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Daño al ADN / Reparación del ADN

Daño al ADN / Reparación del ADN

Los inhibidores de daño/ reparación del ADN son compuestos que interfieren con los procesos involucrados en la detección y reparación de daños en el ADN. Estos inhibidores son fundamentales para estudiar los mecanismos de estabilidad genómica, mutagénesis y respuesta al daño del ADN. También son importantes en la investigación del cáncer, ya que muchos tumores dependen de vías específicas de reparación del ADN para sobrevivir. Al inhibir estas vías, los inhibidores de daño/reparación del ADN pueden aumentar la eficacia de la quimioterapia y la radioterapia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de daño/reparación del ADN de alta calidad para apoyar su investigación en biología molecular, oncología y farmacología.

Subcategorías de "Daño al ADN / Reparación del ADN"

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Se han encontrado 958 productos de "Daño al ADN / Reparación del ADN"

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  • EDO-S101
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    EDO-S101

    CAS:
    <p>EDO-S101 (Tinostamustine) is a pan HDAC inhibitor with IC50 values of 9, 9 and 25 nM for HDAC1, HDAC2 and HDAC3 , respectively.</p>
    Fórmula:C19H28Cl2N4O2
    Pureza:98.02% - 99.44%
    Forma y color:Solid
    Peso molecular:415.36

    Ref: TM-T3516

  • SCR130
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    SCR130

    CAS:
    <p>SCR130 (1,7,9-Triazaspiro[4.5]dec-1-ene-6,10-dione, 2,4-bis(4-chlorophenyl)-8-thioxo-) 是基于 SCR7 的 DNA 非同源末端连接抑制剂，可诱导细胞凋亡并，具有抗癌活性。 它特异性依赖连接酶 IV，抑制 DNA 的末端连接。</p>
    Fórmula:C19H13Cl2N3O2S
    Pureza:98.9%
    Forma y color:Solid
    Peso molecular:418.3

    Ref: TM-T9150

  • Topovale
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    Topovale

    CAS:
    <p>Topovale (ARC111) is a potent inhibitor of topoisomerase I.</p>
    Fórmula:C23H23N3O5
    Pureza:99.94%
    Forma y color:Solid
    Peso molecular:421.45

    Ref: TM-T9088

  • PARP1-IN-5 dihydrochloride 
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    PARP1-IN-5 dihydrochloride 

    CAS:
    <p>PARP1-IN-5 dihydrochloride: oral, potent PARP-1 inhibitor (IC50=14.7 nM), for cancer research.</p>
    Fórmula:C25H26Cl2N2O5S
    Pureza:98.01%
    Forma y color:Solid
    Peso molecular:537.46

    Ref: TM-T9610

  • NU6027
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    NU6027

    CAS:
    <p>NU6027 is a potent ATR/CDK inhibitor, inhibits CDK1/2, ATR and DNA-PK with Ki of 2.5 μM/1.3 μM, 0.4 μM and 2.2 μM, enter cells more readily than the 6-</p>
    Fórmula:C11H17N5O2
    Pureza:98.36%
    Forma y color:Solid
    Peso molecular:251.29

    Ref: TM-T6612

  • Furegrelate
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    Furegrelate

    CAS:
    <p>FUREGRELATE, a thromboxane A2 (TxA2) synthase inhibitor, blunts the development of pulmonary arterial hypertension in neonatal piglets.</p>
    Fórmula:C15H11NO3
    Pureza:99.71%
    Forma y color:Solid
    Peso molecular:253.25

    Ref: TM-T11339L

  • AZ32
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    AZ32

    CAS:
    <p>AZ32 is an orally bioavailable and blood-brain barrier-penetrating ATM inhibitor with an IC50 of &lt;6.2 nM for ATM enzyme, and an IC50 of 0.31 μM for ATM in cell.</p>
    Fórmula:C20H16N4O
    Pureza:98.68% - 99.68%
    Forma y color:Solid
    Peso molecular:328.37

    Ref: TM-T4443

  • AZ9482
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    AZ9482

    CAS:
    <p>AZ9482, a potent PARP inhibitor with 2-piperazinyl-3-cyano-pyridine linkage, causes centrosome declustering in HeLa cells with an EC50 &lt; 18 nM.</p>
    Fórmula:C26H22N6O2
    Pureza:99.18% - 99.86%
    Forma y color:Solid
    Peso molecular:450.49

