Asociado a microtúbulos
Los inhibidores de proteínas asociadas a microtúbulos se dirigen a proteínas que interactúan con los microtúbulos, los componentes estructurales del citoesqueleto de la célula, esenciales para la división celular. Estas proteínas regulan la estabilidad y la dinámica de los microtúbulos durante la mitosis. Inhibir las proteínas asociadas a microtúbulos puede interrumpir la función de los microtúbulos, lo que lleva al arresto del ciclo celular y la apoptosis, particularmente en células cancerosas de rápida división. Estos inhibidores se utilizan ampliamente en la investigación del cáncer y el desarrollo de fármacos. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteínas asociadas a microtúbulos de alta calidad para apoyar su investigación en división celular, dinámica del citoesqueleto y terapia contra el cáncer.
Se han encontrado 285 productos de "Asociado a microtúbulos"
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Entasobulin
CAS:Entasobulin is an inhibitor of β-tubulin polymerization. It has a potential anticancer activity.Fórmula:C26H18ClN3O2Pureza:98.40%Forma y color:SolidPeso molecular:439.89Bepranemab
CAS:Bepranemab (UCB 0107) - humanized IgG4 monoclonal antibody targeting tau (235-250) for Alzheimer's research.Pureza:99% (SDS-PAGE); 96.8% (SEC-HPLC) - 99% (SDS-PAGE); 96.8% (SEC-HPLC)Forma y color:LiquidTubulin inhibitor 6
CAS:Tubulin inhibitor 6 (iHAP1) is an inhibitor of tubulin and a potent inhibitor of multiple cancer cell lines.Fórmula:C20H14ClNO2SPureza:99.05%Forma y color:SolidPeso molecular:367.85Verubulin hydrochloride
CAS:Verubulin hydrochloride (MPC-6827 hydrochloride) is an agent of blood brain barrier permeable microtubule-disrupting, with potent and broad-spectrum cytotoxicFórmula:C17H18ClN3OPureza:98.29% - 99.77%Forma y color:SolidPeso molecular:315.8Tilavonemab
CAS:Tilavonemab (ABBV-8E12), a humanized anti-tau antibody, halts tau uptake in neurons and may help with Alzheimer's research.Pureza:95.2% (SDS-PAGE); 96.6% (SEC-HPLC) - 95.2% (SDS-PAGE); 96.6% (SEC-HPLC)Forma y color:LiquidZagotenemab
CAS:<p>Zagotenemab: humanized antibody targeting tau protein to study neurological disorders, including Alzheimer's.</p>Pureza:95% - > 95%Forma y color:LiquidPeso molecular:145.3 kDaAC 7739
CAS:<p>AC 7739 is a microtubule protein binding agent with anticancer and antitumor activity that inhibits advanced solid tumors and in situ transplanted tumors.</p>Fórmula:C18H22ClNO4Pureza:99.38% - 99.55%Forma y color:SoildPeso molecular:351.83Tirbanibulin Mesylate
CAS:Tirbanibulin Mesylate (KX01 Mesylate) is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).Fórmula:C27H33N3O6SPureza:99%Forma y color:SolidPeso molecular:527.63DM4
CAS:DM4 (Ravtansine) can be used in the preparation of antibody drug conjugate and it is an antitubulin agent. It can inhibit cell division.Fórmula:C38H54ClN3O10SPureza:98.15%Forma y color:SolidPeso molecular:780.37BNC105
CAS:BNC105 is a tubulin polymerization inhibitor. It has potent antiproliferative and tumor vascular disrupting properties.Fórmula:C20H20O7Pureza:96.57%Forma y color:SolidPeso molecular:372.37TBL-100
TBL-100 is a human monoclonal antibody (mAb) that targets Tau. It is applicable for research in Alzheimer's disease (AD) and progressive supranuclear palsy.Forma y color:Odour LiquidT-900607
CAS:<p>T-900607 is a novel microtubule protein active agent that disrupts microtubule polymerization through a unique mechanism of action. t-900607 is cardiotoxic.</p>Fórmula:C14H10F5N3O4SPureza:98.84%Forma y color:SolidPeso molecular:411.3Sudocetaxel
