Cromatina / Epigenética
Los inhibidores de cromatina/epigenética son compuestos que modulan la estructura y función de la cromatina o interfieren con modificaciones epigenéticas, como la metilación del ADN y la modificación de histonas. Estos inhibidores son herramientas esenciales para estudiar la regulación de la expresión génica y el papel de la epigenética en enfermedades como el cáncer, los trastornos neurológicos y las anomalías del desarrollo. Al dirigirse a los procesos epigenéticos, estos inhibidores pueden alterar los patrones de expresión génica y ofrecer nuevas vías terapéuticas. En CymitQuimica, ofrecemos una amplia selección de inhibidores de cromatina/epigenética de alta calidad para apoyar su investigación en biología molecular, genética y epigenética.
Subcategorías de "Cromatina / Epigenética"
Se han encontrado 2235 productos de "Cromatina / Epigenética"
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NSC 694623
CAS:<p>NSC 694623: Potent HAT inhibitor, IC50=15.9 μM against PCAF, anti-cancer properties.</p>Fórmula:C16H16N2OSPureza:99.9%Forma y color:SolidPeso molecular:284.38Flosequinan
CAS:<p>Flosequinan is an arteriovenous vasodilator, which can effectively treat acute heart failure.</p>Fórmula:C11H10FNO2SPureza:99.95%Forma y color:SolidPeso molecular:239.27Chiauranib
CAS:<p>Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.</p>Fórmula:C27H21N3O3Pureza:99.22%Forma y color:SolidPeso molecular:435.47SK-575
CAS:<p>SK-575 is a potent PARP1-degrading agent effective against BRCA1/2 mutant cancers, even at low doses, and enhances tumor inhibition in mice.</p>Fórmula:C47H53FN8O8Pureza:99.39%Forma y color:SolidPeso molecular:876.97β-NF-JQ1
CAS:<p>β-NF-JQ1 is a PROTAC that recruits aryl hydrocarbon receptor E3 (AhR E3) ligase to target proteins.</p>Fórmula:C45H42ClN5O6SPureza:97.58% - 99.15%Forma y color:SolidPeso molecular:816.36BRD4 Inhibitor-20
CAS:<p>BRD4 Inhibitor-20 is a potent bromodomain protein 4 (BRD4) inhibitor with oral activity.</p>Fórmula:C18H18N2O4SPureza:99.84%Forma y color:SolidPeso molecular:358.41GSK-690
CAS:<p>GSK-690 is a potent, reversible and selective inhibitors of Lysine Specific Demethylase 1.</p>Fórmula:C24H23N3OPureza:98.65%Forma y color:SolidPeso molecular:369.46CD532
CAS:<p>CD532: Potent Aurora A inhibitor, IC50=45 nM, blocks kinase activity, degrades MYCN, interacts with AURKA, studies cancer.</p>Fórmula:C26H25F3N8OPureza:99.49%Forma y color:SolidPeso molecular:522.52JAK-STAT-IN-1
CAS:<p>JAK-STAT-IN-1 is a specific JAK-STAT inhibitor indicated for the study of autoimmune diseases.</p>Fórmula:C21H21N5O2Pureza:99.59%Forma y color:SolidPeso molecular:375.42ML192
CAS:<p>ML192 (CID1434953) is a selective GPR55 ligand antagonist.</p>Fórmula:C20H22N4O2SPureza:99.17%Forma y color:SolidPeso molecular:382.48SRX3177
