TNF
Los inhibidores del factor de necrosis tumoral (TNF) son compuestos que bloquean la actividad del TNF, una citocina involucrada en la inflamación y la regulación de la apoptosis. El TNF puede inducir apoptosis en algunos tipos celulares mientras promueve la supervivencia y la inflamación en otros. Inhibir el TNF es crucial en el tratamiento de enfermedades autoinmunes, condiciones inflamatorias crónicas y ciertos tipos de cáncer. Los inhibidores de TNF ayudan a modular la respuesta inmunitaria y a reducir el daño tisular causado por la inflamación excesiva. En CymitQuimica, ofrecemos una amplia gama de inhibidores de TNF de alta calidad para apoyar su investigación en inmunología, inflamación y apoptosis.
Se han encontrado 94 productos de "TNF"
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Placulumab
CAS:Placulumab (ART621), an anti-TNF α monoclonal antibody, targets inflammation, potentially aiding arthritis treatment.Forma y color:LiquidSotigalimab
CAS:Sotigalimab (APX 005) is a monoclonal antibody targeting CD40 with anticancer activity for the study of metastatic pancreatic cancer.Pureza:98.50% - 98.50%Forma y color:LiquidPeso molecular:144.35 kDaTulinercept
CAS:Tulinercept (OPRX-106), a monoclonal antibody, may be utilized in a range of biochemical research applications [1].Forma y color:LiquidTQB2916
TQB2916 is a humanized IgG2 monoclonal antibody agonist that targets CD40. It exhibits significant antitumor activity by occupying CD40 and activating immune function. TQB2916 is applicable for research in advanced solid tumors and lymphomas.Forma y color:Odour LiquidXmAb-2513
XmAb-2513 is a humanized monoclonal antibody inhibitor targeting CD30. It demonstrates significant anti-proliferative activity along with excellent antibody-dependent cellular cytotoxicity (ADCC) and antibody-dependent cellular phagocytosis (ADCP). XmAb-2513 is applicable in research on hematological malignancies such as Hodgkin lymphoma (HL) and anaplastic large cell lymphoma (ALCL).Forma y color:Odour LiquidMK-1248
MK-1248 is a human IgG4 monoclonal antibody (mAb) targeting TNFSF18. It enhances the proliferative response of tumor-infiltrating lymphocytes to anti-CD3 stimulation and promotes the production of anti-tumor associated regulatory cytokines. MK-1248 is utilized in research on solid tumors.Forma y color:Odour LiquidGSK2800528
GSK2800528 is a human monoclonal antibody (mAb) targeting TNFSF2/TNFa, utilized for research related to inflammation and psoriasis.Forma y color:Odour LiquidGB-223
GB-223 is a human monoclonal antibody (mAb) that targets TNFSF11/RANKL/CD254. It is applicable in the study of giant cell tumors of bone and postmenopausal osteoporosis.Forma y color:Odour LiquidIBI356
IBI356 is a humanized monoclonal antibody inhibitor that targets OX40L/CD134L/CD252. It can be utilized in the study of chronic inflammatory skin diseases, such as atopic dermatitis.Forma y color:Odour LiquidBC011
BC011 is a human monoclonal antibody (mAb) targeting TNFRSF1B. It enhances the proliferation of CD8+ T cells and depletes Treg cells, resulting in an increased proportion of effector T cells within the tumor microenvironment. BC011 is applicable in the study of tumor immunology.Forma y color:Odour LiquidBCMA72-80
CAS:BCMA72-80: HLA-A2-specific peptide with high affinity; used in multiple myeloma and other BCMA+ tumor research.Fórmula:C59H97N13O11SPureza:98%Forma y color:SolidPeso molecular:1196.55Adalimumab β
CAS:Adalimumab beta (ABP-501) is an anti-TNF-α monoclonal antibody utilized in the study of rheumatoid arthritis (RA) [1].Forma y color:LiquidDapirolizumab
Dapirolizumab is an anti-CD40 monoclonal antibody used in research on systemic lupus erythematosus (SLE) and other autoimmune diseases.Pureza:>95%Forma y color:LiquidPeso molecular:150 kDaHS-243
CAS:HS-243 is an inhibitor of IRAK-4 and IRAK-1 with IC50s of 20 and 24 nM. HS-243 shows anti-inflammatory and anticancer activity.
Fórmula:C17H16N4O3Pureza:98.62%Forma y color:SolidPeso molecular:324.33TNF α Protein, Rabbit, Recombinant
Tumor necrosis factor alpha (TNFα) is the prototypic ligand of the TNF superfamily.Pureza:98% - > 99.9%Forma y color:Lyophilized PowderPeso molecular:18 KDa (reducing condition)TNF α Protein, Human, Recombinant (aa 57-233, His)
TNF alpha Protein, Human, Recombinant (aa 57-233, His) is expressed in E.Forma y color:Lyophilized PowderPeso molecular:18 KDa (reducing condition)Ref: TM-TMPJ-00125
5µg113,00€10µg178,00€20µg284,00€50µg523,00€100µg779,00€200µg1.142,00€500µg1.923,00€1mg2.758,00€TNF α Protein, Human, Recombinant (aa 77-233, His)
TNF alpha Protein, Human, Recombinant (aa 77-233, His) is expressed in E.Pureza:Greater than 95% as determined by reducing SDS-PAGE - SDS-PAGE: 99.66%; SEC-HPLC: 96.3%Forma y color:Lyophilized PowderPeso molecular:16 KDa (reducing condition)Ref: TM-TMPJ-00124
5µg42,00€10µg59,00€20µg87,00€50µg130,00€100µg210,00€200µg354,00€500µg709,00€1mg1.017,00€TNF α Protein, Human, Recombinant (His & Avi), Biotinylated
TNF alpha Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.Forma y color:Lyophilized PowderPeso molecular:20.3 kDa (predicted). Due to glycosylation, the protein migrates to 21-24 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00121
5µg91,00€10µg150,00€20µg239,00€50µg471,00€100µg779,00€200µg1.410,00€500µg3.018,00€TNF α Protein, Cynomolgus, Recombinant (His)
TNF alpha Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag.Forma y color:Lyophilized PowderPeso molecular:18.35 kDa (predicted). Due to glycosylation, the protein migrates to 19-25 kDa based on Tris-Bis PAGE result.TNF α Protein, Human, Recombinant (His & Avi)
TNF alpha Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.Pureza:> 90% as determined by Bis-Tris PAGE > 95% as determined by HPLC - > 90% as determined by Bis-Tris PAGE > 95% as determined by HPLCForma y color:Lyophilized PowderPeso molecular:20.3 kDa (predicted). Due to glycosylation, the protein migrates to 21-25 kDa based on Tris-Bis PAGE result.
