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Daño al ADN / Reparación del ADN

Daño al ADN / Reparación del ADN

Los inhibidores de daño/ reparación del ADN son compuestos que interfieren con los procesos involucrados en la detección y reparación de daños en el ADN. Estos inhibidores son fundamentales para estudiar los mecanismos de estabilidad genómica, mutagénesis y respuesta al daño del ADN. También son importantes en la investigación del cáncer, ya que muchos tumores dependen de vías específicas de reparación del ADN para sobrevivir. Al inhibir estas vías, los inhibidores de daño/reparación del ADN pueden aumentar la eficacia de la quimioterapia y la radioterapia. En CymitQuimica, ofrecemos una amplia gama de inhibidores de daño/reparación del ADN de alta calidad para apoyar su investigación en biología molecular, oncología y farmacología.

Subcategorías de "Daño al ADN / Reparación del ADN"

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Se han encontrado 959 productos de "Daño al ADN / Reparación del ADN"

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  • BRD4097
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    BRD4097

    CAS:
    <p>BRD4097, a negative control in the HDAC1/2/3/8 assay, is a selective histone deacetylase (HDAC3) inhibitor that can be used to protect b-cells and improve</p>
    Fórmula:C16H17N3O2
    Pureza:99.75%
    Forma y color:Solid
    Peso molecular:283.33

    Ref: TM-T30579

  • BRD2492
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    BRD2492

    CAS:
    <p>BRD2492 is an HDAC1 and HDAC2 inhibitor with antiproliferative activity, inhibits HDAC1/2 and induces apoptosis.</p>
    Fórmula:C20H18N4O2
    Pureza:99.56%
    Forma y color:Solid
    Peso molecular:346.38

    Ref: TM-T26897

  • KRP-101
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    KRP-101

    CAS:
    <p>KRP-101, a PPARɑ agonist, is used potentially for the treatment of diabetes and hyperlipidaemia.</p>
    Fórmula:C26H26FNO5
    Forma y color:Solid
    Peso molecular:451.49

    Ref: TM-T27746

  • PPARγ agonist 7
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    PPARγ agonist 7

    CAS:
    <p>PPARγ agonist 7 (Compound 3a) is a highly potent and selective agonist of the peroxisome proliferator-activated receptor gamma (PPARγ).</p>
    Fórmula:C20H30O6
    Forma y color:Solid
    Peso molecular:366.45

    Ref: TM-T61417

  • K-756
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    K-756

    CAS:
    <p>K-756 is a direct and selective inhibitor of tankyrase (TNKS), which inhibits the ADP-ribosylation activity of TNKS1 (IC50 = 31 nM) and TNKS2 (IC50 = 36 nM).</p>
    Fórmula:C24H27N5O3
    Pureza:99.81%
    Forma y color:Solid
    Peso molecular:433.5

    Ref: TM-T15639

  • L-783483
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    L-783483

    CAS:
    <p>L-783483 is an agonist of PPAR.</p>
    Fórmula:C22H21ClF3NO4S
    Pureza:98%
    Forma y color:Solid
    Peso molecular:487.92

    Ref: TM-T27784

  • ATR-IN-21
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    ATR-IN-21

    CAS:
    <p>ATR-IN-21, also known as compound 60, is a potent inhibitor of ATR, exhibiting an IC50 of less than 1000 nM [1].</p>
    Fórmula:C23H27N7O
    Pureza:98%
    Forma y color:Solid
    Peso molecular:417.51

    Ref: TM-T79031

  • HDAC8-IN-4
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    HDAC8-IN-4

    CAS:
    <p>HDAC8-IN-4 is a selective HDAC8 inhibitor, exhibiting inhibitory activity with IC50 values of 0.15 μM for HDAC8 and 12 μM for HDAC3 [1].</p>
    Fórmula:C17H14N2O2S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:342.44

    Ref: TM-T79082

  • Duocarmycin analog-2
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    Duocarmycin analog-2

    CAS:
    <p>Duocarmycin analog-2 is a potent DNA alkylating agent that exhibits antitumor effects and can be used in the synthesis of immunocouplers.</p>
    Fórmula:C29H23ClN4O3
    Forma y color:Solid
    Peso molecular:510.97

