Integrin
Los inhibidores de integrinas se dirigen a las integrinas, una familia de receptores en la superficie celular que desempeñan un papel crucial en la adhesión celular, la migración y la transducción de señales. Las integrinas están involucradas en la regulación del ciclo celular, particularmente en procesos como la división y la diferenciación celular. Inhibir las integrinas puede interrumpir estos procesos, lo que lleva al arresto del ciclo celular y la apoptosis, lo que hace que estos inhibidores sean valiosos en la investigación del cáncer y el estudio de la metástasis. En CymitQuimica, ofrecemos una amplia gama de inhibidores de integrinas de alta calidad para apoyar su investigación en la regulación del ciclo celular, la biología del cáncer y el desarrollo terapéutico.
Se han encontrado 224 productos de "Integrin"
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Integrin Antagonists 27
CAS:<p>Integrin Antagonists 27 is a small molecule integrin αvβ3 antagonist. It has a binding affinity of 18 nM and as a novel anticancer agent.</p>Fórmula:C24H20N4O5Forma y color:SolidPeso molecular:444.44Lamifiban
CAS:<p>Lamifiban is a nonpeptide glycoprotein IIb/IIIa antagonist. It prevents platelet loss during experimental cardiopulmonary bypass.</p>Fórmula:C24H28N4O6Pureza:98%Forma y color:SolidPeso molecular:468.5SC-52012
CAS:<p>SC-52012 is a novel and potent fibrinogen receptor antagonist, an RGD mimetic, which inhibits platelet aggregation.</p>Fórmula:C25H30N4O6Pureza:97.20%Forma y color:SolidPeso molecular:482.53Gly-Arg-Gly-Asp-Ser TFA
CAS:<p>Gly-Arg-Gly-Asp-Ser (TFA), osteopontin domain, binds αvβ3 and αvβ5 integrins; IC50s: ~5 μM, ~6.5 μM.</p>Fórmula:C19H31F3N8O11Forma y color:SolidPeso molecular:604.49L 738167
CAS:<p>L 738167 is a potent antagonist of the long-acting fibrinogen receptor.</p>Fórmula:C25H34N6O6SForma y color:SolidPeso molecular:546.64L-739758
CAS:<p>L-739758 is a glycoprotein IIb/IIIa inhibitor.</p>Fórmula:C22H26N4O5S3Forma y color:SolidPeso molecular:522.66TC-I 15
CAS:<p>α2β1 integrin inhibitor</p>Fórmula:C23H28N4O6S2Pureza:98%Forma y color:SolidPeso molecular:520.62α7β1 integrin modulator-1
CAS:<p>α7β1 Integrin Modulator-1 is a potent modulator with research potential for muscular dystrophy [1].</p>Fórmula:C23H29N3O6SPureza:98%Forma y color:SolidPeso molecular:475.56BIO-7662
CAS:<p>BIO-7662 is an effective and highly selective antagonist of α4β1 integrin.</p>Fórmula:C38H48N6O8SPureza:98%Forma y color:SolidPeso molecular:748.89αvβ1 integrin-IN-2
CAS:<p>αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of ανβ1 and α5β1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively.</p>Fórmula:C29H38N4O4Pureza:98%Forma y color:SolidPeso molecular:506.64Lotrafiban hydrochloride
CAS:<p>Lotrafiban hydrochloride is an platelet glycoprotein IIb/IIIa blocker with oral activity.</p>Fórmula:C23H33ClN4O4Forma y color:SolidPeso molecular:464.99ATN-161
CAS:<p>ATN-161 is an integrin α5β1 binding peptide and antagonist that inhibits VEGF-induced hCECs migration and angiogenesis.</p>Fórmula:C23H35N9O8SPureza:98%Forma y color:SolidPeso molecular:597.64Roxifiban acetate
CAS:<p>Roxifiban acetate（DMP 754 acetate） is a potent GP IIb / IIIa antagonist that exhibits antiplatelet aggregation activity via immune mediation and can be used in</p>Fórmula:C23H33N5O8Pureza:97.91% - 98.36%Forma y color:SolidPeso molecular:507.54αvβ1 integrin-IN-1
CAS:<p>αvβ1 integrin-IN-1 is a potent and selective inhibitor of αvβ1 integrin (IC50 of 0.63 nM) with antifibrotic effects.</p>Fórmula:C26H34N6O6SPureza:99.74% - >99.99%Forma y color:SolidPeso molecular:558.65α5β1 integrin agonist-1
CAS:<p>α5β1 integrin agonist-1 is an α5β1 integrin agonist that selectively delivers 5-FU to tumour cells and induces tumour cell death.</p>Fórmula:C24H26FN5O9Forma y color:SolidPeso molecular:547.49SF0166
CAS:<p>SF0166: potent αvβ3 antagonist, IC50: 0.6 nM. Blocks cell adhesion, IC50: 7.6 pM-76 nM. Reduces neovascularization in mice.</p>Fórmula:C23H27F2N5O4Forma y color:SolidPeso molecular:475.49SR121566A
CAS:<p>SR121566A is a novel non-peptide antagonist of Glycoprotein IIb/IIIa (GP IIb-IIIa).</p>Fórmula:C20H25N5O4SPureza:98%Forma y color:SolidPeso molecular:431.51Zalunfiban dihydrochloride
<p>Zalunfiban (RUC-4) is a potent αIIbβ3 platelet antagonist, IC50 45 nM, used in myocardial infarction research.</p>Fórmula:C16H20Cl2N8O2SForma y color:SolidPeso molecular:459.356-B345TTQ
CAS:<p>6-B345TTQ is an α4 integrin inhibitor that can impede the interaction between α4 and Leupaxin. This compound is applicable for studies focused on inflammation research.</p>Fórmula:C22H20BrNO4Forma y color:SolidPeso molecular:442.303Des-ethyl-carafiban
CAS:<p>Des-ethyl-carafiban (Compound 44) is an antagonist of the fibrinogen receptor, effectively inhibiting platelet aggregation induced by various agonists. It is useful for research in thrombotic diseases.</p>Fórmula:C22H23N5O5Forma y color:SolidPeso molecular:437.448L 734217
CAS:<p>L 734217 is an antagonist of the fibrinogen receptor.</p>Fórmula:C18H31N3O4Pureza:98%Forma y color:SolidPeso molecular:353.46GSK3335103
CAS:<p>GSK3335103 is a non-peptide, orally active inhibitor of αvβ6 integrin (pIC50=8), employed in the study of pulmonary fibrosis.</p>Fórmula:C27H36FN3O4Forma y color:SolidPeso molecular:485.59Fradafiban
CAS:<p>Fradafiban binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM. Fradafiban is a non-polypeptide platelet glycoprotein IIb/IIIa antagonist.</p>Fórmula:C20H21N3O4Pureza:98%Forma y color:SolidPeso molecular:367.40GR 83895
CAS:<p>GR 83895 is an antagonist of prototype fibrinogen receptor.</p>Fórmula:C29H39N9O8SPureza:98%Forma y color:SolidPeso molecular:673.74
