Daño al ADN / Reparación del ADN
Los inhibidores de daño/ reparación del ADN son compuestos que interfieren con los procesos involucrados en la detección y reparación de daños en el ADN. Estos inhibidores son fundamentales para estudiar los mecanismos de estabilidad genómica, mutagénesis y respuesta al daño del ADN. También son importantes en la investigación del cáncer, ya que muchos tumores dependen de vías específicas de reparación del ADN para sobrevivir. Al inhibir estas vías, los inhibidores de daño/reparación del ADN pueden aumentar la eficacia de la quimioterapia y la radioterapia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de daño/reparación del ADN de alta calidad para apoyar su investigación en biología molecular, oncología y farmacología.
Subcategorías de "Daño al ADN / Reparación del ADN"
- ATM / ATR(71 productos)
- Alquilación de ADN(21 productos)
- ADN metiltransferasa(459 productos)
- ADN girasa(6 productos)
- ADN-PK(50 productos)
- MTH1(1 productos)
- Antimetabolito / análogo nucleósido(503 productos)
- Transcriptasa inversa(41 productos)
- Sirtuin(90 productos)
- Telomerasa(33 productos)
- Topoisomerasa(127 productos)
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Se han encontrado 844 productos para "Daño al ADN / Reparación del ADN".
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Epitalon
CAS:Epithalon (Epitalon) is a synthetic pineal peptide analog of epithalamin with potential applications in anti-aging and longevity research.Fórmula:C14H22N4O9Pureza:99.97%Forma y color:SolidPeso molecular:390.35Balaglitazone
CAS:Balaglitazone is a PPARγ agonist that regulates blood glucose and is used in studies of heart failure and myocardial infarction.Fórmula:C20H17N3O4SPureza:99.74%Forma y color:SolidPeso molecular:395.43(R)-(+)-Bay-K-8644
CAS:(R)-(+)-Bay-K-8644, a Ca2+ channel agonist, is a dihydropyridine agonist that induces central respiratory depression and inhibits platelet activation in cats.Fórmula:C16H15F3N2O4Pureza:96.51% - 96.57%Forma y color:SolidPeso molecular:356.3CP-868388 free base
CAS:CP-868388 free base (CP-868388) is a PPARα agonist with hypolipidemic and anti-inflammatory activity and is used in the study of dyslipidemia.Fórmula:C26H33NO5Pureza:99.84%Forma y color:White SolidPeso molecular:439.54Bleomycin A2
CAS:Bleomycin A2 is an antibiotic that promotes DNA degradation and is also an AspH inhibitor (IC50 = 1.47 μM), with anti-tumor activity.Fórmula:C55H85N17O25S4Forma y color:White SolidPeso molecular:1512.62VK-1727
VK-1727 inhibits EBNA1 DNA binding, reducing proliferation of EBV-positive cells while sparing EBV-negative cells, useful for multiple sclerosis research.Fórmula:C29H25NO4Pureza:98.07%Forma y color:Yellow SolidPeso molecular:451.51Banoxantrone dihydrochloride
CAS:Banoxantrone dihydrochloride (AQ4N dihydrochloride) is a novel hypoxic cytotoxin that selectively kills hypoxic cells through an iNOS-dependent mechanism.Fórmula:C22H30Cl2N4O6Pureza:99.88%Forma y color:Black SolidPeso molecular:517.4Ref: TM-T10459
5mg74,00€10mg92,00€1mL*10mM (DMSO)92,00€25mg157,00€50mg222,00€100mg329,00€500mg788,00€Trovafloxacin (Standard)
CAS:Trovafloxacin (Standard) is the standard substance of Trovafloxacin, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Trovafloxacin is a broad-spectrum quinolone antibiotic with potent activity against Gram-positive.Fórmula:C20H15F3N4O3Forma y color:SolidPeso molecular:416.35Ifosfamide (Standard)
CAS:Ifosfamide (Standard) is the standard substance of Ifosfamide, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Ifosfamide (NSC-109724) alkylates and forms DNA crosslinks, thereby preventing DNA strand separation and DNA replication. Ifosfamide is a synthetic analog of the nitrogen mustard cyclophosphamide with antineoplastic activity. This agent is a prodrug that must be activated through hydroxylation by hepatic microsomal enzymes.Fórmula:C7H15Cl2N2O2PForma y color:SolidPeso molecular:261.09O6BTG-octylglucoside
CAS:O6BTG-octylglucoside is a potent O6-methylguanine-DNAmethyl-transferase (MGMT) inhibitor (IC50s: 10 nM and 32 nM in HeLa S3 cells and in vitro (cell extracts)).Fórmula:C24H34BrN5O7SPureza:98%Forma y color:SolidPeso molecular:616.53Phytanic acid
CAS:Phytanic acid serves as a functional metabolic tool specifically designed to enable the precise detection of peroxisomal dysfunction and the investigation of AMACR-mediated metabolic pathways which play pivotal roles in the progression of prostate cancer and various dysmorphic syndromes during strictly monitored laboratory observation periods and molecular investigations to evaluate the pharmacological impact of branched-chain fatty acid accumulation in specialized preclinical research environments.Fórmula:C20H40O2Pureza:99.77%Forma y color:White SolidPeso molecular:312.53(R)-GSK-3685032
CAS:(R)-GSK-3685032 is a selective, reversible DNMT1 inhibitor, non-covalent, IC50: 0.036 μM; reduces DNA methylation, inhibits cancer growth.Fórmula:C22H24N6OSForma y color:SolidPeso molecular:420.54Gancaonin L
CAS:Gancaonin L is a natural product that can be used as a reference standard. The CAS number of Gancaonin L is 129145-50-2.Fórmula:C20H18O6Forma y color:SolidPeso molecular:354.3589-Hydroxyellipticin free base
CAS:9-hydroxyellipticine is a potent cytotoxic and antitumor agent. 9-hydroxyellipticine is a 9-hydroxy derivative of ellipticine.Fórmula:C17H14N2OForma y color:SolidPeso molecular:262.31Heptaplatin
CAS:Heptaplatin, an anticancer platinum compound, counters many cancers, including cisplatin-resistant types, with a 17% response rate and tolerable toxicity.Fórmula:C11H20N2O6PtForma y color:SolidPeso molecular:471.36PPARγ agonist 5
CAS:PPARγ agonist 5 is a selective and potent PPARγ agonist that has shown research potential for cancer disease.Fórmula:C33H31N5OForma y color:SolidPeso molecular:513.63Phosphoramide mustard cyclohexanamine
CAS:Phosphoramide mustard cyclohexanamine is active metabolite of cyclophosphamide, an alkylating agent that cross-links DNA strands,causes cell death, antitumor.Fórmula:C10H24Cl2N3O2PPureza:95%Forma y color:SolidPeso molecular:320.20Gatifloxacin mesylate
CAS:Gatifloxacin mesylate, a 4th-gen fluoroquinolone antibiotic, inhibits DNA gyrase and topoisomerase IV.Fórmula:C20H26FN3O7SPureza:98%Forma y color:SolidPeso molecular:471.5Miriplatin
CAS:Miriplatin (SM-11355) (SM-11355) is a platinum complex used in TACE that has promise for the therapy of hepatocellular carcinoma (HCC).Fórmula:C34H68N2O4PtPureza:≥95%Forma y color:SolidPeso molecular:763.99CM-579 trihydrochloride
CM-579 trihydrochloride: reversible G9a/DNMT inhibitor with IC50s 16 nM (G9a) & 32 nM (DNMT); potent against various cancer cells.Fórmula:C29H43Cl3N4O3Forma y color:SolidPeso molecular:602.04
