeso molecular:18 KDa (reducing condition)Undecane (Standard)
CAS:Undecane (Standard) is the standard substance of Undecane, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Undecane is a high-purity biochemical reagent widely used in biochemical experiments and drug synthesis research.Fórmula:C11H24Forma y color:SolidPeso molecular:156.31Anti-TNF-α Antibody (5Z310)
Anti-TNF-alpha Antibody (5Z310) is a Mouse IgG1 monoclonal antibody targeting Human TNF-alpha.N-Formyl-Met-Leu-Phe
CAS:N-Formyl-Met-Leu-Phe (N-Formyl-MLF) (fMLF) is a synthetic peptide that acts as an agonist at formyl peptide receptors (FPR; Ki = 0.8 pM).Fórmula:C21H31N3O5SPureza:98.69% - 99.65%Forma y color:White SolidPeso molecular:437.55LASSBio-1135
CAS:LASSBio-1135 is an orally effective antagonist of TRPV1 and inhibitor of TNF-α production.Fórmula:C18H14N4Pureza:99.09%Forma y color:SolidPeso molecular:286.33R-7050
CAS:R-7050 (TNF-α Antagonist III), a tumor necrosis factor receptor (TNFR) antagonist, exhibits heightened selectivity for TNFα.Fórmula:C16H8ClF3N4SPureza:98.64% - 99.8%Forma y color:White SolidPeso molecular:380.77Ref: TM-T4637
1mg34,00€2mg43,00€5mg63,00€1mL*10mM (DMSO)71,00€10mg90,00€25mg195,00€50mg268,00€100mg439,00€200mg623,00€(Rac)-Benpyrine
CAS:(Rac)-Benpyrine is a potent and orally active inhibitor of TNF-α.Fórmula:C16H16N6OPureza:98.44%Forma y color:White SolidPeso molecular:308.34Ref: TM-T8692
1mg46,00€2mg62,00€5mg92,00€1mL*10mM (DMSO)105,00€10mg152,00€25mg295,00€50mg442,00€100mg620,00€200mg875,00€Hispidol
CAS:Hispidol ((Z)-Hispidol) ((Z)-Hispidol) is a potential therapeutic for inflammatory bowel disease; inhibits TNF-α induced adhesion of monocytes to colonFórmula:C15H10O4Pureza:97.86% - 98.45%Forma y color:SolidPeso molecular:254.24Ref: TM-T4319
1mg42,00€2mg56,00€1mL*10mM (DMSO)92,00€5mg93,00€10mg137,00€25mg200,00€50mg260,00€100mg409,00€200mg560,00€500mg954,00€STING-IN-2
CAS:STING-IN-2 (C-170) is a potent and covalent inhibitor of STING. STING-IN-2 can be used for autoinflammatory disease research.Fórmula:C15H16N2O4Pureza:98.61%Forma y color:SolidPeso molecular:288.3Roquinimex
CAS:Roquinimex (FCF89) (Linomide) is a quinoline derivative immunostimulant which increases NK cell activity and macrophage cytotoxicity; inhibits angiogenesis andFórmula:C18H16N2O3Pureza:97.69%Forma y color:SolidPeso molecular:308.33UTL-5g
CAS:UTL-5g is a chemoprotective TNF-α inhibitor reducing cisplatin side effects and toxicity in liver, kidneys, and blood.Fórmula:C11H8Cl2N2O2Pureza:99.83%Forma y color:White SolidPeso molecular:271.1Tulisokibart
CAS:Tulisokibart (PRA023) is a humanized anti-TNFSF15 monoclonal antibody used to study colon cancer.Pureza:98.38% (SEC-HPLC) - > 95%Forma y color:LiquidPeso molecular:143.96 kDaToralizumab
CAS:Toralizumab: humanized mAb targeting CD40L to curb T cell signaling and explore SLE treatment.Forma y color:LiquidPeso molecular:148.43 (kD)Afimkibart
CAS:Afimkibart (PF06480605) is a humanised monoclonal antibody targeting TL1A (TNF-like Ligand 1A), which blocks TL1A-DR3 (death domain receptor 3) signalling on restrictive immune cells and fibroblasts. It can be used for inflammatory bowel disease and ulcerative colitis.Pureza:95% - 99.2% (SDS-PAGE); 95.3% (SEC-HPLC)Forma y color:SoildPeso molecular:146.20 kDaTabalumab
CAS:Tabalumab (LY2127399) is a humanised monoclonal antibody targeting BAFF that neutralises both soluble and membrane-bound forms of BLyS , autoimmune diseases.Pureza:95%Forma y color:Transparent LiquidPeso molecular:146.24 kDaIratumumab
CAS:Iratumumab (MDX-060), a human IgG1κ anti-CD30 monoclonal antibody, halts CD30+ tumor growth, used in HL and ALCL research.Forma y color:LiquidDalnicastobart
CAS:Dalnicastobart (LVGN-7409) is a humanized monoclonal antibody targeting CD40/TNFRSF5 with agonist activity, immunostimulatory and antitumor.Pureza:95% - 97.4% (SDS-PAGE); 97.8% (SEC-HPLC)Forma y color:Transparent LiquidPeso molecular:146.33 kDaAfelimomab
