Kinesina
Los inhibidores de cinesina se dirigen a las proteínas motoras cinesinas, responsables del transporte de carga celular a lo largo de los microtúbulos y que desempeñan un papel clave en la división celular, especialmente durante la mitosis. Las cinesinas están involucradas en el movimiento de cromosomas y otros orgánulos durante la división celular. Inhibir las cinesinas puede interrumpir estos procesos, lo que lleva al arresto del ciclo celular y a la posible muerte celular, lo que hace que estos inhibidores sean valiosos en la investigación del cáncer. En CymitQuimica, ofrecemos una gama diversa de inhibidores de cinesina de alta calidad para apoyar su investigación en biología celular, mitosis y terapia contra el cáncer.
Se han encontrado 66 productos de "Kinesina"
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KSP-IA
CAS:<p>KSP-IA is a potent, specific, allosteric, and cell-active KSP inhibitor.</p>Fórmula:C21H22F2N2OPureza:98%Forma y color:SolidPeso molecular:356.41Luvixasertib hydrochloride
CAS:<p>CFI-402257 hydrochloride, a highly selective and orally bioavailable inhibitor targeting TTK/Mps1, demonstrates an in vitro IC50 value of 1.7 nM against TTK. This compound exhibits anti-cancer activity [1].</p>Fórmula:C28H31ClN6O3Forma y color:SolidPeso molecular:535.04MC-Val-Cit-PAB-Ispinesib
CAS:<p>MC-Val-Cit-PAB-Ispinesib (Compound 509) is a potent Eg5 inhibitor and a click chemistry reagent [1].</p>Fórmula:C59H71ClN10O10Forma y color:SolidPeso molecular:1115.71CCT251455
CAS:<p>CCT251455, the mitotic kinase monopolar spindle 1 (MPS1/TTK) inhibitor, is a potent (IC50=3 nM) and specific chemical tool.</p>Fórmula:C26H26ClN7O2Pureza:99.1% - 99.1%Forma y color:SolidPeso molecular:503.98Kif15-IN-2
CAS:<p>Kif15-IN-2 is a kinesin Kif15 inhibitor with potential anticancer activity and can be used in prostate cancer research.</p>Fórmula:C20H20N6O4SPureza:98.17%Forma y color:SolidPeso molecular:440.48NTRC 0066-0
CAS:<p>NTRC 0066-0 is a TTK inhibitor that can be used in cancer research.</p>Fórmula:C33H39N7O2Pureza:98.30%Forma y color:SolidPeso molecular:565.71Litronesib
CAS:<p>Litronesib is a selective inhibitor of mitosis-specific kinesin Eg5. It also has antitumor activity.</p>Fórmula:C23H37N5O4S2Pureza:98%Forma y color:SolidPeso molecular:511.7PVZB1194
CAS:<p>PVZB1194, a biphenyl-type inhibitor of Kinesin spindle protein Eg5 (KIF11), exhibits anticancer potential by inducing cell cycle arrest and apoptosis through</p>Fórmula:C13H9F4NO2SPureza:98%Forma y color:SolidPeso molecular:319.28SB-743921 free base
CAS:<p>SB-743921, a kinesin spindle protein (KSP) inhibitor, is used potentially for the treatment of non-Hodgkin's lymphoma (NHL).</p>Fórmula:C31H33ClN2O3Pureza:98%Forma y color:SolidPeso molecular:517.06CCT-271850
CAS:<p>CCT-271850 is an inhibitor of the spindle checkpoint function of Monospindle 1.</p>Fórmula:C24H29N7OPureza:98%Forma y color:SolidPeso molecular:431.53CFI-402257
CAS:<p>CFI-402257 is a selective inhibitor of Mps1/TTK kinase (Mps1 Ki = 0.09 nM; EC50 = 6.5 nM)and can be used in studies about hepatocellular carcinoma diseases.</p>Fórmula:C28H30N6O3Pureza:96.66% - 99.51%Forma y color:SolidPeso molecular:498.58Mps1-IN-8
CAS:<p>Mps1-IN-8, a Mps1 inhibitor, can be utilized in the study of various tumors [1].</p>Fórmula:C35H47N8O6PForma y color:SolidPeso molecular:706.77RMS-07
CAS:<p>RMS-07, a covalent MPS1/TTK inhibitor, has an IC50 of 13.1 nM, targeting a kinase hinge cysteine.</p>Fórmula:C35H40N8O2Forma y color:SolidPeso molecular:604.74MKLP2-IN-1
CAS:<p>MKLP2-IN-1 (compound 12a) is an inhibitor of MKLP2 that demonstrates excellent oral bioactivity. In vitro, MKLP2-IN-1 inhibits the ATPase activity stimulated by recombinant MKLP2 microtubules and, in a mouse Calu-6 lung cancer model, it effectively suppresses tumor growth.</p>Fórmula:C23H19BrFN3O2Forma y color:SolidPeso molecular:468.318Terpendole E
CAS:<p>Terpendole E is an atypical L5 site inhibitor.</p>Fórmula:C28H39NO3Forma y color:SolidPeso molecular:437.61Kolavenic acid analog
CAS:<p>KAA, an anticancer compound, inhibits centrosome clustering and targets HSET+ yeast and cancer cells.</p>Fórmula:C25H38O4Forma y color:SolidPeso molecular:402.57
