Asociado a microtúbulos
Los inhibidores de proteínas asociadas a microtúbulos se dirigen a proteínas que interactúan con los microtúbulos, los componentes estructurales del citoesqueleto de la célula, esenciales para la división celular. Estas proteínas regulan la estabilidad y la dinámica de los microtúbulos durante la mitosis. Inhibir las proteínas asociadas a microtúbulos puede interrumpir la función de los microtúbulos, lo que lleva al arresto del ciclo celular y la apoptosis, particularmente en células cancerosas de rápida división. Estos inhibidores se utilizan ampliamente en la investigación del cáncer y el desarrollo de fármacos. En CymitQuimica, ofrecemos una amplia gama de inhibidores de proteínas asociadas a microtúbulos de alta calidad para apoyar su investigación en división celular, dinámica del citoesqueleto y terapia contra el cáncer.
Se han encontrado 284 productos de "Asociado a microtúbulos"
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Phomopsin A
CAS:Phomopsin A is a cyclic hexapeptide mycotoxin isolated from the fungus Phomopsis leptostomiformis.Fórmula:C36H45ClN6O12Pureza:98%Forma y color:SolidPeso molecular:789.23Tubulin polymerization-IN-78
Tubulin polymerization-IN-78 (compound 10a) is an inhibitor of tubulin polymerization, with an IC50 value of 2.69 μM. It exhibits antiproliferative activity.Forma y color:Odour SolidPironetin
CAS:Pironetin, from Streptomyces, inhibits microtubule polymerization and tumor growth, and causes cell cycle arrest.Fórmula:C19H32O4Pureza:98%Forma y color:SolidPeso molecular:324.45Antiproliferative agent-66
Antiproliferative agent-66 (Compound B3) is an antiproliferative compound that induces apoptosis and causes cell cycle arrest. It demonstrates IC50 values ranging from 2.03 to 3.6 µM against SH-SY5Y neuroblastoma, HT-29 colorectal adenocarcinoma, and fibroblasts. Additionally, Antiproliferative agent-66 functions as a microtubule polymerization inhibitor with an IC50 of 0.79 µM.Fórmula:C18H15N3SForma y color:SolidPeso molecular:305.397Ceratamine A
CAS:<p>Ceratamine A, from Pseudoceratina sponge, is a cytotoxic, microtubule-stabilizing antimitotic alkaloid.</p>Fórmula:C17H16Br2N4O2Pureza:98%Forma y color:SolidPeso molecular:468.14Breast cancer targeting peptide 18-4
CAS:Breastcancertargeting peptide 18–4 is a keratin 1 (KRT1) receptor-targeting peptide with a dissociation constant (Kd) of 0.98 μM. Its amino acid sequence is WxEAAYQrFL, and it is an analogue of the P160 peptide. When covalently bonded with the anticancer peptide MccJ25, it significantly enhances MccJ25 uptake in breast cancer cells and boosts its anticancer efficacy. The IC50 values for this covalent compound are 14.2, 20, and 25 μM against MCF-7, MDA-MB-435, and MDA-MB-435-MDR, respectively.Fórmula:C63H89N15O15Peso molecular:1296.47Diminutol
CAS:Diminutol, a purine derivative, inhibits NQO1 (Ki=1.72μM), affects tubulin polymerization, and disrupts mitosis at 50μM without impacting Cdk1 or actin.Fórmula:C19H26N6OSForma y color:SolidPeso molecular:386.51PhosTAC7
CAS:PhosTAC7 successfully induced ternary protein complex formation of Halo-FOXO3a in a dose-dependent manner.Fórmula:C58H87ClN2O17Pureza:98.96%Forma y color:SolidPeso molecular:1119.77Tirbanibulin dihydrochloride
CAS:Tirbanibulin is an inhibitor of Src that targets the peptide substrate site of Src (GI50: 9-60 nM in cancer cell lines).Fórmula:C26H31Cl2N3O3Pureza:98%Forma y color:SolidPeso molecular:504.45Ombrabulin hydrochloride
CAS:<p>Ombrabulin hydrochloride is a synthetic, selective CA-4 phosphate ester or derivative of Ombrabulin to disrupt the tubulin cytoskeleton of endothelial cells and</p>Fórmula:C21H27ClN2O6Pureza:98%Forma y color:SolidPeso molecular:438.9Trifluralin
CAS:<p>Trifluralin (Treflan) is an agricultural herbicide with mild toxicity. Trifluralin is a novel pollutant that can interfere with mitochondrial respiration.</p>Fórmula:C13H16F3N3O4Pureza:99.84%Forma y color:Yellow-Orange Crystalline SolidPeso molecular:335.28colchiceine
CAS:colchiceine has a wide range of applications in life science related research.Fórmula:C21H23NO6Pureza:99.38%Forma y color:SolidPeso molecular:385.41TTBK1-IN-1
CAS:TTBK1-IN-1 (compound 31) is a potent and selective TTBK1 inhibitor with CNS penetration that inhibits tau phosphorylation , Alzheimer's disease.Fórmula:C18H19N5O2Forma y color:SolidPeso molecular:337.38Amiprofos methyl
CAS:Amiprofos methyl (BAY-NTN 6867) is an organophosphorus herbicide that specifically and competitively inhibits microtubule polymerization in plant cells.Fórmula:C11H17N2O4PSPureza:99.66%Forma y color:SolidPeso molecular:304.30BSc3094
CAS:BSc3094 is a potent Tau aggregation inhibitor that demonstrates the potential for Alzheimer's disease (AD) research.Fórmula:C17H12N6O3SForma y color:SolidPeso molecular:380.38Avanbulin
CAS:Avanbulin hinders tubulin polymerization, has unique antitumor properties, and is effective against various human tumors at low concentrations.Fórmula:C20H17N7O2Forma y color:SolidPeso molecular:387.39Oryzalin
CAS:Oryzalin is a selective pre-emergence herbicide belonging to the dinitroaniline class, which exerts its effect by inhibiting cell division in weeds.Fórmula:C12H18N4O6SPureza:99.86%Forma y color:SolidPeso molecular:346.36Valecobulin
CAS:Valecobulin is a potent β-tubulin polymerization inhibitor. Valecobulin is a valine prodrug of (S516) and an avascular disrupting compound.Fórmula:C26H28N6O5SPureza:98%Forma y color:SolidPeso molecular:536.6Vindesine sulfate
CAS:Vindesine sulfate, a vinca alkaloid derived from vinblastine, binds to spindle microtubules, causing cell death.Fórmula:C43H57N5O11SPureza:97.51%Forma y color:Amorphous SolidPeso molecular:8524-Isopropoxybenzoic acid
CAS:4-Isopropoxybenzoic acid (AI3 12104) is a Centromere-Associated Protein E inhibitor.Fórmula:C10H12O3Pureza:99.88%Forma y color:White To Off-White PowderPeso molecular:180.2