CAS:<p>Sudocetaxel is a compound that serves as a microtubule depolymerization inhibitor, specifically designed for the pH-sensitive delivery of docetaxel.</p>Fórmula:C48H59NO16Forma y color:SolidPeso molecular:905.98Tubulin polymerization-IN-55
CAS:Tubulin polymerisation-IN-55 is a Tubulin Polymerization inhibitor that displays antiproliferative effects on A549, K562, HepG2, MDA-MB-231 and HFL-1.Fórmula:C22H24N2O4Pureza:98.68%Forma y color:SoildPeso molecular:380.44Tubulin inhibitor 48
CAS:Tubulin inhibitor 48 (compound 16) is an anticancer agent targeting microtubules. It exhibits IC50 values of 0.1 μM and 0.07 μM against LN-229 and Capan-1 cells, respectively.Fórmula:C21H22N4OForma y color:SolidPeso molecular:346.43Tubulin Polymerization-IN-1 prodrug
CAS:Tubulin Polymerization-IN-1 prodrug (Compound 2b) is a microtubule polymerization inhibitor prodrug mediated by Pd. Developed from colchicine-binding site inhibitors (CBSIs), it aims to reduce toxicity and enhance targeted release. Compared to the parent compound, its cytotoxicity is decreased by 68.3 times, but can be in situ restored in the presence of Pd resin. Mechanistic studies show it retains the same antitumor activity as CBSIs. In vivo tests demonstrate that, once activated by Pd resin, it significantly suppresses tumor growth (63.2% inhibition rate). Tubulin Polymerization-IN-1 prodrug is a promising candidate for cancer research.Fórmula:C22H23FN2O4Forma y color:SolidPeso molecular:398.43Cys-McMMAF
CAS:Cys-McMMAF, a microtubule-disrupting agent linked to an anti-5T4 antibody, shows antitumor effects in mouse models.Fórmula:C52H83N7O13SForma y color:SolidPeso molecular:1046.32Vinblastine
CAS:Vinblastine inhibits microtubule formation and suppresses nAChR activity with IC50 of 8.9 μM, used to treat certain kinds of cancer.Fórmula:C46H58N4O9Pureza:97.42%Forma y color:PowderPeso molecular:810.97Diminutol
CAS:Diminutol, a purine derivative, inhibits NQO1 (Ki=1.72μM), affects tubulin polymerization, and disrupts mitosis at 50μM without impacting Cdk1 or actin.Fórmula:C19H26N6OSForma y color:SolidPeso molecular:386.51Breast cancer targeting peptide 18-4
CAS:Breastcancertargeting peptide 18–4 is a keratin 1 (KRT1) receptor-targeting peptide with a dissociation constant (Kd) of 0.98 μM. Its amino acid sequence is WxEAAYQrFL, and it is an analogue of the P160 peptide. When covalently bonded with the anticancer peptide MccJ25, it significantly enhances MccJ25 uptake in breast cancer cells and boosts its anticancer efficacy. The IC50 values for this covalent compound are 14.2, 20, and 25 μM against MCF-7, MDA-MB-435, and MDA-MB-435-MDR, respectively.Fórmula:C63H89N15O15Peso molecular:1296.47cis-trismethoxy Resveratrol
CAS:<p>cis-trismethoxy Resveratrol ((Z)-3,5,4'-Trimethoxystilbene) inhibits tubulin polymerization (IC50 = 4 μM) and has anti-mitotic effects.</p>Fórmula:C17H18O3Pureza:99.88%Forma y color:SolidPeso molecular:270.32P160 peptide
CAS:P160 peptide is a breast cancer-targeting peptide that binds to the keratin 1 (KRT1) receptor in breast cancer cells, with a Kd of approximately 1.1 μM. It shows significant potential for targeted drug delivery to breast cancer cells. P160 peptide enhances the cellular uptake and anticancer activity of the pro-apoptotic antimicrobial peptide MccJ25 (microcin J25). It is applicable in cancer research studies.Fórmula:C74H105N17O17SPeso molecular:1536.79Tubulin polymerization-IN-69
Tubulin polymerization-IN-69 (compound 6c) exhibits significant inhibition of microtubule assembly in vitro, with an inhibition rate of 78.3% and an IC50 value of 6.53 μM. It rapidly induces apoptosis and G2/M phase cell cycle arrest in MCF-7 cells.Forma y color:Odour SolidLarotaxel dihydrate
