IAP
Los inhibidores de las proteínas inhibidoras de la apoptosis (IAP) son compuestos que bloquean la actividad de las IAP, una familia de proteínas que previenen la apoptosis al inhibir caspasas y otros componentes de la maquinaria apoptótica. Los inhibidores de IAP promueven la apoptosis en células cancerosas al neutralizar estas señales de supervivencia, lo que los convierte en herramientas importantes en la investigación y terapia contra el cáncer. En CymitQuimica, ofrecemos una amplia gama de inhibidores de IAP de alta calidad para apoyar su investigación en oncología, apoptosis y desarrollo terapéutico.
Se han encontrado 71 productos para "IAP".
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CD47 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
CD47 (Cluster of Differentiation 47) also known as integrin associated protein (IAP) is a transmembrane protein that in humans is encoded by the CD47 gene.Forma y color:Lyophilized PowderPeso molecular:15 kDa (predicted). Due to glycosylation, the protein migrates to 45-65 kDa based on Tris-Bis PAGE result.CD47 Protein, Mouse, Recombinant (hFc)
CD47 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Forma y color:White Lyophilized PowderPeso molecular:40.6 kDa (predicted)CD47 Protein, Human, Recombinant
CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3.Pureza:97.8%Forma y color:Lyophilized PowderPeso molecular:14.5 kDa (predicted); 35 kDa (reducing condition, due to glycosylation)Alkaline phosphatase/ALPI Protein, Human, Recombinant (His)
Alkaline phosphatase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Pureza:98.4%Forma y color:White Lyophilized PowderPeso molecular:54 kDa (predicted); 66 kDa (reducing condition, due to glycosylation)Ref: TM-TMPY-02650
5µg78,00€10µg110,00€20µg177,00€50µg348,00€100µg595,00€200µg1.009,00€500µg2.043,00€ASTX660
CAS:Tolinapant (ASTX660) is an orally bioavailable cIAP1/2 and XIAP antagonist.Cost-effective and quality-assured.Fórmula:C30H42FN5O3Pureza:98.33% - 99.85%Forma y color:White SolidPeso molecular:539.68Ref: TM-TQ0029
1mg79,00€5mg137,00€1mL*10mM (DMSO)163,00€10mg205,00€25mg409,00€50mg605,00€100mg860,00€Polygalacin D
CAS:Polygalacin D shows anti- proliferation, anti-inflammary, and hepatoprotective activities, it can inhibit the expression of lipopolysaccharide (LPS)-inducedFórmula:C57H92O27Pureza:98.95% - ≥98%Forma y color:SolidPeso molecular:1209.4GDC-0152
CAS:GDC-0152 is a potent inhibitor of IAPs.Fórmula:C25H34N6O3SPureza:97.18% - 99.32%Forma y color:SolidPeso molecular:498.64Birinapant
CAS:Birinapant (TL32711) is a synthetic small molecule that is both a peptidomimetic of second mitochondrial-derived activator of caspases (SMAC) and inhibitor ofFórmula:C42H56F2N8O6Pureza:97.08% - ≥95%Forma y color:SolidPeso molecular:806.94Ref: TM-T6007
1mg34,00€2mg46,00€5mg70,00€1mL*10mM (DMSO)92,00€10mg109,00€25mg172,00€50mg250,00€100mg447,00€4-Methylsalicylic acid
CAS:4-Methylsalicylic acid is used to inhibit the medium chain acyl-CoA synthetase.Fórmula:C8H8O3Pureza:99.64%Forma y color:White SolidPeso molecular:152.15SM-164
CAS:SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains (IC50: 1.39 nM). It acts as an extremely potent antagonist of XIAP.Fórmula:C62H84N14O6Pureza:98.53% - 99.92%Forma y color:SolidPeso molecular:1121.42BV6
CAS:BV6 is an antagonist of c-IAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family.Fórmula:C70H96N10O8Pureza:97.46% - 99.82%Forma y color:SolidPeso molecular:1205.57Ref: TM-T6428
1mg47,00€2mg62,00€5mg94,00€10mg137,00€1mL*10mM (DMSO)170,00€25mg270,00€50mg442,00€100mg707,00€MX69
CAS:MX69 is the MDM2/XIAP inhibitor, blocking the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation.Fórmula:C27H26N2O4SPureza:97.27% - 99.57%Forma y color:SolidPeso molecular:474.57Ref: TM-T3653
2mg39,00€5mg58,00€1mL*10mM (DMSO)62,00€10mg92,00€25mg167,00€50mg260,00€100mg409,00€200mg590,00€Xevinapant
CAS:Xevinapant (Debio-1143) is a potent Smac mimetic and an antagonist of IAP, binding to XIAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3.Fórmula:C32H43N5O4Pureza:98% - 99.94%Forma y color:SolidPeso molecular:561.71Ref: TM-T6763
1mg40,00€2mg54,00€5mg88,00€10mg124,00€1mL*10mM (DMSO)138,00€25mg260,00€50mg416,00€100mg647,00€200mg954,00€AZD5582 acetate (1258392-53-8 free base)
AZD5582 acetate is an inhibitor of IAPs, which binds to the BIR3 domains cIAP1, cIAP2, and XIAP with IC50s of 15, 21, and 15 nM, respectively.Fórmula:C60H82N8O10Pureza:97.76%Forma y color:White SolidPeso molecular:1075.36LCL161
CAS:LCL161 is a SMAC mimetic, an IAP antagonist with oral activity that inhibits XIAP and cIAP1. LCL161 has potential antitumor activity. Cost-effective and quality-assured.Fórmula:C26H33FN4O3SPureza:99.13% - 99.87%Forma y color:White SolidPeso molecular:500.63Isolinderalactone
CAS:Isolinderalactone shows anti-inflammatory and anticancer capacity, and it exhibits moderate iNOS inhibitory activity, with the IC50 value of 0.30 uM.Fórmula:C15H16O3Pureza:98.76%Forma y color:SolidPeso molecular:244.29Embelin
CAS:Embelin (Embelic acid), isolated from the Japanese Ardisia herb, is an inhibitor of the X-linked inhibitor of apoptosis (IC50: 4.1 uM).Fórmula:C17H26O4Pureza:97.07% - 99.95%Forma y color:SolidPeso molecular:294.39CD47 Protein, Rhesus macaque, Recombinant (His & Flag)
CD47, also known as Integrin‑Associated Protein (IAP) and OA3, is a glycosylated atypical member of the immunoglobulin superfamily.Forma y color:Lyophilized PowderPeso molecular:33-55 KDa (reducing condition)Ref: TM-TMPJ-00614
5µg92,00€10µg149,00€20µg231,00€50µg439,00€100µg682,00€200µg1.063,00€500µg1.918,00€1mg2.890,00€CD47 Protein, Rhesus macaque, Recombinant (hFc)
CD47 Protein, Rhesus macaque, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag.Forma y color:Lyophilized PowderPeso molecular:60-90 KDa (reducing condition)Ref: TM-TMPJ-00613
5µg84,00€10µg120,00€20µg178,00€50µg351,00€100µg563,00€200µg888,00€500µg1.710,00€1mg2.457,00€CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated
CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag.Forma y color:Lyophilized PowderPeso molecular:60-70 KDa (reducing condition)