CAS:<p>SRX3177 is a novel and potent inhibitor of BRD4, PI3K and CDK.SRX3177 has potential anticancer activity.</p>Fórmula:C31H32N6O4SPureza:99.16%Forma y color:SolidPeso molecular:584.69KRH102140
CAS:<p>KRH102140 is a PHD2 activator that reduces angiogenesis by inhibiting HIF-1alpha, used in cardiovascular disease research.</p>Fórmula:C25H24FNOPureza:98.31% - 99.61%Forma y color:SolidPeso molecular:373.46Bisaramil hydrochloride
CAS:<p>Bisaramil hydrochloride (Bisaramil) is an antiarrhythmic compound that inhibits free radical production.</p>Fórmula:C17H24Cl2N2O2Pureza:98.64% - 99.48%Forma y color:SolidPeso molecular:359.29AGI-24512
CAS:<p>AGI-24512 is a inhibitor of methionine adenosyltransferase 2A (MATA2 ).It is useful for treatment of cancer and blocks growth of MTAP-deleted cancer cells in</p>Fórmula:C24H24N4O2Pureza:98.55%Forma y color:SolidPeso molecular:400.47MAT2A-IN-9
CAS:<p>MAT2A-IN-9, a 2-oxoquinazoline, inhibits MAT2A with antitumor effects on lymphomas and solid cancers.</p>Fórmula:C14H8ClF3N4OPureza:99.17%Forma y color:SolidPeso molecular:340.69R 59-022 hydrochloride
CAS:<p>R 59-022 hydrochloride is a 5-HT antagonist, PKC activator, DGK inhibitor (IC50: 2.8 µM), and modulates lipid production in platelets and neutrophils.</p>Fórmula:C27H27ClFN3OSPureza:97.7%Forma y color:SolidPeso molecular:496.04OXF BD 02
CAS:<p>OXF BD 02 is a potent and selective BRD4(1) inhibitor (IC50: 382 nM) with anticancer and anti-inflammatory activity.</p>Fórmula:C18H17NO3Pureza:98.25%Forma y color:SolidPeso molecular:295.33MS0124
CAS:<p>MS0124 is a potent and selective G9A-like protein (GLP) inhibitor with IC50 values of 13±4 nM and 440±63 nM, respectively.</p>Fórmula:C20H29N5O3Pureza:98.97%Forma y color:SolidPeso molecular:387.48CARM1-IN-1
CAS:<p>CARM1-IN-1 (CARM1-IN-7G) is a selective inhibitor of CARM1 with IC50 of 8.6 μM. CARM1-IN-1 shows weak activity against PRMT1 and SET7 with IC50 > 600 μM.</p>Fórmula:C26H21Br2NO3Pureza:98.24%Forma y color:SolidPeso molecular:555.26LSD1-IN-20
CAS:<p>LSD1-IN-20: Dual LSD1/G9a inhibitor, Ki 0.44/0.68 μM; hampers THP-1, MDA-MB-231 cell growth with IC50 0.51/1.60 μM at 72h.</p>Fórmula:C27H38N6O2Pureza:98.44% - 99.57%Forma y color:SolidPeso molecular:478.63EB-47
CAS:<p>EB-47 imitates NAD+, spans nicotinamide to adenosine sites, inhibits PARP-1 (IC50: 45 nM) and is less effective on ARTD5 (IC50: 410 nM).</p>Fórmula:C24H27N9O6Pureza:99.81%Forma y color:SolidPeso molecular:537.53Corin
CAS:<p>Corin is an irreversible inhibitor of HDAC1(IC50 = 147 nM) and LSD1(Ki = 110 nM).</p>Fórmula:C26H28N4O2Pureza:99.6%Forma y color:SolidPeso molecular:428.53JAK1-IN-8
CAS:<p>JAK1-IN-8, a specific inhibitor of Janus kinase 1 (JAK1, IC50<500 nM).</p>Fórmula:C22H23FN4O3SPureza:98.4%Forma y color:SolidPeso molecular:442.51OXFBD04
CAS:<p>OXFBD04: Potent BRD4 inhibitor, IC50=166nM, acts on BET bromodomains; moderate CREBBP affinity; anti-cancer properties.</p>Fórmula:C17H16N2O3Pureza:99.56%Forma y color:SolidPeso molecular:296.32ZEN-3862
