CymitQuimica logo
p53

p53

Los inhibidores de p53 se dirigen a la proteína p53, un supresor tumoral que desempeña un papel crucial en la regulación del ciclo celular, la reparación del ADN y la apoptosis. Aunque p53 a menudo está mutado o inactivado en células cancerosas, su inhibición a veces es necesaria para proteger a las células sanas de la apoptosis durante ciertos tratamientos. Por otro lado, restaurar la función de p53 en los tumores puede conducir a la apoptosis de las células cancerosas. La investigación sobre inhibidores de p53 es compleja y significativa tanto para comprender los mecanismos del cáncer como para desarrollar nuevas terapias. En CymitQuimica, ofrecemos una selección de inhibidores y moduladores de p53 de alta calidad para apoyar su investigación en biología del cáncer, apoptosis y desarrollo terapéutico.

Se han encontrado 63 productos para "p53".

Ordenar por

Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
productos por página.
  • Amifostine trihydrate

    CAS:
    Amifostine trihydrate (WR2721) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.
    Fórmula:C5H15N2O3PS·3H2O
    Pureza:99.71% - 99.80%
    Forma y color:Solid
    Peso molecular:268.27

    Ref: TM-T6381

    5mg
    34,00€
    10mg
    46,00€
    25mg
    73,00€
    50mg
    92,00€
    100mg
    130,00€
    500mg
    250,00€
  • Leptomycin B

    CAS:
    Leptomycin B: potent CRM1 inhibitor, blocks protein nuclear export and cell cycle, antifungal, modifies cysteine.
    Fórmula:C33H48O6
    Pureza:97.10% - 99.04%
    Forma y color:Solid
    Peso molecular:540.73

    Ref: TM-T15735

    1mg
    192,00€
    1mL*10mM (DMSO)
    268,00€
    2mg
    324,00€
    5mg
    587,00€
    10mg
    835,00€
    25mg
    1.251,00€
    50mg
    1.684,00€
    100mg
    2.277,00€
  • BIX-01294 trihydrochloride

    CAS:
    BIX-01294 trihydrochloride is an inhibitor of G9a histone methyltransferase.In a cell-free assay, the IC50=2.7 μM for G9a histone methyltransferase.
    Fórmula:C28H38N6O2·3HCl
    Pureza:99.41% - 99.95%
    Forma y color:Solid
    Peso molecular:600.02

    Ref: TM-T1959

    2mg
    50,00€
    5mg
    67,00€
    10mg
    102,00€
    1mL*10mM (DMSO)
    105,00€
    25mg
    182,00€
    50mg
    259,00€
    100mg
    447,00€
    200mg
    607,00€
  • Theaflavin 3,3′-digallate

    CAS:
    Theaflavin 3,3'-digallate, a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancer
    Fórmula:C43H32O20
    Pureza:98.71% - 99.86%
    Forma y color:Solid
    Peso molecular:868.70

    Ref: TM-T5429

    1mg
    87,00€
    5mg
    169,00€
    10mg
    268,00€
    1mL*10mM (DMSO)
    268,00€
    25mg
    462,00€
    50mg
    647,00€
    100mg
    873,00€
    200mg
    1.153,00€
  • Nutlin-3a

    CAS:
    Nutlin-3a is the active enantiomer of Nutlin-3, an MDM2 antagonist that inhibits MDM2-p53 interaction. Nutlin-3a has antitumor activity. Cost-effective and quality-assured.
    Fórmula:C30H30Cl2N4O4
    Pureza:95.62% - 99.71%
    Forma y color:Solid
    Peso molecular:581.49

    Ref: TM-T6023

    1mg
    50,00€
    2mg
    66,00€
    5mg
    90,00€
    1mL*10mM (DMSO)
    128,00€
    10mg
    156,00€
    25mg
    254,00€
    50mg
    376,00€
    100mg
    557,00€
  • YK-3-237

    CAS:
    YK-3-237 (B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid) reduces acetylation of mtp53 and exhibits anti-proliferative
    Fórmula:C19H21BO7
    Pureza:99.47%
    Forma y color:Solid
    Peso molecular:372.18

