Ferroptosis
La ferroptosis es una forma de muerte celular regulada caracterizada por la acumulación de peróxidos lipídicos y el estrés oxidativo dependiente de hierro. A diferencia de la apoptosis, la ferroptosis no está impulsada por caspasas, sino por el fallo de las defensas antioxidantes celulares, lo que conduce a la muerte celular. Los inhibidores e inductores de la ferroptosis son fundamentales para estudiar esta vía única de muerte celular, que está implicada en diversas enfermedades, como el cáncer, la neurodegeneración y el daño por isquemia-reperfusión. En CymitQuimica, ofrecemos una amplia gama de moduladores de la ferroptosis de alta calidad para apoyar su investigación en mecanismos de muerte celular, estrés oxidativo y patología de enfermedades.
Se han encontrado 229 productos para "Ferroptosis".
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Ciclopirox
CAS:Ciclopirox is an antifungal that chelates Fe3+ and Al3+, inhibiting enzymes and has antibacterial and anti-inflammatory effects.Fórmula:C12H17NO2Pureza:99.78% - 99.78%Forma y color:Yellow SolidPeso molecular:207.27Butylhydroxyanisole
CAS:BHA is an antioxidant with two isomers: 2-tert-butyl-4-hydroxyanisole and 3-tert-butyl-4-hydroxyanisole.Fórmula:C11H16O2Pureza:99.54% - 99.63%Forma y color:SolidPeso molecular:180.25Pioglitazone
CAS:Pioglitazone (U 72107) is a selective and oral PPARγ agonist with EC50 of 0.93 and 0.99 μM on human and mouse PPARγ, respectively . High-Quality, Low-Cost!Fórmula:C19H20N2O3SPureza:95% - 99.82%Forma y color:White PowderPeso molecular:356.44Artesunate
CAS:Artesunate (WR-256283) is part of the artemisinin group of drugs that treat malaria.Fórmula:C19H28O8Pureza:97.67% - 99.9%Forma y color:White SolidPeso molecular:384.42Sulfasalazine
CAS:Sulfasalazine (Azulfidine) is a synthetic salicylic acid derivative. Sulfasalazine induces ferroptosis and inhibits NF-κB. Cost effective and quality assured.Fórmula:C18H14N4O5SPureza:98.00% - 99.28%Forma y color:Yellow SolidPeso molecular:398.39Deferiprone
CAS:Deferiprone (Deferidone) is an Iron Chelator. The mechanism of action of deferiprone is as an Iron Chelating Activity.Fórmula:C7H9NO2Pureza:99.58% - ≥95%Forma y color:White SolidPeso molecular:139.15Dopamine hydrochloride
CAS:Dopamine hydrochloride (ASL279) is a natural catecholamine neurotransmitter, dopamine receptors (D1-5 receptors) (EC50=2.7 nM). High-Quality, Low-Cost!Fórmula:C8H12ClNO2Pureza:99.47% - 99.95%Forma y color:White SolidPeso molecular:189.64NVS-ZP7-4
CAS:NVS-ZP7-4 is a inhibitor of Zinc transporter SLC39A7 (ZIP7).Fórmula:C28H28FN5OSPureza:99.86%Forma y color:SolidPeso molecular:501.62Ref: TM-T12277
1mg67,00€5mg147,00€1mL*10mM (DMSO)164,00€10mg250,00€25mg505,00€50mg767,00€100mg1.054,00€L-Glutathione reduced
CAS:L-Glutathione reduced (Glutathione) is a naturally occurring tripeptide found in cells as an endogenous antioxidant that scavenges oxygen free radicals.Fórmula:C10H17N3O6SPureza:97.37% - 99.99%Forma y color:White SolidPeso molecular:307.32Baicalein
CAS:Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor.Fórmula:C15H10O5Pureza:97.29% - 99.40%Forma y color:Yellow SolidPeso molecular:270.24Ethylenediaminetetraacetic acid trisodium salt
CAS:Ethylenediaminetetraacetic acid trisodium salt (EDTA Trisodium) used to bind metal ions in the chelation therapy.Fórmula:C10H13N2Na3O8Pureza:99.92% - 99.96%Forma y color:White SolidPeso molecular:358.19Sorafenib
CAS:Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57Fórmula:C21H16ClF3N4O3Pureza:98% - 99.89%Forma y color:White SolidPeso molecular:464.82Imidazole ketone erastin
CAS:View and buy Imidazole ketone erastin from TargetMol.Imidazole ketone erastin (IKE) is an inducer of ferroptosis. It has inhibition of the system Xc- cystine/glutamate transporter.Cited in 22 publications.Fórmula:C35H35ClN6O5Pureza:98.48% - 99.89%Forma y color:Yellow SolidPeso molecular:655.14Ref: TM-T5523
1mg66,00€2mg92,00€5mg144,00€1mL*10mM (DMSO)161,00€10mg185,00€25mg318,00€50mg485,00€100mg640,00€DL-Glutamine
CAS:DL-Glutamine, a non-essential amino acid, is abundant in the body, aids metabolism, carries nitrogen, and fuels cells.Fórmula:C5H10N2O3Pureza:99.89% - 99.98%Forma y color:White Crystalline Powder White Crystalline PowderPeso molecular:146.14Butylated hydroxytoluene
CAS:Butylated hydroxytoluene (BHT FCC/NF) is an organic chemical composed of 4-methylphenol modified with tert-butyl groups at positions 2 and 6.Fórmula:C15H24OPureza:99.72%Forma y color:SolidPeso molecular:220.35Curcumin
CAS:Curcumin (Natural Yellow 3) is a phenolic natural product, an inhibitor of histone acetyltransferase p300/CREB (IC50=25 μM) with specificity.Fórmula:C21H20O6Pureza:95% - 99.91%Forma y color:SolidPeso molecular:368.38iFSP1
CAS:iFSP1, a potent, selective, and glutathione-independent ferroptosis suppressor protein 1 (FSP1) (AIFM2) inhibitor with an EC50 of 103 nM, sensitizes diverseFórmula:C20H13N5Pureza:98.74% - 99.74%Forma y color:SolidPeso molecular:323.35FSEN1
CAS:FSEN1 is a novel and highly effective non-competitive FSP1 inhibitor with an IC50 value of 313 nM.Fórmula:C22H22BrN5OSPureza:99.54% - 99.97%Forma y color:White SolidPeso molecular:484.41Rosiglitazone maleate
CAS:Rosiglitazone maleate (BRL 49653) is an oral antidiabetic and potential anticancer agent.Fórmula:C22H23N3O7SPureza:99.33% - 99.51%Forma y color:SolidPeso molecular:473.50Ferumoxytol
CAS:Ferumoxytol is an iron oxide nanoparticle with anti-leukemia properties, specifically against acute myeloid leukemia (AML) cells with low ferroportin (FPN) expression. By increasing intracellular iron levels, Ferumoxytol induces the Fenton reaction to produce reactive oxygen species (ROS), resulting in oxidative stress and ferroptosis. It selectively kills leukemia cells with low FPN expression while sparing normal cells, making it useful for studying leukemia targeting iron metabolism abnormalities.Forma y color:Solid