CAS:Larotaxel dihydrate possesses antineoplastic activity.Fórmula:C45H57NO16Pureza:98%Forma y color:SolidPeso molecular:867.93TTBK1-IN-2
CAS:<p>TTBK1-IN-2, a TTBK1 inhibitor with IC50s of 0.24/4.22 µM, lowers TDP-43 phosphorylation in vitro and in mice.</p>Fórmula:C18H13ClN4OPureza:99.83%Forma y color:SoildPeso molecular:336.77Microtubule destabilizing agent-1
CAS:Compound 12b is a hydroxamic acid-based MDA with stable metabolism, high bioavailability, and strong antitumor properties.Fórmula:C22H26N4O4Forma y color:SolidPeso molecular:410.47THK5351 (R enantiomer)
CAS:THK5351 R enantiomer is an R enantiomer of THK5351.Fórmula:C18H18FN3O2Forma y color:SolidPeso molecular:327.35Tubulin polymerization-IN-47
CAS:Tubulin polymerization-IN-47 is a tubulin polymerization inhibitor and mitotic inhibitor with antitumor activity and inhibitory effects on neuroblastoma cancerFórmula:C22H21N3O3Pureza:99.64%Forma y color:SoildPeso molecular:375.42Deac-SS-Biotin
Deac-SS-Biotin is a potent antitumor compound that enters cells via biotin-mediated internalization.Forma y color:Odour SolidColchicine, N-deacetyl-10-thio-
CAS:Colchicine, N-deacetyl-10-thio- is a biochemical.Fórmula:C20H23NO4SForma y color:SolidPeso molecular:373.47MT189
CAS:<p>MT189 (Antiproliferative agent-14) inhibits tubulin polymerization (IC50 3.41 μM), arrests G2/M cell cycle, and is highly antiproliferative.</p>Fórmula:C21H18FN3O2Pureza:98.52%Forma y color:SoildPeso molecular:363.38Tubulin/PARP-IN-1
<p>Tubulin/PARP-IN-1 (compound 14) is a dual PARP-tubulin inhibitor with anti-endometrial cancer activity. It exhibits inhibitory concentration (IC50) values of 74 nM for PARP1, 109 nM for PARP2, and 1.4 μM for microtubules/tubulin. Tubulin/PARP-IN-1 induces apoptosis and autophagy, causing cell cycle arrest at the G2/M phase.</p>Fórmula:C19H13FO3Peso molecular:308.08487Anti-α-Tubulin Antibody, AF555 conjugate
Anti-α-Tubulin Antibody, AF555 conjugate, is a mouse-derived monoclonal antibody conjugated with the red fluorescent dye Alexa Fluor 555, designed for theForma y color:SolidTubulin polymerization-IN-53
Tubulin polymerization-IN-53 (compound 4b) serves as an inhibitor of β-tubulin polymerization and is capable of arresting the cell cycle at the G2/M stage.Forma y color:Odour SolidPlecstatin-1 hydrochloride
Plecstatin-1 hydrochloride, an organoeuropium-containing anticancer agent, selectively targets the scaffolding protein plectin within tumor spheroids [1].Forma y color:Odour SolidN-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide
CAS:N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide, a TAU cytotoxicity inhibitor, inhibits LDH leakage of M17-TAU P301L cells with EC50 of 325nMFórmula:C24H18ClN3OPureza:99.93%Forma y color:SoildPeso molecular:399.87Tubulin polymerization-IN-49
Tubulin polymerization-IN-49 (compound 12d), a potent inhibitor of tubulin polymerization, binds to the colchicine site on tubulin, subsequently inducing cellFórmula:C20H24O5Forma y color:SolidPeso molecular:344.4Pironetin
CAS:<p>Pironetin, from Streptomyces, inhibits microtubule polymerization and tumor growth, and causes cell cycle arrest.</p>Fórmula:C19H32O4Pureza:98%Forma y color:SolidPeso molecular:324.45PROTAC tubulin-Degrader-1
<p>PROTAC tubulin-Degrader-1 (Compound W13) functions as an inhibitor of PROTAC tubulin and exhibits anti-tumor activity against human lung cancer.</p>Forma y color:Odour SolidMicrotubule stabilizing agent-1
