Ferroptosis
La ferroptosis es una forma de muerte celular regulada caracterizada por la acumulación de peróxidos lipídicos y el estrés oxidativo dependiente de hierro. A diferencia de la apoptosis, la ferroptosis no está impulsada por caspasas, sino por el fallo de las defensas antioxidantes celulares, lo que conduce a la muerte celular. Los inhibidores e inductores de la ferroptosis son fundamentales para estudiar esta vía única de muerte celular, que está implicada en diversas enfermedades, como el cáncer, la neurodegeneración y el daño por isquemia-reperfusión. En CymitQuimica, ofrecemos una amplia gama de moduladores de la ferroptosis de alta calidad para apoyar su investigación en mecanismos de muerte celular, estrés oxidativo y patología de enfermedades.
Se han encontrado 225 productos de "Ferroptosis"
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SP-420
CAS:SP-420 is a novel orally active iron chelator.Fórmula:C16H21NO6SPureza:99.39%Forma y color:SolidPeso molecular:355.41ML-210
CAS:ML-210 (CID 49766530) is a glutathione peroxidase 4 (GPX4) inhibitor. ML-210 has antitumor activity and induces ferroptosis. Cost-effective and quality-assured.Fórmula:C22H20Cl2N4O4Pureza:97% - 99.03%Forma y color:SolidPeso molecular:475.32Troglitazone
CAS:Troglitazone (Romglizone) is a PPARγ agonist with anti-inflammatory and anti-tumor activity.Fórmula:C24H27NO5SPureza:98% - 99.8%Forma y color:Yellow SolidPeso molecular:441.54L-BUTHIONINE-(S,R)-SULFOXIMINE
CAS:L-Buthionine-(S,R)-sulfoximine is a cell-permeable and irreversible inhibitor of γ-glutamylcysteine synthetase that induces oxidative stress by depleting GSH.Fórmula:C8H18N2O3SPureza:97.07% - ≥98%Forma y color:White Fine PowderPeso molecular:222.31DL-Buthionine-(S,R)-sulfoximine
CAS:DL-Buthionine-(S,R)-sulfoximine (Butionine sulfoximine) is an inhibitor of γ-glutamylcysteine synthetase for the treatment of solid tumors.Fórmula:C8H18N2O3SPureza:98% - 99.64%Forma y color:White Fine PowderPeso molecular:222.31SRS16-86
CAS:SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis.Fórmula:C26H32N4O2Pureza:97.73%Forma y color:SolidPeso molecular:432.56Pseudolaric Acid B
CAS:Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.Fórmula:C23H28O8Pureza:98.91% - 99.84%Forma y color:SolidPeso molecular:432.46Bay 11-7085
CAS:Bay 11-7085 can irreversibly inhibit the IκBα phosphorylation induced by TNFα (IC50: 10 μM).Fórmula:C13H15NO2SPureza:99.76% - 99.94%Forma y color:White SolidPeso molecular:249.33Levobupivacaine
CAS:<p>Levobupivacaine is an amino-amide local anaesthetic drug belonging to the family of n-alkylsubstituted pipecoloxylidide.</p>Fórmula:C18H28N2OPureza:99.72%Forma y color:SolidPeso molecular:288.43Liproxstatin-1
CAS:Liproxstatin-1 is a potent and selective inhibitor of iron death (IC50=22 nM).Fórmula:C19H21ClN4Pureza:97.11% - 99.44%Forma y color:SolidPeso molecular:340.85Rosiglitazone hydrochloride
CAS:Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.Fórmula:C18H19N3O3S·HClPureza:99.63% - 99.79%Forma y color:SolidPeso molecular:393.89SP600125
CAS:SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitiveFórmula:C14H8N2OPureza:97.63% - 99.82%Forma y color:SolidPeso molecular:220.23NADPH tetracyclohexanamine
CAS:<p>NADPH tetracyclohexanamine (NADPH (tetracyclohexanamine)) is a cofactor and biological reducing agent.</p>Fórmula:C45H82N11O17P3Pureza:98.73% - 99.05%Forma y color:SolidPeso molecular:1142.12L-Cystine
CAS:<p>L-Cystine (Cystine Acid) is not considered one of the 20 amino acids, L-Cystine (Cystine Acid) is a sulfur-containing derivative obtained from oxidation of</p>Fórmula:C6H12N2O4S2Pureza:99.59% - 99.85%Forma y color:White Solid PowderPeso molecular:240.30Rosiglitazone
CAS:Rosiglitazone (BRL49653) is a PPARγ agonist, TRPC5 activator, and TRPM3 inhibitor with oral activity.Fórmula:C18H19N3O3SPureza:98.61% - 99.87%Forma y color:White To Off-White Crystalline PowderPeso molecular:357.43JKE-1674
CAS:JKE-1674 is an orally active glutathione peroxidase 4 (GPX4) inhibitor and the active metabolite of ML-210.Cost-effective and quality-assured.Fórmula:C20H20Cl2N4O4Pureza:98.02% - 98.4%Forma y color:SolidPeso molecular:451.3L-Glutamic acid
CAS:<p>L-Glutamic acid is an agonist of glutamate receptors, including metabotropic glutamate receptors (mGluR), AMPA, NMDA, and KA. High-Quality, Low-Cost!</p>Fórmula:C5H9NO4Pureza:99.14% - 99.55%Forma y color:White Solid CrystallinePeso molecular:147.13ML385
CAS:ML385 is an NRF2 inhibitor (IC50=1.9 μM) with novelty and specificity.Fórmula:C29H25N3O4SPureza:98.08% - >99.99%Forma y color:SolidPeso molecular:511.59Necrostatin-1
CAS:Necrostatin-1 (Nec-1) is a necrotic apoptosis inhibitor and RIP1 inhibitor with specificity.Fórmula:C13H13N3OSPureza:99.25% - >99.99%Forma y color:SolidPeso molecular:259.33Siramesine hydrochloride
CAS:Siramesine hydrochloride (Lu 28-179 hydrochloride) is a selective sigma-2 receptor agonist, which has been shown to trigger cell death of Y cells and to exhibitFórmula:C30H32ClFN2OPureza:99.72% - >99.99%Forma y color:SolidPeso molecular:491.04
