Cromatina / Epigenética
Los inhibidores de cromatina/epigenética son compuestos que modulan la estructura y función de la cromatina o interfieren con modificaciones epigenéticas, como la metilación del ADN y la modificación de histonas. Estos inhibidores son herramientas esenciales para estudiar la regulación de la expresión génica y el papel de la epigenética en enfermedades como el cáncer, los trastornos neurológicos y las anomalías del desarrollo. Al dirigirse a los procesos epigenéticos, estos inhibidores pueden alterar los patrones de expresión génica y ofrecer nuevas vías terapéuticas. En CymitQuimica, ofrecemos una amplia selección de inhibidores de cromatina/epigenética de alta calidad para apoyar su investigación en biología molecular, genética y epigenética.
Subcategorías de "Cromatina / Epigenética"
Se han encontrado 2235 productos de "Cromatina / Epigenética"
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SC99
CAS:<p>SC99 inhibits JAK2-STAT3, reducing STAT3 genes, platelet activity, and has anti-myeloma, anti-thrombotic effects.</p>Fórmula:C15H8Cl2FN3OPureza:99.56%Forma y color:SolidPeso molecular:336.15BMS-P5
CAS:<p>BMS-P5 is a specific and orally active Peptidylarginine Deiminase 4 (PAD4) inhibitor.</p>Fórmula:C27H33ClN6O2Pureza:99.88%Forma y color:SolidPeso molecular:509.04GSK-J1
CAS:<p>GSK-J1 is a highly potent H3K27 histone demethylase inhibitor with IC50 of 28 nM and 53 nM in cell-free assays for JMJD3 (KDM6B) and UTX (KDM6A), respectively.</p>Fórmula:C22H23N5O2Pureza:99.23% - 99.67%Forma y color:SolidPeso molecular:389.45NCGC00244536
CAS:<p>NCGC00244536 (KDM4B Inhibitor B3) is a potent KDM4B inhibitor (IC50: 10 nM).</p>Fórmula:C25H22N2O2Pureza:97.2% - 99.72%Forma y color:SolidPeso molecular:382.45JW 55
CAS:<p>JW 55 (JW55) is an effective and selective β-catenin signaling pathway inhibitor, works by inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2</p>Fórmula:C25H26N2O5Pureza:99.31% - 99.76%Forma y color:SolidPeso molecular:434.48Rucaparib
CAS:<p>Rucaparib (PF-01367338) is a orally PARP inhibitor and a H6PD inhibitor. Rucaparib exhibits antitumor activity against CRPC. Cost-effective and quality-assured.</p>Fórmula:C19H18FN3OPureza:98.24% - 99.80%Forma y color:SolidPeso molecular:323.36WDR5-0103
CAS:<p>WDR5-0103 (WD-Repeat Protein 5-0103) is an effective and specific WD repeat-containing protein 5 (WDR5) antagonist (Kd: 450 nM).</p>Fórmula:C21H25N3O4Pureza:98% - 99.61%Forma y color:SolidPeso molecular:383.44Glucosamine sulfate
CAS:<p>Glucosamine sulfate (D-Glucosaminesulfate) was extracted from synthetic product;Store the product in sealed, cool and dry condition.</p>Fórmula:C6H13NO5·H2SO4Pureza:99.64%Forma y color:White CrystalPeso molecular:277.25Benzamide
CAS:<p>Benzamide (Amid kyseliny benzoove), an inhibitor of poly(ADP-ribose) polymerase, is a derivative of benzoic acid.</p>Fórmula:C7H7NOPureza:99.66%Forma y color:Colorless Crystals Physical Description White Powder (Ntp 1992)Peso molecular:121.14JNJ-42041935
CAS:<p>JNJ-42041935 (HIF-PHD Inhibitor II) is a potent (pKi = 7.3-7.9), 2-oxoglutarate competitive, reversible, and selective inhibitor of PHD enzymes.</p>Fórmula:C12H6ClF3N4O3Pureza:99.58% - ≥95%Forma y color:SolidPeso molecular:346.65GSK591
