Integrin
Los inhibidores de integrinas se dirigen a las integrinas, una familia de receptores en la superficie celular que desempeñan un papel crucial en la adhesión celular, la migración y la transducción de señales. Las integrinas están involucradas en la regulación del ciclo celular, particularmente en procesos como la división y la diferenciación celular. Inhibir las integrinas puede interrumpir estos procesos, lo que lleva al arresto del ciclo celular y la apoptosis, lo que hace que estos inhibidores sean valiosos en la investigación del cáncer y el estudio de la metástasis. En CymitQuimica, ofrecemos una amplia gama de inhibidores de integrinas de alta calidad para apoyar su investigación en la regulación del ciclo celular, la biología del cáncer y el desarrollo terapéutico.
Se han encontrado 279 productos de "Integrin"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
ICAM-1-IN-1
CAS:ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) inhibitor.Fórmula:C15H11BrN2O2SPureza:99.67%Forma y color:SolidPeso molecular:363.23Ref: TM-T13147
1mg175,00€5mg371,00€1mL*10mM (DMSO)409,00€10mg557,00€25mg887,00€50mg1.198,00€100mg1.611,00€500mg3.232,00€TAK 029
CAS:TAK 029 is a local glycoprotein IIb/IIIa receptor inhibitor.Fórmula:C19H23N5O7Forma y color:SolidPeso molecular:433.42BIO-7662
CAS:BIO-7662 is an effective and highly selective antagonist of α4β1 integrin.Fórmula:C38H48N6O8SPureza:98%Forma y color:SolidPeso molecular:748.89αvβ6 integrin inhibitor 2
CAS:αvβ6 Integrin Inhibitor 2 is a potent inhibitor of αvβ6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM.Fórmula:C21H30N4O3Pureza:98%Forma y color:SolidPeso molecular:386.49Synstatin (92-119)
CAS:Synstatin (92-119) serves as an anti-tumor agent by suppressing angiogenesis and cancer cell invasion, chiefly through the down-regulation of integrin αvβ3 andFórmula:C133H207N35O46Pureza:98%Forma y color:SolidPeso molecular:3032.27ATN-161
CAS:ATN-161 is an integrin α5β1 binding peptide and antagonist that inhibits VEGF-induced hCECs migration and angiogenesis.Fórmula:C23H35N9O8SPureza:98%Forma y color:SolidPeso molecular:597.64TC-I 15
CAS:α2β1 integrin inhibitorFórmula:C23H28N4O6S2Pureza:98%Forma y color:SolidPeso molecular:520.62L-739758
CAS:L-739758 is a glycoprotein IIb/IIIa inhibitor.Fórmula:C22H26N4O5S3Forma y color:SolidPeso molecular:522.66αvβ1 integrin-IN-2
CAS:αvβ1 integrin-IN-2 (compound 32) is a potent inhibitor of ανβ1 and α5β1 integrins, exhibiting IC50 values of 0.9 nM and 33 nM, respectively.Fórmula:C29H38N4O4Pureza:98%Forma y color:SolidPeso molecular:506.64Teclistamab
CAS:Teclistamab(JNJ-64007957) is a human bispecific monoclonal antibody targeting the CD3 receptor on t-cells and the BCMA for relapsed and refractory multiple myeloma.Pureza:95%Forma y color:LiquidPeso molecular:143.64 kDaLotrafiban hydrochloride
CAS:Lotrafiban hydrochloride is an platelet glycoprotein IIb/IIIa blocker with oral activity.Fórmula:C23H33ClN4O4Forma y color:SolidPeso molecular:464.99SC-52012
CAS:SC-52012 is a novel and potent fibrinogen receptor antagonist, an RGD mimetic, which inhibits platelet aggregation.Fórmula:C25H30N4O6Pureza:97.20%Forma y color:SolidPeso molecular:482.53Lotrafiban
CAS:Lotrafiban: Oral GP IIb/IIIa inhibitor for treating coronary and cerebrovascular disease.Fórmula:C23H32N4O4Forma y color:SolidPeso molecular:428.52Zaurategrast