CAS:<p>ZEN-3862, a BET inhibitor, blocks BRD4(BD1) at 0.16 μM & BRD4(BD2) at 0.13 μM; usable in PROTACs for BRD4 degradation.</p>Fórmula:C19H17FN2O3Pureza:97.1%Forma y color:SolidPeso molecular:340.35OUL232
CAS:<p>OUL232 is a potent single ARTs PARP7, PARP10, PARP11, PARP12, PARP14 and PARP15 inhibitor for cancer and tumour research.</p>Fórmula:C10H10N4O2SPureza:99.04%Forma y color:SolidPeso molecular:250.28Izencitinib
CAS:<p>Izencitinib (JNJ-8398) is a JAK inhibitor with potential anti-inflammatory activity for the study of ulcerative colitis and Crohn;s disease.</p>Fórmula:C22H26N8Pureza:99.82%Forma y color:SolidPeso molecular:402.50PARP10-IN-2
CAS:<p>PARP10-IN-2 is a potent inhibitor of PARP10, a mono-ADP-ribosyltransferase, with an IC50 value of 3.64 μM for human PARP10.PARP10-IN-2 also inhibited PARP2 and</p>Fórmula:C14H10N2O2Pureza:99.27%Forma y color:SolidPeso molecular:238.24ZEN-3411
CAS:<p>ZEN-3411 is an BET inhibitor that inhibits BRD4(BD1), BRD4(BD2), and BRD4(BD1BD2) and suppresses the growth of tumor cells overproducing BET proteins.</p>Fórmula:C21H20N4O2Pureza:97.51% - 98.84%Forma y color:SolidPeso molecular:360.41AGI-43192
CAS:<p>AGI-43192: potent MAT2A inhibitor, crosses blood-brain barrier, may help study SAM in CNS and treat cancer.</p>Fórmula:C23H16ClF3N6OPureza:99.89%Forma y color:SolidPeso molecular:484.86HDAC6 degrader 9c
CAS:<p>HDAC6 degrader 9c is a small molecule histone deacetylase 6 (HDAC6) degrader that can be used to study cancer or other diseases.</p>Fórmula:C37H45N9O10Pureza:>99.99%Forma y color:SolidPeso molecular:775.81ZEN-2759
CAS:<p>ZEN-2759 is a potent BET small molecule inhibitor of BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2).</p>Fórmula:C17H16N2O2Pureza:99.36%Forma y color:SolidPeso molecular:280.32Bobcat339 hydrochloride
CAS:<p>Bobcat339 hydrochloride is a 10 11 translocation (TET) dioxygenase inhibitor that inhibits both TET1 and TET2.</p>Fórmula:C16H13Cl2N3OPureza:99.22%Forma y color:SolidPeso molecular:334.2GSK761
<p>GSK761 inhibits SP140 (IC50: 77.79 nM), hinders monocyte-to-macrophage differentiation, and prompts CD206+ regulatory macrophages.</p>Fórmula:C40H46N4O4Forma y color:SolidPeso molecular:646.82CBB1007 hydrochloride
CAS:<p>CBB1007 Hcl inhibits LSD1 selectively (IC50=5.27μM), blocks H3K4 demethylation, activates genes; less effect on other cells/tissues.</p>Fórmula:C27H39Cl5N8O4Forma y color:SoildPeso molecular:716.91KH-3
CAS:<p>KH-3: HuR inhibitor, IC50 0.35 μM, halts cell growth, blocks HuR-FOXQ1 mRNA, curbs breast cancer invasion, slows lung colony growth.</p>Fórmula:C21H22N2O4S2Forma y color:SolidPeso molecular:430.54PARP7-IN-16