CAS:<p>GSK591 (GSK3203591), Alternative Names are EPZ015866, GSK3203591, is a potent selective inhibitor of the arginine methyltransferase PRMT5 (IC50=11 nM).</p>Fórmula:C22H28N4O2Pureza:99.35% - 99.45%Forma y color:SolidPeso molecular:380.48UPF 1069
CAS:<p>UPF 1069 is a specific PARP2 inhibitor ( IC50: 0.3 μM). It is ~27-fold selective against PARP1.</p>Fórmula:C17H13NO3Pureza:98.80% - 99.88%Forma y color:SolidPeso molecular:279.29KG-501
CAS:<p>KG-501 (Naphthol AS-E phosphate) is a cAMP response element-binding protein (CREB) inhibitor(IC50 : 6.89 μM).</p>Fórmula:C17H13ClNO5PPureza:97.81%Forma y color:SolidPeso molecular:377.72IDF-11774
CAS:<p>IDF-11774 is a HIF-1 inhibitor.It reduces hif-1α HRE luciferase activity (IC50 = 3.65 μM).</p>Fórmula:C23H32N2O2Pureza:98.05%Forma y color:SolidPeso molecular:368.51GSK484 hydrochloride
CAS:<p>GSK484 hydrochloride (GTPL8577) is a reversible peptidyl-arginine deiminase 4 (PAD4) inhibitor.Cost-effective and quality-assured.</p>Fórmula:C27H32ClN5O3Pureza:98.32% - 99.62%Forma y color:SolidPeso molecular:510.03HJ-PI01
CAS:<p>HJ-PI01 (HJ-PI01) is a Pim-2 inhibitor. HJ-PI01 (HJ-PI01) induces apoptosis and autophagic cell death in triple-negative human breast cancer.</p>Fórmula:C14H11NO2Pureza:98.92%Forma y color:SolidPeso molecular:225.24TP0463518
CAS:<p>TP-0463518 is a highly potent HIF prolyl hydroxylase (PHD) inhibitor (IC50s: 13 nM and 18 nM for human and rat PHD2, respectively).</p>Fórmula:C20H18ClN3O6Pureza:99.52%Forma y color:SolidPeso molecular:431.83Chlorogenic Acid
CAS:<p>Chlorogenic acid is a natural phenol. Chlorogenic acid has anti-inflammatory, antitumor, and antimicrobial effects. Cost-effective and quality-assured.</p>Fórmula:C16H18O9Pureza:98.84% - 99.67%Forma y color:SolidPeso molecular:354.31TAK-632
CAS:<p>TAK-632 is a potent pan-Raf inhibitor.</p>Fórmula:C27H18F4N4O3SPureza:98% - 99.5%Forma y color:SolidPeso molecular:554.52PKC-iota inhibitor 1
CAS:<p>PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)</p>Fórmula:C21H22N6OPureza:98.82%Forma y color:SolidPeso molecular:374.44Tazemetostat hydrobromide
CAS:<p>Tazemetostat hydrobromide: potent, selective EZH2 inhibitor; blocks PRC2/wild-type EZH2 (Ki: 2.5 nM) & EZH1 (IC50: 392 nM).</p>Fórmula:C34H45BrN4O4Pureza:99.8%Forma y color:SolidPeso molecular:653.65MR837
CAS:<p>MR837 (NSD2-PWWP1 antagonist 3f) is a NSD2-PWWP1 antagonist.</p>Fórmula:C16H14N2OSPureza:99.77% - 99.85%Forma y color:SolidPeso molecular:282.36ME0328
CAS:<p>ME0328 is a potent and selective PARP inhibitor with IC50 of 0.89 μM for PARP3, about 7-fold selectivity over PARP1.</p>Fórmula:C19H19N3O2Pureza:99.22%Forma y color:SolidPeso molecular:321.37Hinokitiol
CAS:<p>Hinokitiol prevents UVB-caused cell death, boosts antioxidant activity, and hinders breast cancer growth.</p>Fórmula:C10H12O2Pureza:99.49% - 99.67%Forma y color:SolidPeso molecular:164.2GLPG0634 analog
CAS:<p>GLPG0634 analog (GLPG0634 analogue) is a specific JAK1 inhibitor with IC50 of 10/28/810/116 nM for JAK1/2/3 and TYK2, respectively.</p>Fórmula:C23H18N6O2Pureza:99.52% - >99.99%Forma y color:SolidPeso molecular:410.43CCT 137690