Compound 3l, a paclitaxel derivative known as Microtubule Stabilizing Agent-1, effectively enhances tubulin polymerization and demonstrates antitumor efficacy [Fórmula:C45H55NO13Forma y color:SolidPeso molecular:817.92Tubulin polymerization-IN-78
Tubulin polymerization-IN-78 (compound 10a) is an inhibitor of tubulin polymerization, with an IC50 value of 2.69 μM. It exhibits antiproliferative activity.Forma y color:Odour SolidAntiproliferative agent-66
Antiproliferative agent-66 (Compound B3) is an antiproliferative compound that induces apoptosis and causes cell cycle arrest. It demonstrates IC50 values ranging from 2.03 to 3.6 µM against SH-SY5Y neuroblastoma, HT-29 colorectal adenocarcinoma, and fibroblasts. Additionally, Antiproliferative agent-66 functions as a microtubule polymerization inhibitor with an IC50 of 0.79 µM.Fórmula:C18H15N3SForma y color:SolidPeso molecular:305.397Ceratamine A
CAS:<p>Ceratamine A, from Pseudoceratina sponge, is a cytotoxic, microtubule-stabilizing antimitotic alkaloid.</p>Fórmula:C17H16Br2N4O2Pureza:98%Forma y color:SolidPeso molecular:468.14Trimethylcolchicinic acid
CAS:Trimethylcolchicinic acid is an orally available colchicine analog that binds to tubulin and inhibits its polymerization into microtubules,potential antitumor.Fórmula:C19H21NO5Pureza:>99.99%Forma y color:SoildPeso molecular:343.37Anhydrovinblastine sulfate
Anhydrovinblastine sulfate is a monoterpene indole alkaloid that can be extracted from the leaves of Catharanthus roseus.Fórmula:C46H60N4O16S2Peso molecular:988.34457AADvac 1 TFA
AADvac 1 TFA is an active tau peptide vaccine utilized in Alzheimer's disease research. It is formed by conjugating the regulatory peptide 294KDNIKHVPGGGS305, which drives tau oligomerization, with keyhole limpet hemocyanin (KLH), and is formulated with aluminum hydroxide.Tubulin inhibitor 24
CAS:Tubulin inhibitor 24 is a potent inhibitor that can inhibit tubulin polymerization.Fórmula:C22H21N3O3Pureza:99.99%Forma y color:SolidPeso molecular:375.42Alestramustine
CAS:Alestramustine: a cancer drug that targets microtubules in estrogen receptor-positive cells, impeding cell division.Fórmula:C26H36Cl2N2O4Forma y color:SolidPeso molecular:511.48TNIR7-1A
CAS:<p>TNIR7-1A is a fused cycloheptatriene-BODIPY derivative that is optimized for near-infrared (NIR) imaging characteristics (Ex/Em = 600/774 nm in PBS) and exhibits high affinity and specificity for neurofibrillary tangles (NFT) in vitro. Additionally, TNIR7-1A can effectively penetrate the blood-brain barrier.</p>Fórmula:C23H20BF2N3Forma y color:SolidPeso molecular:387.23Dihydrocephalomannine
CAS:Dihydrocephalomannine is similar to paclitaxel, showing reduced cytotoxicity and tubulin binding.Fórmula:C45H55NO14Pureza:98%Forma y color:SolidPeso molecular:833.928Microtubule-associated protein tau (26-44)
<p>Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine.</p>Fórmula:C83H127N25O34SPureza:98%Forma y color:SolidPeso molecular:2051.11Tubulin polymerization-IN-51
Tubulin Polymerization-IN-51 (compound 7u) serves as a tubulin polymerization inhibitor, exhibiting an IC50 range of 2.55 - 17.89μM against SK-Mel-28 cells, andForma y color:Odour SolidTubulin polymerization-IN-44
<p>Tubulinpolymer-in-44 (compound 7w) effectively inhibits Tubulin with an IC50 value of 0.21 μM and induces apoptosis by arresting the G2/M phase, making it</p>Fórmula:C19H15Cl2N3O3SForma y color:SolidPeso molecular:436.31Indicine N-oxide
CAS:Indicine N-oxide (NSC 132319), a pyrrolizidine alkaloid, serves as an antitumor agent in pediatric cancer and solid tumors research.Fórmula:C15H25NO6Forma y color:SolidPeso molecular:315.37Bifidenone