CAS:<p>PARP7-IN-16 (compound 36) is a potent, selective, and orally active PARP-1/2/7 inhibitor, exhibiting IC50 values of 0.94, 0.87, and 0.21 nM , respectively.</p>Fórmula:C25H26FN4NaO4Pureza:98%Forma y color:SolidPeso molecular:488.49PHD-IN-1
CAS:<p>PHD-IN-1 (compound 80) serves as a potent PHD2 inhibitor, exhibiting an IC50 value of ≤5 nM.</p>Fórmula:C24H23N7O2Pureza:98%Forma y color:SolidPeso molecular:441.49CBP/p300-IN-17
CAS:<p>CBP/p300-IN-17 (compound 7) is a potent inhibitor of EP300/CBP HAT, acting on HAT EP300 (IC50: 0.18 μM) and LK2 H3K27 (IC50: 0.69 μM).</p>Fórmula:C25H28N4O3Forma y color:SolidPeso molecular:432.51JAK2-IN-4
CAS:<p>JAK2-IN-4 is a selective JAK2/JAK3 inhibitor, with IC50 values of 0.7 nM and 23.2 nM for JAK2 and JAK3, respectively.</p>Fórmula:C23H27N5O4SPureza:98%Forma y color:SolidPeso molecular:469.56PARP-2-IN-1
CAS:<p>PARP-2-IN-1 is a potent and selective inhibitor of PARP-2(IC50 of 11.5 nM).</p>Fórmula:C21H19F4N5O3Pureza:98%Forma y color:SolidPeso molecular:465.4FHT-1204
CAS:<p>FHT-1204 is a potent inhibitor of SMARCA4/SMARCA2 ATPase (BRG1 and BRM) (IC50 ≤ 10 nM).</p>Fórmula:C24H23N5O5S2Forma y color:SolidPeso molecular:525.6HDAC-IN-38
CAS:<p>HDAC-IN-38: Potent HDAC1-3,5,6,8 inhibitor, boosts H3K14/H4K5 acetylation, elevates CBF, lessens cognitive decline & hippocampal atrophy.</p>Fórmula:C27H28ClN3O2Forma y color:SolidPeso molecular:461.98PI3K/HDAC-IN-2
CAS:<p>PI3K/HDAC-IN-2: dual inhibitor with IC50s - PI3Kα: 226nM, β: 279nM, γ: 467nM, δ: 29nM; HDAC1: 1.3nM. Selective to PI3Kδ/class I/IIb HDAC, anticancer.</p>Fórmula:C23H23N7O4Forma y color:SolidPeso molecular:461.47FHT-2344
CAS:<p>FHT-2344, a SMARCA4/SMARCA2 ATPase inhibitor, exhibits anticancer activity with half-maximal inhibitory concentrations (IC 50 ) of 0.026 μM for SMARCA4 and 0.013 μM for SMARCA2, respectively [1].</p>Fórmula:C23H24N6O5S2Forma y color:SolidPeso molecular:528.6HDAC6-IN-34
CAS:<p>HDAC6-IN-34 (compound 21), an orally active, selective HDAC6 inhibitor, exhibits an IC50 of 18 nM. It enhances tubulin acetylation levels without impacting histone acetylation in cutaneous T-cell lymphoma cells and suppresses TNF-α secretion in LPS-stimulated macrophage cells. Furthermore, HDAC6-IN-34 demonstrates outstanding anti-arthritic efficacy in rats [1].</p>Fórmula:C18H18F3N3O3Forma y color:SolidPeso molecular:381.35DNMT-IN-3
CAS:<p>DNMT-IN-3 is a DNA Methyltransferase (DNMT) inhibitor with an IC50 of 60 nM against Plasmodium falciparum (Plasmodium), demonstrating antimalarial activity and suitability for malaria-related research [1].</p>Fórmula:C37H39N7OForma y color:SolidPeso molecular:597.75F-Amidine TFA