CAS:<p>CCT 137690 is a highly specific and oral-available aurora kinase inhibitor, for aurora A(IC50=15 nM ), B(IC50=25 nM) and C(IC50=19 nM).</p>Fórmula:C26H31BrN8OPureza:98.51% - 99.89%Forma y color:SolidPeso molecular:551.48Ilorasertib
CAS:<p>Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).</p>Fórmula:C25H21FN6O2SPureza:96.17% - 97.49%Forma y color:SolidPeso molecular:488.54KW-2449
CAS:<p>KW-2449 is a multiple-targeted inhibitor, mostly for Flt3, modestly effective to Bcr-Abl, FGFR1, and Aurora A; little inhibitory on PDGFRβ, IGF-1R, EGFR.</p>Fórmula:C20H20N4OPureza:98.43% - 99.69%Forma y color:SolidPeso molecular:332.4UNC0642
CAS:<p>UNC0642 is an effective and specific G9a/GLP inhibitor (IC50< 2.5 nM).</p>Fórmula:C29H44F2N6O2Pureza:98.75% - 99.5%Forma y color:SolidPeso molecular:546.7NVP-TNKS656
CAS:<p>NVP-TNKS656 (TNKS656) is a highly potent, selective, and orally active TNKS2 inhibitor.</p>Fórmula:C27H34N4O5Pureza:99.59%Forma y color:SolidPeso molecular:494.58BMS-911543
CAS:<p>BMS-911543 is a potent and selective inhibitor of JAK2 with IC50 of 1.1 nM, ~350-, 75- and 65-fold selective to JAK1, JAK3 and TYK2, respectively. Phase 1/2.</p>Fórmula:C23H28N8OPureza:97.69% - 99.98%Forma y color:SolidPeso molecular:432.52PARP1-IN-5 dihydrochloride
CAS:<p>PARP1-IN-5 dihydrochloride: oral, potent PARP-1 inhibitor (IC50=14.7 nM), for cancer research.</p>Fórmula:C25H26Cl2N2O5SPureza:98.01%Forma y color:SolidPeso molecular:537.46Ro 31-8220 Mesylate
CAS:<p>Ro 31-8220 Mesylate (Bisindolylmaleimide IX mesylate) is a pan-PKC inhibitor, and also shows potent inhibition against MSK1, MAPKAP-K1b, S6K1, and GSK3β.</p>Fórmula:C25H23N5O2S·CH4O3SPureza:98.79% - 99.02%Forma y color:SolidPeso molecular:553.65Fedratinib hydrochloride hydrate
CAS:<p>Fedratinib hydrochloride hydrate (SAR 302503 hydrochloride hydrate) is a potent, selective, ATP-competitive and orally active JAK2 inhibitor.</p>Fórmula:C27H40Cl2N6O4SPureza:98.96% - 99.87%Forma y color:SolidPeso molecular:615.61PF-06651600 malonate
CAS:<p>PF-06651600 is a potent and selective JAK3 inhibitor.</p>Fórmula:C18H23N5O5Forma y color:SolidPeso molecular:389.41PF-06726304
CAS:<p>PF-06726304: potent EZH2 inhibitor, effective against tumors, Kis at 0.7 nM (wild-type) and 3.0 nM (Y641N mutant).</p>Fórmula:C22H21Cl2N3O3Pureza:98.19% - 99.51%Forma y color:SolidPeso molecular:446.33BRD4770
CAS:<p>BRD4770 is a histone methyltransferase G9a inhibitor and induces cell senescence.</p>Fórmula:C25H23N3O3Pureza:99.82%Forma y color:SolidPeso molecular:413.47Rucaparib tartrate
CAS:<p>Rucaparib tartrate: oral PARP-1/2/3 inhibitor, Ki=1.4 nM; also inhibits H6PD; for studying CRPC.</p>Fórmula:C23H24FN3O7Forma y color:SolidPeso molecular:473.457PFI-3
CAS:<p>PFI-3 is a selective chemical inhibitor for SMARCA (2/4) (Kd = 89 nM)and PBI (5) bromodomains which may result in the delay and prevention of breast cancer.</p>Fórmula:C19H19N3O2Pureza:99.58% - 99.94%Forma y color:SolidPeso molecular:321.37PIN1 inhibitor API-1
CAS:<p>API-1 is a Pin1 inhibitor (IC50: 72.3 nM), enhancing anticancer miRNA biogenesis and inhibiting hepatocellular carcinoma.</p>Fórmula:C15H13F3N6O2Pureza:98.48%Forma y color:SolidPeso molecular:366.3UNC 669
