Kinesina
Los inhibidores de cinesina se dirigen a las proteínas motoras cinesinas, responsables del transporte de carga celular a lo largo de los microtúbulos y que desempeñan un papel clave en la división celular, especialmente durante la mitosis. Las cinesinas están involucradas en el movimiento de cromosomas y otros orgánulos durante la división celular. Inhibir las cinesinas puede interrumpir estos procesos, lo que lleva al arresto del ciclo celular y a la posible muerte celular, lo que hace que estos inhibidores sean valiosos en la investigación del cáncer. En CymitQuimica, ofrecemos una gama diversa de inhibidores de cinesina de alta calidad para apoyar su investigación en biología celular, mitosis y terapia contra el cáncer.
Se han encontrado 67 productos de "Kinesina"
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S-trityl-L-Cysteine
CAS:<p>S-trityl-L-Cysteine is a potent inhibitor of human mitotic kinesin Eg5</p>Fórmula:C22H21NO2SPureza:97.02%Forma y color:Almost White To Light Yellow Granular PowderPeso molecular:363.47CW-069
CAS:<p>CW-069 (IC50=75 μM）, an allosteric selective inhibitor of microtubule motor protein HSET, exhibits remarkable specificity over KSP.</p>Fórmula:C23H21IN2O3Pureza:97.52% - 99.52%Forma y color:SolidPeso molecular:500.33SB-743921 hydrochloride
CAS:<p>SB-743921 hydrochloride (SB743921 HCl) is an effective inhibitor of kinesin spindle protein, KSP, (Ki =0.1 nM).</p>Fórmula:C31H34Cl2N2O3Pureza:95.58% - 99.70%Forma y color:SolidPeso molecular:553.52Mps1-IN-3 hydrochloride
<p>Mps1-IN-3 HCl: potent Mps1 inhibitor (IC50: 50 nM), hampers glioblastoma growth, enhances vincristine efficacy in vivo.</p>Fórmula:C26H32ClN7O4SForma y color:SolidPeso molecular:574.09Mps1-IN-1 dihydrochloride
CAS:Mps1-IN-1 dihydrochloride, a potent ATP-competitive inhibitor of Mps1 kinase, exhibits an IC50 of 367 nM.Fórmula:C28H35Cl2N5O4SForma y color:SolidPeso molecular:608.58Ispinesib
CAS:<p>Ispinesib (SB-715992), a selective, effectvie and reversible inhibitor of kinesin spindle protein (KSP), is derived from quinazolinone, with antineoplastic</p>Fórmula:C30H33ClN4O2Pureza:98% - 99.09%Forma y color:SolidPeso molecular:517.06GSK-923295
CAS:<p>GSK923295 is a selective allosteric inhibitor of CENP-E kinesin motor ATPase(Ki=3.2 nM).</p>Fórmula:C32H38ClN5O4Pureza:96.22% - 98.02%Forma y color:SolidPeso molecular:592.13BTB-1
CAS:<p>BTB-1 (NSC156750) is a novel small molecule inhibitor of the mitotic motor protein Kif18A.</p>Fórmula:C12H8ClNO4SPureza:99.71%Forma y color:SolidPeso molecular:297.71Sovilnesib
CAS:<p>Sovilnesib is a kinesin-like protein KIF18A inhibitor. Sovilnesib can be used for the cancer research.</p>Fórmula:C26H34F2N6O4SPureza:99.57%Forma y color:SolidPeso molecular:564.65K858 (Racemic)
CAS:<p>K858 Racemic (K858) is a selective mitotic kinesin Eg5 inhibitor which acts in an ATP-noncompetitive manner.</p>Fórmula:C13H15N3O2SPureza:>99.99%Forma y color:SolidPeso molecular:277.34Monastrol
CAS:<p>Monastrol ((±)-Monastrol) is a potent and cell-permeable inhibitor of the mitotic kinesin Eg5.</p>Fórmula:C14H16N2O3SPureza:98.02% - 98.59%Forma y color:SolidPeso molecular:292.35Dimethylenastron
CAS:<p>Dimethylenastron, an Eg5 inhibitor, arrests cells with monopolar spindles to which all chromosomes attach in a syntelic manner.</p>Fórmula:C16H18N2O2SPureza:98.07%Forma y color:SolidPeso molecular:302.39ARQ 621
CAS:<p>ARQ 621 is an allosteric, and selective Eg5 mitotic motor protein inhibitor. Phase 1.</p>Fórmula:C28H24Cl2FN5O2Pureza:97.01% - 98.38%Forma y color:SolidPeso molecular:552.43Mps1-IN-2
CAS:<p>Mps1-IN-2 is a potent, selective and ATP-competitive dual Mps1/Plk1 inhibitor.</p>Fórmula:C26H36N6O3Pureza:96.24% - 99.75%Forma y color:SolidPeso molecular:480.6BAY1217389
CAS:<p>BAY 1217389 is an effective and selective inhibitor of the monopolar spindle 1 (MPS1) kinase (IC50<10 nM).</p>Fórmula:C27H24F5N5O3Pureza:98.14% - 99.42%Forma y color:SolidPeso molecular:561.5Mps1-IN-1
CAS:<p>Mps1-IN-1 is a potent, selective and ATP-competitive inhibitor of Mps1 kinase (IC50 : 367 nM )</p>Fórmula:C28H33N5O4SPureza:98.33%Forma y color:SolidPeso molecular:535.66SR31527
CAS:<p>SR31527 chloride: potent KIFC1 inhibitor (IC50 6.6 µM), moderately impairs cell viability & colony growth.</p>Fórmula:C15H14ClN3OSPureza:98%Forma y color:SolidPeso molecular:319.81Eg5 Inhibitor V, trans-24
CAS:<p>Eg5 Inhibitor V, trans-24 is a specific and potent Eg5 inhibitor that can be used in cancer research with an IC50 value of 0.65 uM.</p>Fórmula:C26H21N3O3Pureza:99.75%Forma y color:SolidPeso molecular:423.46Kif15-IN-1
CAS:<p>Kif15-IN-1 is a Kif15 inhibitor with antiproliferative and potential anticancer activity, which can be used to study gastric cancer.</p>Fórmula:C20H22N4O5SPureza:99.39% - 99.39%Forma y color:SolidPeso molecular:430.48Litronesib Racemate
CAS:<p>Litronesib is a selective, allosteric inhibitor of kinesin Eg5.Litronesib (Racemate) is the racemate of litronesib.</p>Fórmula:C23H37N5O4S2Forma y color:SolidPeso molecular:511.7