CAS:<p>F-amidine is a selective inhibitor of protein arginine deiminases (PADs), specifically targeting PAD1 and PAD4 with in vitro IC50 values of 29.5, 350, and 21.6 µM for PAD1, PAD3, and PAD4, respectively. It irreversibly inactivates all four PAD subtypes by covalently modifying an active site cysteine crucial for enzymatic activity, with kinact/KI values of 2,800, 380, 170, and 3,000 M^-1min^-1. Additionally, F-amidine demonstrates cytotoxicity against HL-60, MCF-7, and HT-29 cancer cell lines, with IC50s of 0.5, 0.5, and 1 μM, respectively.</p>Fórmula:C14H19FN4O2CF3COOHForma y color:SolidPeso molecular:408.4Itacnosertib (hydrocholide)
CAS:<p>Itacnosertib hydrochloride acts as an inhibitor targeting JAK2, ACVR1 (ALK2), and ALK5 [1].</p>Fórmula:C26H29ClN8OForma y color:SolidPeso molecular:505.01CW 008
CAS:<p>CW 008 is an agonist of the cAMP/PKA/CREB pathway, promoting osteogenic differentiation of bone marrow-derived mesenchymal stem cells (MSCs).a PKA activator.</p>Fórmula:C21H14F2N6O2Pureza:97.39%Forma y color:SolidPeso molecular:420.37JBI-589
CAS:<p>JBI-589 is an isoform-selective, non-covalent inhibitor of PAD4 that diminishes CXCR2 expression and impedes neutrophil chemotaxis.</p>Fórmula:C29H28FN5OForma y color:SolidPeso molecular:481.56JAK-IN-26
CAS:<p>JAK-IN-26 (compound 2) is an orally active inhibitor of the Janus kinase (JAK) enzyme with favorable pharmacokinetic properties, exhibiting potency in</p>Fórmula:C22H24N6O3Pureza:98%Forma y color:SolidPeso molecular:420.46JAK-IN-1
CAS:<p>JAK-IN-1 shows improved selectivity for JAK3 over JAK1. JAK-IN-1 is a JAK1/2/3 inhibitor with IC50s of 0.26, 0.8 and 3.2 nM, respectively.</p>Fórmula:C20H24N6O2Pureza:98%Forma y color:SolidPeso molecular:380.44CAY10398
CAS:<p>CAY10398 is a compound that serves as an isoform-selective inhibitor of histone deacetylase (HDAC1).</p>Fórmula:C15H23N3O3Forma y color:SolidPeso molecular:293.367MS023 trihydrochloride
CAS:<p>MS023 trihydrochloride (MS023 3HCl) is a PRMT inhibitor with potential anticancer activity against PRMT1, PRMT3, PRMT4, PRMT6, and PRMT8 for cancer research.</p>Fórmula:C17H28Cl3N3OPureza:99.81%Forma y color:SolidPeso molecular:396.78dBRD4-BD1
CAS:<p>dBRD4-BD1 selectively inhibits and degrades BRD4 (DC50=280nM), upregulates BRD2/3, and aids in creating BRD4-specific probes.</p>Fórmula:C50H53F3N8O9Forma y color:SolidPeso molecular:967Tubulin/JAK2-IN-1
CAS:<p>Tubulin/JAK2-IN-1 (compound 7g) serves as a potent dual inhibitor targeting both Janus kinase 2 (JAK2) and microtubules, demonstrating significant</p>Fórmula:C22H20N6O3Forma y color:SolidPeso molecular:416.43KDM5-IN-1
CAS:<p>KDM5-IN-1 is an effective and selective inhibitor of KDM5 with an IC50 of 15.1 nM.</p>Fórmula:C17H20N6OPureza:99.50%Forma y color:SolidPeso molecular:324.38HIF-2α-IN-13
CAS:<p>HIF-2α-IN-13 (18) acts as a HIF-2α inhibitor and exhibits an IC 50 value of 2.7 μM.</p>Fórmula:C15H14ClF4NO2Forma y color:SolidPeso molecular:351.72KF21213
CAS:<p>KF21213 shows a high affinity for the adenosine A2A receptors (Ki=3.0 nM). KF21213 is a highly selective ligand for mapping CNS adenosine A2A receptors.</p>Fórmula:C19H22N4O3Pureza:98%Forma y color:SolidPeso molecular:354.4Lepzacitinib
