HSP
Los inhibidores de proteínas de choque térmico (HSP) se dirigen a las HSP, una familia de chaperonas moleculares que asisten en el plegamiento de proteínas, la estabilidad y la protección contra daños inducidos por el estrés. Las HSP suelen estar sobreexpresadas en células cancerosas, ayudándolas a sobrevivir en condiciones estresantes como la hipoxia y la quimioterapia. Inhibir las HSP puede interrumpir estos mecanismos de protección, lo que conduce a la muerte celular. Por lo tanto, los inhibidores de HSP son valiosos en la terapia contra el cáncer y en la investigación de respuestas al estrés. En CymitQuimica, ofrecemos una amplia gama de inhibidores de HSP de alta calidad para apoyar su investigación en homeostasis de proteínas, respuestas al estrés y oncología.
Se han encontrado 185 productos para "HSP".
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Bimoclomol
CAS:Bimoclomol is a heat shock protein co-inducer used for the research of cardiovascular diseases.Fórmula:C14H20ClN3O2Forma y color:SolidPeso molecular:297.78Retaspimycin
CAS:Retaspimycin is a potent and water-soluble Hsp90 inhibitor(EC50s of 119 nM for both Hsp90 and Grp9).Fórmula:C31H45N3O8Pureza:98%Forma y color:SolidPeso molecular:587.7MPC-3100
CAS:MPC-3100 is an orally bioavailable, synthetic, second-generation small-molecule inhibitor of Hsp90 with significant antitumor activity [1].Fórmula:C22H25BrN6O4SForma y color:SolidPeso molecular:549.44Retaspimycin Hydrochloride
CAS:Retaspimycin Hydrochloride is a potent and water-soluble Hsp90 inhibitor(Hsp90 and Grp9 with EC50s of 119 nM).Fórmula:C31H46ClN3O8Pureza:98%Forma y color:SolidPeso molecular:624.17BIIB028
CAS:BIIB028: Hsp90 inhibitor, may degrade oncogenic proteins, potentially hindering tumor growth.Fórmula:C19H21ClN5O5PForma y color:SolidPeso molecular:465.83Iroxanadine
CAS:Iroxanadine (BRX-005) is a Novel small molecule MAPK p38 inhibitor that induces phosphorylation of p38 SAPK and induces concentration-dependent relaxation inFórmula:C14H20N4OPureza:98.04% - 99.04%Forma y color:SolidPeso molecular:260.33SNX0723
CAS:SNX0723 is a potent Hsp90 Inhibitor with anti-Plasmodium activity.Fórmula:C22H26FN3O3Pureza:99.85%Forma y color:White SolidPeso molecular:399.46Ref: TM-T28824
500mgA consultar1mg85,00€5mg178,00€1mL*10mM (DMSO)195,00€10mg299,00€25mg485,00€50mg665,00€100mg892,00€Arimoclomol
CAS:Arimoclomol (BRX-220 free base) is a co-inducer of heat shock proteins (HSP) and can be used in studies about the treatment of amyotrophic lateral sclerosis (Fórmula:C14H20ClN3O3Pureza:99.15%Forma y color:SolidPeso molecular:313.78GRP78-IN-2
CAS:GRP78-IN-2 inhibits surface GRP78, showing anti-angiogenic and anti-cancer properties, sparing normal cells.Fórmula:C29H29NO6Forma y color:SolidPeso molecular:487.54KU-177
CAS:KU-177 is an Aha1 inhibitor that disrupts the interaction between Hsp90 and Aha1, eliminating cell proliferation and PI resistance induced by elevated AHSA1.Fórmula:C27H23NO8Pureza:96.92% - 98.54%Forma y color:SolidPeso molecular:489.47YM-08
CAS:YM-08 (Compound 7a), a brain-penetrant SIRT2 inhibitor, exhibits an IC50 of 19.9 μM. Additionally, it acts as an inhibitor of Hsp70 [1].Fórmula:C19H17N3OS2Pureza:98%Forma y color:SolidPeso molecular:367.49BX-2819
CAS:BX-2819 is an Hsp90 inhibitor that exhibits potent antiproliferative activity with an IC50 of 41 nM .Fórmula:C21H24N4O4SPureza:98%Forma y color:SolidPeso molecular:428.51HSP90-IN-29
CAS:HSP90-IN-29 (Compound 13), a benzoxazole derivative, serves as a potent and selective HSP-90 inhibitor, exhibiting a low IC50 value of 30 nM. This compound demonstrates significant antitumor activity [1].Fórmula:C19H20ClN3O4Forma y color:SolidPeso molecular:389.83HA15-Biotin
CAS:HA15-Biotin, a synthetic HA15-biotin conjugate, shows similar activity and may aid in proteomics.Fórmula:C37H45N7O5S3Forma y color:SolidPeso molecular:763.99HSP90-IN-27
CAS:HSP90-IN-27 (compound 19) is an effective HSP90 inhibitor for cancer research.Fórmula:C18H21N3O2SPureza:99.94%Forma y color:White SolidPeso molecular:343.44HSP70/SIRT2-IN-2
CAS:HSP70/SIRT2-IN-2 (Compounds 1a), a dual inhibitor of SIRT2 and HSP70, exhibits an IC50 of 45.1±5.0 μM against SIRT2 and demonstrates antitumor activity [1].Fórmula:C17H13N3S3Pureza:98%Forma y color:SolidPeso molecular:355.5HSP90-IN-19
CAS:HSP90-IN-19: potent Hsp90 inhibitor, IC50 = 0.27 μM, used in research on viral diseases, neurodegeneration, inflammation.Fórmula:C29H38O7Pureza:98%Forma y color:SolidPeso molecular:498.61Iroxanadine sulfate
CAS:Iroxanadine sulfate is a MAPK p38 inhibitor potentially for the treatment of atherosclerosis.Fórmula:C14H22N4O5SForma y color:SolidPeso molecular:358.41MAO A/HSP90-IN-1
CAS:MAO A/HSP90-IN-1 (4-b) is a dual inhibitor of MAO A and HSP90, exhibiting IC50 values of 1.77 μM in glioblastoma (GBM) GL26 cells and 0.019 μM against HSP90α.Fórmula:C24H29ClN2O4Pureza:98%Forma y color:SolidPeso molecular:444.95MAO A/HSP90-IN-2
CAS:MAO A/HSP90-IN-2 (compound 4-C), a dual inhibitor of HSP90 and MAO A, exhibits IC50 values of 0.016 μM for MAO A and 4.58 μM for HSP90.Fórmula:C25H31ClN2O4Pureza:98%Forma y color:SolidPeso molecular:458.98
