HSP
Los inhibidores de proteínas de choque térmico (HSP) se dirigen a las HSP, una familia de chaperonas moleculares que asisten en el plegamiento de proteínas, la estabilidad y la protección contra daños inducidos por el estrés. Las HSP suelen estar sobreexpresadas en células cancerosas, ayudándolas a sobrevivir en condiciones estresantes como la hipoxia y la quimioterapia. Inhibir las HSP puede interrumpir estos mecanismos de protección, lo que conduce a la muerte celular. Por lo tanto, los inhibidores de HSP son valiosos en la terapia contra el cáncer y en la investigación de respuestas al estrés. En CymitQuimica, ofrecemos una amplia gama de inhibidores de HSP de alta calidad para apoyar su investigación en homeostasis de proteínas, respuestas al estrés y oncología.
Se han encontrado 169 productos de "HSP"
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MAL3-101
CAS:<p>MAL3-101 is a molecular chaperone inhibitor of heat shock protein 70 (Hsp 70).</p>Fórmula:C54H66N4O10Forma y color:SolidPeso molecular:931.12HS-27
CAS:<p>HS-27 is a fluorescently-tethered inhibitor of Hsp90 with SNX-5422 tethered via a PEG linker to a fluorescein isothiocyanate or FITC.</p>Fórmula:C52H60N6O12SPureza:97.09%Forma y color:SolidPeso molecular:993.1317-DMAP-GA
CAS:<p>17-DMAP-GA, a Geldanamycin analogue, acts as an HSP90 inhibitor, leading to cell cycle abnormalities.</p>Fórmula:C33H50N4O8Forma y color:SolidPeso molecular:630.783Alvespimycin TFA
<p>Alvespimycin (17-DMAG) TFA is a potent inhibitor of Hsp90, binding with an EC50 of 62 ± 29 nM.</p>Fórmula:C34H49F3N4O10Forma y color:SolidPeso molecular:730.34008CCT245232
CAS:<p>CCT245232 is a potent HSF1 inhibitor, possibly used for researching cancer.</p>Fórmula:C27H23N3O4Forma y color:SolidPeso molecular:453.49PU-H71
CAS:<p>PU-H71 is an effective selective HSP90 inhibitor with an IC50 of 51 nM.</p>Fórmula:C18H21IN6O2SPureza:98.31% - 99.937%Forma y color:SolidPeso molecular:512.37Debio 0932
CAS:<p>Debio 0932 (CUDC-305) is a Hsp9 inhibitor, apoptosis, and has the advantage of being orally available and cross the BBB for cancers NSCLC and neuroblastoma.</p>Fórmula:C22H30N6O2SPureza:98.98%Forma y color:SolidPeso molecular:442.58Palmitic acid-1-13C
CAS:<p>Palmitic acid-13C, a 16-C saturated fatty acid internal standard for GC/LC-MS, is prevalent in plasma lipids and influences protein acylation and COX-2 levels.</p>Fórmula:C16H32O2Forma y color:SolidPeso molecular:257.422L-Alanyl-L-glutamine
CAS:<p>L-Alanyl-L-glutamine (Ala-Gln), a dipeptide composed of alanine and Gln, is an alternative supplement to L-glutamine in the production of biopharmaceuticals.</p>Fórmula:C8H15N3O4Pureza:99.71% - 99.97%Forma y color:SolidPeso molecular:217.22YUM70
CAS:<p>YUM70 inhibits GRP78 (IC50: 1.5μM), inducing ER stress and apoptosis in pancreatic cancer.</p>Fórmula:C21H19ClN2O4Pureza:97.25%Forma y color:SolidPeso molecular:398.84MitoBloCK-10
CAS:<p>MitoBloCK-10 inhibits Tim44-Hsp70 binding; first to reduce PAM complex activity.</p>Fórmula:C12H8FN3O3SPureza:99.51%Forma y color:SolidPeso molecular:293.27HSF1A
CAS:<p>HSF1A is a cell-permeable activator of HSF1 that protects mammalian cells against stress-induced apoptosis.</p>Fórmula:C21H19N3O2S2Pureza:98.89%Forma y color:SolidPeso molecular:409.52Dihydroberberine
CAS:<p>Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities.</p>Fórmula:C20H19NO4Pureza:93.77%Forma y color:SolidPeso molecular:337.37PF04929113
CAS:<p>PF04929113 (SNX-5422), a synthetic small molecule Hsp90 inhibitor, offers potent efficacy orally for various cancers.</p>Fórmula:C25H30F3N5O4Pureza:99.04%Forma y color:SolidPeso molecular:521.53PF-04929113 Mesylate
CAS:<p>PF-04929113 Mesylate (SNX-5422 Mesylate), a prodrug of SNX-2112, is an orally available Hsp90 inhibitor (Kd: 41 nM) and also induces Her-2 degradation (IC50: 37</p>Fórmula:C26H34F3N5O7SPureza:99% - 99.46%Forma y color:SolidPeso molecular:617.63Luminespib
CAS:<p>Luminespib (VER-52296) is an HSP90 inhibitor that inhibits HSP90α and HSP90β. Luminespib has antitumor activity. Cost-effective and quality-assured.</p>Fórmula:C26H31N3O5Pureza:98% - 99.25%Forma y color:SolidPeso molecular:465.54MK2-IN-1 hydrochloride
CAS:<p>MK2-IN-1 hydrochloride (MK 25) selectively inhibits MK2 with IC50 of 0.11 μM, non-ATP competitive.</p>Fórmula:C27H26Cl2N4O2Pureza:97.32%Forma y color:SolidPeso molecular:509.43Onalespib
CAS:<p>Onalespib (AT13387) is an oral Hsp90 inhibitor with anticancer potential, disrupting tumor cell growth and survival.</p>Fórmula:C24H31N3O3Pureza:98.05% - 99.66%Forma y color:SolidPeso molecular:409.52XL888
CAS:<p>XL888 is an orally bioavailable Hsp90 inhibitor, blocking cell proliferation and inducing tumor regression with an IC50 of 24 nM.</p>Fórmula:C29H37N5O3Pureza:99.18%Forma y color:SolidPeso molecular:503.64Azadiradione
CAS:<p>Azadiradione (AZD) (AZD) from the methanolic extract of seeds of Azadirachta indica</p>Fórmula:C28H34O5Pureza:99.52%Forma y color:SolidPeso molecular:450.57