CAS:Bifidenone is an effective tubulin polymerization inhibitor.Fórmula:C21H26O5Forma y color:SolidPeso molecular:358.43SPA107
CAS:SPA107 (Hemiasterlin methyl ester) is an analogue of Hemiasterlin. It inhibits tubulin polymerization, exhibiting antimitotic activity with an IC50 of 0.5 nM. SPA107 also shows cytotoxicity against p53 mutated MCF-7 cells, with an IC50 of 0.5 nM.Fórmula:C31H48N4O4Forma y color:SolidPeso molecular:540.747-Epi-docetaxel
CAS:7-Epi-10-oxo-docetaxel (7-Epitaxotere) is a impurity of docetaxel.Fórmula:C43H53NO14Pureza:98%Forma y color:SolidPeso molecular:807.88Epothilone F
CAS:Epothilone F, an active metabolite of Epothilone D with a hydroxymethyl on thiazole, disrupts cell division, shows promise over taxanes, and is water-soluble.Fórmula:C27H41NO7SForma y color:SolidPeso molecular:523.68RI-AG03
RI-AG03 is an orally active peptide inhibitor capable of crossing the blood-brain barrier, targeting Tau aggregation. It effectively inhibits Tau aggregation in both in vivo and in vitro models, improving associated neurodegenerative and behavioral phenotypes. RI-AG03 is applicable in research on Tauopathies such as Alzheimer's disease.Fórmula:C104H189N49O22Forma y color:SolidPeso molecular:2477.93Cy5-Paclitaxel
Cy5-Paclitaxel is a Cy5-labeled paclitaxel conjugate. Cy5 is a cyanine dye (with an approximate wavelength of 662 nm) utilized in molecular labeling and microscopy imaging. Paclitaxel stabilizes tubulin polymerization, causing mitotic arrest and apoptotic death. It also induces autophagy.Fórmula:C93H104N4O16Peso molecular:1533.84Aβ-IN-1 TFA
<p>Aβ-IN-1 TFA inhibits and reverses different types of protein aggregation.</p>Fórmula:C37H50F3NO2Pureza:99.82%Forma y color:SoildPeso molecular:597.79OncoFAP-GlyPro-MMAE
CAS:OncoFAP-GlyPro-MMAE is a FAP small molecule-drug conjugate (SMDC) with an IC50 of 0.49 nM. It is composed of the FAP ligand OncoFAP, a microtubule inhibitor (MMAE), and a linker. OncoFAP-GlyPro-MMAE can be utilized in cancer research, including studies on renal cancer.Fórmula:C102H141F2N19O27SForma y color:SolidPeso molecular:2135.38Tubulin inhibitor 21
Compound 6f, a chalcone-melatonin hybrid, is a potent tubulin inhibitor with IC50=0.26μM in SW480 cells, less toxic to non-cancer cells.Fórmula:C28H25N3O4SForma y color:SolidPeso molecular:499.58Vinflunine Tartrate
CAS:Vinflunine Tartrate, a uniquely fluorinated vinca alkaloid, exhibits mitotic-arresting and tubulin-interacting properties.Fórmula:C45H54F2N4O8·xC4H6O6Pureza:98%Forma y color:SolidPeso molecular:967.02PM050489
CAS:PM050489, a polyketone inhibitor from Lithoplocamia lithistoides, halts mitosis at 26.4 nM IC50 and aids cancer research.Fórmula:C31H44ClN3O7Forma y color:SolidPeso molecular:606.15Anticancer agent 270
Anticanceragent 270 (Compound 8e) is a microtubule protein inhibitor with an IC50 of 1.02 μM against MCF-7 breast cancer cells. It exerts significant antiproliferative activity on breast cancer cells through a dual mechanism of inducing apoptosis and destabilizing microtubules. Anticanceragent 270 is useful for cancer research.Forma y color:Odour SolidALB-109564 dihydrochloride
CAS:<p>ALB-109564 dihydrochloride: Semi-synthetic, vinblastine-derived, microtubule inhibitor, arrests tumor cells in G2/M phase.</p>Fórmula:C47H62Cl2N4O9SPureza:98%Forma y color:SolidPeso molecular:929.99Tubulin polymerization-IN-50
Tubulin Polymerization-IN-50 (compound 7n) serves as an inhibitor of tubulin polymerization, exhibiting an IC50 of 5.05 μM in SK-Mel-28 cells and inducing cellFórmula:C24H20FN3O3Forma y color:SolidPeso molecular:417.43T-808
