HSP
Los inhibidores de proteínas de choque térmico (HSP) se dirigen a las HSP, una familia de chaperonas moleculares que asisten en el plegamiento de proteínas, la estabilidad y la protección contra daños inducidos por el estrés. Las HSP suelen estar sobreexpresadas en células cancerosas, ayudándolas a sobrevivir en condiciones estresantes como la hipoxia y la quimioterapia. Inhibir las HSP puede interrumpir estos mecanismos de protección, lo que conduce a la muerte celular. Por lo tanto, los inhibidores de HSP son valiosos en la terapia contra el cáncer y en la investigación de respuestas al estrés. En CymitQuimica, ofrecemos una amplia gama de inhibidores de HSP de alta calidad para apoyar su investigación en homeostasis de proteínas, respuestas al estrés y oncología.
Se han encontrado 169 productos de "HSP"
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KW-2478
CAS:<p>KW-2478 is a non-ansamycin HSP90 inhibitor with IC50 of 3.8 nM.</p>Fórmula:C30H42N2O9Pureza:98.68% - 99.52%Forma y color:SolidPeso molecular:574.66Alvespimycin
CAS:<p>Alvespimycin (17-DMAG) is a potent Hsp90 inhibitor with potential anticancer activity, which acts by binding to Hsp90.</p>Fórmula:C32H48N4O8Pureza:99.88%Forma y color:SolidPeso molecular:616.75Calenduloside E
CAS:<p>Calenduloside E (Silphioside F) exhibits hypoglycemic activities by suppressing the transfer of glucose from the stomach to the small intestine and by</p>Fórmula:C36H56O9Pureza:96.16% - 98.99%Forma y color:SolidPeso molecular:632.8217-AEP-GA
CAS:<p>17-AEP-GA is an HSP90 antagonist and a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion.</p>Fórmula:C34H50N4O8Pureza:97.77% - 99.56%Forma y color:SolidPeso molecular:642.78Retaspimycin Hydrochloride
CAS:<p>Retaspimycin Hydrochloride is a potent and water-soluble Hsp90 inhibitor(Hsp90 and Grp9 with EC50s of 119 nM).</p>Fórmula:C31H46ClN3O8Pureza:98%Forma y color:SolidPeso molecular:624.17Bimoclomol
CAS:<p>Bimoclomol is a heat shock protein co-inducer used for the research of cardiovascular diseases.</p>Fórmula:C14H20ClN3O2Forma y color:SolidPeso molecular:297.78CH5138303
CAS:<p>CH5138303 is an orally available Hsp90 inhibitor with Kd of 0.48 nM.</p>Fórmula:C19H18ClN5O2SPureza:98%Forma y color:SolidPeso molecular:415.9AMP-PCP
CAS:<p>AMP-PCP is an ATP analog and can bind to the Hsp90 N-terminal domain (Kd: 3.8 μM). AMP-PCP binding favors the formation of the active homodimer of Hsp90.</p>Fórmula:C11H18N5O12P3Pureza:98%Forma y color:SolidPeso molecular:505.21JG-48
CAS:<p>JG-48 is an inhibitor of Hsp70. JG-48 suppresses phosphorylated and total Tau in cells, endogenous Tau in neuroblastoma cells.</p>Fórmula:C20H16F3N3OS2Forma y color:SolidPeso molecular:435.49Hsp90-IN-15
CAS:<p>Hsp90-IN-15: Hsp90 blocker with anticancer properties; halts S phase, triggers apoptosis, cuts Hsp90 in Hela cells.</p>Fórmula:C23H27F3N4Forma y color:SolidPeso molecular:416.48CCT251236
CAS:<p>CCT251236 is an orally available Pirin ligand obtained from a heat shock transcription factor 1 (hsf1) phenotypic screen.</p>Fórmula:C32H32N4O5Pureza:98.82% - 99.89%Forma y color:SolidPeso molecular:552.62HSP90-IN-12
CAS:<p>VAC, a potent anti-cancer vibsanin A analog, inhibits cell proliferation and affects HSP90 protein levels.</p>Fórmula:C25H36O4Forma y color:SolidPeso molecular:400.55YM-01 Tosylate
CAS:<p>YM-01 Tosylate, a potent antitumor agent, selectively targets cancer cells and overcoming tamoxifen resistance.</p>Fórmula:C27H27N3O4S3Forma y color:SolidPeso molecular:553.72Displurigen
CAS:<p>Displurigen is an inhibitor of ATPase activity of HSP70.</p>Fórmula:C15H10O4SPureza:98%Forma y color:SolidPeso molecular:286.3Malonganenone A
CAS:<p>Malonganenone A is a selective plasmodial Hsp70s modulator. It also has antimalarial activity.</p>Fórmula:C26H38N4O2Forma y color:SolidPeso molecular:438.616BrCaQ
CAS:<p>6BrCaQ inhibits TRAP1, has antiproliferative effects, and is used in 6BrCaQ-TPP synthesis.</p>Fórmula:C18H15BrN2O3Forma y color:SolidPeso molecular:387.23HSP90-IN-22
CAS:<p>HSP90-IN-22 (Compound 35) is an Hsp90 inhibitor exhibiting antiproliferative activity, with IC50 values of 3.65 μM in MCF7 breast cancer cells and 2.71 μM in</p>Fórmula:C25H30N4O3Pureza:98%Forma y color:SolidPeso molecular:434.53PU3
CAS:<p>PU3 is an inhibitor of Hsp90.</p>Fórmula:C19H25N5O3Pureza:98%Forma y color:SolidPeso molecular:371.43SEW84
CAS:<p>SEW84, an Aha1-stimulated Hsp90 inhibitor, has an IC50 of 0.3 μM, aiding protein deposition disease research.</p>Fórmula:C19H14F4N4OSForma y color:SolidPeso molecular:422.4HSP90-IN-14
CAS:<p>HSP90-IN-14 inhibits Hsp90 (Kd=0.26 μM) and fights influenza A/H3N2, A/H1N1, B with EC50 of 2.6, 3.9, 17 μM in MDCK cells.</p>Fórmula:C14H8Cl2N4O4SForma y color:SolidPeso molecular:399.21