CAS:Afelimomab (MAK 195F), a F(ab')2 fragment of an anti-tumor necrosis factor monoclonal antibody, is utilized in sepsis research [1].Forma y color:LiquidTecaginlimab
CAS:Tecaginlimab (BNT-312), an Fc-inert bispecific antibody, targets CD40/4-1BB to boost tumor immunity.Forma y color:LiquidAnti-Mouse CD40 Antibody (FGK4.5/FGK45)
Anti-Mouse CD40 Antibody (FGK4.5/FGK45) is a monoclonal antibody against mouse CD40 that specifically binds to the CD40 molecule and activates B cells and antigen-presenting cells. Anti-Mouse CD40 Antibody (FGK4.5/FGK45) enhances T cell responses, dendritic cell maturation, and NK cell activation. Anti-Mouse CD40 Antibody (FGK4.5/FGK45) can be used in research related to cancer, infection, inflammation, and immunology.Forma y color:Odour LiquidAnti-Mouse TNF-α/TNFSF2 Antibody (XT3.11)
The Anti-Mouse?TNF-alpha/TNFSF2 Antibody (XT3.11) is a rat-derived IgG1 monoclonal antibody targeting TNF-alpha/TNFSF2. The isotype control for this product is RatIgG1kappa, Isotype Control.Licaminlimab
Licaminlimab (OCS-02) is a single-chain antibody fragment targeting TNF alpha, an inflammatory cytokine.Forma y color:Odour LiquidAnti-Mouse TNFR2 Antibody (TR75-54.7)
Anti-Mouse TNFR2 Antibody (TR75-54.7) is a monoclonal antibody that reduces white blood cell counts and decreases pro-inflammatory cytokine expression.Forma y color:Transparent LiquidPeso molecular:~150 kDaBleselumab
CAS:Bleselumab (ASKP 1240) is a humanised monoclonal antibody targeting CD40, inhibiting immune responses, organ transplant rejection.Pureza:95%Forma y color:LiquidPeso molecular:144.16 kDaCifurtilimab
CAS:Cifurtilimab (SEA-CD40) is a humanised monoclonal antibody acting as a CD40 agonist. It enhances binding to activated FcγRIIIa, anticancer.Pureza:95%Forma y color:Transparent LiquidPeso molecular:145.10 kDaRavagalimab
CAS:Ravagalimab (ABBV-323) is a CD40 antagonist monoclonal antibody, investigated for Crohn’s disease and Sjögren’s syndrome to evaluate immune modulation.Pureza:95% - 96.9% (SDS-PAGE); 99.5% (SEC-HPLC)Forma y color:Transparent LiquidPeso molecular:145.95 kDaAnti-Mouse TL1A/TNFSF15 Antibody (5G4.6)
Anti-Mouse TL1A/TNFSF15 Antibody (5G4.6) is an IgG antibody inhibitor derived from the American hamster, specifically targeting the mouse TL1A/TNFSF15.Forma y color:Odour LiquidSelicrelumab
CAS:Selicrelumab (RG-7876) is an antibody targeting CD40 with potential anti-tumor activity for the study of pancreatic cancer.Pureza:98.7% (SDS-PAGE); 95.2% (SEC-HPLC) - 98.7% (SDS-PAGE); 95.2% (SEC-HPLC)Forma y color:LiquidPeso molecular:146.2 kDaTNF-α-IN-1
CAS:TNF-α-IN-1 is a TNF-α inhibitor.Fórmula:C16H14ClN3O5Pureza:98.82%Forma y color:Brown SolidPeso molecular:363.75Ref: TM-T13175
1mg56,00€5mg120,00€10mg178,00€1mL*10mM (DMSO)203,00€25mg330,00€50mg505,00€100mg713,00€Mitazalimab
CAS:Mitazalimab (ADC-1013/JNJ-64457107) is a CD40 agonist that stimulates T cells to attack tumors and remodels the tumor microenvironment.Pureza:95.1% (SDS-PAGE); 98.7% (SEC-HPLC) - 95.1% (SDS-PAGE); 98.7% (SEC-HPLC)Forma y color:LiquidPeso molecular:143.42 kDaUCB-5307
CAS:UCB-5307 inhibits TNFR1, binds TNFα with 9 nM KD, shows slow kinetics (KD=6 nM), and penetrates hTNF/hTNFR1 complexes.Fórmula:C22H21N3OPureza:98.76%Forma y color:White SolidPeso molecular:343.42SPD304 dihydrochloride
CAS:SPD304 dihydrochloride is a selective inhibitor of TNF-α with an IC50 of 22 µM. SPD304 dihydrochloride promotes dissociation of TNF trimers.Fórmula:C32H34Cl2F3N3O2Pureza:99.25%Forma y color:SolidPeso molecular:620.53Ref: TM-T12985
1mg63,00€5mg137,00€1mL*10mM (DMSO)178,00€10mg205,00€25mg430,00€50mg620,00€100mg883,00€Trovafloxacin mesylate
CAS:Trovafloxacin: broad-spectrum fluoroquinolone, blocks DNA gyrase/topoisomerase IV and PANX1 channel (IC50=4μM).Fórmula:C21H19F3N4O6SPureza:99.18%Forma y color:SolidPeso molecular:512.46
