Integrin

ATN-161 trifluoroacetate salt is a novel integrin α5β1 antagonist that inhibits angiogenesis and growth of …

Cilengitide is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of …

Arg-Gly-Asp-Ser acetate is an integrin binding sequence that directly and specifically bind pro-caspase-8, pro-caspase-9 and …

Carvedilol Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking …

RWJ 50271 is a selective lymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1) interaction inhibitor( IC50 of 5.0 …

Tirofiban (MK-383) is a selective palate GPIIb/IIIa antagonist which inhibits platelet aggregation with IC50 of …

Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of …

GRGDSPK is an inhibitory peptide for RGD-mediated adhesion between integrin and extracellular matrix molecules.

Bimosiamose disodium has anti-inflammatory effects[1]. Bimosiamose disodium (TBC-1269Z) is a nonoligosaccharide pan-selectin inhibitor with IC50s …

LXW7 TFA, a cyclic peptide containing Arg-Gly-Asp (RGD), is an integrin αvβ3 inhibitor with an …

BIRT-377 is a negative allosteric and orally bioavailable inhibitor of ICAM-1 and LFA-1(Ki = 25.8 …

P8RI acetate is a biomimetic peptide of CD31 and an agonist of CDP8RI acetate shows …

Bimosiamose has anti-inflammatory effects[1]. Bimosiamose (TBC-1269) is a nonoligosaccharide pan-selectin antagonist with IC50s of 88 …

PLN-1474 is a potent αVβ1 inibitor with IC50 < 50nM (WO2021127483, compound 1)

Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.

Tirofiban hydrochloride monohydrate is a potent non-peptide, glycoprotein IIb/IIIa (integrins alphaIIbbetaIII) antagonist.

Bestatin (Ubenimex) hydrochlorideis an inhibitor of aminopeptidase N (APN)/CD13 and aminopeptidase B.

Hexapeptide-10 Acetate is a synthetic peptide. It increases the synthesis of laminin V and α6-integrin …

OSU-T315 (1,5-regioisomer) is a ILK inhibitor.

TR-14035 is a dual antagonist of α4β7/α4β1 integrins (IC50s: 7/87nM).

RGD peptide GRGDNP(2TFA) is a integrin-ligand interactions inhibitor.

Leukadherin-1 is an allosteric activator of CD11b/CD18. Increasing CD11b/CD18-dependent cell adhesion to fibrinogen, Decreasing leukocyte …

Cyclo(RGDyK) is a potent and selective αVβ3 integrin inhibitor with IC50 of 20 nM.

Cyclo (-RGDfK) is an effective and specific αvβ3 integrin inhibitor.

ILK-IN-3 is an inhibitor of integrin linked kinase, and with antitumor activity.

Cyclo(-RGDfK) is a selective αvβ3 integrin inhibitor(IC50 : 0.94 nM).

GLPG0187, a broad spectrum integrin receptor antagonist, inhibits αvβ1-integrin (IC50: 1.3 nM).

RGD Trifluoroacetate is a tripeptide that effectively triggers cell adhesion, addresses certain cell lines and …

A 286982 is an inhibitor that blocks the integrin-ligand interaction between leukocyte function-associated antigen-1 (LFA-1) …

Natalizumab used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease.

GRGDSP acetate is a synthetic linear RGD peptide and is an integrin inhibitor.

LXW7 is an octamer disulfide cyclic peptide and αvβ3 integrin ligand, acts as a potent …

Cyclo(RADfK) is a selective α(v)β(3) integrin ligand that has been extensively used for research, therapy, …

OSU-T315 is a novel potent, orally active ILK (integrin-linked kinase) inhibitor with IC50 of 0.6 …

P11 acetate is an integrin αvβ3-vitronectin interaction antagonist(IC50 = 2.74 nM).

α2β1 Integrin Ligand Peptide acetate is a potential antagonist of α2β1 integrin receptor. α2β1 Integrin …

E7820 is an angiogenesis inhibitor by suppressing integrin a2 (a cell adhesion molecule expressed on …

Cucurbitacin B has profound in vitro and in vivo antiproliferative effects against human pancreatic Y …

iRGD peptide is a 9-amino acid cyclic peptide (sequence: CRGDKGPDC) and a molecular mimicry agent …

Pyrintegrin is an β1-integrin agonist that promotes embryonic stem cells' survival. Pyrintegrin can be used …

Gly-Arg-Gly-Asp-Ser (GRGDS) acetate is a cell binding protein domain derived from the cell-binding region of …

A-205804 is a specific and effective inhibitor of E-selectin( IC50=20 nM ) and ICAM-1(IC50=25 nM) …

Cilengitide is a potent integrin inhibitor for the αvβ3/5 receptor (IC50: 4.1/79 nM, in cell-free …

PND-1186 (VS-4718) is a reversible and specific FAK inhibitor (IC50: 1.5 nM).

ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) …

RGD (Arg-Gly-Asp) Peptides is a cell adhesion motif which can mimic cell adhesion proteins and …

Carotegrast methyl, an orally-active small molecule, can antagonize the α4 integrin receptor. It is a …

Vaccarin is a major flavonoid glycoside in Vaccariae semen, its biotransformation pathways involves methylation, hydroxylation, …

Irigenin has antifungal activity.

CWHM-12 is a potent inhibitor of αV integrins (IC50s of 0.2/0.8/1.5/1.8 nM for αvβ8/αvβ3/αvβ6/αvβ1).

3'-Demethylnobiletin has chemopreventive effects on colon carcinogenesis, it can significantly inhibit the growth of human …

BIO-1211 is a more potent inhibitor of α4β1 (VLA-4, IC50 = 4 nM) over α4β7(IC50 …

Lifitegrast is a lymphocyte, function-associated antigen-1 antagonist.

SB273005 is a potent integrin inhibitor with Ki of 1.2 nM and 0.3 nM for …

Firategrast is an orally bioavailable antagonist of α4β1/α4β7 integrin.

αvβ1 integrin-IN-1 TFA is an effective and selective αvβ1 integrin inhibitor (IC50: 0.63 nM).

Balamapimod is a reversible inhibitor of Ras/Raf/MEK. It also has a potential anti-tumor activity.

Valategrast hydrochloride, a dual antagonist of integrin α4β1 (VLA-4), is used for the potential treatment …

BI-1950 is a highly potent lymphocyte function associated antigen-1 (LFA-1) inhibitor and the LFA-1 is …

β-glycosidase-IN-1 is a piperidine derivative, and is an inhibitor of β-glycosidase. It has hypoglycemic activity.