c-Myc

Saxagliptin is a selective and reversible DPP4 inhibitor (IC50: 26 nM; Ki: 1.3 nM).

FIDAS-3 effectively competes against S-adenosylmethionine (SAM) for MAT2A binding. FIDAS-3 has anticancer activities. FIDAS-3 is …

MYCMI-6 is a potent and selective inhibitor of endogenous MYC:MAX protein interactions,reduces proliferation and induces …

KJ Pyr 9 is an MYC inhibitor (Kd: 6.5 nM in vitro assay).

FIDAS-5 effectively competes against S-adenosylmethionine (SAM) for MAT2A binding. FIDAS-5 has anticancer activities. FIDAS-5 is …

MYCi975 is an orally active inhibitor of MYC.

MYCi361 is an inhibitor of MYC (binding to MYC with Kd of 3.2 μM).

Cereblon modulator 1 is a cereblon (CRBN) E3 ligase modulator. It specifically binds to CRBN, …

APTO-253 inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in …

Ceramides Mixture, an endogenous ceramide, consists of hydroxy and non-hydroxy fatty acid-containing ceramides. It is …

Moracin C and moracin D, new phytoalexins from diseased mulberry, are antifungal compounds. Moracin may …

VPC-70063 is an inhibitor of c-Myc-MAX. VPC-70063 exhibits Myc-Max transcriptional activity inhibition of 106% with …

Aaptamine functions as a proteasome inhibitor, it activates p21 promoter in a p53-independent manner.

Sanggenol L shows higher cytotoxicity against human oral tumor cell lines (HSC-2 and HSG) than …

Coronarin D shows promising antifungal activity against C. albicans in vitro, the minimum inhibitory concentration …

Moracin treatment can inhibit the double 12-O-tetradecanoylphorbol 13-acetate (TPA) treatment-induced morphological changes reflecting inflammatory response, …

10074-G5 is an inhibitor of c-Myc-Max dimerization.

Mycro 3 is potent and selective for c-Myc in whole cell assays.

10058-F4 is a cell-permeable thiazolidinone that specifically inhibits the c-Myc-Max interaction and prevents transactivation of …

NNK is a procarcinogen and a major tobacco-specific toxicant. It inhibits the expression of lysyl …

Saxagliptin is a selective and reversible DPP4 inhibitor with IC50 of 26 nM.

Nicotinamide N-oxide is recognized as an in vivo metabolite of nicotinamide which is a precurser …

Lusianthridin is a natural product from Dendrobium venustum. Lusianthridin exhibits anti-migratory property at nontoxic concentrations. …

Mollugin may be a JAK2 inhibitor and inhibits LPS-induced inflammatory responses by blocking the activation …

10074-A4 is a c-Myc binding compound that associates with c-Myc370-409 and behaves like a “ligand …

Artemisitene is the oxidized form of Artemisinin and is an antimalarial agent. Artemisinin precursors are …

NY2267 is a disruptor of Myc-Max interaction, with an IC50 of 36.5 μM.

1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.

MDK6620 is an inhibitor of the oncofetal mRNA-binding protein IMP1 (IC50 = 5 μM for …

Idarubicin HCl, a hydrochloride salt form of Idarubicin, is a DNA topoisomerase II (topo II) …

EN4 MYC inhibitor is a covalent ligand that targets cysteine 171 (C171) of MYC. It …

ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition …

10-Hydroxycamptothecin is a DNA topoisomerase I inhibitor, utilized as a clinical therapy agent against hepatoma.

KSI-3716 is an inhibitor of c-Myc.

sAJM589 is a Myc inhibitor(IC50: 1.8 μM).

CBP/EP300-IN-2 is an inhibitor of CBP/EP300 (IC50s: 1.07 nM and 5.96 nM for CBP/HTRF and …