Daño al ADN / Reparación del ADN
Los inhibidores de daño/ reparación del ADN son compuestos que interfieren con los procesos involucrados en la detección y reparación de daños en el ADN. Estos inhibidores son fundamentales para estudiar los mecanismos de estabilidad genómica, mutagénesis y respuesta al daño del ADN. También son importantes en la investigación del cáncer, ya que muchos tumores dependen de vías específicas de reparación del ADN para sobrevivir. Al inhibir estas vías, los inhibidores de daño/reparación del ADN pueden aumentar la eficacia de la quimioterapia y la radioterapia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de daño/reparación del ADN de alta calidad para apoyar su investigación en biología molecular, oncología y farmacología.
Subcategorías de "Daño al ADN / Reparación del ADN"
- ATM / ATR(71 productos)
- Alquilación de ADN(11 productos)
- ADN metiltransferasa(422 productos)
- ADN girasa(11 productos)
- ADN-PK(50 productos)
- MTH1(1 productos)
- Antimetabolito / análogo nucleósido(1.388 productos)
- Transcriptasa inversa(43 productos)
- Sirtuin(88 productos)
- Telomerasa(33 productos)
- Topoisomerasa(136 productos)
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Se han encontrado 963 productos de "Daño al ADN / Reparación del ADN"
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(R)-GSK-3685032
CAS:<p>(R)-GSK-3685032 is a selective, reversible DNMT1 inhibitor, non-covalent, IC50: 0.036 μM; reduces DNA methylation, inhibits cancer growth.</p>Fórmula:C22H24N6OSForma y color:SolidPeso molecular:420.54Gatifloxacin mesylate
CAS:<p>Gatifloxacin mesylate, a 4th-gen fluoroquinolone antibiotic, inhibits DNA gyrase and topoisomerase IV.</p>Fórmula:C20H26FN3O7SPureza:98%Forma y color:SolidPeso molecular:471.5Daun02
CAS:<p>Daun02 is the topoisomerase inhibitor Daunorubicin prodrug.</p>Fórmula:C41H44N2O20Pureza:98%Forma y color:SolidPeso molecular:884.79AMA-37
CAS:<p>AMA-37 is a selective, reversible, and ATP-competitive DNA-PK inhibitor.</p>Fórmula:C17H17NO3Pureza:98%Forma y color:SolidPeso molecular:283.329-Hydroxyellipticin free base
CAS:<p>9-hydroxyellipticine is a potent cytotoxic and antitumor agent. 9-hydroxyellipticine is a 9-hydroxy derivative of ellipticine.</p>Fórmula:C17H14N2OForma y color:SolidPeso molecular:262.31Phosphoramide mustard cyclohexanamine
CAS:<p>Phosphoramide mustard cyclohexanamine is active metabolite of cyclophosphamide, an alkylating agent that cross-links DNA strands,causes cell death, antitumor.</p>Fórmula:C10H24Cl2N3O2PPureza:95%Forma y color:SolidPeso molecular:320.2RPR121056
CAS:RPR121056 is a Irinotecan metabolite, which is generated by CYP3A4. Irinotecan is an antineoplastic agent that inhibits topoisomerase type I.Fórmula:C33H38N4O8Pureza:98%Forma y color:SolidPeso molecular:618.68Gatifloxacin sesquihydrate
CAS:<p>Gatifloxacin sesquihydrate, a bacterial DNA gyrase inhibitor, is used to treat tuberculosis and pneumonia.</p>Fórmula:C19H24FN3O5Forma y color:SolidPeso molecular:393.41Telomerase-IN-3
CAS:<p>Telomerase-IN-3 is an inhibitor of telomerase.</p>Fórmula:C19H16ClN5O3Pureza:98%Forma y color:SolidPeso molecular:397.82Rucaparib
CAS:<p>Rucaparib (PF-01367338) is a orally PARP inhibitor and a H6PD inhibitor. Rucaparib exhibits antitumor activity against CRPC. Cost-effective and quality-assured.</p>Fórmula:C19H18FN3OPureza:98.24% - 99.80%Forma y color:SolidPeso molecular:323.36Pentamidine isethionate
CAS:<p>Pentamidine isethionate (Pentamidine diisethionate) is a synthetic amidine derivative, Pentamidine Isethionate is an antiprotozoal and antifungal agent.</p>Fórmula:C23H36N4O10S2Pureza:98% - 99.83%Forma y color:Slight Butyric Odor Very Bitter Taste Ph (5% Aqueous Solution) 4 5-6 5 (Ntp 1992)Peso molecular:592.68YK-3-237
CAS:YK-3-237 (B-[2-Methoxy-5-[(1E)-3-oxo-3-(3,4,5-trimethoxyphenyl)-1-propen-1-yl]phenyl]boronic acid) reduces acetylation of mtp53 and exhibits anti-proliferativeFórmula:C19H21BO7Pureza:99.47%Forma y color:SolidPeso molecular:372.18Pixantrone dimaleate
CAS:<p>Pixantrone dimaleate (Pixantrone Maleate) (BBR 2778 dimaleate) is an experimental antineoplastic drug.</p>Fórmula:C25H27N5O10Pureza:98.70% - 99.11%Forma y color:SolidPeso molecular:557.21BCH001
CAS:<p>BCH001 is a specific small-molecule inhibitor of PAPD5.</p>Fórmula:C20H15F3N2O5Pureza:99.06%Forma y color:SolidPeso molecular:420.34PTGR2-IN-1
CAS:<p>PTGR2-IN-1 is a potent inhibito of PTGR2r. PTGR2-IN-1 increases 15-keto-PGE2-dependent PPARγ transcriptional activity in PTGR2-transfected HEK293T cells.</p>Fórmula:C19H22N2O2Pureza:99.13%Forma y color:SolidPeso molecular:310.39NU2058
CAS:<p>NU2058 (O(6)-Cyclohexylmethylguanine) is a guanine-based CDK inhibitor, also inhibits DNA topoisomerase II ATPase activity.</p>Fórmula:C12H17N5OPureza:99.34% - 99.92%Forma y color:SolidPeso molecular:247.3L-778123 hydrochloride
CAS:<p>The L-778123 hydrochloride is an inhibitor of FPTase (IC50: 2 nM) and GGPTase-I (IC50: 98 nM) in enzyme inhibition determination.</p>Fórmula:C22H21Cl2N5OPureza:93.93% - 98.51%Forma y color:SolidPeso molecular:442.34BYK204165
CAS:<p>BYK204165 (RT-017290) is a potent PARP inhibitor (PARP1; IC50 = 44.67 nM for human recombinant PARP1 in an enzyme assay)</p>Fórmula:C15H12N2O2Pureza:99.61%Forma y color:SolidPeso molecular:252.27Ciprofloxacin hydrochloride monohydrate
CAS:<p>Ciprofloxacin hydrochloride monohydrate (Bay-09867 hydrochloride monohydrate) is a fluoroquinolone antibiotic with potent antibacterial activity.</p>Fórmula:C17H21ClFN3O4Pureza:99.23% - 99.85%Forma y color:White Or Yellowish Crystalline PowderPeso molecular:385.82AK-7
CAS:<p>AK-7 is a brain-permeable SIRT2 inhibitor and to characterize its cholesterol-reducing properties in neuronal models with an IC50 of 15.5 μM.</p>Fórmula:C19H21BrN2O3SPureza:98.43% - 99.34%Forma y color:SolidPeso molecular:437.35
