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Daño al ADN / Reparación del ADN

Daño al ADN / Reparación del ADN

Los inhibidores de daño/ reparación del ADN son compuestos que interfieren con los procesos involucrados en la detección y reparación de daños en el ADN. Estos inhibidores son fundamentales para estudiar los mecanismos de estabilidad genómica, mutagénesis y respuesta al daño del ADN. También son importantes en la investigación del cáncer, ya que muchos tumores dependen de vías específicas de reparación del ADN para sobrevivir. Al inhibir estas vías, los inhibidores de daño/reparación del ADN pueden aumentar la eficacia de la quimioterapia y la radioterapia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de daño/reparación del ADN de alta calidad para apoyar su investigación en biología molecular, oncología y farmacología.

Subcategorías de "Daño al ADN / Reparación del ADN"

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Se han encontrado 959 productos de "Daño al ADN / Reparación del ADN"

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  • Bendamustine
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    Bendamustine

    CAS:
    <p>Bendamustine (SDX105) for the treatment of Non-Hodgkin Lymphomas and Chronic Lymphocytic Leukemia</p>
    Fórmula:C16H21Cl2N3O2
    Pureza:≥98%
    Forma y color:Solid
    Peso molecular:358.26

    Ref: TM-T8380

  • Genz-644282
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    Genz-644282

    CAS:
    <p>Genz-644282, a novel non-camptothecin topoisomerase I inhibitor for cancer treatment.</p>
    Fórmula:C22H21N3O5
    Pureza:97.49%
    Forma y color:Solid
    Peso molecular:407.42

    Ref: TM-T7187

  • Pentamidine
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    Pentamidine

    CAS:
    <p>Pentamidine is an antifungal and antiprotozoal agent, interacting directly with the pathogen genome by binding to AT-rich regions of duplex DNA and the minor</p>
    Fórmula:C19H24N4O2
    Pureza:98.64% - 99.67%
    Forma y color:Crystallizes As Colorless Plates From Water Solid
    Peso molecular:340.42

    Ref: TM-T23133

  • TIQ-A
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    TIQ-A

    CAS:
    <p>TIQ-A blocks PARP1 to prevent excessive DNA damage response, implicated in ischemia, asthma, and atherosclerosis.</p>
    Fórmula:C11H7NOS
    Pureza:99.75%
    Forma y color:Solid
    Peso molecular:201.24

    Ref: TM-T50098

  • AZD-2461
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    AZD-2461

    CAS:
    <p>AZD2461 is a novel PARP inhibitor.</p>
    Fórmula:C22H22FN3O3
    Pureza:98% - 99.87%
    Forma y color:Solid
    Peso molecular:395.43

    Ref: TM-T2484

  • Dxd
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    Dxd

    CAS:
    <p>Dxd (OQM5SD32BQ) is a potent DNA topoisomerase I inhibitor (IC50= 0.31 μM). Dxd was used as a conjugate drug for HER2-targeted ADCs. High-Quality, Low-Cost!</p>
    Fórmula:C26H24FN3O6
    Pureza:98.21% - ≥98%
    Forma y color:Solid
    Peso molecular:493.48

    Ref: TM-T11249L

  • Pyridostatin
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    Pyridostatin

    CAS:
    <p>Pyridostatin (RR82) is a synthetic small-molecule stabilizer of G-quadruplexes, a secondary structure of DNA that usually exists in the end of the chromosome or</p>
    Fórmula:C31H32N8O5
    Pureza:98%
    Forma y color:Solid
    Peso molecular:596.64

    Ref: TM-T1899

  • TMPyP4 tosylate
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    TMPyP4 tosylate

    CAS:
    <p>TMPyP4 tosylate (TMP 1363) is a quadruplex-specific ligand and is a telomerase inhibitor with antitumor effects in osteosarcoma cell lines.</p>
    Fórmula:C72H66N8O12S4
    Pureza:98.61% - 99.85%
    Forma y color:Solid
    Peso molecular:1363.6

    Ref: TM-T13174

  • UPF 1069
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    UPF 1069

    CAS:
    <p>UPF 1069 is a specific PARP2 inhibitor ( IC50: 0.3 μM). It is ~27-fold selective against PARP1.</p>
    Fórmula:C17H13NO3
    Pureza:98.80% - 99.88%
    Forma y color:Solid
    Peso molecular:279.29