CAS:<p>UNC 669 is an effective and specific MBT (malignant brain tumor) inhibitor with IC50 of 4.2/3.1 uM for L3MBTL1/3.</p>Fórmula:C15H20BrN3OPureza:97.38%Forma y color:SolidPeso molecular:338.24Windorphen
CAS:<p>Windorphen is a Wnt inhibitor that selectively abrogates the Wnt signaling.</p>Fórmula:C17H15ClO3Pureza:99.66%Forma y color:SolidPeso molecular:302.75AG490
CAS:<p>AG490 inhibits EGFR (0.1 μM IC50), 135x > selective than ErbB2, blocks JAK2, spares Lyn, Lck, Syk, Btk, Src.</p>Fórmula:C17H14N2O3Pureza:98.6% - 99.39%Forma y color:Yellow SolidPeso molecular:294.3AT-9283 HCl
CAS:<p>AT-9283, a multi-targeted kinase inhibitor, is used potentially for the treatment of multiple myeloma.</p>Fórmula:C19H24ClN7O2Forma y color:SolidPeso molecular:417.89DL-α-Hydroxyglutaric acid disodium salt
CAS:<p>DL-α-Hydroxyglutaric acid disodium salt (disodium 2-hydroxypentanedioate) is an α -hydroxyacid formed from the hydrolysis of (R) -5-oxy-2-tetrahydrofuran</p>Fórmula:C5H6Na2O5Pureza:≥98%Forma y color:SolidPeso molecular:192.08Filgotinib
CAS:<p>Filgotinib (GLPG0634) is a selective JAK1 inhibitor. The IC50 values against JAK1, JAK2, JAK3, and TYK2 are 10 nM, 28 nM, 810 nM, and 116 nM, respectively.</p>Fórmula:C21H23N5O3SPureza:98.03% - ≥95%Forma y color:SolidPeso molecular:425.5OG-L002
CAS:<p>OG-L002 is an effective and selective LSD1 inhibitor (IC50: 20 nM), showing 69- and 36-fold selectivity over MAO-A and MAO-B, respectively.</p>Fórmula:C15H15NOPureza:97.05% - 98.62%Forma y color:SolidPeso molecular:225.29DMOG
CAS:<p>DMOG (Dimethyloxalylglycine), an antagonist of the α-ketoglutarate cofactor, is an inhibitor for HIF prolyl hydroxylase.</p>Fórmula:C6H9NO5Pureza:80.23% - 99.98%Forma y color:SolidPeso molecular:175.14DR2313
CAS:<p>DR2313 is a competitive inhibitor of poly(ADP-ribose) polymerase (IC50: 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). It also has neuroprotective.</p>Fórmula:C8H10N2OSPureza:98.65%Forma y color:SolidPeso molecular:182.24γ-Oryzanol
CAS:<p>γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the</p>Fórmula:C40H58O4Pureza:mixture - mixtureForma y color:White Or White Crystalline Powder OdourlessPeso molecular:602.9Danusertib
CAS:<p>Danusertib (PHA-739358) is a small-molecule 3-aminopyrazole derivative with potential antineoplastic activity.</p>Fórmula:C26H30N6O3Pureza:97.88% - 98.79%Forma y color:White PowderPeso molecular:474.55BRD4 Inhibitor 30
CAS:<p>4-(2-fluorophenyl)-1,3-thiazol-2-one: has anti-inflammatory, antibacterial, antifungal, and antitumor properties.</p>Fórmula:C9H6FNOSPureza:99.68%Forma y color:SolidPeso molecular:195.21AZ9482
CAS:<p>AZ9482, a potent PARP inhibitor with 2-piperazinyl-3-cyano-pyridine linkage, causes centrosome declustering in HeLa cells with an EC50 < 18 nM.</p>Fórmula:C26H22N6O2Pureza:99.18% - 99.86%Forma y color:SolidPeso molecular:450.49Piribedil hydrochloride
CAS:<p>Piribedil HCl treats Parkinson's, circulatory issues, aids cancer research; inhibits MLL1; D2/D3 agonist; α2-antagonist. EC50: 0.18 μM.</p>Fórmula:C16H19ClN4O2Forma y color:SolidPeso molecular:334.8MM-102 TFA