CAS:Zaurategrast (CDP323) is an oral α4-integrin antagonist that blocks VCAM-1 interactions and is used to study immune cell trafficking.Fórmula:C26H25BrN4O3Pureza:98%Forma y color:SolidPeso molecular:521.41Lamifiban
CAS:Lamifiban is a nonpeptide glycoprotein IIb/IIIa antagonist. It prevents platelet loss during experimental cardiopulmonary bypass.Fórmula:C24H28N4O6Pureza:98%Forma y color:SolidPeso molecular:468.5SB-267268
CAS:SB-267268: αvβ3 inhibitor (IC50: 0.68 nM human, 0.29 nM mouse), blocks αvβ3/αvβ5 integrins (Ki: 0.9 nM human, 0.5 nM monkey αvβ3, 0.7 nM human αvβ5).Fórmula:C22H24F3N3O4Pureza:98%Forma y color:SolidPeso molecular:451.44αvβ1 integrin-IN-1
CAS:αvβ1 integrin-IN-1 is a potent and selective inhibitor of αvβ1 integrin (IC50 of 0.63 nM) with antifibrotic effects.Fórmula:C26H34N6O6SPureza:99.39% - 99.69%Forma y color:SolidPeso molecular:558.65Ref: TM-T13473
1mg109,00€5mg260,00€1mL*10mM (DMSO)319,00€10mg409,00€25mg660,00€50mg888,00€100mg1.224,00€200mg1.648,00€Roxifiban acetate
CAS:Roxifiban acetate（DMP 754 acetate） is a potent GP IIb / IIIa antagonist that exhibits antiplatelet aggregation activity via immune mediation and can be used inFórmula:C23H33N5O8Pureza:97.91% - 98.36%Forma y color:SolidPeso molecular:507.54Des-ethyl-carafiban
CAS:Des-ethyl-carafiban (Compound 44) is an antagonist of the fibrinogen receptor, effectively inhibiting platelet aggregation induced by various agonists. It is useful for research in thrombotic diseases.Fórmula:C22H23N5O5Forma y color:SolidPeso molecular:437.448GSK3335103
CAS:GSK3335103 is a non-peptide, orally active inhibitor of αvβ6 integrin (pIC50=8), employed in the study of pulmonary fibrosis.Fórmula:C27H36FN3O4Forma y color:SolidPeso molecular:485.59GR 83895
CAS:GR 83895 is an antagonist of prototype fibrinogen receptor.Fórmula:C29H39N9O8SPureza:98%Forma y color:SolidPeso molecular:673.74SF0166
CAS:SF0166: potent αvβ3 antagonist, IC50: 0.6 nM. Blocks cell adhesion, IC50: 7.6 pM-76 nM. Reduces neovascularization in mice.Fórmula:C23H27F2N5O4Forma y color:SolidPeso molecular:475.49Zalunfiban dihydrochloride
Zalunfiban (RUC-4) is a potent αIIbβ3 platelet antagonist, IC50 45 nM, used in myocardial infarction research.Fórmula:C16H20Cl2N8O2SForma y color:SolidPeso molecular:459.35Fradafiban
CAS:Fradafiban binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM. Fradafiban is a non-polypeptide platelet glycoprotein IIb/IIIa antagonist.Fórmula:C20H21N3O4Pureza:98%Forma y color:SolidPeso molecular:367.40L 734217
CAS:L 734217 is an antagonist of the fibrinogen receptor.Fórmula:C18H31N3O4Pureza:98%Forma y color:SolidPeso molecular:353.46OPN expression inhibitor 1
CAS:OPN expression inhibitor 1 is an osteopontin expression inhibitor used in the study of breast cancer metastasis.Fórmula:C25H33N3O5Pureza:99.78%Forma y color:SolidPeso molecular:455.55Ref: TM-T62820
1mg126,00€5mg258,00€1mL*10mM (DMSO)259,00€10mg385,00€25mg695,00€50mg1.009,00€100mg1.314,00€α5β1 integrin agonist-1
CAS:α5β1 integrin agonist-1 is an α5β1 integrin agonist that selectively delivers 5-FU to tumour cells and induces tumour cell death.Fórmula:C24H26FN5O9Forma y color:SolidPeso molecular:547.496-B345TTQ
CAS:6-B345TTQ is an α4 integrin inhibitor that can impede the interaction between α4 and Leupaxin. This compound is applicable for studies focused on inflammation research.Fórmula:C22H20BrNO4Forma y color:SolidPeso molecular:442.303SR121566A
CAS:SR121566A is a novel non-peptide antagonist of Glycoprotein IIb/IIIa (GP IIb-IIIa).Fórmula:C20H25N5O4SPureza:98%Forma y color:SolidPeso molecular:431.51