    Ref: TM-T9320

    5mg
    37,00€
    1mL*10mM (DMSO)
    42,00€
    10mg
    55,00€
    25mg
    105,00€
    50mg
    173,00€
    100mg
    304,00€
  • NSC 66811

    CAS:
    NSC 66811 inhibits MDM2-p53 interaction with 120 nM affinity, activating p53 in cancer cells.
    Fórmula:C23H20N2O
    Pureza:96.94%
    Forma y color:Orange Solid
    Peso molecular:340.42

    Ref: TM-T21578

    5mg
    43,00€
    1mL*10mM (DMSO)
    47,00€
    10mg
    58,00€
    25mg
    95,00€
    50mg
    128,00€
    100mg
    185,00€
    200mg
    269,00€
  • O6-Benzylguanine

    CAS:
    O6-Benzylguanine is a guanine analog with antineoplastic activity,and is a potent O6-alkylguanine DNA alkyltransferase (AGT) inactivator.
    Fórmula:C12H11N5O
    Pureza:98.90%
    Forma y color:Solid
    Peso molecular:241.25

    Ref: TM-T7539

    25mg
    47,00€
    50mg
    64,00€
    100mg
    90,00€
    500mg
    210,00€
  • UNC0224

    CAS:
    UNC0224 is a selective inhibitor of G9a with a Ki of 2.6 nM and IC50 of 15 nM. UNC0224 also potently inhibits GLP with assay-dependent IC50 values of 20-58 nM.
    Fórmula:C26H43N7O2
    Pureza:99.80%
    Forma y color:Yellow Solid
    Peso molecular:485.67

    Ref: TM-T17203

    1mg
    34,00€
    5mg
    66,00€
    1mL*10mM (DMSO)
    71,00€
    10mg
    99,00€
    25mg
    192,00€
    50mg
    334,00€
    100mg
    567,00€
  • NSC 146109 hydrochloride

    CAS:
    NSC 146109 hydrochloride is an activator of p53 targeting MDMX. NSC 146109 hydrochloride can be used for studies on breast cancer.
    Fórmula:C17H17ClN2S
    Pureza:99.28%
    Forma y color:Solid
    Peso molecular:316.85

    Ref: TM-T12257

    5mg
    38,00€
    1mL*10mM (DMSO)
    43,00€
    10mg
    56,00€
  • UNC0321

    CAS:
    UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays.
    Fórmula:C27H45N7O3
    Pureza:99.80%
    Forma y color:White Solid
    Peso molecular:515.69

    Ref: TM-T17204

    1mg
    44,00€
    5mg
    87,00€
    10mg
    137,00€
    25mg
    260,00€
    50mg
    409,00€
    100mg
    590,00€
  • BML-259

    CAS:
    BML-259 inhibits CDK5/CDK2 (IC50: 64/98 nM) for cancer and neurodegeneration research.
    Fórmula:C14H16N2OS
    Pureza:99.84%
    Forma y color:Solid
    Peso molecular:260.35

    Ref: TM-T36964

    5mg
    48,00€
    1mL*10mM (DMSO)
    50,00€
    10mg
    80,00€
    25mg
    160,00€
    50mg
    264,00€
    100mg
    462,00€
    500mg
    982,00€
  • PDK4-IN-1 hydrochloride

    CAS:
    PDK4-IN-1 hydrochloride is an anthraquinone derivative and a potent and orally active inhibitor of pyruvate dehydrogenase kinase 4 (PDK4, IC50 value = 84 nM).
    Fórmula:C22H20ClN3O2
    Pureza:99.67%
    Forma y color:Solid
    Peso molecular:393.87

    Ref: TM-T12412L

    1mg
    70,00€
    5mg
    150,00€
    1mL*10mM (DMSO)
    165,00€
    10mg
    215,00€
    25mg
    358,00€
    50mg
    515,00€
    100mg
    707,00€
    200mg
    1.009,00€