    Ref: TM-T22264

  • DR2313
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    DR2313

    CAS:
    <p>DR2313 is a competitive inhibitor of poly(ADP-ribose) polymerase (IC50: 0.20 and 0.24 μM for PARP-1 and PARP-2 respectively). It also has neuroprotective.</p>
    Fórmula:C8H10N2OS
    Pureza:98.65%
    Forma y color:Solid
    Peso molecular:182.24

    Ref: TM-T22749

  • ME0328
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    ME0328

    CAS:
    <p>ME0328 is a potent and selective PARP inhibitor with IC50 of 0.89 μM for PARP3, about 7-fold selectivity over PARP1.</p>
    Fórmula:C19H19N3O2
    Pureza:99.22%
    Forma y color:Solid
    Peso molecular:321.37

    Ref: TM-T6578

  • γ-Oryzanol
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    γ-Oryzanol

    CAS:
    <p>γ-Oryzanol (Gamma-Oryzanol) is a natural nutrient extract isolated from rice bran oil that contains a mixture of sterols and ferulic acids, which may aid in the</p>
    Fórmula:C40H58O4
    Pureza:mixture - mixture
    Forma y color:White Or White Crystalline Powder Odourless
    Peso molecular:602.9

    Ref: TM-T3606

  • VE-821
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    VE-821

    CAS:
    <p>VE-821 (ATR Inhibitor IV) is a selective ATP competitive inhibitor of ATR( Ki/IC50: 13/26 nM in cell-free assays).</p>
    Fórmula:C18H16N4O3S
    Pureza:97.19% - 99.97%
    Forma y color:Solid
    Peso molecular:368.41

    Ref: TM-T3032

  • Prulifloxacin
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    Prulifloxacin

    CAS:
    <p>Prulifloxacin (NM441) is a broad-spectrum fluoroquinolone that inhibits bacterial DNA synthesis by blocking topoisomerase II and IV.</p>
    Fórmula:C21H20FN3O6S
    Pureza:99.47%
    Forma y color:Yellow Or Slightly Yellow Power
    Peso molecular:461.46

    Ref: TM-T5394

  • Senaparib
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    Senaparib

    CAS:
    <p>Senaparib (IMP4297) is a novel highly potent and selective oral PARP1/2 inhibitor with strong antitumor activity.</p>
    Fórmula:C24H20F2N6O3
    Pureza:99.8%
    Forma y color:Solid
    Peso molecular:478.45

    Ref: TM-T9593

  • Levofloxacin hydrochloride
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    Levofloxacin hydrochloride

    CAS:
    <p>Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity.</p>
    Fórmula:C18H21ClFN3O4
    Pureza:99.78% - 99.98%
    Forma y color:Solid
    Peso molecular:397.8

    Ref: TM-T8747

  • Pirarubicin
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    Pirarubicin

    CAS:
    <p>Pirarubicin (Theprubicin), an anthracycline antibiotic, inhibits DNA/RNA synthesis and is used as an antineoplastic.</p>
    Fórmula:C32H37NO12
    Pureza:97.80% - 99.15%
    Forma y color:Red Crystalline Powder
    Peso molecular:627.64

    Ref: TM-T6628

  • Ganciclovir sodium
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    Ganciclovir sodium

    CAS:
    <p>Ganciclovir sodium, a sodium salt with anti-CMV and HSV-1 antiviral properties.</p>
    Fórmula:C9H13N5NaO4
    Pureza:99.93%
    Forma y color:Solid
    Peso molecular:278.22

    Ref: TM-T22337

  • AZ20
    Targetmol
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    AZ20

    CAS:
    <p>AZ20 is an effective and specific inhibitor of ATR kinase (IC50: 5 nM, in a cell-free assay), 8-fold selectivity over mTOR.</p>
    Fórmula:C21H24N4O3S
    Pureza:98% - 99.69%
    Forma y color:Solid
    Peso molecular:412.51

    Ref: TM-T1958

  • Triazavirin
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    Triazavirin

    CAS:
    <p>Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.</p>
    Fórmula:C5H7N6NaO5S
    Pureza:99.55%
    Forma y color:Solid
    Peso molecular:286.2

    Ref: TM-T8354

  • 9-Hydroxycamptothecin
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    9-Hydroxycamptothecin

    CAS:
    <p>9-Hydroxycampothecin is a camptothecin derivative with anticancer activity.</p>
    Fórmula:C20H16N2O5
    Pureza:98.28%
    Forma y color:Solid
    Peso molecular:364.35

    Ref: TM-T4952