Cromatina / Epigenética
Los inhibidores de cromatina/epigenética son compuestos que modulan la estructura y función de la cromatina o interfieren con modificaciones epigenéticas, como la metilación del ADN y la modificación de histonas. Estos inhibidores son herramientas esenciales para estudiar la regulación de la expresión génica y el papel de la epigenética en enfermedades como el cáncer, los trastornos neurológicos y las anomalías del desarrollo. Al dirigirse a los procesos epigenéticos, estos inhibidores pueden alterar los patrones de expresión génica y ofrecer nuevas vías terapéuticas. En CymitQuimica, ofrecemos una amplia selección de inhibidores de cromatina/epigenética de alta calidad para apoyar su investigación en biología molecular, genética y epigenética.
Subcategorías de "Cromatina / Epigenética"
Se han encontrado 2235 productos de "Cromatina / Epigenética"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
MI-503
CAS:<p>MI-503 is an efficient and selective Menin-MLL inhibitor. MI-503 has a significant inhibitory effect on human MLL leukemia cell line. Cost-effective and quality-assured.</p>Fórmula:C28H27F3N8SPureza:99.87% - 99.99%Forma y color:SolidPeso molecular:564.63Tubacin
CAS:<p>Tubacin is a highly potent and selective, reversible, cell-permeable HDAC6 inhibitor with an IC50 of 4 nM, approximately 350-fold selectivity over HDAC1.</p>Fórmula:C41H43N3O7SPureza:97.62% - 98.75%Forma y color:SolidPeso molecular:721.86SETDB1-TTD-IN-1 TFA
<p>SETDB1-TTD-IN-1 TFA: potent, selective SETDB1-TTD inhibitor (Kd: 88 nM), useful for related biological research.</p>Fórmula:C30H32F3N5O4Forma y color:SolidPeso molecular:583.6BYK204165
CAS:<p>BYK204165 (RT-017290) is a potent PARP inhibitor (PARP1; IC50 = 44.67 nM for human recombinant PARP1 in an enzyme assay)</p>Fórmula:C15H12N2O2Pureza:99.61%Forma y color:SolidPeso molecular:252.27J-147
CAS:<p>J-147, a curcumin derivative, is an experimental drug with reported effects against both Alzheimer's disease and ageing in mouse models of accelerated aging.</p>Fórmula:C18H17F3N2O2Pureza:99.61% - >99.99%Forma y color:SolidPeso molecular:350.33Alobresib
CAS:<p>Alobresib (Vorolanib) is an inhibitor of BET bromodomain,is an antineoplastic drug candidate.</p>Fórmula:C26H23N5O2Pureza:97.63%Forma y color:SolidPeso molecular:437.495-AIQ
CAS:<p>5-aminoisoquinolin-1(2H)-one is the inhibitor of calf thymus PARP1.</p>Fórmula:C9H8N2OPureza:95.95%Forma y color:SolidPeso molecular:160.17BAZ1A-IN-1
CAS:<p>BAZ1A-IN-1, a potent inhibitor, KD 0.52 μM against BAZ1A, is effective in high-BAZ1A cancer cells, not in low-BAZ1A ones.</p>Fórmula:C16H12N4O3SPureza:99.87%Forma y color:SolidPeso molecular:340.36Ruxolitinib (S enantiomer)
CAS:<p>Ruxolitinib S enantiomer (INCB18424) is the S-enantiomer of Ruxolitinib. Ruxolitinib is the first potent, selective JAK1/2 inhibitor.</p>Fórmula:C17H18N6Pureza:99.37% - 99.79%Forma y color:SolidPeso molecular:306.36ML367
CAS:<p>ML367 inhibits ATAD5 stabilization with low micromolar activity, serving as a probe molecule.</p>Fórmula:C19H12F2N4Pureza:99.39%Forma y color:SolidPeso molecular:334.32I-CBP112
CAS:<p>I-CBP112 is a specific and potent acetyl-lysine competitive protein-protein interaction inhibitor targeting the CBP/p300 bromodomains.</p>Fórmula:C27H36N2O5Pureza:98.18%Forma y color:SolidPeso molecular:468.59CPI-455
CAS:<p>CPI-455 is a specific KDM5 inhibitor.</p>Fórmula:C16H14N4OPureza:97.87% - 99.03%Forma y color:SolidPeso molecular:278.31Momelotinib HCl
CAS:<p>Momelotinib HCl is a JAK1/2 inhibitor, reducing anemia in myelofibrosis (MF) patients.</p>Fórmula:C23H24Cl2N6O2Forma y color:SolidPeso molecular:487.38BCI-121
CAS:<p>BCI-121 is a substrate-competitive SMYD3 inhibitor that inhibits the proliferation of the cancer cell.</p>Fórmula:C14H18BrN3O2Pureza:99.67%Forma y color:SolidPeso molecular:340.22SGC2085 HCl
