Asociado a microtúbulos
Los inhibidores de proteínas asociadas a microtúbulos se dirigen a proteínas que interactúan con los microtúbulos, los componentes estructurales del citoesqueleto de la célula, esenciales para la división celular. Estas proteínas regulan la estabilidad y la dinámica de los microtúbulos durante la mitosis. Inhibir las proteínas asociadas a microtúbulos puede interrumpir la función de los microtúbulos, lo que lleva al arresto del ciclo celular y la apoptosis, particularmente en células cancerosas de rápida división. Estos inhibidores se utilizan ampliamente en la investigación del cáncer y el desarrollo de fármacos. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteínas asociadas a microtúbulos de alta calidad para apoyar su investigación en división celular, dinámica del citoesqueleto y terapia contra el cáncer.
Se han encontrado 283 productos de "Asociado a microtúbulos"
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10-Oxo Docetaxel
CAS:10-Oxo Docetaxel is a Docetaxel intermediate having remarkable antitumor properties.Fórmula:C43H51NO14Pureza:98%Forma y color:SolidPeso molecular:805.874Cys-McMMAF
CAS:Cys-McMMAF, a microtubule-disrupting agent linked to an anti-5T4 antibody, shows antitumor effects in mouse models.Fórmula:C52H83N7O13SForma y color:SolidPeso molecular:1046.32Diminutol
CAS:Diminutol, a purine derivative, inhibits NQO1 (Ki=1.72μM), affects tubulin polymerization, and disrupts mitosis at 50μM without impacting Cdk1 or actin.Fórmula:C19H26N6OSForma y color:SolidPeso molecular:386.51Anti-α-Tubulin Antibody, AF555 conjugate
Anti-α-Tubulin Antibody, AF555 conjugate, is a mouse-derived monoclonal antibody conjugated with the red fluorescent dye Alexa Fluor 555, designed for theForma y color:SolidTubulin inhibitor 21
Compound 6f, a chalcone-melatonin hybrid, is a potent tubulin inhibitor with IC50=0.26μM in SW480 cells, less toxic to non-cancer cells.Fórmula:C28H25N3O4SForma y color:SolidPeso molecular:499.58ALB-109564 dihydrochloride
CAS:ALB-109564 dihydrochloride: Semi-synthetic, vinblastine-derived, microtubule inhibitor, arrests tumor cells in G2/M phase.Fórmula:C47H62Cl2N4O9SPureza:98%Forma y color:SolidPeso molecular:929.99Microtubule-associated protein tau (26-44)
<p>Microtubule-associated protein tau (26-44) is a synthetic peptide with an amino group conjugated to glutamine and a carboxyl group conjugated to lysine.</p>Fórmula:C83H127N25O34SPureza:98%Forma y color:SolidPeso molecular:2051.11T-808
CAS:T-808 is a tau tracer which may be used in radiographic labeling of Tau aggregates during Alzheimer's disease.Fórmula:C17H19FN4Forma y color:SolidPeso molecular:298.36KGP591
KGP591, a tubulin polymerization inhibitor with an IC50 of 0.57 µM, effectively induces G2/M arrest, inhibits cell migration, and disrupts microtubule structureFórmula:C24H21NO5Forma y color:SolidPeso molecular:403.43Combretastatin A-1 phosphate tetrasodium
CAS:OXi-4503, a prodrug of Combretastatin A-1, disrupts tubulin, inhibits Wnt/β-catenin and AKT, and has anti-tumor/vascular effects.Fórmula:C18H18Na4O12P2Forma y color:SolidPeso molecular:580.24Vinflunine Tartrate
CAS:Vinflunine Tartrate, a uniquely fluorinated vinca alkaloid, exhibits mitotic-arresting and tubulin-interacting properties.Fórmula:C45H54F2N4O8·xC4H6O6Pureza:98%Forma y color:SolidPeso molecular:967.02Ref: TM-T6722
2mgA consultar5mgA consultar10mgA consultar25mgA consultar50mgA consultar1mL*10mM (DMSO)A consultarTubulin polymerization-IN-78
Tubulin polymerization-IN-78 (compound 10a) is an inhibitor of tubulin polymerization, with an IC50 value of 2.69 μM. It exhibits antiproliferative activity.Forma y color:Odour SolidPM050489
CAS:PM050489, a polyketone inhibitor from Lithoplocamia lithistoides, halts mitosis at 26.4 nM IC50 and aids cancer research.Fórmula:C31H44ClN3O7Forma y color:SolidPeso molecular:606.15Phomopsinamine
CAS:Phomopsinamine, a phomopsin A derivative, hampers microtubule assembly in sheep brain tubulin (IC50: 0.53-0.59 μM).Fórmula:C32H43ClN6O8Forma y color:SolidPeso molecular:675.17Tubulin polymerization-IN-46
Tubulin polymerization-IN-46 (compound 9q) is a microtubule/tubulin inhibitor that impedes tubulin polymerization, induces apoptosis, and arrests MCF-7 breastFórmula:C22H25NO6Forma y color:SolidPeso molecular:399.44Phomopsin A
CAS:Phomopsin A is a cyclic hexapeptide mycotoxin isolated from the fungus Phomopsis leptostomiformis.Fórmula:C36H45ClN6O12Pureza:98%Forma y color:SolidPeso molecular:789.2320-O-Demethyl-AP3
CAS:20-O-Demethyl-AP3, a derivative of the microtubule-inhibiting antitumor agent Ansamitocin P-3, is a secondary metabolite.Fórmula:C31H41ClN2O9Forma y color:SolidPeso molecular:621.12Modified MMAF
CAS:Modified MMAF, an ADC cytotoxin, aids in ADC synthesis for targeted cancer research.Fórmula:C45H73N7O8Forma y color:SolidPeso molecular:840.1Cy5-Paclitaxel
Cy5-Paclitaxel is a Cy5-labeled paclitaxel conjugate. Cy5 is a cyanine dye (with an approximate wavelength of 662 nm) utilized in molecular labeling and microscopy imaging. Paclitaxel stabilizes tubulin polymerization, causing mitotic arrest and apoptotic death. It also induces autophagy.Fórmula:C93H104N4O16Peso molecular:1533.84ER-076349
CAS:ER-076349 is a microtubule polymerization inhibitor that induces G2-M cell cycle arrest and disrupts mitotic spindles. This compound inhibits the growth of cancer cells and suppresses tumor growth in various human tumor xenograft mouse models. Additionally, ER-076349 is an analog of Halichondrin B.Fórmula:C40H58O12Peso molecular:730.88
