PKC
Los inhibidores de la proteína quinasa C (PKC) se dirigen a la familia de quinasas serina/treonina PKC, que están involucradas en una amplia gama de procesos celulares, incluidos la regulación del ciclo celular, la apoptosis y la diferenciación. La PKC desempeña un papel clave en las vías de transducción de señales que influyen en la proliferación y supervivencia celular. Inhibir la PKC puede provocar cambios en la progresión del ciclo celular, lo que hace que estos inhibidores sean valiosos en la investigación relacionada con el cáncer, la neurobiología y las enfermedades cardiovasculares. En CymitQuimica, ofrecemos una selección diversa de inhibidores de PKC de alta calidad para apoyar su investigación en transducción de señales, regulación del ciclo celular y desarrollo terapéutico.
Se han encontrado 126 productos de "PKC"
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[Ala113]MBP(104-118)
CAS:Synthetic peptide analog of bovine myelin basic protein (MBP). Non-competitive inhibitor of PKC (IC50 = 28 - 62 mM).Fórmula:C67H104N20O19Pureza:98%Forma y color:SolidPeso molecular:1493.68N-Myristoyl-Lys-Arg-Thr-Leu-Arg
CAS:N-Myristoyl-Lys-Arg-Thr-Leu-Arg: PKC inhibitor, IC50=75μM, blocks IL-2 in Jurkat cells.Fórmula:C42H82N12O8Forma y color:SolidPeso molecular:883.18[Ala107]MBP(104-118)
CAS:Synthetic peptide analog of bovine myelin basic protein (MBP). Non-competitive inhibitor of PKC (IC50 = 46 - 145 mM).Fórmula:C67H104N20O19Pureza:98%Forma y color:SolidPeso molecular:1493.68Neuropeptide DF2
CAS:Neuropeptide DF2 is an FMRFamide-related neuropeptide from crayfish.Fórmula:C44H67N15O10Pureza:98%Forma y color:SolidPeso molecular:966.1PKC β pseudosubstrate TFA
PKC β pseudosubstrate TFA is a selective cell-permeable inhibitor of PKC [1] .Fórmula:C179H295F3N62O40S3Forma y color:SolidPeso molecular:4108.84PKC-ε translocation inhibitor peptide
PKC-ε Translocation Inhibitor Peptide is a selective modulator that controls the FcγR-mediated internalization rate of opsonized beads without affecting FcαRPureza:98%Forma y color:Odour Solidpep2-EVKI
CAS:Peptide inhibits GluA2-PICK1 binding, sparing GluA2-GRIP/ABP interaction and LTD, without boosting AMPA current.Fórmula:C62H95N13O19Pureza:98%Forma y color:SolidPeso molecular:1326.51Sangivamycin
CAS:Sangivamycin (NSC-65346) inhibits PKC (Ki=10μM) and hinders growth in various human cancers.
Fórmula:C12H15N5O5Pureza:99.85%Forma y color:SolidPeso molecular:309.28ε-V1-2, Cys-conjugated
Epsilon-V1-2, a Cys-conjugated, is a biologically active peptide known as the εPKC-specific inhibitor.Fórmula:C40H70N10O14SPureza:98%Forma y color:SolidPeso molecular:947.11PKCδ Peptide Substrate
CAS:PKCδ Peptide Substrate is a highly specific substrate for the δ-type of Protein kinase C, composed of a sequence that mirrors murine eEF-1α (422-443) andFórmula:C109H191N35O29SForma y color:SolidPeso molecular:2487.97Protein kinase C α peptide TFA
CAS:Protein Kinase C (alpha) Peptide (TFA) is a PKC-α-associated peptide functioning as a lipid-dependent serine/threonine protein kinase.Fórmula:C68H115F3N24O26SForma y color:SolidPeso molecular:1773.85NPC-15437 dihydrochloride
CAS:NPC-15437 dihydrochloride is a PKC inhibitor blocking enzyme activity and phorbol ester binding, selective over other kinases, in cellular signaling research.Fórmula:C25H52Cl2N4O2Forma y color:SolidPeso molecular:511.62PKCβII Peptide Inhibitor I
CAS:PKCβII Peptide Inhibitor I, a specific PKCβII inhibitor, exhibits cardioprotective properties in a rat cardiac ischemia/reperfusion injury model and mitigatesFórmula:C61H94N12O19Pureza:98%Forma y color:SolidPeso molecular:1299.47K-252b
CAS:K-252b, an indolocarbazole derived from the actinomycete Nocardiopsis, functions as a protein kinase C (PKC) inhibitor.
Fórmula:C26H19N3O5Pureza:98%Forma y color:Ready-To-Use SolutionPeso molecular:453.45LY 379196
LY 379196, a potent PKC-β inhibitor (IC 50: 50 nM for PKC βI and 30 nM for PKC βII), effectively suppresses the proliferation of bovine retinal microvascular endothelial cells (BREC) induced by VEGF, IGF-1, and bFGF. This compound serves as an antiproliferative agent for proliferative retinopathy.Fórmula:C30H34N4O5SForma y color:SolidPeso molecular:562.68Protein kinase inhibitor H-7 dihydrochloride
CAS:Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor.Fórmula:C14H19Cl2N3O2SPureza:99.81%Forma y color:White Crystalline SolidPeso molecular:364.29(±)-1,2-Diolein
CAS:(±)-1,2-Diolein (1,2-Dioleoyl-rac-glycerol) (1,2-Dioleoyl-rac-glycerol) is a PKC activator. (±)-1,2-Diolein could increases myotubes Ca 2+ influx.Fórmula:C39H72O5Forma y color:SolidPeso molecular:620.99PKC-θ inhibitor
CAS:PKC-theta inhibitor is PKC-θinhibitor, with an IC50 of 12 nM.Fórmula:C20H25F3N6O3Pureza:99.46%Forma y color:SolidPeso molecular:454.45Ref: TM-T5423
1mg101,00€5mg236,00€10mg313,00€25mg442,00€50mg580,00€100mg893,00€200mg1.198,00€1mL*10mM (DMSO)259,00€Staurosporine
CAS:Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) against PKC, PKA, c-FgrFórmula:C28H26N4O3Pureza:99.24% - 99.82%Forma y color:Off-White PowderPeso molecular:466.53Ref: TM-T6680
1mg58,00€2mg82,00€5mg92,00€10mg138,00€25mg234,00€50mg380,00€100mg565,00€500mg1.215,00€1mL*10mM (DMSO)103,00€Bisindolylmaleimide V
CAS:Bisindolylmaleimide V, a bisindolylmaleimide derivative, is an inactive of a kinase inhibitor.Fórmula:C21H15N3O2Pureza:90%Forma y color:Red SolidPeso molecular:341.36
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