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IAP

IAP

Los inhibidores de las proteínas inhibidoras de la apoptosis (IAP) son compuestos que bloquean la actividad de las IAP, una familia de proteínas que previenen la apoptosis al inhibir caspasas y otros componentes de la maquinaria apoptótica. Los inhibidores de IAP promueven la apoptosis en células cancerosas al neutralizar estas señales de supervivencia, lo que los convierte en herramientas importantes en la investigación y terapia contra el cáncer. En CymitQuimica, ofrecemos una amplia gama de inhibidores de IAP de alta calidad para apoyar su investigación en oncología, apoptosis y desarrollo terapéutico.

Se han encontrado 66 productos de "IAP"

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  • Isolinderalactone
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    Isolinderalactone

    CAS:
    <p>Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.</p>
    Fórmula:C15H16O3
    Pureza:99.62%
    Forma y color:Solid
    Peso molecular:244.29

    Ref: TM-T8213

  • Polygalacin D
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    Polygalacin D

    CAS:
    <p>Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-induced</p>
    Fórmula:C57H92O27
    Pureza:98.95% - ≥98%
    Forma y color:Solid
    Peso molecular:1209.4

    Ref: TM-TN2091

  • 4-Methylsalicylic acid
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    4-Methylsalicylic acid

    CAS:
    <p>4-Methylsalicylic acid is used to inhibit the medium chain acyl-CoA synthetase.</p>
    Fórmula:C8H8O3
    Pureza:99.64%
    Forma y color:Solid Solid Crystalline
    Peso molecular:152.15

    Ref: TM-T22225

  • SM-164
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    SM-164

    CAS:
    <p>SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50: 1.39 nM). It acts as an extremely potent antagonist of XIAP.</p>
    Fórmula:C62H84N14O6
    Pureza:98.53% - 99.92%
    Forma y color:Solid
    Peso molecular:1121.42

    Ref: TM-T12932L

  • MX69
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    MX69

    CAS:
    <p>MX69 is the MDM2/XIAP inhibitor, blocking the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation.</p>
    Fórmula:C27H26N2O4S
    Pureza:97.27% - 99.57%
    Forma y color:Solid
    Peso molecular:474.57

    Ref: TM-T3653

  • BV6
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    BV6

    CAS:
    <p>BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family.</p>
    Fórmula:C70H96N10O8
    Pureza:97.46% - 99.82%
    Forma y color:Solid
    Peso molecular:1205.57

    Ref: TM-T6428

  • AZD5582 acetate (1258392-53-8 free base)
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    AZD5582 acetate (1258392-53-8 free base)

    <p>AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively.</p>
    Fórmula:C60H82N8O10
    Pureza:97.76%
    Forma y color:Solid
    Peso molecular:1075.36

    Ref: TM-T14378L

  • T-3256336
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    T-3256336

    CAS:
    <p>T-3256336 is an oral IAP blocker targeting cIAP-1, cIAP-2, and XIAP.</p>
    Fórmula:C31H45F2N5O5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:605.72

    Ref: TM-T26246

  • MX107
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    MX107

    CAS:
    <p>MX107 is a survivin inhibitor which induces degradation of XIAP and/or cIAP1, and suppresses genotoxic NF-kappaB activation.</p>
    Fórmula:C24H28N2O2
    Forma y color:Solid
    Peso molecular:376.49

    Ref: TM-T69845

  • A 410099.1
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    A 410099.1

    CAS:
    <p>A 410099.1 is a BIRC (baculoviral IAP repeat-containing protein) inhibitor with EC50 values of 4.6, 9.2, 15.6, 19.9, and 93.9 nM for BIRC2/3/4/7/8.</p>
    Fórmula:C27H41ClN4O3
    Pureza:99.30%
    Forma y color:Solid
    Peso molecular:505.1

    Ref: TM-T36890

  • MDM2/XIAP-IN-3
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    MDM2/XIAP-IN-3

    CAS:
    <p>MDM2/XIAP-IN-3 (compound 3e), a dual inhibitor of MDM2/XIAP, diminishes MDM2 and XIAP protein levels while augmenting p53 expression, consequently suppressing</p>
    Fórmula:C29H30N2O5S
    Forma y color:Solid
    Peso molecular:518.62

    Ref: TM-T79483

  • CUDC-427
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    CUDC-427

    CAS:
    <p>CUDC-427 (GDC-0917) is an orally bioactive and pan antagonist of inhibitor of apoptosis proteins(IAPs). CUDC-427 can be used in research on cancers.</p>
    Fórmula:C29H36N6O4S
    Pureza:99.92%
    Forma y color:Solid
    Peso molecular:564.7

    Ref: TM-T15018

  • Anticancer agent 128
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    Anticancer agent 128

    CAS:
    <p>Anticancer agent 128 (compound 1) is an IAP inhibitor that covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, exhibiting IC50 values of 24.9 nM, 19</p>
    Fórmula:C26H38N4O4
    Pureza:98%
    Forma y color:Solid
    Peso molecular:470.6

    Ref: TM-T79248

  • Anticancer agent 127
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    Anticancer agent 127

    CAS:
    <p>Anticancer agent 127 (142D6), an IAP inhibitor, covalently binds to the BIR3 domains of XIAP, cIAP1, and cIAP2, with IC50 values of 12 nM, 14 nM, and 9 nM,</p>
    Fórmula:C26H37FN4O6S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:552.66

    Ref: TM-T79247

  • Logo de CymitQuimica
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    XIAP degrader-1

    <p>XIAP degrader-1 is a small primary amine molecule that promotes the degradation of X-linked apoptosis inhibitory protein (XIAP).</p>
    Fórmula:C34H45N5O4
    Forma y color:Solid
    Peso molecular:587.75

    Ref: TM-T64161

  • Logo de CymitQuimica
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    XIAP/cIAP1 antagonist-1

    <p>Potent oral XIAP/cIAP1 inhibitor with EC50s: XIAP 5.1 nM, cIAP1 0.32 nM; curbs tumor growth in vivo.</p>
    Forma y color:Solid

    Ref: TM-T64302