CAS:<p>SGC2085: potent, selective CARM1 inhibitor; IC50=50 nM; >100x selectivity vs other PRMTs; impacts cancer growth.</p>Fórmula:C19H24N2O2·HClPureza:99.91%Forma y color:SolidPeso molecular:348.87Splitomicin
CAS:<p>Splitomicin (1-Naphthalenepropanoic Acid) (IC50 of 60 μM), a specific inhibitor of NAD(+)-dependent histone deacetylase Sir2p, displays a high activity in a</p>Fórmula:C13H10O2Pureza:97.09% - 99.11%Forma y color:SolidPeso molecular:198.224-Phenylbutyric acid
CAS:<p>4-Phenylbutyric acid (Benzenebutyric acid) is a HDAC inhibitor and an endoplasmic reticulum stress (ERS) inhibitor. Cost-effective and quality-assured.</p>Fórmula:C10H12O2Pureza:98.40% - 99.76%Forma y color:SolidPeso molecular:164.2Gandotinib
CAS:<p>LY2784544(Gandotinib (LY2784544)) is a potent JAK2 inhibitor (IC50: 3 nM), effective in JAK2V617F(Ki: 0.245 nM).</p>Fórmula:C23H25ClFN7OPureza:99.33% - 99.86%Forma y color:SolidPeso molecular:469.94Protein kinase inhibitor 6
CAS:<p>Protein kinase inhibitor 6 is a protein kinase inhibitor.</p>Fórmula:C13H9FN2SPureza:98.01%Forma y color:SolidPeso molecular:244.29Iso-H7 dihydrochloride
CAS:<p>Iso-H7 dihydrochloride is a less potent inhibitor of phosphokinase C than H-7.</p>Fórmula:C14H19Cl2N3O2SPureza:99.53%Forma y color:White Crystalline SolidPeso molecular:364.29dencichine
CAS:<p>Dencichine (ODAP) is a neurotoxic agent and a haemostatic agent, which relates to modulation of the coagulation system, and fibrinolytic system.</p>Fórmula:C5H8N2O5Pureza:99.93% - ≥95%Forma y color:SolidPeso molecular:176.13Cerdulatinib
CAS:<p>Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.</p>Fórmula:C20H27N7O3SPureza:98.74% - 99.49%Forma y color:SolidPeso molecular:445.543-TYP
CAS:<p>3-TYP (3-(1H-1,2,3-triazol-4-yl) pyridine) is a selective SIRT3 inhibitor.</p>Fórmula:C7H6N4Pureza:99.16% - >99.99%Forma y color:SolidPeso molecular:146.15Nudifloramide
CAS:<p>Nudifloramide (1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide) is one of the end degradation products of nicotinamide-adenine dinucleotide (NAD).</p>Fórmula:C7H8N2O2Pureza:99.7% - ≥95%Forma y color:SolidPeso molecular:152.15M1001
CAS:<p>M1001 is a HIF-2α agonist.</p>Fórmula:C17H17N3O2SPureza:98.83%Forma y color:SolidPeso molecular:327.4Mivebresib
CAS:<p>Mivebresib (ABBV-075) is a potent BET inhibitor with antitumor effects, disrupting gene expression and MYC, TMPRSS2-ETS proteins.</p>Fórmula:C22H19F2N3O4SPureza:98.74% - 99.32%Forma y color:SolidPeso molecular:459.47GSK467
CAS:<p>GSK467 is a potent and selective inhibitor of KDM5 (JARID1)(Ki : 10 nM).</p>Fórmula:C17H13N5O2Pureza:99.55%Forma y color:SolidPeso molecular:319.32MG 149
CAS:<p>MG 149 (Tip60 HAT inhibitor) is a selective and potent Tip60 inhibitor with IC50 of 74 uM, similar potentcy for MOF(IC50= 47 uM).</p>Fórmula:C22H28O3Pureza:98.69% - 99.86%Forma y color:SolidPeso molecular:340.46Amifostine trihydrate
CAS:<p>Amifostine trihydrate (WR2721) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin.</p>Fórmula:C5H15N2O3PS·3H2OPureza:99.71% - 99.80%Forma y color:SolidPeso molecular:268.27Tofacitinib Citrate
CAS:<p>Tofacitinib Citrate (CP-690550 citrate) is a a potent, cell-permeable inhibitor of JAK1/2/3 (IC50s: 1/20/112 nM).</p>Fórmula:C22H28N6O8Pureza:99.19% - 99.75%Forma y color:SolidPeso molecular:504.49DDP-38003 trihydrochloride
<p>DDP-38003 trihydrochloride is a novel, orally available histone lysine-specific demethylase 1A (KDM1A/LSD1) inhibitor with an IC50 of 84 nM.</p>Fórmula:C21H29Cl3N4OPureza:98%Forma y color:SolidPeso molecular:459.84WHI-P154
CAS:<p>WHI-P154 (Jak3 inhibitor ii) is a potent JAK3 inhibitor.</p>Fórmula:C16H14BrN3O3Pureza:98% - 99.67%Forma y color:SolidPeso molecular:376.2Selisistat
