Integrin
Los inhibidores de integrinas se dirigen a las integrinas, una familia de receptores en la superficie celular que desempeñan un papel crucial en la adhesión celular, la migración y la transducción de señales. Las integrinas están involucradas en la regulación del ciclo celular, particularmente en procesos como la división y la diferenciación celular. Inhibir las integrinas puede interrumpir estos procesos, lo que lleva al arresto del ciclo celular y la apoptosis, lo que hace que estos inhibidores sean valiosos en la investigación del cáncer y el estudio de la metástasis. En CymitQuimica, ofrecemos una amplia gama de inhibidores de integrinas de alta calidad para apoyar su investigación en la regulación del ciclo celular, la biología del cáncer y el desarrollo terapéutico.
Se han encontrado 224 productos de "Integrin"
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CLT-28643
CAS:<p>CLT-28643 is a specific α5β1-Integrin inhibitor that prevents fibrosis in GFS, inhibits tumor growth and angiogenesis, suppresses fibrosis and inflammation.</p>Fórmula:C19H17N3O4Pureza:99.89%Forma y color:SolidPeso molecular:351.36Integrin-IN-2
CAS:<p>Integrin-IN-2, an oral αv integrin blocker, enhances αvβ6/3/5/8 affinities with pIC50s: 7.8/8.4/8.4/7.4.</p>Fórmula:C27H30N4O3Pureza:98%Forma y color:SolidPeso molecular:458.55XVA143
CAS:<p>XVA143, an α/β I-like allosteric antagonist, blocks LFA-1 adhesion and combats P. gingivalis in mice, preventing bone loss.</p>Fórmula:C25H21Cl2N3O8Forma y color:SolidPeso molecular:562.36Integrin modulator 1
CAS:<p>Integrin modulator 1 is a selective α4β1 integrin agonist (IC50 9.8 nM) that enhances adhesion with EC50 12.9 nM, aiding integrin-dependent studies.</p>Fórmula:C13H14N2O4Pureza:99.61%Forma y color:SolidPeso molecular:262.26Firategrast
CAS:<p>Firategrast (SB 683699) is an orally active and specific α4β1/α4β7 integrin antagonist.Firategrast reduces the transport of lymphocytes into the central nervous</p>Fórmula:C27H27F2NO6Pureza:99.16%Forma y color:SolidPeso molecular:499.5Elarofiban
CAS:<p>Elarofiban(RWJ-53308) is a novel and orally active GPIIb/IIIa antagonist.</p>Fórmula:C22H32N4O4Pureza:98.76%Forma y color:SolidPeso molecular:416.513-Hydroxyxanthone
CAS:<p>3-Hydroxyxanthone (3-Hydroxy-xanthen-9-one), a xanthone derivative, exhibits inhibitory effects on NADPH-catalyzed lipid peroxidation in human umbilical vein</p>Fórmula:C13H8O3Pureza:98%Forma y color:SolidPeso molecular:212.2ICAM-1-IN-1
CAS:<p>ICAM-1-IN-1 is a potent and selective E-selectin(IC50 = 7 nM) and ICAM-1(IC50 = 5 nM) inhibitor.</p>Fórmula:C15H11BrN2O2SPureza:99.67%Forma y color:SolidPeso molecular:363.23BI-1950
CAS:<p>BI-1950: potent inhibitor of LFA-1, key in immune function and drug target.</p>Fórmula:C32H26Cl2FN7O3Pureza:98%Forma y color:SolidPeso molecular:646.5Teclistamab
CAS:<p>Teclistamab(JNJ-64007957) is a human bispecific monoclonal antibody targeting the CD3 receptor on t-cells and the BCMA for relapsed and refractory multiple myeloma.</p>Pureza:95%Forma y color:LiquidSynstatin (92-119)
CAS:<p>Synstatin (92-119) serves as an anti-tumor agent by suppressing angiogenesis and cancer cell invasion, chiefly through the down-regulation of integrin αvβ3 and</p>Fórmula:C133H207N35O46Pureza:98%Forma y color:SolidPeso molecular:3032.27TAK 029
CAS:<p>TAK 029 is a local glycoprotein IIb/IIIa receptor inhibitor.</p>Fórmula:C19H23N5O7Forma y color:SolidPeso molecular:433.42αvβ6 integrin inhibitor 2
CAS:<p>αvβ6 Integrin Inhibitor 2 is a potent inhibitor of αvβ6 integrin, demonstrating an inhibition concentration (IC50) of 96.5 nM.</p>Fórmula:C21H30N4O3Pureza:98%Forma y color:SolidPeso molecular:386.49Lotrafiban
CAS:<p>Lotrafiban: Oral GP IIb/IIIa inhibitor for treating coronary and cerebrovascular disease.</p>Fórmula:C23H32N4O4Forma y color:SolidPeso molecular:428.52JNJ-26076713
CAS:<p>JNJ-26076713, an oral alpha V integrin blocker, may treat macular edema, AMD, and diabetic retinopathy.</p>Fórmula:C29H38N4O3Pureza:98%Forma y color:SolidPeso molecular:490.64SB-267268
CAS:<p>SB-267268: αvβ3 inhibitor (IC50: 0.68 nM human, 0.29 nM mouse), blocks αvβ3/αvβ5 integrins (Ki: 0.9 nM human, 0.5 nM monkey αvβ3, 0.7 nM human αvβ5).</p>Fórmula:C22H24F3N3O4Pureza:98%Forma y color:SolidPeso molecular:451.44Zaurategrast
CAS:<p>Zaurategrast is an effective and oral-effective inhibitor of the α4-integrin.</p>Fórmula:C26H25BrN4O3Pureza:98%Forma y color:SolidPeso molecular:521.41Solitomab
CAS:<p>Solitomab (AMG 110) is a bispecific antibody targeting CD3 and EpCAM, used in uterine/ovarian carcinosarcoma research.</p>Forma y color:LiquidCarotegrast
CAS:<p>Carotegrast, an orally available α4 integrin receptor inhibitor, has anti-inflammatories activities.</p>Fórmula:C27H24Cl2N4O5Forma y color:SolidPeso molecular:555.41Tirofiban HCl
CAS:<p>Tirofiban HCl is an antagonist of platelet glycoprotein-IIb/IIIa receptor.</p>Fórmula:C22H37ClN2O5SPureza:98%Forma y color:SolidPeso molecular:477.06