CAS:<p>MM-102 TFA is a potent WDR5/MLL inhibitor with IC50 of 2.4 nM; it disrupts MLL1-WDR5 interaction, impeding H3K4 HMT activity.</p>Fórmula:C37H50F5N7O6Pureza:99.4% - 99.78%Forma y color:SolidPeso molecular:783.83I-BRD9
CAS:<p>I-BRD9 (GSK602) is the first selective cellular inhibitor for BRD9 with pIC50 of 7.3.</p>Fórmula:C22H22F3N3O3S2Pureza:98.16% - 99.51%Forma y color:SolidPeso molecular:497.55Amodiaquine hydrochloride
CAS:<p>Amodiaquine dihydrochloride: 4-aminoquinoline antimalarial, histamine N-methyltransferase inhibitor (Ki 18.6 nM), Nurr1 agonist, anti-inflammatory.</p>Fórmula:C20H24Cl3N3OForma y color:SolidPeso molecular:428.78WM-8014
CAS:<p>WM-8014 (MOZ-IN-3) is an inhibitor of MOZ(IC50=55 nM), a member of histone acetyltransferases.</p>Fórmula:C20H17FN2O3SPureza:99.64%Forma y color:SolidPeso molecular:384.42G007-LK
CAS:<p>G007-LK is a selective inhibitor of TNKS1 and TNKS2, with IC50s of 46 nM and 25 nM, respectively.</p>Fórmula:C25H16ClN7O3SPureza:97.63% - 98.17%Forma y color:SolidPeso molecular:529.96Remodelin hydrobromide
CAS:<p>Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.</p>Fórmula:C15H15BrN4SPureza:97.22% - 99.84%Forma y color:SolidPeso molecular:363.275JQKD82
CAS:<p>JQKD82 is a selective inhibitor of KDM5 and increases H3K4me3. JQKD82 can be used in studies about the treatment of multiple myeloma.</p>Fórmula:C27H40N4O5Pureza:100.00%Forma y color:SolidPeso molecular:500.632,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
CAS:<p>2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity and physicochemical properties.</p>Fórmula:C16H13Cl2N3O2Pureza:98.77%Forma y color:SolidPeso molecular:350.21,2-Dipalmitoyl-sn-glycerol
CAS:<p>1,2-Dipalmitoyl-sn-glycerol ((S)-1,2-Dipalmitin) is an analog of the PKC-activating second messenger diacylglycerol (DAG). It weakly activates PKC.</p>Fórmula:C35H68O5Pureza:97.84% - 99.78%Forma y color:SolidPeso molecular:568.91Atractylenolide I
CAS:<p>Atractylenolide-I reduces inflammation, improves sepsis, liver, and kidney function, and enhances EOC cell sensitivity to paclitaxel.</p>Fórmula:C15H18O2Pureza:97.55% - 99.92%Forma y color:SolidPeso molecular:230.3MPT0G211 mesylate
CAS:<p>MPT0G211 mesylate: potent, selective HDAC6 inhibitor (IC50=0.291nM), oral, BBB-penetrating, anti-tau and metastasis, potential anticancer.</p>Fórmula:C18H19N3O5SForma y color:SolidPeso molecular:389.43CPI203
CAS:<p>CPI203 (CPI 203) is an effective BET bromodomain inhibitor (IC50: 37 nM for BRD4).</p>Fórmula:C19H18ClN5OSPureza:99.13% - 99.77%Forma y color:SolidPeso molecular:399.9WHI-P97
CAS:<p>WHI-P97 is a rationally designed potent inhibitor of JAK-3.</p>Fórmula:C16H13Br2N3O3Pureza:99.93%Forma y color:SolidPeso molecular:455.1ZM-447439
CAS:<p>ZM 447439 selectively inhibits Aurora A/B (IC50: 110/130 nM); 8x less effective on MEK1, Src, Lck; minimal impact on CDK1/2/4, Plk1, Chk1.</p>Fórmula:C29H31N5O4Pureza:99.11% - 99.59%Forma y color:Pale Yellow SolidPeso molecular:513.59GN44028
CAS:<p>GN44028 is a HIF-1 inhibitor with an IC50 of 14 nM, stopping HIF-1α activity but not mRNA or protein levels, or dimerization.</p>Fórmula:C18H15N3O2Pureza:99.52%Forma y color:SolidPeso molecular:305.33Pacritinib