CAS:<p>Lepzacitinib is a selective, inflammatory, small molecule JAK1/3(Janus kinase) inhibitor primarily used for the treatment of atopic dermatitis.</p>Fórmula:C18H21N5O3Pureza:99.85%Forma y color:SolidPeso molecular:355.39KAT modulator-1
CAS:<p>KAT modulator-1 (Compound 3), an epigenetics research tool, selectively interacts with the full-length p300 protein but not its catalytic domain [1].</p>Fórmula:C20H36O2Pureza:98%Forma y color:SolidPeso molecular:308.5BY27
CAS:<p>BY27 is a BET BD2 inhibitor with anticancer activity that inhibits BRD2, BRD3 and BRD4 and suppresses tumor growth.</p>Fórmula:C22H21ClN6Pureza:99.4% - 99.68%Forma y color:SolidPeso molecular:404.89Lin281632
CAS:<p>Lin281632 is an inhibitor of RNA binding protein Lin28 and bromodomain. Lin281632 promotes mESC differentiation.</p>Fórmula:C15H15N5OPureza:99.84%Forma y color:SolidPeso molecular:281.31BRCA1-IN-2
CAS:<p>BRCA1-IN-2 is a cell membrane-crossing BRCA1 protein-protein interaction (PPI) inhibitor with antitumor activity that acts by disrupting the interaction of BRCA1 (BRCT)2 with proteins.</p>Fórmula:C26H33N4O7PPureza:98.04%Forma y color:SolidPeso molecular:544.54ZL0420
CAS:<p>ZL0420: Potent, selective BRD4 inhibitor, IC50 27 nM BD1 & 32 nM BD2.</p>Fórmula:C16H16N4O2Pureza:99.38%Forma y color:SolidPeso molecular:296.32ZINC08792355
CAS:<p>ZINC08792355 is a novel inhibitor of SIRT1.</p>Fórmula:C31H24N4O3Forma y color:SolidPeso molecular:500.55RTS-V5
CAS:<p>RTS-V5 is a dual inhibitor of HDAC/proteasome (IC50s: 6.9, 18, 15, 0.27, 0.53 μM for HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, respectively).</p>Fórmula:C27H35N5O6Pureza:98%Forma y color:SolidPeso molecular:525.6CBP/p300-IN-5
CAS:<p>P300/CBP-IN-5 is a potent inhibitor of p300/CBP histone acetyltransferase (IC50 of 18.8 nM).</p>Fórmula:C29H27F5N6O4Pureza:98%Forma y color:SolidPeso molecular:618.55Luteolin 7-sulfate
CAS:<p>Luteolin 7-sulfate from Phyllospadix iwatensis inhibits melanin production by disrupting CREB/MITF signaling.</p>Fórmula:C15H10O9SPureza:98%Forma y color:SolidPeso molecular:366.3CLB-016
CAS:<p>CLB-016 is an inhibitor of hypoxia-inducible factor (HIF)-1.</p>Fórmula:C17H20N6O3Pureza:98%Forma y color:SolidPeso molecular:356.38A1B11
CAS:<p>A1B11 is a selective SIRT2 inhibitor.</p>Fórmula:C22H25N5OForma y color:SolidPeso molecular:375.47PARPYnD
CAS:<p>PARPYnD: Photoaffinity PARP probe; inhibits PARP2, PARP1, PARP6 (IC50: 6, 38, 230 nM); tags PARP1/2 with N3 fluorescent probe.</p>Fórmula:C34H31N9O3Forma y color:SolidPeso molecular:613.67I-BET762 carboxylic acid
CAS:<p>I-BET762 carboxylic acid is an inhibitor of BRD4(pIC50 of 5.1).</p>Fórmula:C20H17ClN4O3Pureza:98%Forma y color:SolidPeso molecular:396.83L-Moses