    Ref: TM-T63523

  • GNE-8505
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    GNE-8505

    CAS:
    <p>GNE-8505 is an orally available inhibitor of Dual leucine zipper kinase (DLK).</p>
    Fórmula:C21H24F3N5O
    Forma y color:Solid
    Peso molecular:419.44

    Ref: TM-T11440

  • CM-579 trihydrochloride (1846570-40-8 free base)
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    CM-579 trihydrochloride (1846570-40-8 free base)

    <p>CM-579 trihydrochloride is a first-in-class reversible and dual inhibitor of G9a and DNMT (IC50s: 16 nM, 32 nM) with potent in vitro cellular activity in a wide</p>
    Fórmula:C29H43Cl3N4O3
    Pureza:98%
    Forma y color:Solid
    Peso molecular:602.04

    Ref: TM-T10840

  • LCB-2853
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    LCB-2853

    CAS:
    <p>LCB-2853 is a potent thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor antagonist with antiplatelet aggregation, antivasospasm, and antithrombotic effects.</p>
    Fórmula:C21H24ClNO4S
    Pureza:97.15%
    Forma y color:Solid
    Peso molecular:421.94

    Ref: TM-T11825

  • ARN-21934
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    ARN-21934

    CAS:
    <p>ARN-21934 inhibits human topoisomerase II α/β; IC50=2μM; stronger than Etoposide (IC50=120μM) in DNA relaxation.</p>
    Fórmula:C21H24N6
    Pureza:99.8%
    Forma y color:Solid
    Peso molecular:360.46

    Ref: TM-T36968

  • XY-4
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    XY-4

    CAS:
    <p>XY-4, a derivative of 1-palmitoyl lysophosphatidic acid (1-palmitoyl LPA094) and an agonist of peroxisome proliferator-activated receptor γ (PPARγ), effectively</p>
    Fórmula:C19H37F2O6P
    Forma y color:Solid
    Peso molecular:430.46

    Ref: TM-T83882

  • Bocodepsin hydrochloride
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    Bocodepsin hydrochloride

    CAS:
    <p>Bocodepsin hydrochloride (OKI-179) is a selective HDAC inhibitor with antitumor properties, efficacious via oral administration.</p>
    Fórmula:C26H40ClN5O6S2
    Pureza:98%
    Forma y color:Solid
    Peso molecular:618.21

    Ref: TM-T79840

  • TP0480066
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    TP0480066

    CAS:
    <p>TP0480066 inhibits topoisomerase II, DNA gyrase (IC50=1.1nM), topo IV (IC50=62.89nM), effective against drug-resistant bacteria and N. gonorrhoeae.</p>
    Fórmula:C18H14FN3O5
    Forma y color:Solid
    Peso molecular:371.32

    Ref: TM-T61481

  • Topoisomerase IIα-IN-8
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    Topoisomerase IIα-IN-8

    CAS:
    <p>Topoisomerase IIα-IN-8 (compound 15) serves as a modest inhibitor of human DNA topoisomerase IIα (htIIα), exhibiting an inhibitory concentration (IC50) of 462 ± 38.0 μM [1].</p>
    Fórmula:C15H15FN6O
    Forma y color:Solid
    Peso molecular:314.324

    Ref: TM-T84739

  • ATR-IN-13
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    ATR-IN-13

    CAS:
    <p>ATR-IN-13 is a potent inhibitor of ATR kinases (IC50: 2 nM) and can be used to study ATR kinase-mediated diseases (e.g. proliferative diseases, cancer).</p>
    Fórmula:C24H24FN9O
    Forma y color:Solid
    Peso molecular:473.51

    Ref: TM-T63066

  • GSK-3484862
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    GSK-3484862

    CAS:
    <p>Gsk-3484862 is a non covalent inhibitor of DNA methyltransferase DNMT1 with anticancer activity.</p>
    Fórmula:C19H19N5OS
    Pureza:99.87% - 99.963%
    Forma y color:Solid
    Peso molecular:365.45

    Ref: TM-T11469

  • Peliglitazar
    Targetmol
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    Peliglitazar

    CAS:
    <p>Peliglitazar is a activator of α/γ peroxisome proliferator-activated receptor.</p>
    Fórmula:C30H30N2O7
    Forma y color:Solid
    Peso molecular:530.57

    Ref: TM-T28354