CAS:<p>Pacritinib (SB1518) (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, in cell-free assays).</p>Fórmula:C28H32N4O3Pureza:99.25% - 99.49%Forma y color:SolidPeso molecular:472.58Pyridone 6
CAS:<p>Pyridone 6, a selective JAK1/2/3 and Tyk2 inhibitor with IC50s: JAK1=15 nM, JAK2=1 nM, JAK3 (Ki=5 nM), Tyk2=1 nM; weakly binds other kinases (130 nM-10 μM).</p>Fórmula:C18H16FN3OPureza:97.1% - 98.74%Forma y color:SolidPeso molecular:309.34Phthalazinone pyrazole
CAS:<p>Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.</p>Fórmula:C18H15N5OPureza:97.03%Forma y color:SolidPeso molecular:317.34JQ-1 (carboxylic acid)
CAS:<p>JQ-1 (carboxylic acid) is a cell-permeable BRD4 inhibitor with IC50s of 77 nM for BRD4(1) and 33 nM for BRD4(2)</p>Fórmula:C19H17ClN4O2SPureza:99.14% - 99.9%Forma y color:SolidPeso molecular:400.88MRTX-1719
CAS:<p>MRTX-1719 is a potent and selective inhibitor of the PRMT5/MTA complex with an IC50 value of <10 nM against PRMT5/MTAMTAPDELSDMA cell lines.Cost-effective and quality-assured.</p>Fórmula:C23H18ClFN6O2Pureza:98.27% - 99.18%Forma y color:SolidPeso molecular:464.88Bisindolylmaleimide IV
CAS:<p>Bisindolylmaleimide IV is a protein kinase C (PKC) cell permeable inhibitor( IC50 : 0.10 - 0.55 μM)</p>Fórmula:C20H13N3O2Pureza:98.83%Forma y color:Dark Red SolidPeso molecular:327.341,5-Isoquinolinediol
CAS:<p>1,5-Isoquinolinediol, a PARP1 inhibitor (IC50: 0.39 μM), is used in DNA repair and cell death studies.</p>Fórmula:C9H7NO2Pureza:98.29% - 99.35%Forma y color:Of White To White PowderPeso molecular:161.16FM-381
CAS:<p>FM381, a JAK3 inhibitor with 127 pM IC50, is 410-3600x more selective over JAK1/2/TYK2.</p>Fórmula:C24H24N6O2Pureza:98.44%Forma y color:SolidPeso molecular:428.49AZ6102
CAS:<p>AZ6102: Potent TNKS1/2 inhibitor, 100x selective over PARPs, IC50 = 5 nM in DLD-1 Wnt pathway.</p>Fórmula:C25H28N6OPureza:97.98% - 99.91%Forma y color:SolidPeso molecular:428.53666-15
CAS:<p>666-15 is a selective CREB inhibitor with an IC50 of 81 nM. 666-15 can effectively inhibit the growth of breast cancer.Cost-effective and quality-assured.</p>Fórmula:C33H31Cl2N3O5Pureza:99.41% - 99.88%Forma y color:SolidPeso molecular:620.52TCS7010
CAS:<p>TCS7010 (Aurora A Inhibitor I) is a novel, potent, and selective inhibitor of Aurora A with IC50 of 3.4 nM in a cell-free assay.</p>Fórmula:C31H31ClFN7O2Pureza:98.49% - 99.62%Forma y color:SolidPeso molecular:588.07Upadacitinib
CAS:<p>Upadacitinib (ABT-494), a selective JAK1 inhibitor, is researched for autoimmune diseases; IC50: 43 nM.</p>Fórmula:C17H19F3N6OPureza:98.96% - 99.94%Forma y color:SolidPeso molecular:380.37OAC1
CAS:<p>OAC1 (BAS 00287861) activates Oct4, boosts iPSC efficiency, and speeds up reprogramming.</p>Fórmula:C14H11N3OPureza:99.49% - 99.65%Forma y color:SolidPeso molecular:237.26Fraxinellone
CAS:<p>1.</p>Fórmula:C14H16O3Pureza:99.35% - 99.92%Forma y color:SolidPeso molecular:232.27WHI-P97 HCl
<p>WHI-P97 HCl is a potent and selective JAK-3 inhibitor.</p>Fórmula:C16H14Br2ClN3O3Pureza:99.49%Forma y color:SolidPeso molecular:491.56Nicotinamide Hydrochloride