CAS:<p>Selisistat (EX-527) is a potent and specific inhibitor of the deacetylase SIRT1 (IC50=38 nM).</p>Fórmula:C13H13ClN2OPureza:98.53% - 99.94%Forma y color:SolidPeso molecular:248.71Fedratinib
CAS:<p>Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3.</p>Fórmula:C27H36N6O3SPureza:97.31% - 99.96%Forma y color:SolidPeso molecular:524.68BI 2536
CAS:<p>BI2536 is an effective Plk1 inhibitor (IC50: 0.83 nM). It has 4- and 11-fold greater selectivity than Plk2 and Plk3.</p>Fórmula:C28H39N7O3Pureza:98% - 99.88%Forma y color:SolidPeso molecular:521.65(+)-JQ-1
CAS:<p>(+)-JQ-1 (JQ1) is a BET bromine domain inhibitor that inhibits BRD4 (1/2) (IC50=77/33 nM) with specificity and reversibility.</p>Fórmula:C23H25ClN4O2SPureza:97.57% - ≥95%Forma y color:SolidPeso molecular:456.99Niraparib tosylate
CAS:<p>Niraparib tosylate (MK-4827 (tosylate))(with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.</p>Fórmula:C19H20N4O·C7H8O3SPureza:99.34% - 99.87%Forma y color:SolidPeso molecular:492.59AZD-2461
CAS:<p>AZD2461 is a novel PARP inhibitor.</p>Fórmula:C22H22FN3O3Pureza:98% - 99.87%Forma y color:SolidPeso molecular:395.43Acetyl Pentapeptide-1 acetate
<p>Acetyl Pentapeptide-1 acetate is an histone deacetylase inhibitor.</p>Fórmula:C34H55N9O12Pureza:99.09%Forma y color:SolidPeso molecular:781.86Bobcat339
CAS:<p>Bobcat339 is a novel cytosine-based TET enzyme inhibitor (IC50s: 33/73 uM for TET1/2), but not DNMT3a, does not inhibit the DNA methyltransferase DNMT3a.</p>Fórmula:C16H12ClN3OPureza:97.79% - 99.24%Forma y color:SolidPeso molecular:297.74Methyl L-histidinate dihydrochloride
CAS:<p>The inhibitory effect of Methyl L-histidinate dihydrochloride (L-Histidine methyl ester dihydrochloride) on histidine decarboxylase in Sprague-Dawley rat</p>Fórmula:C7H13Cl2N3O2Pureza:99.74%Forma y color:White To Off-White PowderPeso molecular:242.1A-196
CAS:<p>A-196 is a potent and selective inhibitor of SUV420 h1 and SUV420 h2 with IC50 values of 0.025 and 0.144 μM, respectively; more than 100-fold selective over</p>Fórmula:C18H16Cl2N4Pureza:99.92%Forma y color:SolidPeso molecular:359.25PFI-1
CAS:<p>PFI-1 (PF-6405761), a specific BET (bromodomain-containing protein) inhibitor for BRD4, is with the IC50 of 0.22 μM in a cell-free assay.</p>Fórmula:C16H17N3O4SPureza:98.74% - 99.19%Forma y color:SolidPeso molecular:347.39Isoxazole
CAS:<p>Isoxazole (1,2-oxazole) is the inhibitor of acetylcholinesterase (AChE). The ligands of Isoxazole bind to and inhibit the Sxc- antiporter.</p>Fórmula:C3H3NOPureza:99.34%Forma y color:Colorless LiquidPeso molecular:69.06Baricitinib phosphate
CAS:<p>Baricitinib phosphate (INCB028050) is a selective orally bioavailable JAK1/JAK2 inhibitor.</p>Fórmula:C16H20N7O6PSPureza:99.4% - 99.82%Forma y color:SolidPeso molecular:469.41Aurora kinase inhibitor-2
CAS:<p>Aurora kinase inhibitor-2 (IUN-70219) is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A (IC50 = 0.39 M).</p>Fórmula:C23H20N4O3Pureza:98.66%Forma y color:SolidPeso molecular:400.435-Ph-IAA
CAS:<p>5-Ph-IAA is a derivative of Indole-3-acetic acid (IAA), which is a plant hormone and acts as an enzyme or prodrug combination for cancer gene therapy.</p>Fórmula:C16H13NO2Pureza:99.37% - 99.973%Forma y color:SolidPeso molecular:251.28WHI-P97 HCl
<p>WHI-P97 HCl is a potent and selective JAK-3 inhibitor.</p>Fórmula:C16H14Br2ClN3O3Pureza:99.49%Forma y color:SolidPeso molecular:491.56Hesperadin
CAS:<p>Hesperadin(IC50=250 nM) effectively inhibits Aurora B.</p>Fórmula:C29H32N4O3SPureza:98.04% - 99.44%Forma y color:SolidPeso molecular:516.652-hexyl-4-Pentynoic Acid
CAS:<p>2-hexyl-4-Pentynoic Acid, a valproic acid (VPA) derivatives, is a potent and robust HDACs inhibitor with IC50 value of 13 μM.</p>Fórmula:C11H18O2Pureza:98%Forma y color:SolidPeso molecular:182.26