    Ref: TM-T6181

  • KU-57788
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    KU-57788

    CAS:
    <p>NU7441 (KU-57788 (NU7441)) is a highly effective and specific DNA-PK inhibitor (IC50: 14 nM).</p>
    Fórmula:C25H19NO3S
    Pureza:98% - >99.99%
    Forma y color:Solid
    Peso molecular:413.49

    Ref: TM-T6276

  • EDO-S101
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    EDO-S101

    CAS:
    <p>EDO-S101 (Tinostamustine) is a pan HDAC inhibitor with IC50 values of 9, 9 and 25 nM for HDAC1, HDAC2 and HDAC3 , respectively.</p>
    Fórmula:C19H28Cl2N4O2
    Pureza:98.02% - 99.44%
    Forma y color:Solid
    Peso molecular:415.36

    Ref: TM-T3516

  • Thiomyristoyl
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    Thiomyristoyl

    CAS:
    <p>Thiomyristoyl is an effective and selective SIRT2 inhibitor (IC50: 28 nM). It inhibits SIRT1 (IC50: 98 μM) but no effect on SIRT3 even at 200 μM.</p>
    Fórmula:C34H51N3O3S
    Pureza:99.16%
    Forma y color:Solid
    Peso molecular:581.85

    Ref: TM-T3447

  • Trovafloxacin
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    Trovafloxacin

    CAS:
    <p>Trovafloxacin, a broad-spectrum quinolone antibiotic, exhibits potent activity against Gram-positive bacteria.</p>
    Fórmula:C20H15F3N4O3
    Pureza:99.21% - 99.27%
    Forma y color:Solid
    Peso molecular:416.35

    Ref: TM-T13231

  • SCR130
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    SCR130

    CAS:
    <p>SCR130 (1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-) 是基于 SCR7 的 DNA 非同源末端连接抑制剂，可诱导细胞凋亡并，具有抗癌活性。 它特异性依赖连接酶 IV，抑制 DNA 的末端连接。</p>
    Fórmula:C19H13Cl2N3O2S
    Pureza:98.9%
    Forma y color:Solid
    Peso molecular:418.3

    Ref: TM-T9150

  • CC-115 hydrochloride
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    CC-115 hydrochloride

    CAS:
    <p>CC-115 hydrochloride: potent DNA-PK/mTOR inhibitor; IC50s: 13 nM and 21 nM; blocks mTORC1/C2 pathways.</p>
    Fórmula:C16H17ClN8O
    Forma y color:Solid
    Peso molecular:372.82

    Ref: TM-T61505

  • PARP1-IN-5 dihydrochloride 
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    PARP1-IN-5 dihydrochloride 

    CAS:
    <p>PARP1-IN-5 dihydrochloride: oral, potent PARP-1 inhibitor (IC50=14.7 nM), for cancer research.</p>
    Fórmula:C25H26Cl2N2O5S
    Pureza:98.01%
    Forma y color:Solid
    Peso molecular:537.46

    Ref: TM-T9610

  • Remodelin hydrobromide
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    Remodelin hydrobromide

    CAS:
    <p>Remodelin hydrobromide (Remodelin HBR) is a novel potent and selective inhibitor of the acetyl-transferase protein NAT10.</p>
    Fórmula:C15H15BrN4S
    Pureza:97.22% - 99.84%
    Forma y color:Solid
    Peso molecular:363.275

    Ref: TM-T6133

  • Furegrelate
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    Furegrelate

    CAS:
    <p>FUREGRELATE, a thromboxane A2 (TxA2) synthase inhibitor, blunts the development of pulmonary arterial hypertension in neonatal piglets.</p>
    Fórmula:C15H11NO3
    Pureza:99.71%
    Forma y color:Solid
    Peso molecular:253.25

    Ref: TM-T11339L

  • AZ32
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    AZ32

    CAS:
    <p>AZ32 is an orally bioavailable and blood-brain barrier-penetrating ATM inhibitor with an IC50 of &lt;6.2 nM for ATM enzyme, and an IC50 of 0.31 μM for ATM in cell.</p>
    Fórmula:C20H16N4O
    Pureza:98.68% - 99.68%
    Forma y color:Solid
    Peso molecular:328.37

    Ref: TM-T4443

  • AZ9482
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    AZ9482

    CAS:
    <p>AZ9482, a potent PARP inhibitor with 2-piperazinyl-3-cyano-pyridine linkage, causes centrosome declustering in HeLa cells with an EC50 &lt; 18 nM.</p>
    Fórmula:C26H22N6O2
    Pureza:99.18% - 99.86%
    Forma y color:Solid
    Peso molecular:450.49

    Ref: TM-T22264