CAS:<p>Nicotinamide Hydrochloride, a vitamin B3 form, inhibits SIRT2 and melanoma growth, enhancing NAD+, ATP, ROS, and survival in melanoma mice.</p>Fórmula:C6H7ClN2OForma y color:SolidPeso molecular:158.59SGC-SMARCA-BRDVIII
CAS:<p>SGC-SMARCA-BRDVIII is a potent and selective inhibitor of SMARCA2, SMARCA4, PB1(2), PB1(3) and PB1(5) with Kds of 35 nM, 36 nM, 3.7 μM, 2.0 μM and 13 nM,</p>Fórmula:C19H25N5O3Pureza:99.54% - 99.92%Forma y color:SolidPeso molecular:371.43BD750
CAS:<p>BD750 is an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation(IC50 of 1.5 μM and 1.1 μM in</p>Fórmula:C14H13N3OSPureza:99.02%Forma y color:SolidPeso molecular:271.34Pim1/AKK1-IN-1
CAS:<p>Pim1/AKK1-IN-1: LKB1/AAK1 inhibitor with Kd 35/53/75/380 nM for Pim1/AKK1/MST2/LKB1, also targets MPSK1, TNIK.</p>Fórmula:C20H13N5OPureza:97.03% - 98.69%Forma y color:SolidPeso molecular:339.35PJ34 hydrochloride
CAS:<p>PJ34 hydrochloride (PJ34 HCl) is a potent specific inhibitor of PARPl/2.</p>Fórmula:C17H18ClN3O2Pureza:98.87% - ≥95%Forma y color:SolidPeso molecular:331.8Hispidulin
CAS:<p>Hispidulin, a natural flavone with a broad spectrum of biological activities, is a Pim-1 inhibitor (IC50: 2.71 μM).</p>Fórmula:C16H12O6Pureza:98.53% - 99.87%Forma y color:SolidPeso molecular:300.26Iniparib
CAS:<p>Iniparib (BSI-201) (BSI-201) , a PARP1 inhibitor, exhibits potency in triple-negative breast Y (TNBC).</p>Fórmula:C7H5IN2O3Pureza:98.93%Forma y color:SolidPeso molecular:292.03Perindopril
CAS:<p>Perindopril, an ACE inhibitor, treats hypertension, heart failure, and coronary artery disease; available as arginine or erbumine.</p>Fórmula:C19H32N2O5Forma y color:White PowderPeso molecular:368.47SAR-20347
CAS:<p>SAR-20347 is an inhibitor of TYK2, JAK1/2/3 (IC50: 0.6/23/26/41 nM).</p>Fórmula:C21H18ClFN4O4Pureza:98.99% - 99.77%Forma y color:SolidPeso molecular:444.84MK-8617
CAS:<p>MK-8617 is an orally available HIF PHD1 3 pan-inhibitor, inhibiting PHD1/2/3 (IC50: 1.0/1.0/14 nM).</p>Fórmula:C24H21N5O4Pureza:99.38% - >99.99%Forma y color:SolidPeso molecular:443.45ABBV-744
CAS:<p>ABBV-744 is a BDII-selective BET bromodomain inhibitor that inhibits BRD2/3/4. It is used in the research on inflammatory diseases, cancer, and AIDS.</p>Fórmula:C28H30FN3O4Pureza:97.03% - >99.99%Forma y color:SolidPeso molecular:491.55RK-287107
CAS:<p>RK-287107 is an effective and specific inhibitor of tankyrase (IC50s: 14.3 and 10.6 nM for tankyrase-1 and tankyrase-2, respectively).</p>Fórmula:C22H26F2N4O2Pureza:99.64%Forma y color:SolidPeso molecular:416.46EED226
CAS:<p>EED226 is a potent, selective, and orally bioavailable embryonic ectoderm development (EED) inhibitor with an IC50 of 22 nM.</p>Fórmula:C17H15N5O3SPureza:98.14% - 99.33%Forma y color:SolidPeso molecular:369.4CPI-637
CAS:<p>CPI-637 is a selective and cell-active benzodiazepinone CBP/EP300 bromodomain inhibitor.</p>Fórmula:C22H22N6OPureza:99.89% - 99.95%Forma y color:SolidPeso molecular:386.45Anacardic Acid
CAS:<p>Anacardic Acid (6-pentadecylsalicylic Acid) is an effective inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases.</p>Fórmula:C22H36O3Pureza:97.47% - 99.87%Forma y color:SolidPeso molecular:348.52
