Daño al ADN / Reparación del ADN
Los inhibidores de daño/ reparación del ADN son compuestos que interfieren con los procesos involucrados en la detección y reparación de daños en el ADN. Estos inhibidores son fundamentales para estudiar los mecanismos de estabilidad genómica, mutagénesis y respuesta al daño del ADN. También son importantes en la investigación del cáncer, ya que muchos tumores dependen de vías específicas de reparación del ADN para sobrevivir. Al inhibir estas vías, los inhibidores de daño/reparación del ADN pueden aumentar la eficacia de la quimioterapia y la radioterapia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de daño/reparación del ADN de alta calidad para apoyar su investigación en biología molecular, oncología y farmacología.
Subcategorías de "Daño al ADN / Reparación del ADN"
- ATM / ATR(71 productos)
- Alquilación de ADN(21 productos)
- ADN metiltransferasa(459 productos)
- ADN girasa(6 productos)
- ADN-PK(50 productos)
- MTH1(1 productos)
- Antimetabolito / análogo nucleósido(503 productos)
- Transcriptasa inversa(41 productos)
- Sirtuin(90 productos)
- Telomerasa(33 productos)
- Topoisomerasa(127 productos)
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Se han encontrado 844 productos para "Daño al ADN / Reparación del ADN".
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PI-3065
CAS:PI-3065 is a novel potent and selective PI3K p110δ inhibitor.Fórmula:C27H31FN6OSPureza:99.84% - ≥95%Forma y color:SolidPeso molecular:506.64PI-103
CAS:PI-103 is a potent, cell-permeable, ATP-competitive inhibitor of PI3K family members (IC50s: 2/3/3/15/30/23 nM for p110α/β/δ/γ, mTOR, and DNA-PK).Fórmula:C19H16N4O3Pureza:97.79% - 99.30%Forma y color:Yellow SolidPeso molecular:348.36Ceralasertib
CAS:Ceralasertib (AZD6738) is an ATR kinase inhibitor (IC50=1 nM) with selective and oral activity. Ceralasertib has antitumor activity. Cost effective and quality assured.Fórmula:C20H24N6O2SPureza:98% - 99.99%Forma y color:White SolidPeso molecular:412.51Niraparib tosylate
CAS:Niraparib tosylate (MK-4827 (tosylate))(with IC50 of 3.8 nM/2.1 nM) is a selective PARP1/PARP2 inhibitor.Fórmula:C19H20N4O·C7H8O3SPureza:98.19% - 99.34%Forma y color:SolidPeso molecular:492.592-Iodoacetamide
CAS:Iodoacetamide, an alkylating agent, is commonly utilized for cysteine alkylation in proteomics sample preparation.Fórmula:C2H4INOPureza:98.54% - 99.95%Forma y color:Yellow SolidPeso molecular:184.96Pirinixic Acid
CAS:Pirinixic Acid (NSC 310038) is a synthetic thiacetic acid derivative used in biomedical research, a peroxisome proliferator that activates specific PPAR.Fórmula:C14H14ClN3O2SPureza:98.27% - 99.92%Forma y color:SolidPeso molecular:323.8Ref: TM-T2269
1mL*10mM (DMSO)44,00€10mg46,00€25mg60,00€50mg74,00€100mg100,00€200mg140,00€500mg225,00€1g333,00€T0070907
CAS:T0070907(IC50=1 nM) , an effective and specific PPARγ inhibitor, with the >800-fold selectivity over PPARα and PPARδ.Fórmula:C12H8ClN3O3Pureza:98.25% - 99.98%Forma y color:SolidPeso molecular:277.66Ref: TM-T6689
5mg50,00€1mL*10mM (DMSO)52,00€10mg55,00€25mg96,00€50mg140,00€100mg187,00€200mg243,00€500mg408,00€Triazavirin
CAS:Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.Fórmula:C5H7N6NaO5SPureza:99.55%Forma y color:SolidPeso molecular:286.2Adelmidrol
CAS:Adelmidrol is an anti-inflammatory ethanolamide derivative of azelaic acid.Fórmula:C13H26N2O4Pureza:99.35% - 99.73%Forma y color:White SolidPeso molecular:274.36G3335 Acetate
G3335 Acetate was discovered to be a novel PPARgamma antagonist.Fórmula:C18H23N3O7Pureza:99.75%Forma y color:SolidPeso molecular:393.39KU60019
CAS:Ku-60019 is a potent, reversible inhibitor of ATM kinase (IC50: 6.3 nM). It is much less effective or without effect against a panel of 229 other kinases.Fórmula:C30H33N3O5SPureza:95.9% - 99.7%Forma y color:Yellow SolidPeso molecular:547.67KCC-07
CAS:KCC-07: Selective, potent, brain-penetrant MBD2 inhibitor with anticancer effects, blocking MBD2-DNA binding and activating BAI1 signaling.Fórmula:C14H11N3OSPureza:98.86% - 99.01%Forma y color:SolidPeso molecular:269.32Ref: TM-T8554
1mg35,00€5mg71,00€1mL*10mM (DMSO)73,00€10mg112,00€25mg212,00€50mg335,00€100mg500,00€200mg712,00€Choline Fenofibrate
CAS:Choline Fenofibrate (Trilipix) is a choline formulation of fenofibrate, a synthetic phenoxy-isobutyric acid derivate and prodrug with antihyperlipidemicFórmula:C22H28ClNO5Pureza:98.82%Forma y color:SolidPeso molecular:421.91Razoxane
CAS:Razoxane is used as an antimitotic agent with immunosuppressive properties.Fórmula:C11H16N4O4Pureza:99.75%Forma y color:SolidPeso molecular:268.27Lobeglitazone
CAS:Lobeglitazone (CKD-501) is a dual PPARα/γ agonist thiazolidinedione antidiabetic that enhances insulin sensitivity.Fórmula:C24H24N4O5SForma y color:SolidPeso molecular:480.54L-165041
CAS:L-165041 is a potent and selective agonist of the nuclear receptor PPARβ and PPARδ(Ki = 9 nM, EC50 = ~500 nM ,respectively)Fórmula:C22H26O7Pureza:97.97%Forma y color:SolidPeso molecular:402.44Lonazolac
CAS:Lonazolac is a nonsteroidal anti-inflammatory drug[1].Fórmula:C17H13ClN2O2Pureza:99.40%Forma y color:White SolidPeso molecular:312.75Elimusertib
CAS:Elimusertib (BAY-1895344) is a potent, highly selective and orally available ATR inhibitor with an IC50 of 7 nM.Elimusertib shows potent anti-tumor efficacy inFórmula:C20H21N7OPureza:98.72% - 99.98%Forma y color:Yellow SolidPeso molecular:375.43Ref: TM-T7318
1mg34,00€5mg74,00€1mL*10mM (DMSO)82,00€10mg105,00€25mg205,00€50mg340,00€100mg532,00€500mg1.144,00€SCR7 pyrazine
CAS:SCR7 pyrazine (SCR7) enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ).Fórmula:C18H12N4OSPureza:98.72% - 99.85%Forma y color:SolidPeso molecular:332.38Ref: TM-T1724
1mg37,00€2mg52,00€5mg74,00€1mL*10mM (DMSO)74,00€10mg114,00€25mg244,00€50mg386,00€100mg557,00€Samotolisib
CAS:Samotolisib (LY3023414) inhibits PI3K, DNA-PK, mTOR; tested for solid tumors including breast and colon cancer.Fórmula:C23H26N4O3Pureza:98.41% - 99.69%Forma y color:SolidPeso molecular:406.48