CAS:T-808 is a tau tracer which may be used in radiographic labeling of Tau aggregates during Alzheimer's disease.Fórmula:C17H19FN4Forma y color:SolidPeso molecular:298.36KGP591
KGP591, a tubulin polymerization inhibitor with an IC50 of 0.57 µM, effectively induces G2/M arrest, inhibits cell migration, and disrupts microtubule structureFórmula:C24H21NO5Forma y color:SolidPeso molecular:403.4310-Oxo Docetaxel
CAS:10-Oxo Docetaxel is a Docetaxel intermediate having remarkable antitumor properties.Fórmula:C43H51NO14Pureza:98%Forma y color:SolidPeso molecular:805.874Combretastatin A-1 phosphate tetrasodium
CAS:OXi-4503, a prodrug of Combretastatin A-1, disrupts tubulin, inhibits Wnt/β-catenin and AKT, and has anti-tumor/vascular effects.Fórmula:C18H18Na4O12P2Forma y color:SolidPeso molecular:580.24Tubulin inhibitor 36
Tubulin Inhibitor 36 (Compound 10) serves as a potent novel inhibitor of tubulin polymerization, which consequently induces apoptosis in glioblastoma cells,Fórmula:C16H13ClN6SForma y color:SolidPeso molecular:356.83Tubulin polymerization-IN-48
Tubulin polymerization-IN-48 (Compound 4k) is an inhibitor of tubulin polymerization, moderately disrupting the microtubule network.Fórmula:C20H15Cl2N3OForma y color:SolidPeso molecular:384.26Tubulin inhibitor 37
Tubulin Inhibitor 37 (Compound 12) effectively impedes tubulin aggregation (IC50 = 1.3 µM) and demonstrates antiproliferative activity against human tumor cellFórmula:C16H10Cl2N6OForma y color:SolidPeso molecular:373.2Modified MMAF
CAS:Modified MMAF, an ADC cytotoxin, aids in ADC synthesis for targeted cancer research.Fórmula:C45H73N7O8Forma y color:SolidPeso molecular:840.1Tubulin polymerization-IN-46
Tubulin polymerization-IN-46 (compound 9q) is a microtubule/tubulin inhibitor that impedes tubulin polymerization, induces apoptosis, and arrests MCF-7 breastFórmula:C22H25NO6Forma y color:SolidPeso molecular:399.4420-O-Demethyl-AP3
CAS:<p>20-O-Demethyl-AP3, a derivative of the microtubule-inhibiting antitumor agent Ansamitocin P-3, is a secondary metabolite.</p>Fórmula:C31H41ClN2O9Forma y color:SolidPeso molecular:621.12Phomopsinamine
CAS:Phomopsinamine, a phomopsin A derivative, hampers microtubule assembly in sheep brain tubulin (IC50: 0.53-0.59 μM).Fórmula:C32H43ClN6O8Forma y color:SolidPeso molecular:675.17Tubulin inhibitor 38
<p>Tubulin Inhibitor 38 (Compound 14), a tetrazole-based agent, demonstrates significant antiproliferative effects by inducing mitotic arrest and blocking the cell</p>Fórmula:C17H13ClN6OSForma y color:SolidPeso molecular:384.84Anticancer agent 139
Compound 6h (Anticancer Agent 139) exhibits potent anticancer activity, engaging in a π-cationic interaction with Lys352 of Tubulin and demonstrating highFórmula:C16H12F3N3OForma y color:SolidPeso molecular:319.28Phomopsin A
CAS:Phomopsin A is a cyclic hexapeptide mycotoxin isolated from the fungus Phomopsis leptostomiformis.Fórmula:C36H45ClN6O12Pureza:98%Forma y color:SolidPeso molecular:789.23KIF18A-IN-2
CAS:<p>KIF18A-IN-2 is an inhibitor of mitotic kinesin Kif18A with IC50 of 28 nM and can be used in studies about chromosomal instability-associated vulnerabilities.</p>Fórmula:C25H34N4O5S2Pureza:99.64%Forma y color:SolidPeso molecular:534.697-Epi-10-oxo-docetaxel
CAS:7-Epi-10-oxo-docetaxel (Docetaxel Impurity 2) is an impurity of docetaxel detected by HPLC.Fórmula:C43H51NO14Pureza:98%Forma y color:SolidPeso molecular:805.86Vinzolidine
CAS:Vinzolidine is a semi-synthetic vinca alkaloid. It exerts cytotoxic effects on tumor cells by inhibiting cell division through disruption of tubulin polymerization. Vinzolidine can be utilized in research to investigate synergy with other chemotherapy or biotherapy drugs, as well as cancer cell tolerance or resistance, and to explore strategies to overcome these challenges.Fórmula:C48H58ClN5O9Forma y color:SolidPeso molecular:884.46Tubulin inhibitor 50
