Daño al ADN / Reparación del ADN
Los inhibidores de daño/ reparación del ADN son compuestos que interfieren con los procesos involucrados en la detección y reparación de daños en el ADN. Estos inhibidores son fundamentales para estudiar los mecanismos de estabilidad genómica, mutagénesis y respuesta al daño del ADN. También son importantes en la investigación del cáncer, ya que muchos tumores dependen de vías específicas de reparación del ADN para sobrevivir. Al inhibir estas vías, los inhibidores de daño/reparación del ADN pueden aumentar la eficacia de la quimioterapia y la radioterapia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de daño/reparación del ADN de alta calidad para apoyar su investigación en biología molecular, oncología y farmacología.
Subcategorías de "Daño al ADN / Reparación del ADN"
- ATM / ATR(71 productos)
- Alquilación de ADN(11 productos)
- ADN metiltransferasa(422 productos)
- ADN girasa(11 productos)
- ADN-PK(50 productos)
- MTH1(1 productos)
- Antimetabolito / análogo nucleósido(1.388 productos)
- Transcriptasa inversa(43 productos)
- Sirtuin(88 productos)
- Telomerasa(33 productos)
- Topoisomerasa(136 productos)
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Se han encontrado 962 productos de "Daño al ADN / Reparación del ADN"
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CM-579 trihydrochloride
<p>CM-579 trihydrochloride: reversible G9a/DNMT inhibitor with IC50s 16 nM (G9a) & 32 nM (DNMT); potent against various cancer cells.</p>Fórmula:C29H43Cl3N4O3Forma y color:SolidPeso molecular:602.04Pyridostatin TFA
CAS:<p>Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-</p>Fórmula:C37H35F9N8O11Pureza:97.09% - 99.84%Forma y color:SolidPeso molecular:938.71Trovafloxacin
CAS:<p>Trovafloxacin, a broad-spectrum quinolone antibiotic, exhibits potent activity against Gram-positive bacteria.</p>Fórmula:C20H15F3N4O3Pureza:99.21% - 99.27%Forma y color:SolidPeso molecular:416.35Dxd
CAS:<p>Dxd (OQM5SD32BQ) is a potent DNA topoisomerase I inhibitor (IC50= 0.31 μM). Dxd was used as a conjugate drug for HER2-targeted ADCs. High-Quality, Low-Cost!</p>Fórmula:C26H24FN3O6Pureza:98.21% - ≥98%Forma y color:SolidPeso molecular:493.48Darglitazone Sodium
CAS:<p>Darglitazone Sodium, an oral PPAR-γ agonist, aids type II diabetes study by regulating glucose and lipids.</p>Fórmula:C23H21N2NaO4SForma y color:SolidPeso molecular:444.48BGP-15
CAS:<p>BGP-15 (BGP-15 2HCl) is a PARP inhibitor with protecting effect after ischemia-reperfusion injury.</p>Fórmula:C14H24Cl2N4O2Pureza:98.17% - 99.89%Forma y color:SolidPeso molecular:351.27Zebularine
CAS:<p>Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor.</p>Fórmula:C9H12N2O5Pureza:99.04% - >99.99%Forma y color:SolidPeso molecular:228.2RHPS4
CAS:<p>RHPS4 (RHPS 4 methosulfate) is a potent inhibitor of Telomerase at submicromolar.</p>Fórmula:C22H17F2N2·CH3O4SPureza:99.72%Forma y color:SolidPeso molecular:458.48Rabdosiin
CAS:<p>Rabdosiin ((+)-Rabdosiin) is a natural product, and has anti-allergic activity, anti-HIV activity and inhibition on DNA topoisomerase.</p>Fórmula:C36H30O16Pureza:98.64% - 99.49%Forma y color:SolidPeso molecular:718.61PIK-75 hydrochloride
CAS:<p>PIK-75 hydrochloride (PIK-75 HCl) is a p110α inhibitor, isoform-specific mutants at Ser773, and potently inhibits DNA-PK with IC50 of 2 nM in cell-free assay.</p>Fórmula:C16H14BrN5O4S·HClPureza:97.82%Forma y color:SolidPeso molecular:488.74JW 55
CAS:<p>JW 55 (JW55) is an effective and selective β-catenin signaling pathway inhibitor, works by inhibition of the PARP domain of tankyrase 1 and tankyrase 2 (TNKS1/2</p>Fórmula:C25H26N2O5Pureza:99.31% - 99.76%Forma y color:SolidPeso molecular:434.48Tretazicar
CAS:<p>CB1954, an anticancer prodrug, turns into a potent alkylating agent when activated by NQO2 and EP-0152R.</p>Fórmula:C9H8N4O5Pureza:99.41% - 99.7%Forma y color:SolidPeso molecular:252.18Coralyne chloride
CAS:<p>Coralyne chloride is a protoberberine with strong anticancer activity.</p>Fórmula:C22H22ClNO4Pureza:98.88%Forma y color:SolidPeso molecular:399.87Pixantrone
CAS:<p>Pixantrone has anti-tumor activity that is a DNA intercalator and topoisomerase II inhibitor.</p>Fórmula:C17H19N5O2Forma y color:SolidPeso molecular:325.37AZ20
CAS:<p>AZ20 is an effective and specific inhibitor of ATR kinase (IC50: 5 nM, in a cell-free assay), 8-fold selectivity over mTOR.</p>Fórmula:C21H24N4O3SPureza:98% - 99.69%Forma y color:SolidPeso molecular:412.51NPC 15199
CAS:<p>NPC 15199 (FMOC-L-Leucine) is an anti-inflammatory agent.</p>Fórmula:C21H23NO4Pureza:99.93% - 99.94%Forma y color:White Crystalline PowderPeso molecular:353.41Genz-644282
CAS:<p>Genz-644282, a novel non-camptothecin topoisomerase I inhibitor for cancer treatment.</p>Fórmula:C22H21N3O5Pureza:97.49%Forma y color:SolidPeso molecular:407.42Pentamidine
CAS:<p>Pentamidine is an antifungal and antiprotozoal agent, interacting directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor</p>Fórmula:C19H24N4O2Pureza:98.64% - 99.67%Forma y color:Crystallizes As Colorless Plates From Water SolidPeso molecular:340.42Remodelin hydrobromide
CAS:<p>Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.</p>Fórmula:C15H15BrN4SPureza:97.22% - 99.84%Forma y color:SolidPeso molecular:363.275TIQ-A
CAS:<p>TIQ-A blocks PARP1 to prevent excessive DNA damage response, implicated in ischemia, asthma, and atherosclerosis.</p>Fórmula:C11H7NOSPureza:99.75%Forma y color:SolidPeso molecular:201.24