CAS:<p>L-45 is the first potent and cell-active bromodomain (Brd) inhibitor of p300/CBP-associated factor (PCAF) (Kd: 126±15 nM).</p>Fórmula:C21H24N6Pureza:98%Forma y color:SolidPeso molecular:360.46ZINC08792229
CAS:<p>ZINC08792229 is a novel inhibitor of SIRT1.</p>Fórmula:C30H22N4O3Pureza:98%Forma y color:SolidPeso molecular:486.52NSC756093
CAS:<p>NSC756093 potentially inhibits GBP1:PIM1 interaction. NSC756093 can be used in ovarian cancer studies.</p>Fórmula:C20H19NO4Pureza:99.92%Forma y color:SolidPeso molecular:337.37HA-1004 dihydrochloride
CAS:<p>HA-1004 dihydrochloride is an inhibitor of PKA, PKC, cGKI, MYLK, and calcium channel protein</p>Fórmula:C12H16ClN5O2SPureza:98%Forma y color:White Crystalline SolidPeso molecular:329.81MS67
CAS:<p>MS67 selectively degrades WDR5 with a 63 nM Kd, has anticancer effects, and is inactive against other protein classes.</p>Fórmula:C52H59F4N9O7SForma y color:SolidPeso molecular:1030.14KP-544
CAS:<p>KP-544 is an agent of neurotrophin potentiator.</p>Fórmula:C18H19ClN4OPureza:98%Forma y color:SolidPeso molecular:342.82CBP/p300-IN-19 hydrochloride
CAS:<p>CBP/p300-IN-19 HCl is a p300/CBP HAT inhibitor (IC50: p300 1.4 μM, CBP 2.2 μM) with antitumor properties.</p>Fórmula:C30H28ClN3O3Forma y color:SolidPeso molecular:514.02KT-531
CAS:<p>KT-531 (KT531) is a highly potent and selective HDAC6 inhibitor with an IC50 value of 8.5 nM and is 39-fold more selective against other HDAC isoenzymes.</p>Fórmula:C17H14F4N2O4SForma y color:SolidPeso molecular:418.36KDM2A/7A-IN-1
CAS:<p>KDM2A/7A-IN-1 is a KDM2A/7A inhibitor with potential anti-tumour activity for the study of duodenal adenomas and ossifying fibromucoid tumours.</p>Fórmula:C33H38N4OPureza:99.59%Forma y color:SolidPeso molecular:506.68Bisegliptin
CAS:<p>Bisegliptin(KRP-104) is a small molecule compound with anti-diabetic activity.</p>Fórmula:C18H26FN3O3Pureza:98%Forma y color:SolidPeso molecular:351.42UNC8153 TFA
CAS:<p>UNC8153 is a NSD2-specific histone-lysine N-methyltransferase degrader, showing selective activity towards NSD2 over NSD1 and NSD3 at 20 µM, and demonstrating a</p>Fórmula:C35H38F3N5O7Pureza:96.44%Forma y color:SolidPeso molecular:697.7GNE-955
CAS:<p>GNE-955 is a potent and orally active inhibitor of pan Pim kinase (Kis: 0.018, 0.11, 0.08 nM for Pim1, Pim2, Pim3, respectively).</p>Fórmula:C22H24N8OPureza:98%Forma y color:SolidPeso molecular:416.48Nezulcitinib
CAS:<p>Nezulcitinib (TD-0903) is an inhaled pan-JAK inhibitor targeting COVID-19-related acute lung injury.</p>Fórmula:C30H37N7O2Forma y color:SolidPeso molecular:527.66SIRT5 inhibitor 7
CAS:<p>SIRT5 inhibitor 7 , a substrate-competitive and selective SIRT5 inhibitor, significantly attenuated renal dysfunction and pathological damage in AKI mice.</p>Fórmula:C28H32ClN7O3SPureza:99.77%Forma y color:SolidPeso molecular:582.12GNE-207
CAS:<p>GNE-207 is a selective and orally bioavailable inhibitor of the bromodomain of CBP (IC50: 1 nM).</p>Fórmula:C29H30N6O3Pureza:98%Forma y color:SolidPeso molecular:510.59FT895
