Daño al ADN / Reparación del ADN
Los inhibidores de daño/ reparación del ADN son compuestos que interfieren con los procesos involucrados en la detección y reparación de daños en el ADN. Estos inhibidores son fundamentales para estudiar los mecanismos de estabilidad genómica, mutagénesis y respuesta al daño del ADN. También son importantes en la investigación del cáncer, ya que muchos tumores dependen de vías específicas de reparación del ADN para sobrevivir. Al inhibir estas vías, los inhibidores de daño/reparación del ADN pueden aumentar la eficacia de la quimioterapia y la radioterapia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de daño/reparación del ADN de alta calidad para apoyar su investigación en biología molecular, oncología y farmacología.
Subcategorías de "Daño al ADN / Reparación del ADN"
- ATM / ATR(71 productos)
- Alquilación de ADN(11 productos)
- ADN metiltransferasa(422 productos)
- ADN girasa(11 productos)
- ADN-PK(50 productos)
- MTH1(1 productos)
- Antimetabolito / análogo nucleósido(1.388 productos)
- Transcriptasa inversa(43 productos)
- Sirtuin(88 productos)
- Telomerasa(33 productos)
- Topoisomerasa(136 productos)
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Se han encontrado 963 productos de "Daño al ADN / Reparación del ADN"
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NU 7026
CAS:NU 7026 (DNA-PK Inhibitor II) is an effective DNA-PK inhibitor (IC50: 0.23 μM, in cell-free assays), 60-fold selective for DNA-PK than PI3K and no inhibitionFórmula:C17H15NO3Pureza:99.51% - >99.99%Forma y color:SolidPeso molecular:281.31Trifluridine/tipiracil hydrochloride mixture
CAS:Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a novel oral combination drug containing trifluridine (TFT) and Tipiracil hydrochloride (TTP) in aFórmula:C29H34Cl2F6N8O12Pureza:98% - 99.79%Forma y color:SolidPeso molecular:871.53NKL 22
CAS:<p>NKL 22 (Histone Deacetylase Inhibitor IV) is an effective Histone Deacetylase Inhibitor.</p>Fórmula:C19H23N3O2Pureza:96.16% - 96.24%Forma y color:SolidPeso molecular:325.4Hinokitiol
CAS:Hinokitiol prevents UVB-caused cell death, boosts antioxidant activity, and hinders breast cancer growth.Fórmula:C10H12O2Pureza:99.49% - 99.98%Forma y color:SolidPeso molecular:164.2GSK3685032
CAS:<p>GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM).</p>Fórmula:C22H24N6OSPureza:98.56% - 99.49%Forma y color:SolidPeso molecular:420.53AGK7
CAS:<p>AGK7 is an AGK2 control; it's a less selective SIRT2 inhibitor, with IC50s >5 μM for SIRT3, and >50 μM for SIRT1/2.</p>Fórmula:C23H13Cl2N3O2Pureza:98.31%Forma y color:SolidPeso molecular:434.27TH34
CAS:<p>TH34 is an HDAC6/8/10 inhibitor (IC50s: 4.6/1.9/7.7 μM). It shows high selectivity over HDAC1/2/3.</p>Fórmula:C15H16N2O2Pureza:98.32%Forma y color:SolidPeso molecular:256.3Trovafloxacin
CAS:<p>Trovafloxacin, a broad-spectrum quinolone antibiotic, exhibits potent activity against Gram-positive bacteria.</p>Fórmula:C20H15F3N4O3Pureza:99.21% - 99.27%Forma y color:SolidPeso molecular:416.35BGP-15
CAS:<p>BGP-15 (BGP-15 2HCl) is a PARP inhibitor with protecting effect after ischemia-reperfusion injury.</p>Fórmula:C14H24Cl2N4O2Pureza:98.17% - 99.89%Forma y color:SolidPeso molecular:351.27Deoxycytidine triphosphate
CAS:<p>dCTP is a nucleotide used in DNA synthesis, PCR, cDNA creation, and sequencing.</p>Fórmula:C9H16N3O13P3Pureza:99.68%Forma y color:SolidPeso molecular:467.16MN-64
CAS:<p>MN-64 is a tankyrases inhibitor, showed 6 nM potency against tankyrase 1, isoenzyme selectivity, and Wnt signaling inhibition.</p>Fórmula:C18H16O2Pureza:99.5% - 99.93%Forma y color:SolidPeso molecular:264.32Abacavir sulfate
CAS:<p>Abacavir sulfate (Ziagen) , a nucleoside analogue, effectively utilize its antiviral activity</p>Fórmula:C14H18N6OH2O4SPureza:99.79% - 99.85%Forma y color:White To Off-White SolidPeso molecular:335.38Pyridostatin TFA
CAS:<p>Pyridostatin Trifluoroacetate Salt is a G-quadruplexe stabilizer with Kd of 490 nM in a cell-free assay, which targets a series of proto-oncogenes including c-</p>Fórmula:C37H35F9N8O11Pureza:97.09% - 99.84%Forma y color:SolidPeso molecular:938.71Belotecan hydrochloride
CAS:Belotecan hydrochloride (CKD-602) is a synthetic water-soluble camptothecin derivative and topoisomerase I inhibitor with potential antitumor activityFórmula:C25H28ClN3O4Pureza:99.63% - ≥95%Forma y color:SolidPeso molecular:469.96BRD73954
CAS:<p>BRD73954, an effective and specific HDAC inhibitor, which is with IC50 of 36 nM and 120 nM for HDAC6 and HDAC8, respectively.</p>Fórmula:C16H16N2O3Pureza:99.42% - 99.56%Forma y color:SolidPeso molecular:284.31SRT 1720 dihydrochloride
CAS:<p>SRT 1720 dihydrochloride is a selective activator of SIRT1 (EC1.5: 0.16 μM) and shows less potent activities on SIRT2 (EC1.5: 37 μM) and SIRT3 (EC1.5: 300 μM).</p>Fórmula:C25H25Cl2N7OSPureza:98.58%Forma y color:SolidPeso molecular:542.489-Hydroxycamptothecin
CAS:<p>9-Hydroxycampothecin is a camptothecin derivative with anticancer activity.</p>Fórmula:C20H16N2O5Pureza:98.28%Forma y color:SolidPeso molecular:364.35Marbofloxacin
CAS:<p>Marbofloxacin (Zeniquin) is an effective, broad-spectrum antibiotic of bacterial, which inhibits DNA replication.</p>Fórmula:C17H19FN4O4Pureza:99.76% - 99.84%Forma y color:SolidPeso molecular:362.36E1231
CAS:<p>E1231 is an activator of SIRT1 . E1231 protects from experimental atherosclerosis and lowers plasma cholesterol and triglycerides by enhancing ABCA1 expression.</p>Fórmula:C21H21N3O3Pureza:98.45%Forma y color:SolidPeso molecular:363.41SirReal2
CAS:<p>SirReal2 is a potent and selective Sirt2 inhibitor with IC50 of 140 nM.</p>Fórmula:C22H20N4OS2Pureza:98.96% - 99.75%Forma y color:SolidPeso molecular:420.55