Tubulin inhibitor 50 (compound 07) is a microtubule protein inhibitor that enhances mitochondrial reactive oxygen species levels. It exhibits anticancer activity in HeLa cells with an IC50 value of 0.46 μM, while showing low toxicity in normal cell lines.Fórmula:C16H10ClFN2O2Forma y color:SolidPeso molecular:316.04148Tubulin inhibitor 45
Tubulin inhibitor 45 (compound 5) functions as an inhibitor of the active site of tubulin. It exhibits IC50 values of 11 μM for MCF7 cancer cells and 13 μM for HePG2 cancer cells.Fórmula:C19H18N2O2SPeso molecular:338.1089PhosTAC7
CAS:PhosTAC7 successfully induced ternary protein complex formation of Halo-FOXO3a in a dose-dependent manner.Fórmula:C58H87ClN2O17Pureza:98.96%Forma y color:SolidPeso molecular:1119.77Tirbanibulin dihydrochloride
CAS:Tirbanibulin is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).Fórmula:C26H31Cl2N3O3Pureza:98%Forma y color:SolidPeso molecular:504.45Trifluralin
CAS:<p>Trifluralin (Treflan) is an agricultural herbicide with mild toxicity. Trifluralin is a novel pollutant that can interfere with mitochondrial respiration.</p>Fórmula:C13H16F3N3O4Pureza:99.84%Forma y color:Yellow-Orange Crystalline SolidPeso molecular:335.28Ombrabulin hydrochloride
CAS:<p>Ombrabulin hydrochloride is a synthetic, selective CA-4 phosphate ester or derivative of Ombrabulin to disrupt the tubulin cytoskeleton of endothelial cells and</p>Fórmula:C21H27ClN2O6Pureza:98%Forma y color:SolidPeso molecular:438.9colchiceine
CAS:colchiceine has a wide range of applications in life science related research.Fórmula:C21H23NO6Pureza:99.38%Forma y color:SolidPeso molecular:385.41BSc3094
CAS:BSc3094 is a potent Tau aggregation inhibitor that demonstrates the potential for Alzheimer's disease (AD) research.Fórmula:C17H12N6O3SForma y color:SolidPeso molecular:380.38Amiprofos methyl
CAS:Amiprofos methyl (BAY-NTN 6867) is an organophosphorus herbicide that specifically and competitively inhibits microtubule polymerization in plant cells.Fórmula:C11H17N2O4PSPureza:99.66%Forma y color:SolidPeso molecular:304.30Oryzalin
CAS:Oryzalin is a selective pre-emergence herbicide belonging to the dinitroaniline class, which exerts its effect by inhibiting cell division in weeds.Fórmula:C12H18N4O6SPureza:99.86%Forma y color:SolidPeso molecular:346.36TTBK1-IN-1
CAS:TTBK1-IN-1 (compound 31) is a potent and selective TTBK1 inhibitor with CNS penetration that inhibits tau phosphorylation , Alzheimer's disease.Fórmula:C18H19N5O2Forma y color:SolidPeso molecular:337.38Avanbulin
CAS:Avanbulin hinders tubulin polymerization, has unique antitumor properties, and is effective against various human tumors at low concentrations.Fórmula:C20H17N7O2Forma y color:SolidPeso molecular:387.39TN-16
CAS:TN-16 is a microtubule polymerization inhibitor (IC50 :0.4-1.7 μM)Fórmula:C19H18N2O2Pureza:99.54%Forma y color:SolidPeso molecular:306.36Vindesine sulfate
CAS:Vindesine sulfate, a vinca alkaloid derived from vinblastine, binds to spindle microtubules, causing cell death.Fórmula:C43H57N5O11SPureza:97.51%Forma y color:Amorphous SolidPeso molecular:852N-Phenylbenzylamine
CAS:A series of N-Phenylbenzylamine (Benzenemethanamine) as potential cytotoxic and antimitotic agents acting by inhibition of tubulin polymerizationFórmula:C13H13NPureza:98.75%Forma y color:Colorless To Pale Yellow Crystalline PowderPeso molecular:183.25
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