CAS:<p>FT895 is a selective and potent HDAC11 inhibitor with antifungal and antitumor activity that inhibits HDAC11 expression and limits EV71 replication in vitro.</p>Fórmula:C16H15F3N4O2Pureza:98.95% - >99.99%Forma y color:SolidPeso molecular:352.31NHWD-870
CAS:<p>NHWD-870 selectively inhibits BET bromodomains BRD2-4, BRDT; potent anti-cancer effect by inducing apoptosis, halting cell growth.</p>Fórmula:C29H29N7OPureza:98%Forma y color:SolidPeso molecular:491.59T-448 free base
CAS:<p>T-448 free base is a specific, orally active and irreversible lysine-specific demethylase 1 (LSD1, an H3K4 demethylase) inhibitor(IC50 of 22 nM).</p>Fórmula:C17H20N4OSPureza:98%Forma y color:SolidPeso molecular:328.43Ginsenoside Rk1
CAS:<p>Ginsenoside Rk1 is a component created by processing the ginseng plant at high temperatures.</p>Fórmula:C42H70O12Pureza:98.46% - 99.13%Forma y color:SolidPeso molecular:767(S)-Ro 32-0432
CAS:<p>(S)-Ro 32-0432 is a potent, selective inhibitor of protein kinase C (PKC) and G protein-coupled receptor kinase 5 (GRK5), demonstrating ATP-competitive and oral activity. It presents IC50 values of 9.3 nM for PKCα, 28 nM for PKCβI, 30 nM for PKCβII, 36.5 nM for PKCγ, and 108.3 nM for PKCε, showcasing its effectiveness against multiple PKC isoforms. Additionally, (S)-Ro 32-0432 inhibits T-cell activation, indicating its potential application in the research of chronic inflammatory and autoimmune diseases [1] [2].</p>Fórmula:C28H29ClN4O2Forma y color:SolidPeso molecular:489.01HDAC6/HSP90-IN-1
CAS:<p>HDAC6/HSP90-IN-1 is a potent dual inhibitor of HDAC6 and HSP90 with IC50s 4.3 nM & 46.8 nM, respectively; curbs PD-L1 and tumor growth in H1975 mice.</p>Fórmula:C28H37N3O6Forma y color:SolidPeso molecular:511.61QC6352
CAS:<p>QC6352 is a selective and effective KDM4C inhibitor (IC50: 35 nM).</p>Fórmula:C24H25N3O2Pureza:98%Forma y color:SolidPeso molecular:387.47GNE-049
CAS:<p>GNE-049 is a highly selective CBP inhibitor (IC50=1.1 nM) that blocks prostate cancer cell proliferation.</p>Fórmula:C27H32F2N6O2Pureza:98.67%Forma y color:SolidPeso molecular:510.58JAK-IN-4
CAS:<p>JAK-IN-4 is a prodrug of a JAK inhibitor, effective in murine collagen induced arthritis model.</p>Fórmula:C18H21N4Na2O6PPureza:98%Forma y color:SolidPeso molecular:466.341PIM1-IN-1
CAS:<p>PIM1-IN-1 inhibits PIM1/3 with IC50s: PIM1 (7 nM), PIM2 (5530 nM), PIM3 (70 nM); it has anti-cancer properties.</p>Fórmula:C25H30N8O2Pureza:98%Forma y color:SolidPeso molecular:474.56CM-579 trihydrochloride (1846570-40-8 free base)
<p>CM-579 trihydrochloride is a first-in-class reversible and dual inhibitor of G9a and DNMT (IC50s: 16 nM, 32 nM) with potent in vitro cellular activity in a wide</p>Fórmula:C29H43Cl3N4O3Pureza:98%Forma y color:SolidPeso molecular:602.04
